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The map label for this gene is gabP [H]

Identifier: 218904849

GI number: 218904849

Start: 3564627

End: 3565058

Strand: Reverse

Name: gabP [H]

Synonym: BCAH820_3733

Alternate gene names: 218904849

Gene position: 3565058-3564627 (Counterclockwise)

Preceding gene: 218904850

Following gene: 218904848

Centisome position: 67.23

GC content: 33.33

Gene sequence:

>432_bases
TTGAACAGTAGTGGTGTTCCAGTTCGGGCCGTTTTATTCGGAACGTTCTTCGCTTATATTGGAGTTGTTTTTAGTTACAT
ATCTCCAGATAAAGTCTTTTTATTTTTAGTGAATGCCTCTGGTGGGATTGCGTTACTCGTTTATCTCGTTATAGCTATTT
CGCATTTAAAGATTCGTAAAAAAATGGGAAGGGTAGAACAACAAAATTTGAAAGTGAAAATGTGGTTTTTCCCGTATGTG
ACGTATGTTACAATTGCAGCTATTATAGCAGTTTTAATTGCGATGCTTGCCATTGAATCTTTACGTTCACAAGCACTTTT
GACGATGCTTGTCACTGTTCTTATAATCATTTCTTATTTTATTTTTAATAGAAATAAAAATAGTACAGTGTTGAATACTA
AAAGTAAGAATGAGGAATCTGTCCGATTTTAA

Upstream 100 bases:

>100_bases
ACAGCTGTACTTTCTTGTTTAAATTCTGGTTTATATACGAACTCAAGAATGCTTTTTTCGATGGCGGAAAGAGGAGATGC
TCCAAAGGCGTTCTTGAAAT

Downstream 100 bases:

>100_bases
TTTCTTGTTTTCTAAGAAATGCTACATCCAACCATTGGTAGAAAAGAGTAATTACTATTGTCATAGTGAATATAAACTTT
TTTCTTGACTTTTTATACGA

Product: GABA permease

Products: Proton [Cytoplasm]; 4-aminobutyrate [Cytoplasm] [C]

Alternate protein names: 4-amino butyrate transport carrier; Gamma-aminobutyrate permease [H]

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MNSSGVPVRAVLFGTFFAYIGVVFSYISPDKVFLFLVNASGGIALLVYLVIAISHLKIRKKMGRVEQQNLKVKMWFFPYV
TYVTIAAIIAVLIAMLAIESLRSQALLTMLVTVLIIISYFIFNRNKNSTVLNTKSKNEESVRF

Sequences:

>Translated_143_residues
MNSSGVPVRAVLFGTFFAYIGVVFSYISPDKVFLFLVNASGGIALLVYLVIAISHLKIRKKMGRVEQQNLKVKMWFFPYV
TYVTIAAIIAVLIAMLAIESLRSQALLTMLVTVLIIISYFIFNRNKNSTVLNTKSKNEESVRF
>Mature_143_residues
MNSSGVPVRAVLFGTFFAYIGVVFSYISPDKVFLFLVNASGGIALLVYLVIAISHLKIRKKMGRVEQQNLKVKMWFFPYV
TYVTIAAIIAVLIAMLAIESLRSQALLTMLVTVLIIISYFIFNRNKNSTVLNTKSKNEESVRF

Specific function: Transporter for GABA [H]

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789017, Length=127, Percent_Identity=40.9448818897638, Blast_Score=91, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840
- InterPro:   IPR011265 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 16076; Mature: 16076

Theoretical pI: Translated: 10.72; Mature: 10.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSSGVPVRAVLFGTFFAYIGVVFSYISPDKVFLFLVNASGGIALLVYLVIAISHLKIRK
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHH
KMGRVEQQNLKVKMWFFPYVTYVTIAAIIAVLIAMLAIESLRSQALLTMLVTVLIIISYF
HHCCHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFNRNKNSTVLNTKSKNEESVRF
HHCCCCCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MNSSGVPVRAVLFGTFFAYIGVVFSYISPDKVFLFLVNASGGIALLVYLVIAISHLKIRK
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHH
KMGRVEQQNLKVKMWFFPYVTYVTIAAIIAVLIAMLAIESLRSQALLTMLVTVLIIISYF
HHCCHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFNRNKNSTVLNTKSKNEESVRF
HHCCCCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 4-aminobutyrate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 4-aminobutyrate [Periplasm] = Proton [Cytoplasm] + 4-aminobutyrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8951816; 8969499; 9384377 [H]