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The map label for this gene is bioH [C]

Identifier: 218904884

GI number: 218904884

Start: 3594828

End: 3595601

Strand: Reverse

Name: bioH [C]

Synonym: BCAH820_3768

Alternate gene names: 218904884

Gene position: 3595601-3594828 (Counterclockwise)

Preceding gene: 218904885

Following gene: 218904883

Centisome position: 67.81

GC content: 32.17

Gene sequence:

>774_bases
ATGTATTTTGAATATAAGAATCGAAAGGTTTTTTACAATATAGAAGGGTCGGGTCCTGTCATATTATTTTTACACGGCCT
TGGAGGAAACGCAAATAATTGGTTATATCAAAGGCAATATTTTAAGAAAAAATGGACAGTGATCTCTCTGGATTTACCGG
GGCATGGAAAATCTGAAGGGCTAGAAATTAACTTTAAAGAATATGTAAATGTTTTGTATGAGTTATGTAAGTATTTAAAG
TTACAAAAAGTAGTCATTTGTGGACTTTCAAAAGGGGCTAGGGTAGGTATTGATTTTGCTATTCAATATCCAGACTTTGT
TTCTAGCTTAATTATTGTAAATGCATTTCCCTACTTGGAGCCTGAAGATCGAAAGAAACGGCTTGAAGTATATGATTTAC
TTAGCTTACATGATAACGGGAAAAAATGGGCGGATACGTTGTTGGAGGAGATGGGAGTAGCCAGTAATGAAGTAATTGTC
AGGGGATTTTATCAATCTTTACAGTCTATTAATCCGGTGCATATTCAAAGATTATTTGCTGAATTAGTAGATTATGATCA
AAGACCACTTCTTTTAAATATTTCATGTTCCACTTTAATTATAAGAGGAGAAAATGATGATTTTGTTCCTGAGAAATATG
TAAGAGAGTTTGAAAGACGTTTGAAAAATACAACTTTTATTGAGTTTAAAAATAGTGGACACTTACCTTATTTAGAACAG
CCGAGCAGCTTTAATATGACCGTAGAAAAATTTTTGAATCATGTAATTAATTAA

Upstream 100 bases:

>100_bases
ATGGTGTAACGGAAACAGTCGAATGGCTAGAAAGAGAACCGTTTTGGATATATCCATTCAAAGATAAAAATAAGTGATGC
TACAGCTGAAGGTGATGAGT

Downstream 100 bases:

>100_bases
TACTATTATTACAGTCAATACTGTTATTAGCGAGTAAAATAAAGTTAGTTTTGAGAGGAGGAAACTATATGGAATGGAAA
CCAAATCGTGCAGATAAGAC

Product: hydrolase, alpha/beta fold family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MYFEYKNRKVFYNIEGSGPVILFLHGLGGNANNWLYQRQYFKKKWTVISLDLPGHGKSEGLEINFKEYVNVLYELCKYLK
LQKVVICGLSKGARVGIDFAIQYPDFVSSLIIVNAFPYLEPEDRKKRLEVYDLLSLHDNGKKWADTLLEEMGVASNEVIV
RGFYQSLQSINPVHIQRLFAELVDYDQRPLLLNISCSTLIIRGENDDFVPEKYVREFERRLKNTTFIEFKNSGHLPYLEQ
PSSFNMTVEKFLNHVIN

Sequences:

>Translated_257_residues
MYFEYKNRKVFYNIEGSGPVILFLHGLGGNANNWLYQRQYFKKKWTVISLDLPGHGKSEGLEINFKEYVNVLYELCKYLK
LQKVVICGLSKGARVGIDFAIQYPDFVSSLIIVNAFPYLEPEDRKKRLEVYDLLSLHDNGKKWADTLLEEMGVASNEVIV
RGFYQSLQSINPVHIQRLFAELVDYDQRPLLLNISCSTLIIRGENDDFVPEKYVREFERRLKNTTFIEFKNSGHLPYLEQ
PSSFNMTVEKFLNHVIN
>Mature_257_residues
MYFEYKNRKVFYNIEGSGPVILFLHGLGGNANNWLYQRQYFKKKWTVISLDLPGHGKSEGLEINFKEYVNVLYELCKYLK
LQKVVICGLSKGARVGIDFAIQYPDFVSSLIIVNAFPYLEPEDRKKRLEVYDLLSLHDNGKKWADTLLEEMGVASNEVIV
RGFYQSLQSINPVHIQRLFAELVDYDQRPLLLNISCSTLIIRGENDDFVPEKYVREFERRLKNTTFIEFKNSGHLPYLEQ
PSSFNMTVEKFLNHVIN

Specific function: Not Clear. Seems To Be Implicated In The Early Steps Of Biotin Biosynthesis. [C]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dmpD/todF/xylF esterase family [H]

Homologues:

Organism=Escherichia coli, GI1789817, Length=247, Percent_Identity=23.0769230769231, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 29979; Mature: 29979

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYFEYKNRKVFYNIEGSGPVILFLHGLGGNANNWLYQRQYFKKKWTVISLDLPGHGKSEG
CCEEECCCEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCC
LEINFKEYVNVLYELCKYLKLQKVVICGLSKGARVGIDFAIQYPDFVSSLIIVNAFPYLE
EEEEHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEEEEECHHHHHHHHHHHCCCCCC
PEDRKKRLEVYDLLSLHDNGKKWADTLLEEMGVASNEVIVRGFYQSLQSINPVHIQRLFA
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHH
ELVDYDQRPLLLNISCSTLIIRGENDDFVPEKYVREFERRLKNTTFIEFKNSGHLPYLEQ
HHHCCCCCCEEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCC
PSSFNMTVEKFLNHVIN
CCCCCEEHHHHHHHHCC
>Mature Secondary Structure
MYFEYKNRKVFYNIEGSGPVILFLHGLGGNANNWLYQRQYFKKKWTVISLDLPGHGKSEG
CCEEECCCEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCC
LEINFKEYVNVLYELCKYLKLQKVVICGLSKGARVGIDFAIQYPDFVSSLIIVNAFPYLE
EEEEHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEEEEECHHHHHHHHHHHCCCCCC
PEDRKKRLEVYDLLSLHDNGKKWADTLLEEMGVASNEVIVRGFYQSLQSINPVHIQRLFA
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHH
ELVDYDQRPLLLNISCSTLIIRGENDDFVPEKYVREFERRLKNTTFIEFKNSGHLPYLEQ
HHHCCCCCCEEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCC
PSSFNMTVEKFLNHVIN
CCCCCEEHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]