Click here to switch to the map view.

The map label for this gene is ycbL [H]

Identifier: 218905898

GI number: 218905898

Start: 4531541

End: 4532230

Strand: Reverse

Name: ycbL [H]

Synonym: BCAH820_4786

Alternate gene names: 218905898

Gene position: 4532230-4531541 (Counterclockwise)

Preceding gene: 218905899

Following gene: 218905897

Centisome position: 85.47

GC content: 34.93

Gene sequence:

>690_bases
TTGAAAAGAATTTTACTAATAGAAGATGAAGTAAGCATTGCAGAATTACAGCGAGATTATTTAGAAATTAATGATTTTCA
AGTTGATGTCGAACATTCAGGAGAAACAGGTTTACAAATGGCCCTGCAAGAAGACTACGATTTAATTATTTTAGATATTA
TGCTTCCGAAAATGAATGGATTTGAAATTTGTAAGCAAATTCGAGCTATAAAAGATATTCCGATTCTACTTGTTTCAGCA
AAAAAAGAAGATATAGATAAAATCCGCGGGCTCGGATTAGGAGCGGATGATTATATAACGAAACCGTTTAGCCCGAGTGA
GCTAGTAGCAAGAGTAAAAGCCCATATTGCTCGTTATGAAAGATTATTAGGAAATGTAAGTAAGCAACGCGATACGCTAT
ATATTCACGGAATCTCTATTGATCAAAGGGCGAGGAAAGTTTTTATAAACAATGAAGAAATCGCCTTTACAACGAAAGAA
TTTGATTTATTAACATTCTTTGTGACGCATCCAAACCAAGTATTAAATAAAGAACAGTTATTTGAACGCATCTGGGGATT
AGACTCCGCTGGTGATTTAGCAACTGTTGTCGTTCATATTAGAAAGTTACGTGAAAAAATTGAAAGAGATCCTGCTCACC
CGCAATATATTGAAACAGTGTGGGGGGCTGGTTATCGTTTTAATGTGTAG

Upstream 100 bases:

>100_bases
ATTGAAGAACATGGCGGGAATATTTGGGCGGAAAGCGAGCTTGGGGAAGGCACAAGCATTTTCTTCTCATTGGAAAAAGT
AGAGAAATGTGGTGAGTAAA

Downstream 100 bases:

>100_bases
GGAACCTGTCAAAGTTTTGGCAGGTTTTTTTTGTATGTGATCAAAAGGGGAGAATAGGTAATTTATGTTAAACTATAAAG
AGAGATAAAAACATAGGAGA

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MKRILLIEDEVSIAELQRDYLEINDFQVDVEHSGETGLQMALQEDYDLIILDIMLPKMNGFEICKQIRAIKDIPILLVSA
KKEDIDKIRGLGLGADDYITKPFSPSELVARVKAHIARYERLLGNVSKQRDTLYIHGISIDQRARKVFINNEEIAFTTKE
FDLLTFFVTHPNQVLNKEQLFERIWGLDSAGDLATVVVHIRKLREKIERDPAHPQYIETVWGAGYRFNV

Sequences:

>Translated_229_residues
MKRILLIEDEVSIAELQRDYLEINDFQVDVEHSGETGLQMALQEDYDLIILDIMLPKMNGFEICKQIRAIKDIPILLVSA
KKEDIDKIRGLGLGADDYITKPFSPSELVARVKAHIARYERLLGNVSKQRDTLYIHGISIDQRARKVFINNEEIAFTTKE
FDLLTFFVTHPNQVLNKEQLFERIWGLDSAGDLATVVVHIRKLREKIERDPAHPQYIETVWGAGYRFNV
>Mature_229_residues
MKRILLIEDEVSIAELQRDYLEINDFQVDVEHSGETGLQMALQEDYDLIILDIMLPKMNGFEICKQIRAIKDIPILLVSA
KKEDIDKIRGLGLGADDYITKPFSPSELVARVKAHIARYERLLGNVSKQRDTLYIHGISIDQRARKVFINNEEIAFTTKE
FDLLTFFVTHPNQVLNKEQLFERIWGLDSAGDLATVVVHIRKLREKIERDPAHPQYIETVWGAGYRFNV

Specific function: Member of the two-component regulatory system ycbM/ycbL [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=36.1233480176211, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=40.0862068965517, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=38.2222222222222, Blast_Score=153, Evalue=8e-39,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=37.280701754386, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1788394, Length=230, Percent_Identity=36.0869565217391, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1786911, Length=228, Percent_Identity=33.7719298245614, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=33.9055793991416, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=33.3333333333333, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=30.7017543859649, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=30.7017543859649, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=35.3982300884956, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=31.5789473684211, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=29.0178571428571, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787375, Length=185, Percent_Identity=30.2702702702703, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26438; Mature: 26438

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRILLIEDEVSIAELQRDYLEINDFQVDVEHSGETGLQMALQEDYDLIILDIMLPKMNG
CCEEEEEECCCHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHCCCCEEEEEEECCCCCH
FEICKQIRAIKDIPILLVSAKKEDIDKIRGLGLGADDYITKPFSPSELVARVKAHIARYE
HHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHH
RLLGNVSKQRDTLYIHGISIDQRARKVFINNEEIAFTTKEFDLLTFFVTHPNQVLNKEQL
HHHHCCCCCCCEEEEEECCCCCHHHEEEECCCEEEEEECCCEEEEEEEECCHHHCCHHHH
FERIWGLDSAGDLATVVVHIRKLREKIERDPAHPQYIETVWGAGYRFNV
HHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEECC
>Mature Secondary Structure
MKRILLIEDEVSIAELQRDYLEINDFQVDVEHSGETGLQMALQEDYDLIILDIMLPKMNG
CCEEEEEECCCHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHCCCCEEEEEEECCCCCH
FEICKQIRAIKDIPILLVSAKKEDIDKIRGLGLGADDYITKPFSPSELVARVKAHIARYE
HHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHH
RLLGNVSKQRDTLYIHGISIDQRARKVFINNEEIAFTTKEFDLLTFFVTHPNQVLNKEQL
HHHHCCCCCCCEEEEEECCCCCHHHEEEECCCEEEEEECCCEEEEEEEECCHHHCCHHHH
FERIWGLDSAGDLATVVVHIRKLREKIERDPAHPQYIETVWGAGYRFNV
HHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]