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The map label for this gene is schC [H]

Identifier: 218904636

GI number: 218904636

Start: 3347749

End: 3349368

Strand: Reverse

Name: schC [H]

Synonym: BCAH820_3520

Alternate gene names: 218904636

Gene position: 3349368-3347749 (Counterclockwise)

Preceding gene: 218904642

Following gene: 218904635

Centisome position: 63.16

GC content: 37.28

Gene sequence:

>1620_bases
ATGGAATCGAATGATGTACCAGTTTTAATTGTTGGAGGGGGATTATCAGGATTAGCGTCTGCGTTATTCCTTGCAAAACA
TAATATTGAGTACTTACTTATTGAAAGGCATCTGTCTACTGCCATTCATCCGAAAGCAGGTGGAATCACTTTTCGTACGA
TGGAGTTATTTCGAGAATTAGGTTTAGAACAAAGAATTAGATCGGCGGGTAAAACATTAGAAAATTGCCGAGGAAGAATA
GCTGTTCATACAATAGCTGAGGCGAATCAGGAAGAATTGGCACAAATGAGGGCGAATCAGTATGAAAATGATGAAAAGTT
ACTTCAGAAAATAGAAGAGATTAGTCCATCAAAACAAACTGCTTGTTATCAAATTACTTTAGAAGAGATCATGTTACAAG
AAGCGAGAATATTAGGCGGAGAATTATCTTTTTATCATGAATTAGTTTCTTATGAACAAAATGAGCAAGGAGTAATCGCA
ACGATTCGAAATCGTGAAACAGAAAAAGAAAGTGTCATACATTGTGACTATGTAATTGCAGCAGATGGGGCAAAAAGTAA
AATACGTGAGCAGCTAGGGATAAGTGCGGAGGGACGAGGTACAATCGGTGGCTATTATATGAATATTTATTTTGAAGCGG
ATGTAAGTGAGTTTATGCAAGGAGATGCATTTGGTTTTTCTATGGTACTTCATCCGGAAGTTCTCGGTGCACTCATTCCA
GTCGATAACGCAAGAAGGTGGATTTATCATGTATCCTACGATCCATTAAAAGGAGAGCGACCAGAAGATTTCACTATAGA
ACGTTGTAAACAAATTATTCAAACCGCAATTGGAAGCACAAATGTTGAGCCGGAAATAGTAAGTGTTTTACCGTGGAAAG
CGGCTGAAAGTACTGCTACAAAATTTCAAGATAATCGCATTTTTTTAGTTGGTGATTCTGCACATATTATGCCGCCAACA
GGAGGGTTTGGTTCCAATACAGGAATACAAGATGCACACAATCTAGCCTGGAAATTAGCGGCTGTTATAAAAGGAAAGGC
AAAACCAAAACTGTTAGAAACATATCATGAAGAGAGATATCCTGTTGCAAAATTAACGACAGCTTATGCAAGTAGTTTAC
TGTTTCGTGCTGCGAATAGAGAGGAAGGCAGTTTGAATAAGATGGATGGTTTAGCTGTAACTGCTGGGTATCATTATAGT
TCAGATGCAATAATAGATGACGCAGTCACTCCACATAGAATGGATATAGTACAGTTGAACGGAAGACCTGGAACGCGAGC
ACCACATTTTATTGGAATGTATGAGGAGAAAGAAGTCTCTGTCCTTGATTTATTAGGTAACGATTTTGTTTTGCTTACTG
GAGCAGAAAATGATTCTTGGGCTGAATCAGCACATACTGTTTCAGCTAAATTAGGAGTAAATATAAAAGTATATCGCGTT
GGTTTAAGTGGAGATTTTATTGCTCAAGAAAATATTTTTAGCGAATTATATGGTTTAAGTGATGGAGGAGCTGTATTAAT
TAGACCAGATGCTTTTATAGGATGGCGTTCGGAAAAAGAGGTAGTAAATCTAGATGTAGTGCTTGAAGAGGTAATGAGTA
ATTTATTATGTGATTTTTAA

Upstream 100 bases:

>100_bases
TATATGATAATTTAAAATGAAATATAAGTCTATATCTTTGTTGTTTTTTTGATTATATTTATGTCACTGAGCTCAGAACA
ATGATGTGGAGGATAAGTAT

Downstream 100 bases:

>100_bases
GTAACTAAGGAAGTATTGTCTTTTATAGGACGATACTTCTATTTTTTTAGCTTAAAAAATAAAGATTGTGTAGTGAAGAG
ACATTATTATTATAAAAATA

Product: FAD-binding monooxygenase, PheA/TfdB family

Products: H2O; 3-(2,3-dihydroxyphenyl)propionate; NAD [C]

Alternate protein names: NA

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MESNDVPVLIVGGGLSGLASALFLAKHNIEYLLIERHLSTAIHPKAGGITFRTMELFRELGLEQRIRSAGKTLENCRGRI
AVHTIAEANQEELAQMRANQYENDEKLLQKIEEISPSKQTACYQITLEEIMLQEARILGGELSFYHELVSYEQNEQGVIA
TIRNRETEKESVIHCDYVIAADGAKSKIREQLGISAEGRGTIGGYYMNIYFEADVSEFMQGDAFGFSMVLHPEVLGALIP
VDNARRWIYHVSYDPLKGERPEDFTIERCKQIIQTAIGSTNVEPEIVSVLPWKAAESTATKFQDNRIFLVGDSAHIMPPT
GGFGSNTGIQDAHNLAWKLAAVIKGKAKPKLLETYHEERYPVAKLTTAYASSLLFRAANREEGSLNKMDGLAVTAGYHYS
SDAIIDDAVTPHRMDIVQLNGRPGTRAPHFIGMYEEKEVSVLDLLGNDFVLLTGAENDSWAESAHTVSAKLGVNIKVYRV
GLSGDFIAQENIFSELYGLSDGGAVLIRPDAFIGWRSEKEVVNLDVVLEEVMSNLLCDF

Sequences:

>Translated_539_residues
MESNDVPVLIVGGGLSGLASALFLAKHNIEYLLIERHLSTAIHPKAGGITFRTMELFRELGLEQRIRSAGKTLENCRGRI
AVHTIAEANQEELAQMRANQYENDEKLLQKIEEISPSKQTACYQITLEEIMLQEARILGGELSFYHELVSYEQNEQGVIA
TIRNRETEKESVIHCDYVIAADGAKSKIREQLGISAEGRGTIGGYYMNIYFEADVSEFMQGDAFGFSMVLHPEVLGALIP
VDNARRWIYHVSYDPLKGERPEDFTIERCKQIIQTAIGSTNVEPEIVSVLPWKAAESTATKFQDNRIFLVGDSAHIMPPT
GGFGSNTGIQDAHNLAWKLAAVIKGKAKPKLLETYHEERYPVAKLTTAYASSLLFRAANREEGSLNKMDGLAVTAGYHYS
SDAIIDDAVTPHRMDIVQLNGRPGTRAPHFIGMYEEKEVSVLDLLGNDFVLLTGAENDSWAESAHTVSAKLGVNIKVYRV
GLSGDFIAQENIFSELYGLSDGGAVLIRPDAFIGWRSEKEVVNLDVVLEEVMSNLLCDF
>Mature_539_residues
MESNDVPVLIVGGGLSGLASALFLAKHNIEYLLIERHLSTAIHPKAGGITFRTMELFRELGLEQRIRSAGKTLENCRGRI
AVHTIAEANQEELAQMRANQYENDEKLLQKIEEISPSKQTACYQITLEEIMLQEARILGGELSFYHELVSYEQNEQGVIA
TIRNRETEKESVIHCDYVIAADGAKSKIREQLGISAEGRGTIGGYYMNIYFEADVSEFMQGDAFGFSMVLHPEVLGALIP
VDNARRWIYHVSYDPLKGERPEDFTIERCKQIIQTAIGSTNVEPEIVSVLPWKAAESTATKFQDNRIFLVGDSAHIMPPT
GGFGSNTGIQDAHNLAWKLAAVIKGKAKPKLLETYHEERYPVAKLTTAYASSLLFRAANREEGSLNKMDGLAVTAGYHYS
SDAIIDDAVTPHRMDIVQLNGRPGTRAPHFIGMYEEKEVSVLDLLGNDFVLLTGAENDSWAESAHTVSAKLGVNIKVYRV
GLSGDFIAQENIFSELYGLSDGGAVLIRPDAFIGWRSEKEVVNLDVVLEEVMSNLLCDF

Specific function: Involved in developmentally regulated synthesis of a compound biosynthetically related to polyketide antibiotics which is essential for spore color in Streptomyces halstedii [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pheA/tfdB FAD monooxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786543, Length=403, Percent_Identity=25.0620347394541, Blast_Score=102, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.- [C]

Molecular weight: Translated: 59692; Mature: 59692

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESNDVPVLIVGGGLSGLASALFLAKHNIEYLLIERHLSTAIHPKAGGITFRTMELFREL
CCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEEEHHHHHCCCCCCCEEHHHHHHHHHC
GLEQRIRSAGKTLENCRGRIAVHTIAEANQEELAQMRANQYENDEKLLQKIEEISPSKQT
CHHHHHHHHHHHHHHCCCCEEEEEEHHCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
ACYQITLEEIMLQEARILGGELSFYHELVSYEQNEQGVIATIRNRETEKESVIHCDYVIA
EEEEEEHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEEEEEE
ADGAKSKIREQLGISAEGRGTIGGYYMNIYFEADVSEFMQGDAFGFSMVLHPEVLGALIP
CCCCHHHHHHHHCCCCCCCCCCCEEEEEEEEECCHHHHHCCCCCCEEEEECHHHHHHHCC
VDNARRWIYHVSYDPLKGERPEDFTIERCKQIIQTAIGSTNVEPEIVSVLPWKAAESTAT
CCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHH
KFQDNRIFLVGDSAHIMPPTGGFGSNTGIQDAHNLAWKLAAVIKGKAKPKLLETYHEERY
HCCCCEEEEEECCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
PVAKLTTAYASSLLFRAANREEGSLNKMDGLAVTAGYHYSSDAIIDDAVTPHRMDIVQLN
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCEECCCCEECCCCCCCEEEEEEEC
GRPGTRAPHFIGMYEEKEVSVLDLLGNDFVLLTGAENDSWAESAHTVSAKLGVNIKVYRV
CCCCCCCCCEEECCCCCCCEEEEECCCCEEEEECCCCCCHHHHHHEEEEEECCEEEEEEE
GLSGDFIAQENIFSELYGLSDGGAVLIRPDAFIGWRSEKEVVNLDVVLEEVMSNLLCDF
ECCCCCEEHHHHHHHHHCCCCCCEEEECCCCEECCCCCCCEEHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MESNDVPVLIVGGGLSGLASALFLAKHNIEYLLIERHLSTAIHPKAGGITFRTMELFREL
CCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEEEHHHHHCCCCCCCEEHHHHHHHHHC
GLEQRIRSAGKTLENCRGRIAVHTIAEANQEELAQMRANQYENDEKLLQKIEEISPSKQT
CHHHHHHHHHHHHHHCCCCEEEEEEHHCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
ACYQITLEEIMLQEARILGGELSFYHELVSYEQNEQGVIATIRNRETEKESVIHCDYVIA
EEEEEEHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEEEEEE
ADGAKSKIREQLGISAEGRGTIGGYYMNIYFEADVSEFMQGDAFGFSMVLHPEVLGALIP
CCCCHHHHHHHHCCCCCCCCCCCEEEEEEEEECCHHHHHCCCCCCEEEEECHHHHHHHCC
VDNARRWIYHVSYDPLKGERPEDFTIERCKQIIQTAIGSTNVEPEIVSVLPWKAAESTAT
CCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHH
KFQDNRIFLVGDSAHIMPPTGGFGSNTGIQDAHNLAWKLAAVIKGKAKPKLLETYHEERY
HCCCCEEEEEECCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
PVAKLTTAYASSLLFRAANREEGSLNKMDGLAVTAGYHYSSDAIIDDAVTPHRMDIVQLN
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCEECCCCEECCCCCCCEEEEEEEC
GRPGTRAPHFIGMYEEKEVSVLDLLGNDFVLLTGAENDSWAESAHTVSAKLGVNIKVYRV
CCCCCCCCCEEECCCCCCCEEEEECCCCEEEEECCCCCCHHHHHHEEEEEECCEEEEEEE
GLSGDFIAQENIFSELYGLSDGGAVLIRPDAFIGWRSEKEVVNLDVVLEEVMSNLLCDF
ECCCCCEEHHHHHHHHHCCCCCCEEEECCCCEECCCCCCCEEHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 3-(3-hydroxyphenyl)propionate; NADH; O2 [C]

Specific reaction: 3-(3-hydroxyphenyl)propionate + NADH + O2 = H2O + 3-(2,3-dihydroxyphenyl)propionate + NAD [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8253693; 8344517 [H]