Click here to switch to the map view.

The map label for this gene is fhuG [H]

Identifier: 218904606

GI number: 218904606

Start: 3318508

End: 3319524

Strand: Reverse

Name: fhuG [H]

Synonym: BCAH820_3490

Alternate gene names: 218904606

Gene position: 3319524-3318508 (Counterclockwise)

Preceding gene: 218904607

Following gene: 218904605

Centisome position: 62.6

GC content: 38.05

Gene sequence:

>1017_bases
GTGAAGAAGATTTTAAACACAGATAAGAAGAGAGCTATTACTGTAACGACAATATTTGGTTGTATTGGTATCGCTGTCAT
TTTAATTAGTTTAAATACAGGAACATTGAGTATAGCGCCACTTAAAGTAATTCAAACACTTTTCGGTTATGGTGATTTTG
AGAGCGCAACCGTGCTATATGATTATCGTATGCCAAGAATTATAATCACCATGTTAGCTGGCATTGGCCTTGGGATTTCC
GGTGCGATTTTGCAAGGATTATCACGTAATGCACTTGCAGACCCTGGTATTTTAGGATTACATTCCGGTGCGTCTTTCGG
TCTTATCGTATTTGTTACTTTCTTTCATTCTATTAATGAGAATGCATCCATTTTAATACCGTTATTTACATTTGGCGGAG
GAGTATTAGCTGCATTTCTTATTATTTTACTTGCGAGTGATCGGTCAAAAGGTTTACTTCCCATTAGACTTATTCTCGTT
GGTATTGCAGTTTCAGCTGGCTTTAGTGCAATTTCATTATTTTTCTCTCTCAAGTTAAATGATGAGACGTATACATTCGC
TTCTAGATGGCTAGTTGGTAACGTGTGGGGAAGGGACTGGATTCATGTCCTTGCATTATTACCTTGGATTTTCATACTAA
CTCCTTATGCGTGGCTAAAATCTAAAACGTTAAATGCATTTTCACTAGGTGATAGTGTAGCAGCAGGACTAGGTGTTTCT
GTTCAAAAAGAACGGTTACTACTTTTAGCTACAGCGGTTGGATTATCTTGCGGAAGTGTAGCGATGGCAGGAGGGATTGG
TTTTATCGGTTTAGTTGCTCCGCATATCGCAAGGAAGTTAGTAGGTACTACATATCAACACTTCCTTCCTTTAGCTGGCA
TTATCGGAATGATTATTTTAGTGCTAGCAGATACGATAGGTCGTTCTATATTTGAGCCAAACTCTATTCCAGCTGGTGTA
GTAGTGGCAGCTTTAGGAGCACCGTATTTTCTTTATTTACTTACAAAAACAAAATAA

Upstream 100 bases:

>100_bases
AGTAAACCCTCCTAAAGAACTTGCGATAGGGATTATGGTAGCTCTCATTGGAGTTCCGTTTTTCCTATATATAGCACGTA
AAGTTGGGAGGGAACTATAA

Downstream 100 bases:

>100_bases
ATACTTCAAAGAGGAGAACATATGAAAAAGAAACTTACTATTTTATTTAGCATCGTGTGTATTTTAGTACTAGCAGCATG
CGGTCAAACGAAAGCTAATA

Product: iron compound ABC transporter, permease protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein G; Ferrichrome transport system permease protein fhuG; Iron(III)-hydroxamate import system permease protein fhuG [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKKILNTDKKRAITVTTIFGCIGIAVILISLNTGTLSIAPLKVIQTLFGYGDFESATVLYDYRMPRIIITMLAGIGLGIS
GAILQGLSRNALADPGILGLHSGASFGLIVFVTFFHSINENASILIPLFTFGGGVLAAFLIILLASDRSKGLLPIRLILV
GIAVSAGFSAISLFFSLKLNDETYTFASRWLVGNVWGRDWIHVLALLPWIFILTPYAWLKSKTLNAFSLGDSVAAGLGVS
VQKERLLLLATAVGLSCGSVAMAGGIGFIGLVAPHIARKLVGTTYQHFLPLAGIIGMIILVLADTIGRSIFEPNSIPAGV
VVAALGAPYFLYLLTKTK

Sequences:

>Translated_338_residues
MKKILNTDKKRAITVTTIFGCIGIAVILISLNTGTLSIAPLKVIQTLFGYGDFESATVLYDYRMPRIIITMLAGIGLGIS
GAILQGLSRNALADPGILGLHSGASFGLIVFVTFFHSINENASILIPLFTFGGGVLAAFLIILLASDRSKGLLPIRLILV
GIAVSAGFSAISLFFSLKLNDETYTFASRWLVGNVWGRDWIHVLALLPWIFILTPYAWLKSKTLNAFSLGDSVAAGLGVS
VQKERLLLLATAVGLSCGSVAMAGGIGFIGLVAPHIARKLVGTTYQHFLPLAGIIGMIILVLADTIGRSIFEPNSIPAGV
VVAALGAPYFLYLLTKTK
>Mature_338_residues
MKKILNTDKKRAITVTTIFGCIGIAVILISLNTGTLSIAPLKVIQTLFGYGDFESATVLYDYRMPRIIITMLAGIGLGIS
GAILQGLSRNALADPGILGLHSGASFGLIVFVTFFHSINENASILIPLFTFGGGVLAAFLIILLASDRSKGLLPIRLILV
GIAVSAGFSAISLFFSLKLNDETYTFASRWLVGNVWGRDWIHVLALLPWIFILTPYAWLKSKTLNAFSLGDSVAAGLGVS
VQKERLLLLATAVGLSCGSVAMAGGIGFIGLVAPHIARKLVGTTYQHFLPLAGIIGMIILVLADTIGRSIFEPNSIPAGV
VVAALGAPYFLYLLTKTK

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=311, Percent_Identity=33.7620578778135, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI1786804, Length=308, Percent_Identity=34.7402597402597, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1786805, Length=312, Percent_Identity=34.9358974358974, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1786347, Length=288, Percent_Identity=31.25, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1788004, Length=289, Percent_Identity=35.2941176470588, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1790741, Length=300, Percent_Identity=31.6666666666667, Blast_Score=109, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35835; Mature: 35835

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILNTDKKRAITVTTIFGCIGIAVILISLNTGTLSIAPLKVIQTLFGYGDFESATVLY
CCCCCCCCCCCEEEHHHHHHHHHHHHHHEECCCCCEEEHHHHHHHHHHCCCCCCCEEEEE
DYRMPRIIITMLAGIGLGISGAILQGLSRNALADPGILGLHSGASFGLIVFVTFFHSINE
ECCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCC
NASILIPLFTFGGGVLAAFLIILLASDRSKGLLPIRLILVGIAVSAGFSAISLFFSLKLN
CCEEEEEHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHEEEEEEEEEC
DETYTFASRWLVGNVWGRDWIHVLALLPWIFILTPYAWLKSKTLNAFSLGDSVAAGLGVS
CCCHHHHHHHHEECCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHCCCHHHHCCCCC
VQKERLLLLATAVGLSCGSVAMAGGIGFIGLVAPHIARKLVGTTYQHFLPLAGIIGMIIL
CCHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLADTIGRSIFEPNSIPAGVVVAALGAPYFLYLLTKTK
HHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEEEECCC
>Mature Secondary Structure
MKKILNTDKKRAITVTTIFGCIGIAVILISLNTGTLSIAPLKVIQTLFGYGDFESATVLY
CCCCCCCCCCCEEEHHHHHHHHHHHHHHEECCCCCEEEHHHHHHHHHHCCCCCCCEEEEE
DYRMPRIIITMLAGIGLGISGAILQGLSRNALADPGILGLHSGASFGLIVFVTFFHSINE
ECCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCC
NASILIPLFTFGGGVLAAFLIILLASDRSKGLLPIRLILVGIAVSAGFSAISLFFSLKLN
CCEEEEEHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHEEEEEEEEEC
DETYTFASRWLVGNVWGRDWIHVLALLPWIFILTPYAWLKSKTLNAFSLGDSVAAGLGVS
CCCHHHHHHHHEECCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHCCCHHHHCCCCC
VQKERLLLLATAVGLSCGSVAMAGGIGFIGLVAPHIARKLVGTTYQHFLPLAGIIGMIIL
CCHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLADTIGRSIFEPNSIPAGVVVAALGAPYFLYLLTKTK
HHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]