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The map label for this gene is metH [H]

Identifier: 218905390

GI number: 218905390

Start: 4060596

End: 4063994

Strand: Reverse

Name: metH [H]

Synonym: BCAH820_4274

Alternate gene names: 218905390

Gene position: 4063994-4060596 (Counterclockwise)

Preceding gene: 218905391

Following gene: 218905389

Centisome position: 76.64

GC content: 39.01

Gene sequence:

>3399_bases
ATGAAATGTATAGAAGAAAAATTACAAAATAACATCTTACTATTAGATGGTGCAATGGGAACGATGATCCAGCAAGAGGA
CTTAACTGCGGAAGATTTCGGAGGGGAAGAGTATGAAGGTTGTAATGAGTATTTAGTAGAAACAAGACCAGATGTTATTT
TAAAGATTCATAAAGCTTACATTGAAGCTGGAGCGGATATTATTGAAACGAATACATTTGGGGCAACAAATATTGTACTA
AGTGATTATGAGTTATCTCATTTAGACGAAGAGCTAAATGAGAAGGCAGCGCGTTTAGCGAAGCAAGCAGTCAAAGAAAG
TGGGAAGGAAGTATATGTTGCCGGAGCAATGGGACCGACAACGAAAGCGATTAGTGTTACTGGTGGTGTAACGTTTGAAG
AATTAATTGAAGCTTATACACGGCAAGCAAGAGGATTGTTGAAAGGAGAAGTTGATGTATTACTAGTTGAGACGAGTCAA
GATATGCGTAACGTGAAGGCTGCTTATATTGGAATTCAAGCAGCCTTTGACGAACTAAAAAAAATTGTACCTATCATGAT
TTCGGGAACGATTGAACCGATGGGAACGACTCTGGCTGGGCAAACAATTGAGGCTTTTTACTTATCGGTAGAACATATGA
AGCCATTATCTGTTGGATTAAACTGTGCGACTGGTCCGGAGTTTATGAGAGATCATATTCGTTCACTATCTGATTTGTCG
GAGTGTTACATTTCTTGTTATCCAAATGCAGGTCTTCCTGATGAAGATGGACATTATCATGAATCTCCATCTTCTCTCGC
TGAAAAAGTGAAGCGATTTGCTGAAGAAGGATGGGTTAATATTATCGGTGGTTGTTGTGGCACAACACCAGAACATATAA
AAGCAATGAAAGAAGCACTAGCATCCCTAAAGCCTCGTGAACATCATGAACGAGAAGGTCATGGAGTTAGTGGATTAGAG
GCACTGCAATATGATGACTCTATGAGACCATTATTTGTTGGTGAAAGAACAAACGTTATTGGATCACGTAAATTTAAACG
ATTAGTAGCAGAAGGGAAATTTGAAGAGGCTGCTGAAGTCGCAAGAGCGCAAGTGAAGAAAAATGCTCATATTATTGATA
TTTGTATGGCAGACCCGGACCGGGATGAAATAGAAGATATGGAAAACTTCTTGGCAGAAGTTACGAAAGTGTTAAAAGTA
CCGATTATGATTGACTCAACAGATGAACATGTGATGGAGCGAGCTCTTACTTATATTCAAGGGAAAGCTGTTATTAATTC
AATTAACTTAGAAGATGGAGAAGAACGATTTATAAAAGTGACGCCGCTTCTTCAGAAATATGGTGCCGCTATTGTTGTAG
GAACAATTGATGAAGACGGTATGGCAGTAAGTGCAGAAAGAAAACTCGAAATTGCGAAAAGAAGTTATGAGTTATTGACC
ACGAAATATGGTATACGCCCGTCAGATATTATTTTTGATGCACTCGTGTTTCCTGTAGGGACAGGGGATGAAGAATATAT
TGGCTCGGCGGCAGCGACAATAGAAGGGATTCGTCTTATTAAAGAAGCATTGCCAGAATGTTTAACGATTTTAGGTGTAA
GTAACATATCATTTGGTTTACCACCAGCTGGCCGCGAAGTATTAAATTCGGTCTTCTTATACCATGCAACGAAAGCAGGA
TTAGACTACGCGATTGTGAATACGGAAAAATTAGAGCGCTATGCATCAATTCCTGATGAAGAAAAACGGCTTGCAGATGC
ATTACTTTTTGAAACGACGCAAGAGACGCTAGAAGAATTTACAAACTTTTATCGCGTGGCAAAAAAGAAAGATGTTGTTG
TCCAAGAAACATTAACTCTTGATGAAAGGTTAGCTAATTACATTGTAGAAGGGACAAAACAAGGGTTACACGAAGATTTA
AGCCTCGCGCTTACAGAAGGAAGAAAACCTTTGGATATTATTAATGGCCCACTTATGACAGGGATGGATGAGGTAGGACG
ATTATTTAATAATAATGAGCTAATCGTTGCTGAAGTATTGCAAAGTGCTGAAAGTATGAAAGCTGCTGTAAGTTATTTAG
AGCCACATATGGAATCTAGCGATAGTGCAAAAAAAGGGAAAGTATTATTAGCAACTGTTAAAGGTGACGTACATGATATT
GGGAAAAACCTCGTTGAAATTATTTTAGCGAATAACGGATATGAGATTATTAATTTAGGAATCAATGTTCGGTCGGATCG
AATTGTTCAAGAAGTACAAGAAAAGAAGCCTGATATTATAGGTCTTTCTGGTTTATTAGTAAAATCGGCTCAACAAATGG
TAACGACTGCAGAAGATTTAAAAGCTGCGGATATTGATATTCCAATTGTTGTAGGCGGGGCAGCGCTAACGAGAAAGTTT
ACAGATAATCGCATTTCGCCATCTTATAAAGGGCTCGTATGTTATGCAAGTGATGCGATGACGGGGCTGGATATTATTAA
TAAGCTTCAAAAAGAAGAAGAGCGTGAGAAGATGAAGCAGGATAAAAAAGAACGTCATCTTCATATCGTAACAAAAGAAG
AAAAGAAAATAGAAATTCCAGCAGTAATTGAGCCATTACCAAAATCAGAGGTTATGGTACCTGATTCAACGAAGCGAATT
GTATTACGAGATGTTCCCGCCCTTCATCTCGCACCATTTCTGAATAGACAAATGCTACTTGGACATCATCTTGGATTAAA
AGGAAGCGTGAAGAAGCTTTTGAAAGAGGGAGATAAAAGAGCACATGAATTAAATGATTTAATAGATGAATTATTGCAGG
AAGGACAATCTTGGTTAAAACCGAAAGCGGTGTATCAATTTTTCCCAGCGCAAAGTGACGGACAAAACATTGTAATATAT
GATCCAGAAGATCATACGCGTGTTATAGAGCGTTTCACATTCCCAAGGCAAGGAAGGGCTCCATATCGTACTTTAGGTGA
TTATTTACGACCAATTGGAGATGAGATGGACTATGTTGCTTTCCTATCTGTTACGGTTGGAGAAGGCGTTCGGGGCATTG
CTGAAGAGTGGAAGGCGAAAGGTGATTATTTACGCAGTCATGCCATTCAATCGTTAGCGCTTGAACTAGCAGAAGGACTT
GCTGAAAAAACACATATGCTTATTCGTGATCGCTGGGGTATTCCAGATTCACCAGAATTGACGATGGAAGAACGTTTCCG
TACGAAATATAGAGGGATACGCGTGTCCTTCGGTTATCCAGCATGTCCAGAACTTGCGGATCAAGAAAAGTTATTTCGAC
TTATTCATCCAGAAGAAATAGGTATTTCATTAACGGAAGGGTTTATGATGGAACCAGAAGCATCTGTAACGGCTATGGTA
TTTTCTCACCCCGAGGCAAGATATTTTAGTGTATTATAG

Upstream 100 bases:

>100_bases
ACGGTATTTATCTTATTACGCCATTTCTAAAATATGAAATTACAGAACATCTTGTTAAATATGTGAGAGAAAAGCAAGAA
GTGAAAGAAGGTATTAATTG

Downstream 100 bases:

>100_bases
TCTAGAAGGGGGAGACGTATGAAAAAAATAGTCTTTACAGGTGGCGGTTCGGCAGGGCATGTAACACCTAATTTAGCCAT
TATTCCATATTTAAAGGAAG

Product: 5-methyltetrahydrofolate--homocysteine methyltransferase

Products: NA

Alternate protein names: 5-methyltetrahydrofolate--homocysteine methyltransferase; Methionine synthase, vitamin-B12 dependent; MS [H]

Number of amino acids: Translated: 1132; Mature: 1132

Protein sequence:

>1132_residues
MKCIEEKLQNNILLLDGAMGTMIQQEDLTAEDFGGEEYEGCNEYLVETRPDVILKIHKAYIEAGADIIETNTFGATNIVL
SDYELSHLDEELNEKAARLAKQAVKESGKEVYVAGAMGPTTKAISVTGGVTFEELIEAYTRQARGLLKGEVDVLLVETSQ
DMRNVKAAYIGIQAAFDELKKIVPIMISGTIEPMGTTLAGQTIEAFYLSVEHMKPLSVGLNCATGPEFMRDHIRSLSDLS
ECYISCYPNAGLPDEDGHYHESPSSLAEKVKRFAEEGWVNIIGGCCGTTPEHIKAMKEALASLKPREHHEREGHGVSGLE
ALQYDDSMRPLFVGERTNVIGSRKFKRLVAEGKFEEAAEVARAQVKKNAHIIDICMADPDRDEIEDMENFLAEVTKVLKV
PIMIDSTDEHVMERALTYIQGKAVINSINLEDGEERFIKVTPLLQKYGAAIVVGTIDEDGMAVSAERKLEIAKRSYELLT
TKYGIRPSDIIFDALVFPVGTGDEEYIGSAAATIEGIRLIKEALPECLTILGVSNISFGLPPAGREVLNSVFLYHATKAG
LDYAIVNTEKLERYASIPDEEKRLADALLFETTQETLEEFTNFYRVAKKKDVVVQETLTLDERLANYIVEGTKQGLHEDL
SLALTEGRKPLDIINGPLMTGMDEVGRLFNNNELIVAEVLQSAESMKAAVSYLEPHMESSDSAKKGKVLLATVKGDVHDI
GKNLVEIILANNGYEIINLGINVRSDRIVQEVQEKKPDIIGLSGLLVKSAQQMVTTAEDLKAADIDIPIVVGGAALTRKF
TDNRISPSYKGLVCYASDAMTGLDIINKLQKEEEREKMKQDKKERHLHIVTKEEKKIEIPAVIEPLPKSEVMVPDSTKRI
VLRDVPALHLAPFLNRQMLLGHHLGLKGSVKKLLKEGDKRAHELNDLIDELLQEGQSWLKPKAVYQFFPAQSDGQNIVIY
DPEDHTRVIERFTFPRQGRAPYRTLGDYLRPIGDEMDYVAFLSVTVGEGVRGIAEEWKAKGDYLRSHAIQSLALELAEGL
AEKTHMLIRDRWGIPDSPELTMEERFRTKYRGIRVSFGYPACPELADQEKLFRLIHPEEIGISLTEGFMMEPEASVTAMV
FSHPEARYFSVL

Sequences:

>Translated_1132_residues
MKCIEEKLQNNILLLDGAMGTMIQQEDLTAEDFGGEEYEGCNEYLVETRPDVILKIHKAYIEAGADIIETNTFGATNIVL
SDYELSHLDEELNEKAARLAKQAVKESGKEVYVAGAMGPTTKAISVTGGVTFEELIEAYTRQARGLLKGEVDVLLVETSQ
DMRNVKAAYIGIQAAFDELKKIVPIMISGTIEPMGTTLAGQTIEAFYLSVEHMKPLSVGLNCATGPEFMRDHIRSLSDLS
ECYISCYPNAGLPDEDGHYHESPSSLAEKVKRFAEEGWVNIIGGCCGTTPEHIKAMKEALASLKPREHHEREGHGVSGLE
ALQYDDSMRPLFVGERTNVIGSRKFKRLVAEGKFEEAAEVARAQVKKNAHIIDICMADPDRDEIEDMENFLAEVTKVLKV
PIMIDSTDEHVMERALTYIQGKAVINSINLEDGEERFIKVTPLLQKYGAAIVVGTIDEDGMAVSAERKLEIAKRSYELLT
TKYGIRPSDIIFDALVFPVGTGDEEYIGSAAATIEGIRLIKEALPECLTILGVSNISFGLPPAGREVLNSVFLYHATKAG
LDYAIVNTEKLERYASIPDEEKRLADALLFETTQETLEEFTNFYRVAKKKDVVVQETLTLDERLANYIVEGTKQGLHEDL
SLALTEGRKPLDIINGPLMTGMDEVGRLFNNNELIVAEVLQSAESMKAAVSYLEPHMESSDSAKKGKVLLATVKGDVHDI
GKNLVEIILANNGYEIINLGINVRSDRIVQEVQEKKPDIIGLSGLLVKSAQQMVTTAEDLKAADIDIPIVVGGAALTRKF
TDNRISPSYKGLVCYASDAMTGLDIINKLQKEEEREKMKQDKKERHLHIVTKEEKKIEIPAVIEPLPKSEVMVPDSTKRI
VLRDVPALHLAPFLNRQMLLGHHLGLKGSVKKLLKEGDKRAHELNDLIDELLQEGQSWLKPKAVYQFFPAQSDGQNIVIY
DPEDHTRVIERFTFPRQGRAPYRTLGDYLRPIGDEMDYVAFLSVTVGEGVRGIAEEWKAKGDYLRSHAIQSLALELAEGL
AEKTHMLIRDRWGIPDSPELTMEERFRTKYRGIRVSFGYPACPELADQEKLFRLIHPEEIGISLTEGFMMEPEASVTAMV
FSHPEARYFSVL
>Mature_1132_residues
MKCIEEKLQNNILLLDGAMGTMIQQEDLTAEDFGGEEYEGCNEYLVETRPDVILKIHKAYIEAGADIIETNTFGATNIVL
SDYELSHLDEELNEKAARLAKQAVKESGKEVYVAGAMGPTTKAISVTGGVTFEELIEAYTRQARGLLKGEVDVLLVETSQ
DMRNVKAAYIGIQAAFDELKKIVPIMISGTIEPMGTTLAGQTIEAFYLSVEHMKPLSVGLNCATGPEFMRDHIRSLSDLS
ECYISCYPNAGLPDEDGHYHESPSSLAEKVKRFAEEGWVNIIGGCCGTTPEHIKAMKEALASLKPREHHEREGHGVSGLE
ALQYDDSMRPLFVGERTNVIGSRKFKRLVAEGKFEEAAEVARAQVKKNAHIIDICMADPDRDEIEDMENFLAEVTKVLKV
PIMIDSTDEHVMERALTYIQGKAVINSINLEDGEERFIKVTPLLQKYGAAIVVGTIDEDGMAVSAERKLEIAKRSYELLT
TKYGIRPSDIIFDALVFPVGTGDEEYIGSAAATIEGIRLIKEALPECLTILGVSNISFGLPPAGREVLNSVFLYHATKAG
LDYAIVNTEKLERYASIPDEEKRLADALLFETTQETLEEFTNFYRVAKKKDVVVQETLTLDERLANYIVEGTKQGLHEDL
SLALTEGRKPLDIINGPLMTGMDEVGRLFNNNELIVAEVLQSAESMKAAVSYLEPHMESSDSAKKGKVLLATVKGDVHDI
GKNLVEIILANNGYEIINLGINVRSDRIVQEVQEKKPDIIGLSGLLVKSAQQMVTTAEDLKAADIDIPIVVGGAALTRKF
TDNRISPSYKGLVCYASDAMTGLDIINKLQKEEEREKMKQDKKERHLHIVTKEEKKIEIPAVIEPLPKSEVMVPDSTKRI
VLRDVPALHLAPFLNRQMLLGHHLGLKGSVKKLLKEGDKRAHELNDLIDELLQEGQSWLKPKAVYQFFPAQSDGQNIVIY
DPEDHTRVIERFTFPRQGRAPYRTLGDYLRPIGDEMDYVAFLSVTVGEGVRGIAEEWKAKGDYLRSHAIQSLALELAEGL
AEKTHMLIRDRWGIPDSPELTMEERFRTKYRGIRVSFGYPACPELADQEKLFRLIHPEEIGISLTEGFMMEPEASVTAMV
FSHPEARYFSVL

Specific function: Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate [H]

COG id: COG1410

COG function: function code E; Methionine synthase I, cobalamin-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 pterin-binding domain [H]

Homologues:

Organism=Homo sapiens, GI169790923, Length=1217, Percent_Identity=36.7296631059984, Blast_Score=705, Evalue=0.0,
Organism=Escherichia coli, GI1790450, Length=1191, Percent_Identity=37.8673383711167, Blast_Score=733, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17535405, Length=1217, Percent_Identity=37.0583401807724, Blast_Score=720, Evalue=0.0,

Paralogues:

None

Copy number: 513 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006158
- InterPro:   IPR011005
- InterPro:   IPR003759
- InterPro:   IPR011822
- InterPro:   IPR000489
- InterPro:   IPR003726
- InterPro:   IPR004223 [H]

Pfam domain/function: PF02310 B12-binding; PF02607 B12-binding_2; PF02965 Met_synt_B12; PF00809 Pterin_bind; PF02574 S-methyl_trans [H]

EC number: =2.1.1.13 [H]

Molecular weight: Translated: 125944; Mature: 125944

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS50974 ADOMET_ACTIVATION ; PS50970 HCY ; PS50972 PTERIN_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCIEEKLQNNILLLDGAMGTMIQQEDLTAEDFGGEEYEGCNEYLVETRPDVILKIHKAY
CCHHHHHHHCCEEEEECCCCCCEECCCCCHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHH
IEAGADIIETNTFGATNIVLSDYELSHLDEELNEKAARLAKQAVKESGKEVYVAGAMGPT
HHCCCCEEECCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
TKAISVTGGVTFEELIEAYTRQARGLLKGEVDVLLVETSQDMRNVKAAYIGIQAAFDELK
CCEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHH
KIVPIMISGTIEPMGTTLAGQTIEAFYLSVEHMKPLSVGLNCATGPEFMRDHIRSLSDLS
HHHHHHEECCCCCCCCHHCCCHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHHHHHH
ECYISCYPNAGLPDEDGHYHESPSSLAEKVKRFAEEGWVNIIGGCCGTTPEHIKAMKEAL
HHHEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHH
ASLKPREHHEREGHGVSGLEALQYDDSMRPLFVGERTNVIGSRKFKRLVAEGKFEEAAEV
HHCCCCHHHHCCCCCCCCHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHCCCHHHHHHH
ARAQVKKNAHIIDICMADPDRDEIEDMENFLAEVTKVLKVPIMIDSTDEHVMERALTYIQ
HHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHH
GKAVINSINLEDGEERFIKVTPLLQKYGAAIVVGTIDEDGMAVSAERKLEIAKRSYELLT
HHHHEEECCCCCCCHHEEEEEHHHHHCCCEEEEEEECCCCCEECHHHHHHHHHHHHHHHH
TKYGIRPSDIIFDALVFPVGTGDEEYIGSAAATIEGIRLIKEALPECLTILGVSNISFGL
HHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PPAGREVLNSVFLYHATKAGLDYAIVNTEKLERYASIPDEEKRLADALLFETTQETLEEF
CCCHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
TNFYRVAKKKDVVVQETLTLDERLANYIVEGTKQGLHEDLSLALTEGRKPLDIINGPLMT
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHC
GMDEVGRLFNNNELIVAEVLQSAESMKAAVSYLEPHMESSDSAKKGKVLLATVKGDVHDI
CHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCHHHH
GKNLVEIILANNGYEIINLGINVRSDRIVQEVQEKKPDIIGLSGLLVKSAQQMVTTAEDL
HHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHH
KAADIDIPIVVGGAALTRKFTDNRISPSYKGLVCYASDAMTGLDIINKLQKEEEREKMKQ
HHCCCCEEEEECCHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
DKKERHLHIVTKEEKKIEIPAVIEPLPKSEVMVPDSTKRIVLRDVPALHLAPFLNRQMLL
HHHHCCEEEEECCCCCEECCHHHCCCCCCCEECCCCCCEEEEECCCHHHHHHHHCHHHHH
GHHLGLKGSVKKLLKEGDKRAHELNDLIDELLQEGQSWLKPKAVYQFFPAQSDGQNIVIY
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCEEEEE
DPEDHTRVIERFTFPRQGRAPYRTLGDYLRPIGDEMDYVAFLSVTVGEGVRGIAEEWKAK
CCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEHHCCCHHHHHHHHHHH
GDYLRSHAIQSLALELAEGLAEKTHMLIRDRWGIPDSPELTMEERFRTKYRGIRVSFGYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCEEEECCCC
ACPELADQEKLFRLIHPEEIGISLTEGFMMEPEASVTAMVFSHPEARYFSVL
CCCCCCCHHHHHHHCCHHHCCCEECCCEEECCCCCEEEEEECCCCCHHCCCC
>Mature Secondary Structure
MKCIEEKLQNNILLLDGAMGTMIQQEDLTAEDFGGEEYEGCNEYLVETRPDVILKIHKAY
CCHHHHHHHCCEEEEECCCCCCEECCCCCHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHH
IEAGADIIETNTFGATNIVLSDYELSHLDEELNEKAARLAKQAVKESGKEVYVAGAMGPT
HHCCCCEEECCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
TKAISVTGGVTFEELIEAYTRQARGLLKGEVDVLLVETSQDMRNVKAAYIGIQAAFDELK
CCEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHH
KIVPIMISGTIEPMGTTLAGQTIEAFYLSVEHMKPLSVGLNCATGPEFMRDHIRSLSDLS
HHHHHHEECCCCCCCCHHCCCHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHHHHHH
ECYISCYPNAGLPDEDGHYHESPSSLAEKVKRFAEEGWVNIIGGCCGTTPEHIKAMKEAL
HHHEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHH
ASLKPREHHEREGHGVSGLEALQYDDSMRPLFVGERTNVIGSRKFKRLVAEGKFEEAAEV
HHCCCCHHHHCCCCCCCCHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHCCCHHHHHHH
ARAQVKKNAHIIDICMADPDRDEIEDMENFLAEVTKVLKVPIMIDSTDEHVMERALTYIQ
HHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHH
GKAVINSINLEDGEERFIKVTPLLQKYGAAIVVGTIDEDGMAVSAERKLEIAKRSYELLT
HHHHEEECCCCCCCHHEEEEEHHHHHCCCEEEEEEECCCCCEECHHHHHHHHHHHHHHHH
TKYGIRPSDIIFDALVFPVGTGDEEYIGSAAATIEGIRLIKEALPECLTILGVSNISFGL
HHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PPAGREVLNSVFLYHATKAGLDYAIVNTEKLERYASIPDEEKRLADALLFETTQETLEEF
CCCHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
TNFYRVAKKKDVVVQETLTLDERLANYIVEGTKQGLHEDLSLALTEGRKPLDIINGPLMT
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHC
GMDEVGRLFNNNELIVAEVLQSAESMKAAVSYLEPHMESSDSAKKGKVLLATVKGDVHDI
CHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCHHHH
GKNLVEIILANNGYEIINLGINVRSDRIVQEVQEKKPDIIGLSGLLVKSAQQMVTTAEDL
HHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHH
KAADIDIPIVVGGAALTRKFTDNRISPSYKGLVCYASDAMTGLDIINKLQKEEEREKMKQ
HHCCCCEEEEECCHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
DKKERHLHIVTKEEKKIEIPAVIEPLPKSEVMVPDSTKRIVLRDVPALHLAPFLNRQMLL
HHHHCCEEEEECCCCCEECCHHHCCCCCCCEECCCCCCEEEEECCCHHHHHHHHCHHHHH
GHHLGLKGSVKKLLKEGDKRAHELNDLIDELLQEGQSWLKPKAVYQFFPAQSDGQNIVIY
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCEEEEE
DPEDHTRVIERFTFPRQGRAPYRTLGDYLRPIGDEMDYVAFLSVTVGEGVRGIAEEWKAK
CCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEHHCCCHHHHHHHHHHH
GDYLRSHAIQSLALELAEGLAEKTHMLIRDRWGIPDSPELTMEERFRTKYRGIRVSFGYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCEEEECCCC
ACPELADQEKLFRLIHPEEIGISLTEGFMMEPEASVTAMVFSHPEARYFSVL
CCCCCCCHHHHHHHCCHHHCCCEECCCEEECCCCCEEEEEECCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]