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The map label for this gene is nsr [H]

Identifier: 218904586

GI number: 218904586

Start: 3302828

End: 3303520

Strand: Reverse

Name: nsr [H]

Synonym: BCAH820_3470

Alternate gene names: 218904586

Gene position: 3303520-3302828 (Counterclockwise)

Preceding gene: 218904590

Following gene: 218904585

Centisome position: 62.3

GC content: 31.75

Gene sequence:

>693_bases
ATGAAGAAAGTATGTAATTCTATTAAATTAGCAGAGTATATGAAACAAAATAATATTGATTCGTTTTTTAGTAATGATAT
GCAGCCGTATATGGAACTTATATTTTTTAAAAAGAATGAGTTTATTTGTAGAGAAAATGAAGAAATAGACTATTTATATT
TCTTTGTAGAAGGAAAAGCGAAAGCGTTTAACACATTAAGTAACGGGAAATCTGTATTATTATGCTTTTATGATAGCTTG
CAGTTACTTGGAGATGTGGAGTTAATTCATTCACAAAGGATTACTTCAAACGTACAAGTGATGGCAGATTCATATTGTGT
TGGTTTGCCTTTAGGGAAAGTGAGAAATCAACTATTTCATGATGCAAAATTTTTACGATGTATTTGCGGATCATTAGCAC
ATAAGTTAAATCGACTTTCCAAAAATAGTACAATTAATTTACTATATCCGCTTGAAAATAGACTTGCGAGCTACATGTTA
GCGGCAGGAGAAAGAGCAGCTCAGCATGGAAATCGAATTGTGTTTAGTGGAAATTTAACGGAAACAGCTGAATTGTTAGG
AACGAGTTATCGACATTTATTGCGCACGCTGAACACCTTTTGTGATAAAGAGATAATCAAGAAAAACAATGGTTGTTTTG
AAGTGGTAAATGTAAAAGTTTTGAGAGAATTGGCGGCAGATGTTTATAAATAA

Upstream 100 bases:

>100_bases
TGACTGTATCATGCTGAAATTGTGTATTACTATGACATATGTCATAGTGGAAGAAGAAAATTTTGATTACAATGGGGATG
AGTTGTAAAGGTGGGGGATT

Downstream 100 bases:

>100_bases
TATAGTAAAGTGGGGGTTTAGATGAAAATAGCAATCATTTCAGATGTTCATGGAAATAGTCACGCTTTACAAGCAGTATT
AAAAGATTTGGAACATCGCA

Product: cyclic nucleotide-binding domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MKKVCNSIKLAEYMKQNNIDSFFSNDMQPYMELIFFKKNEFICRENEEIDYLYFFVEGKAKAFNTLSNGKSVLLCFYDSL
QLLGDVELIHSQRITSNVQVMADSYCVGLPLGKVRNQLFHDAKFLRCICGSLAHKLNRLSKNSTINLLYPLENRLASYML
AAGERAAQHGNRIVFSGNLTETAELLGTSYRHLLRTLNTFCDKEIIKKNNGCFEVVNVKVLRELAADVYK

Sequences:

>Translated_230_residues
MKKVCNSIKLAEYMKQNNIDSFFSNDMQPYMELIFFKKNEFICRENEEIDYLYFFVEGKAKAFNTLSNGKSVLLCFYDSL
QLLGDVELIHSQRITSNVQVMADSYCVGLPLGKVRNQLFHDAKFLRCICGSLAHKLNRLSKNSTINLLYPLENRLASYML
AAGERAAQHGNRIVFSGNLTETAELLGTSYRHLLRTLNTFCDKEIIKKNNGCFEVVNVKVLRELAADVYK
>Mature_230_residues
MKKVCNSIKLAEYMKQNNIDSFFSNDMQPYMELIFFKKNEFICRENEEIDYLYFFVEGKAKAFNTLSNGKSVLLCFYDSL
QLLGDVELIHSQRITSNVQVMADSYCVGLPLGKVRNQLFHDAKFLRCICGSLAHKLNRLSKNSTINLLYPLENRLASYML
AAGERAAQHGNRIVFSGNLTETAELLGTSYRHLLRTLNTFCDKEIIKKNNGCFEVVNVKVLRELAADVYK

Specific function: Transcription regulator involved in mid-term, stationary-phase viability under nitrogen starvation. Might control expression of the salvage pathways or in some other way repress the recycling of nucleobases to nucleic acids and enhance their use as genera

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788487, Length=215, Percent_Identity=30.6976744186047, Blast_Score=112, Evalue=3e-26,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR012318
- InterPro:   IPR014710 [H]

Pfam domain/function: PF00027 cNMP_binding [H]

EC number: NA

Molecular weight: Translated: 26355; Mature: 26355

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVCNSIKLAEYMKQNNIDSFFSNDMQPYMELIFFKKNEFICRENEEIDYLYFFVEGKA
CCHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHCCCCEEECCCCCCEEEEEEEECCH
KAFNTLSNGKSVLLCFYDSLQLLGDVELIHSQRITSNVQVMADSYCVGLPLGKVRNQLFH
HHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCHHEEECCEEECCCHHHHHHHHHH
DAKFLRCICGSLAHKLNRLSKNSTINLLYPLENRLASYMLAAGERAAQHGNRIVFSGNLT
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCEEEEECCCH
ETAELLGTSYRHLLRTLNTFCDKEIIKKNNGCFEVVNVKVLRELAADVYK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKVCNSIKLAEYMKQNNIDSFFSNDMQPYMELIFFKKNEFICRENEEIDYLYFFVEGKA
CCHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHCCCCEEECCCCCCEEEEEEEECCH
KAFNTLSNGKSVLLCFYDSLQLLGDVELIHSQRITSNVQVMADSYCVGLPLGKVRNQLFH
HHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCHHEEECCEEECCCHHHHHHHHHH
DAKFLRCICGSLAHKLNRLSKNSTINLLYPLENRLASYMLAAGERAAQHGNRIVFSGNLT
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCEEEEECCCH
ETAELLGTSYRHLLRTLNTFCDKEIIKKNNGCFEVVNVKVLRELAADVYK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]