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The map label for this gene is dnaC [H]

Identifier: 218905522

GI number: 218905522

Start: 4172274

End: 4173596

Strand: Reverse

Name: dnaC [H]

Synonym: BCAH820_4407

Alternate gene names: 218905522

Gene position: 4173596-4172274 (Counterclockwise)

Preceding gene: 218905523

Following gene: 218905521

Centisome position: 78.71

GC content: 36.66

Gene sequence:

>1323_bases
ATGAGTAATGATATGATTCGCAACGTAGAAGCAGAGCAAAGTGTTTTAGGGAGCATTATTCAAGAAGGCGATTTAATTAA
AGATTGTCAGCTAAAGGCAAAGCAGTTTTCTTTACCAACACATCAAATGATTTTTAAAGCGATGAGAGAACTAGAGGATG
CTGAAATACCAATTGACCTTGTTGCTCTTATTGGAAAGTTCGATGAAGGTTTCATACATCAAATTGGCGGAATTGAATTC
TTTGTAAACCTAACAGAAATTGTAACAACAACTAAGAATTTCTCGTATCATGAAGGGCTTGTGATTGAAGCTTGGAAGAT
GAGACATGCGCAGGAGGTTGCTGGTAACTTATACAACGATCTTCAGCAAGATAGAGATATGAGTGCTATTAGTAAATCGA
TTGACGAACTAAGTGCCATTGAAGAAACAGGTTATTCAGATGAATTTAACTTGAAAGAAACGCTTGTTGATCTGTATAAA
AAAATGCAAATTGACGTAGGAGATTTAACCGGTATTCCAACTGGTTACGACGATTTGAACAGAATGACAGCAGGTTTACA
AGAAGGAGATTTAATAATTGTCGGTGCCCGTCCTTCCATGGGGAAAACAGCATTTGTATTAAACGTTGCTTTCCATGCAG
CAAGTGCTCAGACAGCAACAGGGGTCTTTTCATTAGAGATGGGAGAAGAACAGTTACTTAAGCGAATGATCTCAAGTACT
GGAAATATAGATGCTACGAAATTAAAGAATCCTAAAAAATTATGTAATTTAAAGGATTGGGAAAAGATTAGCCAAGCTAT
GGGCTTGATAAATGATTTACCACTAGAAATATACGATAAGGCAAATGTAACAATGCAAGAGATTTACGCAAAGACTAGGA
AATTAAAGCGTAAATATCCAGACAAAAAGGTGCTAGTCGCAATTGATTACTTGCAGCTTATTGTAGGAGATCCAAAGCAT
AAAGGGAATCGCATGCAAGAGATTGGGGAGATTAGCCGCAAGCTAAAACTTATGGCAAGAGAACTAAATGTATGTGTCGT
TGCATTATCGCAGTTAAGCCGTGCTGTTGAGAGTAGGCAAGATAAGAGGCCATTACTATCAGACTTACGTGAGAATGGTC
AAATTGAGCAAGATGCCGATTTAATAGCATTCTTATATCGTGAAGATTATTATGACCGTGAAACAGAAAATAAAAACATA
ACAGAAATTATTTTAGCGAAACAGAGAAATGGTCCAGTAGGTGTTGTGGAATTAGCATTTATTAAAGAATTTAGTAAGTT
CGTAGGCTTGGATCGGAAATTTGATAAACAACAGGAGGCTTAA

Upstream 100 bases:

>100_bases
CTACTCAAAACGTATTACAGCAACAAGAAGCATGGAAACAAAACATTCCAACAGAAGAAGAGCTTGCAGCGCTTAATCAG
CAGAATGCGTGGATGGCACA

Downstream 100 bases:

>100_bases
TGATGTTGTTACGTCAGGAAGTAGAACGTAGAAAGCTAGCGATTATTCGCAAACTATTGGGATTAGGGTTAGCTGAGATT
AATGGGCAAACATTAGACCA

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSNDMIRNVEAEQSVLGSIIQEGDLIKDCQLKAKQFSLPTHQMIFKAMRELEDAEIPIDLVALIGKFDEGFIHQIGGIEF
FVNLTEIVTTTKNFSYHEGLVIEAWKMRHAQEVAGNLYNDLQQDRDMSAISKSIDELSAIEETGYSDEFNLKETLVDLYK
KMQIDVGDLTGIPTGYDDLNRMTAGLQEGDLIIVGARPSMGKTAFVLNVAFHAASAQTATGVFSLEMGEEQLLKRMISST
GNIDATKLKNPKKLCNLKDWEKISQAMGLINDLPLEIYDKANVTMQEIYAKTRKLKRKYPDKKVLVAIDYLQLIVGDPKH
KGNRMQEIGEISRKLKLMARELNVCVVALSQLSRAVESRQDKRPLLSDLRENGQIEQDADLIAFLYREDYYDRETENKNI
TEIILAKQRNGPVGVVELAFIKEFSKFVGLDRKFDKQQEA

Sequences:

>Translated_440_residues
MSNDMIRNVEAEQSVLGSIIQEGDLIKDCQLKAKQFSLPTHQMIFKAMRELEDAEIPIDLVALIGKFDEGFIHQIGGIEF
FVNLTEIVTTTKNFSYHEGLVIEAWKMRHAQEVAGNLYNDLQQDRDMSAISKSIDELSAIEETGYSDEFNLKETLVDLYK
KMQIDVGDLTGIPTGYDDLNRMTAGLQEGDLIIVGARPSMGKTAFVLNVAFHAASAQTATGVFSLEMGEEQLLKRMISST
GNIDATKLKNPKKLCNLKDWEKISQAMGLINDLPLEIYDKANVTMQEIYAKTRKLKRKYPDKKVLVAIDYLQLIVGDPKH
KGNRMQEIGEISRKLKLMARELNVCVVALSQLSRAVESRQDKRPLLSDLRENGQIEQDADLIAFLYREDYYDRETENKNI
TEIILAKQRNGPVGVVELAFIKEFSKFVGLDRKFDKQQEA
>Mature_439_residues
SNDMIRNVEAEQSVLGSIIQEGDLIKDCQLKAKQFSLPTHQMIFKAMRELEDAEIPIDLVALIGKFDEGFIHQIGGIEFF
VNLTEIVTTTKNFSYHEGLVIEAWKMRHAQEVAGNLYNDLQQDRDMSAISKSIDELSAIEETGYSDEFNLKETLVDLYKK
MQIDVGDLTGIPTGYDDLNRMTAGLQEGDLIIVGARPSMGKTAFVLNVAFHAASAQTATGVFSLEMGEEQLLKRMISSTG
NIDATKLKNPKKLCNLKDWEKISQAMGLINDLPLEIYDKANVTMQEIYAKTRKLKRKYPDKKVLVAIDYLQLIVGDPKHK
GNRMQEIGEISRKLKLMARELNVCVVALSQLSRAVESRQDKRPLLSDLRENGQIEQDADLIAFLYREDYYDRETENKNIT
EIILAKQRNGPVGVVELAFIKEFSKFVGLDRKFDKQQEA

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=435, Percent_Identity=39.5402298850575, Blast_Score=269, Evalue=3e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 49797; Mature: 49666

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNDMIRNVEAEQSVLGSIIQEGDLIKDCQLKAKQFSLPTHQMIFKAMRELEDAEIPIDL
CCCCHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHH
VALIGKFDEGFIHQIGGIEFFVNLTEIVTTTKNFSYHEGLVIEAWKMRHAQEVAGNLYND
HHHHHCCCCHHHHHHCCHHHEEEHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHH
LQQDRDMSAISKSIDELSAIEETGYSDEFNLKETLVDLYKKMQIDVGDLTGIPTGYDDLN
HHHHCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHCCCCCCCHHHHH
RMTAGLQEGDLIIVGARPSMGKTAFVLNVAFHAASAQTATGVFSLEMGEEQLLKRMISST
HHHCCCCCCCEEEEECCCCCCCCEEEEEHHHHHCCCHHHCCEEEEECCHHHHHHHHHHCC
GNIDATKLKNPKKLCNLKDWEKISQAMGLINDLPLEIYDKANVTMQEIYAKTRKLKRKYP
CCCCHHHCCCHHHHCCCHHHHHHHHHHHHHHCCCHHEECCCCCHHHHHHHHHHHHHHHCC
DKKVLVAIDYLQLIVGDPKHKGNRMQEIGEISRKLKLMARELNVCVVALSQLSRAVESRQ
CCEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DKRPLLSDLRENGQIEQDADLIAFLYREDYYDRETENKNITEIILAKQRNGPVGVVELAF
CCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHEEEECCCCCCCHHHHHH
IKEFSKFVGLDRKFDKQQEA
HHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SNDMIRNVEAEQSVLGSIIQEGDLIKDCQLKAKQFSLPTHQMIFKAMRELEDAEIPIDL
CCCHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHH
VALIGKFDEGFIHQIGGIEFFVNLTEIVTTTKNFSYHEGLVIEAWKMRHAQEVAGNLYND
HHHHHCCCCHHHHHHCCHHHEEEHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHH
LQQDRDMSAISKSIDELSAIEETGYSDEFNLKETLVDLYKKMQIDVGDLTGIPTGYDDLN
HHHHCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHCCCCCCCHHHHH
RMTAGLQEGDLIIVGARPSMGKTAFVLNVAFHAASAQTATGVFSLEMGEEQLLKRMISST
HHHCCCCCCCEEEEECCCCCCCCEEEEEHHHHHCCCHHHCCEEEEECCHHHHHHHHHHCC
GNIDATKLKNPKKLCNLKDWEKISQAMGLINDLPLEIYDKANVTMQEIYAKTRKLKRKYP
CCCCHHHCCCHHHHCCCHHHHHHHHHHHHHHCCCHHEECCCCCHHHHHHHHHHHHHHHCC
DKKVLVAIDYLQLIVGDPKHKGNRMQEIGEISRKLKLMARELNVCVVALSQLSRAVESRQ
CCEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DKRPLLSDLRENGQIEQDADLIAFLYREDYYDRETENKNITEIILAKQRNGPVGVVELAF
CCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHEEEECCCCCCCHHHHHH
IKEFSKFVGLDRKFDKQQEA
HHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]