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The map label for this gene is tkt2 [H]

Identifier: 218904815

GI number: 218904815

Start: 3532770

End: 3534812

Strand: Reverse

Name: tkt2 [H]

Synonym: BCAH820_3699

Alternate gene names: 218904815

Gene position: 3534812-3532770 (Counterclockwise)

Preceding gene: 218904816

Following gene: 218904814

Centisome position: 66.66

GC content: 40.77

Gene sequence:

>2043_bases
ATGTATAAAACGTTTACTAATATAAGCGAAGGGAAGAATAGCATGTCACATTCAATCGAACAACTTTCTATCAACACGAT
TCGCACATTATCCATCGATGCGATTGAAAAAGCAAACTCTGGTCACCCAGGAATGCCAATGGGTGCAGCACCAATGGCTT
ATACATTATGGACTCAATTTATGAAACACAATCCAAATAACCCAACGTGGTTTAACCGTGATCGTTTCGTATTATCTGCA
GGTCATGGTTCAATGTTATTATACAGCCTACTTCACCTATCTGGTTATGATGTAACAATGGATGACTTAAAGAACTTCCG
TCAATGGGGAAGCAAAACTCCAGGGCATCCTGAGTACGGTCATACAGCTGGTGTAGATGCAACTACTGGTCCACTTGGAC
AAGGTATTGCAACTGCTGTAGGTATGGCAATGGCAGAAAGACATTTAGCTGCTAAATATAACCGTGATGCGTATAATGTA
GTAGATCATTATACATACGCTATTTGTGGTGATGGAGATTTAATGGAAGGCGTTTCTGCTGAAGCATCTTCATTAGCTGC
TCATTTACAATTAGGTCGTCTTGTTGTGCTTTATGATTCAAACGATATTTCATTAGATGGCGATTTAAATCGTTCATTCT
CTGAAAGTGTAGAAGATCGTTACAAAGCATACGGATGGCAAGTAATCCGTGTTGAGGATGGAAACGATATTGAAGCTATC
GCGAAAGCAATCGAAGAAGCGAAAGCTGACGAAAAACGCCCAACGCTAATTGAAGTAAGAACGACAATTGGTTTCGGTTC
TCCAAACAAATCAGGAAAATCAGCTTCACATGGTTCTCCACTTGGTGTAGAAGAAACAAAGTTAACGAAAGAAGCATACG
CTTGGACTGCTGAACAAGACTTCCATGTAGCAGAAGAAGTATATGAAAACTTCCGTAAAACAGTACAAGATGTTGGTGAA
ACTGTACAAGCTGAGTGGAATACTATGCTAGGTGAATATGCACAAGCATATCCAGAATTAGCAAACGAACTGCAAGCAGC
AATGAACGGTCTTCTTCCAGAAGGTTGGGAGCAAAACTTACCAACTTATGAATTAGGATCAAAAGCAGCAACTCGTAATT
CTTCAGGTGCTGTAATTAATGCAATTGCAGAGTCTGTACCATCATTCTTCGGTGGATCTGCTGACCTTGCTGGTTCTAAC
AAAACATACATGAATAACGAAAAAGACTTTACAAGAGATGATTACAGCGGTAAAAACATTTGGTACGGTGTACGTGAGTT
CGCAATGGGTGCAGCAATGAACGGTATTGCACTACATGGTGGTTTAAAAACTTACGGTGGTACGTTCTTCGTATTCTCTG
ACTACTTACGCCCAGCAATTCGTCTTGCAGCATTAATGCAATTGCCGGTAACGTATGTATTCACACACGACAGTATCGCT
GTTGGTGAAGATGGTCCAACACATGAACCAATCGAGCAATTAGCAGCGCTACGTGCAATGCCAAATGTATCTGTTATTCG
TCCAGCTGACGGTAACGAATCTGTTGCAGCTTGGAGACTAGCTCTAGAATCTACAAACAAACCAACTGCTTTAGTATTAA
CTCGTCAAGATCTTCCAACATTAGAAGGTGCAAAAGACGATACGTATGAAAAAGTAGCAAAAGGTGCGTATGTAGTTTCT
GCAAGCAAGAAAGAAACAGCTGATGTAATCTTACTTGCAACTGGATCTGAAGTAAGTCTAGCTGTTGAAGCTCAAAAAGC
ATTAGCAGTAGACGGCGTTGATGCATCTGTTGTCAGCATGCCATCTATGGATCGCTTTGAAGCTCAAACAGCTGAGTACA
AAGAATCTGTATTACCAAAAGCAGTAACAAAACGTTTCGCAATCGAAATGGGTGCTACATTCGGATGGCACCGTTACGTA
GGTCTTGAAGGAGATGTGTTAGGTATCGATACATTCGGTGCTTCTGCTCCTGGTGAGAAGATTATGGAAGAGTATGGATT
TACTGTAGAGAACGTTGTTCGTAAAGTAAAAGAAATGCTTTAA

Upstream 100 bases:

>100_bases
ACATTCCCGGAATCATTGATTTTTTTATAAAAAATCAAAAAAACATCAACATATTTGTCGATACATGTTGTATAATCTTG
CGTGGGAAGCTATCATATAA

Downstream 100 bases:

>100_bases
TGATTTTAGAAAAATCTCTCCGGCATGGAGAGGTTTTTCTATGTAAATGAGTTTTTTCGACAGAAAAAGTTTTTTCTCTC
TCCGCAGTCAGACAATCATT

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 680; Mature: 680

Protein sequence:

>680_residues
MYKTFTNISEGKNSMSHSIEQLSINTIRTLSIDAIEKANSGHPGMPMGAAPMAYTLWTQFMKHNPNNPTWFNRDRFVLSA
GHGSMLLYSLLHLSGYDVTMDDLKNFRQWGSKTPGHPEYGHTAGVDATTGPLGQGIATAVGMAMAERHLAAKYNRDAYNV
VDHYTYAICGDGDLMEGVSAEASSLAAHLQLGRLVVLYDSNDISLDGDLNRSFSESVEDRYKAYGWQVIRVEDGNDIEAI
AKAIEEAKADEKRPTLIEVRTTIGFGSPNKSGKSASHGSPLGVEETKLTKEAYAWTAEQDFHVAEEVYENFRKTVQDVGE
TVQAEWNTMLGEYAQAYPELANELQAAMNGLLPEGWEQNLPTYELGSKAATRNSSGAVINAIAESVPSFFGGSADLAGSN
KTYMNNEKDFTRDDYSGKNIWYGVREFAMGAAMNGIALHGGLKTYGGTFFVFSDYLRPAIRLAALMQLPVTYVFTHDSIA
VGEDGPTHEPIEQLAALRAMPNVSVIRPADGNESVAAWRLALESTNKPTALVLTRQDLPTLEGAKDDTYEKVAKGAYVVS
ASKKETADVILLATGSEVSLAVEAQKALAVDGVDASVVSMPSMDRFEAQTAEYKESVLPKAVTKRFAIEMGATFGWHRYV
GLEGDVLGIDTFGASAPGEKIMEEYGFTVENVVRKVKEML

Sequences:

>Translated_680_residues
MYKTFTNISEGKNSMSHSIEQLSINTIRTLSIDAIEKANSGHPGMPMGAAPMAYTLWTQFMKHNPNNPTWFNRDRFVLSA
GHGSMLLYSLLHLSGYDVTMDDLKNFRQWGSKTPGHPEYGHTAGVDATTGPLGQGIATAVGMAMAERHLAAKYNRDAYNV
VDHYTYAICGDGDLMEGVSAEASSLAAHLQLGRLVVLYDSNDISLDGDLNRSFSESVEDRYKAYGWQVIRVEDGNDIEAI
AKAIEEAKADEKRPTLIEVRTTIGFGSPNKSGKSASHGSPLGVEETKLTKEAYAWTAEQDFHVAEEVYENFRKTVQDVGE
TVQAEWNTMLGEYAQAYPELANELQAAMNGLLPEGWEQNLPTYELGSKAATRNSSGAVINAIAESVPSFFGGSADLAGSN
KTYMNNEKDFTRDDYSGKNIWYGVREFAMGAAMNGIALHGGLKTYGGTFFVFSDYLRPAIRLAALMQLPVTYVFTHDSIA
VGEDGPTHEPIEQLAALRAMPNVSVIRPADGNESVAAWRLALESTNKPTALVLTRQDLPTLEGAKDDTYEKVAKGAYVVS
ASKKETADVILLATGSEVSLAVEAQKALAVDGVDASVVSMPSMDRFEAQTAEYKESVLPKAVTKRFAIEMGATFGWHRYV
GLEGDVLGIDTFGASAPGEKIMEEYGFTVENVVRKVKEML
>Mature_680_residues
MYKTFTNISEGKNSMSHSIEQLSINTIRTLSIDAIEKANSGHPGMPMGAAPMAYTLWTQFMKHNPNNPTWFNRDRFVLSA
GHGSMLLYSLLHLSGYDVTMDDLKNFRQWGSKTPGHPEYGHTAGVDATTGPLGQGIATAVGMAMAERHLAAKYNRDAYNV
VDHYTYAICGDGDLMEGVSAEASSLAAHLQLGRLVVLYDSNDISLDGDLNRSFSESVEDRYKAYGWQVIRVEDGNDIEAI
AKAIEEAKADEKRPTLIEVRTTIGFGSPNKSGKSASHGSPLGVEETKLTKEAYAWTAEQDFHVAEEVYENFRKTVQDVGE
TVQAEWNTMLGEYAQAYPELANELQAAMNGLLPEGWEQNLPTYELGSKAATRNSSGAVINAIAESVPSFFGGSADLAGSN
KTYMNNEKDFTRDDYSGKNIWYGVREFAMGAAMNGIALHGGLKTYGGTFFVFSDYLRPAIRLAALMQLPVTYVFTHDSIA
VGEDGPTHEPIEQLAALRAMPNVSVIRPADGNESVAAWRLALESTNKPTALVLTRQDLPTLEGAKDDTYEKVAKGAYVVS
ASKKETADVILLATGSEVSLAVEAQKALAVDGVDASVVSMPSMDRFEAQTAEYKESVLPKAVTKRFAIEMGATFGWHRYV
GLEGDVLGIDTFGASAPGEKIMEEYGFTVENVVRKVKEML

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=498, Percent_Identity=27.1084337349398, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI4507521, Length=498, Percent_Identity=27.1084337349398, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI133778974, Length=589, Percent_Identity=25.4668930390492, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI225637459, Length=680, Percent_Identity=21.1764705882353, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI225637463, Length=577, Percent_Identity=21.8370883882149, Blast_Score=101, Evalue=3e-21,
Organism=Homo sapiens, GI225637461, Length=577, Percent_Identity=21.8370883882149, Blast_Score=100, Evalue=4e-21,
Organism=Escherichia coli, GI48994911, Length=661, Percent_Identity=50.9833585476551, Blast_Score=672, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=661, Percent_Identity=49.4704992435704, Blast_Score=650, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=668, Percent_Identity=24.8502994011976, Blast_Score=150, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6325331, Length=670, Percent_Identity=48.8059701492537, Blast_Score=631, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319593, Length=671, Percent_Identity=47.6900149031297, Blast_Score=610, Evalue=1e-175,
Organism=Drosophila melanogaster, GI24666278, Length=573, Percent_Identity=27.5741710296684, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI45551847, Length=669, Percent_Identity=24.0657698056801, Blast_Score=162, Evalue=6e-40,
Organism=Drosophila melanogaster, GI45550715, Length=669, Percent_Identity=24.0657698056801, Blast_Score=162, Evalue=6e-40,
Organism=Drosophila melanogaster, GI24645119, Length=641, Percent_Identity=23.7129485179407, Blast_Score=148, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 74026; Mature: 74026

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2 ; PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKTFTNISEGKNSMSHSIEQLSINTIRTLSIDAIEKANSGHPGMPMGAAPMAYTLWTQF
CCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
MKHNPNNPTWFNRDRFVLSAGHGSMLLYSLLHLSGYDVTMDDLKNFRQWGSKTPGHPEYG
HHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCCCCC
HTAGVDATTGPLGQGIATAVGMAMAERHLAAKYNRDAYNVVDHYTYAICGDGDLMEGVSA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCEEEEEECCCHHHHCCCH
EASSLAAHLQLGRLVVLYDSNDISLDGDLNRSFSESVEDRYKAYGWQVIRVEDGNDIEAI
HHHHHHHHHHHCCEEEEECCCCEEECCCCCCHHHHHHHHHHHHCCEEEEEEECCCCHHHH
AKAIEEAKADEKRPTLIEVRTTIGFGSPNKSGKSASHGSPLGVEETKLTKEAYAWTAEQD
HHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHEECCCCC
FHVAEEVYENFRKTVQDVGETVQAEWNTMLGEYAQAYPELANELQAAMNGLLPEGWEQNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCC
PTYELGSKAATRNSSGAVINAIAESVPSFFGGSADLAGSNKTYMNNEKDFTRDDYSGKNI
CCCCCCCCHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
WYGVREFAMGAAMNGIALHGGLKTYGGTFFVFSDYLRPAIRLAALMQLPVTYVFTHDSIA
HHHHHHHHHHHHCCCEEEECCHHHCCCEEEEHHHHHHHHHHHHHHHHCCEEEEEECCCEE
VGEDGPTHEPIEQLAALRAMPNVSVIRPADGNESVAAWRLALESTNKPTALVLTRQDLPT
ECCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCEEHEEEHHCCCCCEEEEEECCCCCC
LEGAKDDTYEKVAKGAYVVSASKKETADVILLATGSEVSLAVEAQKALAVDGVDASVVSM
CCCCCCHHHHHHHCCEEEEECCCCCCCCEEEEEECCCEEEEEEHHHHHEECCCCCHHCCC
PSMDRFEAQTAEYKESVLPKAVTKRFAIEMGATFGWHRYVGLEGDVLGIDTFGASAPGEK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEECCCCCCCHHH
IMEEYGFTVENVVRKVKEML
HHHHHCCCHHHHHHHHHHHC
>Mature Secondary Structure
MYKTFTNISEGKNSMSHSIEQLSINTIRTLSIDAIEKANSGHPGMPMGAAPMAYTLWTQF
CCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
MKHNPNNPTWFNRDRFVLSAGHGSMLLYSLLHLSGYDVTMDDLKNFRQWGSKTPGHPEYG
HHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCCCCC
HTAGVDATTGPLGQGIATAVGMAMAERHLAAKYNRDAYNVVDHYTYAICGDGDLMEGVSA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCEEEEEECCCHHHHCCCH
EASSLAAHLQLGRLVVLYDSNDISLDGDLNRSFSESVEDRYKAYGWQVIRVEDGNDIEAI
HHHHHHHHHHHCCEEEEECCCCEEECCCCCCHHHHHHHHHHHHCCEEEEEEECCCCHHHH
AKAIEEAKADEKRPTLIEVRTTIGFGSPNKSGKSASHGSPLGVEETKLTKEAYAWTAEQD
HHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHEECCCCC
FHVAEEVYENFRKTVQDVGETVQAEWNTMLGEYAQAYPELANELQAAMNGLLPEGWEQNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCC
PTYELGSKAATRNSSGAVINAIAESVPSFFGGSADLAGSNKTYMNNEKDFTRDDYSGKNI
CCCCCCCCHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
WYGVREFAMGAAMNGIALHGGLKTYGGTFFVFSDYLRPAIRLAALMQLPVTYVFTHDSIA
HHHHHHHHHHHHCCCEEEECCHHHCCCEEEEHHHHHHHHHHHHHHHHCCEEEEEECCCEE
VGEDGPTHEPIEQLAALRAMPNVSVIRPADGNESVAAWRLALESTNKPTALVLTRQDLPT
ECCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCEEHEEEHHCCCCCEEEEEECCCCCC
LEGAKDDTYEKVAKGAYVVSASKKETADVILLATGSEVSLAVEAQKALAVDGVDASVVSM
CCCCCCHHHHHHHCCEEEEECCCCCCCCEEEEEECCCEEEEEEHHHHHEECCCCCHHCCC
PSMDRFEAQTAEYKESVLPKAVTKRFAIEMGATFGWHRYVGLEGDVLGIDTFGASAPGEK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEECCCCCCCHHH
IMEEYGFTVENVVRKVKEML
HHHHHCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]