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The map label for this gene is ackA [H]

Identifier: 218905867

GI number: 218905867

Start: 4502087

End: 4503280

Strand: Reverse

Name: ackA [H]

Synonym: BCAH820_4755

Alternate gene names: 218905867

Gene position: 4503280-4502087 (Counterclockwise)

Preceding gene: 218905868

Following gene: 218905864

Centisome position: 84.92

GC content: 40.28

Gene sequence:

>1194_bases
ATGTCAAAAATCATCGCGATTAACGCAGGAAGCTCTTCCTTAAAATTCCAATTATTTGAAATGCCAAGTGAAACAGTATT
AACAAAAGGTTTAGTAGAACGTATCGGTTTAGAAGATAGTATCTTCACTATTACTGTAGATGGCGAAAAACAAAAAGAAA
TTACAAACATTCCAGATCACGCAGTAGCAGTTAATATGCTTCTTAAAAAATTAACTGAAAACGGAATCGTTAAATCTCTA
GATGAGATTGGCGGTATCGGTCACCGTGTTGTTCACGGCGGCGAAAAATTTGCTGACTCTGTTCTAATTACTGATGAAGT
ATTAGCTGATATCGAAGAATTAAGCGATTTAGCACCACTTCACAACCCAGCAAACGTTGTTGGTATTAAAGCATTCCAAG
AAGTATTACCAAACGTACCAGCAGTAGCAGTATTCGATACAGCATTCCACCAAACAATGCCGGAATCTGCATTCCTATAC
AGCTTACCATATGAGTACTATGAAAAATTCGGTATCCGTAAATACGGTTTCCACGGAACTTCTCATAAATATGTAACTGA
GCGTGCGGCTGAACTATTAGGTCGTCCACTTGAAAGCTTAAGCTTACTTTCTTGTCACTTAGGTAACGGTGCAAGTATCG
CAGCAGTAGAAGGCGGTAAATCTATCGATACTTCTATGGGCTTCACTCCACTTGCTGGTGTAACAATGGGTACACGTTCT
GGTAACCTTGACCCTGCGTTAATTCCATACATCATGGAAAAAACAGGTCAAACAGTAGAAGAAGTGGTTAATGTATTAAA
CAAGAAGAGTGGTATGTTAGGTCTTACTGGTTTCTCTAGTGACCTACGTGACATCATTGCGAAAGAAGAAGAAGGCGACC
ACCGTGCGAAAGTAGCACTTGATGTATTCGTAAGCCGTATCCACAAATACATCGGTTCTTACACTGCTCGTATGAAAGGT
GTAGACGCAATCATCTTTACAGCTGGTGTAGGTGAAAACAGTGCGATTATTCGTGAGCGCGTATTAGAAGGCCTTGAGTA
CATGGGCGTATACTTCGATGCAAAACGCAATAACGTATTCGGTGAGGAAGCATTCATCAACTTCCCACACTCTCCAGTAA
AAATTATTGTAATTCCAACTGACGAAGAAGTTATGATCGCTCGTGACGTACTACGTCTTGGGGATATTGGTTAA

Upstream 100 bases:

>100_bases
GATGAAACGTTTTCATATTTAGTAAATTTGATCAGATAAAATCGAGCGGTTTGTGGAAACATCCACACAACTACCAAGAG
AAAAAGGGGCGAAAGACTAG

Downstream 100 bases:

>100_bases
TATACTATATGAAAAGAAAGACGAGATCCTATAGGATTTCGTCTTTTTTCTATTGGAGATAGTTCAAAATTCCATCTGGA
TAGAGTACTTTTTTCTTCTG

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MSKIIAINAGSSSLKFQLFEMPSETVLTKGLVERIGLEDSIFTITVDGEKQKEITNIPDHAVAVNMLLKKLTENGIVKSL
DEIGGIGHRVVHGGEKFADSVLITDEVLADIEELSDLAPLHNPANVVGIKAFQEVLPNVPAVAVFDTAFHQTMPESAFLY
SLPYEYYEKFGIRKYGFHGTSHKYVTERAAELLGRPLESLSLLSCHLGNGASIAAVEGGKSIDTSMGFTPLAGVTMGTRS
GNLDPALIPYIMEKTGQTVEEVVNVLNKKSGMLGLTGFSSDLRDIIAKEEEGDHRAKVALDVFVSRIHKYIGSYTARMKG
VDAIIFTAGVGENSAIIRERVLEGLEYMGVYFDAKRNNVFGEEAFINFPHSPVKIIVIPTDEEVMIARDVLRLGDIG

Sequences:

>Translated_397_residues
MSKIIAINAGSSSLKFQLFEMPSETVLTKGLVERIGLEDSIFTITVDGEKQKEITNIPDHAVAVNMLLKKLTENGIVKSL
DEIGGIGHRVVHGGEKFADSVLITDEVLADIEELSDLAPLHNPANVVGIKAFQEVLPNVPAVAVFDTAFHQTMPESAFLY
SLPYEYYEKFGIRKYGFHGTSHKYVTERAAELLGRPLESLSLLSCHLGNGASIAAVEGGKSIDTSMGFTPLAGVTMGTRS
GNLDPALIPYIMEKTGQTVEEVVNVLNKKSGMLGLTGFSSDLRDIIAKEEEGDHRAKVALDVFVSRIHKYIGSYTARMKG
VDAIIFTAGVGENSAIIRERVLEGLEYMGVYFDAKRNNVFGEEAFINFPHSPVKIIVIPTDEEVMIARDVLRLGDIG
>Mature_396_residues
SKIIAINAGSSSLKFQLFEMPSETVLTKGLVERIGLEDSIFTITVDGEKQKEITNIPDHAVAVNMLLKKLTENGIVKSLD
EIGGIGHRVVHGGEKFADSVLITDEVLADIEELSDLAPLHNPANVVGIKAFQEVLPNVPAVAVFDTAFHQTMPESAFLYS
LPYEYYEKFGIRKYGFHGTSHKYVTERAAELLGRPLESLSLLSCHLGNGASIAAVEGGKSIDTSMGFTPLAGVTMGTRSG
NLDPALIPYIMEKTGQTVEEVVNVLNKKSGMLGLTGFSSDLRDIIAKEEEGDHRAKVALDVFVSRIHKYIGSYTARMKGV
DAIIFTAGVGENSAIIRERVLEGLEYMGVYFDAKRNNVFGEEAFINFPHSPVKIIVIPTDEEVMIARDVLRLGDIG

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI145693184, Length=396, Percent_Identity=43.6868686868687, Blast_Score=335, Evalue=4e-93,
Organism=Escherichia coli, GI1788633, Length=399, Percent_Identity=44.3609022556391, Blast_Score=334, Evalue=6e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 43217; Mature: 43086

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2 ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIIAINAGSSSLKFQLFEMPSETVLTKGLVERIGLEDSIFTITVDGEKQKEITNIPDH
CCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHCCCCHH
AVAVNMLLKKLTENGIVKSLDEIGGIGHRVVHGGEKFADSVLITDEVLADIEELSDLAPL
HHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHCCCHHHHCCEEEHHHHHHHHHHHHHHCCC
HNPANVVGIKAFQEVLPNVPAVAVFDTAFHQTMPESAFLYSLPYEYYEKFGIRKYGFHGT
CCCCHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCCCCEEEECCHHHHHHCCCEEECCCCC
SHKYVTERAAELLGRPLESLSLLSCHLGNGASIAAVEGGKSIDTSMGFTPLAGVTMGTRS
CCHHHHHHHHHHHCCCHHHHHHHHEECCCCCEEEEECCCCCCCCCCCCCCCCCEEECCCC
GNLDPALIPYIMEKTGQTVEEVVNVLNKKSGMLGLTGFSSDLRDIIAKEEEGDHRAKVAL
CCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCCCCCHHHHHHH
DVFVSRIHKYIGSYTARMKGVDAIIFTAGVGENSAIIRERVLEGLEYMGVYFDAKRNNVF
HHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHEEEEECCCCCCC
GEEAFINFPHSPVKIIVIPTDEEVMIARDVLRLGDIG
CCHHEEECCCCCEEEEEEECCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
SKIIAINAGSSSLKFQLFEMPSETVLTKGLVERIGLEDSIFTITVDGEKQKEITNIPDH
CEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHCCCCHH
AVAVNMLLKKLTENGIVKSLDEIGGIGHRVVHGGEKFADSVLITDEVLADIEELSDLAPL
HHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHCCCHHHHCCEEEHHHHHHHHHHHHHHCCC
HNPANVVGIKAFQEVLPNVPAVAVFDTAFHQTMPESAFLYSLPYEYYEKFGIRKYGFHGT
CCCCHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCCCCEEEECCHHHHHHCCCEEECCCCC
SHKYVTERAAELLGRPLESLSLLSCHLGNGASIAAVEGGKSIDTSMGFTPLAGVTMGTRS
CCHHHHHHHHHHHCCCHHHHHHHHEECCCCCEEEEECCCCCCCCCCCCCCCCCEEECCCC
GNLDPALIPYIMEKTGQTVEEVVNVLNKKSGMLGLTGFSSDLRDIIAKEEEGDHRAKVAL
CCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCCCCCHHHHHHH
DVFVSRIHKYIGSYTARMKGVDAIIFTAGVGENSAIIRERVLEGLEYMGVYFDAKRNNVF
HHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHEEEEECCCCCCC
GEEAFINFPHSPVKIIVIPTDEEVMIARDVLRLGDIG
CCHHEEECCCCCEEEEEEECCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]