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The map label for this gene is isdE [H]

Identifier: 218905772

GI number: 218905772

Start: 4411640

End: 4412521

Strand: Reverse

Name: isdE [H]

Synonym: BCAH820_4660

Alternate gene names: 218905772

Gene position: 4412521-4411640 (Counterclockwise)

Preceding gene: 218905773

Following gene: 218905771

Centisome position: 83.21

GC content: 35.03

Gene sequence:

>882_bases
TTGAGAGTGAAGAAAATTGCAAGTGTACTAATGGCTATCATTTTATTAGTAAGTATAGCTGGATGCTCGGCGCCTAAAAA
AGAAGCAGCAAAACAGGTGAAGAGTGAGAGTAAAGAGAGAGTTGTTGCTACGACAGTTGCTGTTACTGAAATTATGGATG
CGTTAGAAGTAGATTTAGTTGGTGTTCCAACGAGTACGAAAGATTTACCAAAGAGATATAAAGGGTTACCTGAAGTCGGG
AATCCGATGAGTCCTGATATGGAAAAGGTAAAATCATTAAAGCCGTCAGAAGTATTATCTGTTACAACACTTGAATATGA
ATTAAAGCCAGTTTTTGATGGTGTAGGTATGAAAGCAAACTTTGTAGACTTAACTAGTTTAAAAAATATGCAAAATGCCA
TTAGTAATTTAGGTAAGCAATATGGGCGTGAAAAACAAGCTGAAGCAGTTGTAACGAAGTTAGATAAAAAAGTCGCTAGC
ATTCGAAAAGAAGTAAAAGGAAAGAGAGAACCGACAGTACTTATTTTATTAGGTGTGCCGGGAAGTTATTTAGTAGCAAC
AGAGCATTCTTATATTGGGGATTTAGTGAAACAACTAGGTGGTAAAAATATTGTGCAAGGTGAAAAAGTAGAATATTTAG
CTTCTAATACAGAGTACTTAAAGAAAGCTGATCCAGATATTATTTTACGAGCAGCTCATGGTATGCCTGATGAAGTTGTA
AAAATGTTTGATAAAGAATTTAAAACGAATGACATTTGGAAGCACTTCGCTGCAGTTAAAAATAATCGTGTTTACGATTT
AGAAGAGCGTTTATTTGGAACGACAGGAAATTTAGCAGCAATTGAAGCGTTAGATGAATTGAAAAAAATGATGTATCCGT
GA

Upstream 100 bases:

>100_bases
AGTTCGTAAATATAGAGCAGGTAGATTGTAATTTTTGGAGTCTTGATGCATGTTCGCGTGCATCAAGACTTGTTTCATAT
TGTTTGGAAAGGAGTGGTGA

Downstream 100 bases:

>100_bases
TGCATTTTCATATAAAGGAAGAGTAGAATGAATAAAAAAACTTGGAGTTTCCTCATTGTTACTGCATTACTTATCGTTAT
GACATCATTGTCAGCGATGA

Product: iron compound ABC transporter, iron compound-binding protein

Products: NA

Alternate protein names: Iron-regulated surface determinant protein E; Staphylococcal iron-regulated protein F [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MRVKKIASVLMAIILLVSIAGCSAPKKEAAKQVKSESKERVVATTVAVTEIMDALEVDLVGVPTSTKDLPKRYKGLPEVG
NPMSPDMEKVKSLKPSEVLSVTTLEYELKPVFDGVGMKANFVDLTSLKNMQNAISNLGKQYGREKQAEAVVTKLDKKVAS
IRKEVKGKREPTVLILLGVPGSYLVATEHSYIGDLVKQLGGKNIVQGEKVEYLASNTEYLKKADPDIILRAAHGMPDEVV
KMFDKEFKTNDIWKHFAAVKNNRVYDLEERLFGTTGNLAAIEALDELKKMMYP

Sequences:

>Translated_293_residues
MRVKKIASVLMAIILLVSIAGCSAPKKEAAKQVKSESKERVVATTVAVTEIMDALEVDLVGVPTSTKDLPKRYKGLPEVG
NPMSPDMEKVKSLKPSEVLSVTTLEYELKPVFDGVGMKANFVDLTSLKNMQNAISNLGKQYGREKQAEAVVTKLDKKVAS
IRKEVKGKREPTVLILLGVPGSYLVATEHSYIGDLVKQLGGKNIVQGEKVEYLASNTEYLKKADPDIILRAAHGMPDEVV
KMFDKEFKTNDIWKHFAAVKNNRVYDLEERLFGTTGNLAAIEALDELKKMMYP
>Mature_293_residues
MRVKKIASVLMAIILLVSIAGCSAPKKEAAKQVKSESKERVVATTVAVTEIMDALEVDLVGVPTSTKDLPKRYKGLPEVG
NPMSPDMEKVKSLKPSEVLSVTTLEYELKPVFDGVGMKANFVDLTSLKNMQNAISNLGKQYGREKQAEAVVTKLDKKVAS
IRKEVKGKREPTVLILLGVPGSYLVATEHSYIGDLVKQLGGKNIVQGEKVEYLASNTEYLKKADPDIILRAAHGMPDEVV
KMFDKEFKTNDIWKHFAAVKNNRVYDLEERLFGTTGNLAAIEALDELKKMMYP

Specific function: Involved in heme (porphyrin) scavenging. Binds Fe(2+) and Fe(3+) heme but the largest fraction is Fe(2+) heme. Functions as a high-affinity heme binding protein and probably has a role in relaying heme-iron from cell wall-anchored isd proteins receptors t

COG id: COG0614

COG function: function code P; ABC-type Fe3+-hydroxamate transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe/B12 periplasmic-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019957
- InterPro:   IPR002491 [H]

Pfam domain/function: PF01497 Peripla_BP_2 [H]

EC number: NA

Molecular weight: Translated: 32326; Mature: 32326

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50983 FE_B12_PBP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVKKIASVLMAIILLVSIAGCSAPKKEAAKQVKSESKERVVATTVAVTEIMDALEVDLV
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEE
GVPTSTKDLPKRYKGLPEVGNPMSPDMEKVKSLKPSEVLSVTTLEYELKPVFDGVGMKAN
ECCCCCHHHHHHHCCCCCCCCCCCCCHHHHHCCCHHHHEEEEEEEEEHHHHHCCCCCCCC
FVDLTSLKNMQNAISNLGKQYGREKQAEAVVTKLDKKVASIRKEVKGKREPTVLILLGVP
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECC
GSYLVATEHSYIGDLVKQLGGKNIVQGEKVEYLASNTEYLKKADPDIILRAAHGMPDEVV
CCEEEEECHHHHHHHHHHHCCCCCCCCCHHHHHHCCHHHHHHCCCCCEEEECCCCCHHHH
KMFDKEFKTNDIWKHFAAVKNNRVYDLEERLFGTTGNLAAIEALDELKKMMYP
HHHHHHCCHHHHHHHHHHHHCCCCEEHHHHHCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRVKKIASVLMAIILLVSIAGCSAPKKEAAKQVKSESKERVVATTVAVTEIMDALEVDLV
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEE
GVPTSTKDLPKRYKGLPEVGNPMSPDMEKVKSLKPSEVLSVTTLEYELKPVFDGVGMKAN
ECCCCCHHHHHHHCCCCCCCCCCCCCHHHHHCCCHHHHEEEEEEEEEHHHHHCCCCCCCC
FVDLTSLKNMQNAISNLGKQYGREKQAEAVVTKLDKKVASIRKEVKGKREPTVLILLGVP
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECC
GSYLVATEHSYIGDLVKQLGGKNIVQGEKVEYLASNTEYLKKADPDIILRAAHGMPDEVV
CCEEEEECHHHHHHHHHHHCCCCCCCCCHHHHHHCCHHHHHHCCCCCEEEECCCCCHHHH
KMFDKEFKTNDIWKHFAAVKNNRVYDLEERLFGTTGNLAAIEALDELKKMMYP
HHHHHHCCHHHHHHHHHHHHCCCCEEHHHHHCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA