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The map label for this gene is gmuR [H]

Identifier: 218904540

GI number: 218904540

Start: 3263074

End: 3263811

Strand: Reverse

Name: gmuR [H]

Synonym: BCAH820_3424

Alternate gene names: 218904540

Gene position: 3263811-3263074 (Counterclockwise)

Preceding gene: 218904541

Following gene: 218904538

Centisome position: 61.55

GC content: 38.75

Gene sequence:

>738_bases
ATGGCAAGCGGATCAACACAAGTAAAATACCTCGGTATTTATCAAAAAATGAAGCAGCAAATTTTAGACGGCGAATATAA
AATTAATGAAAAAATTCCAAGTAGCCCCGTCCTTGCTGAAGAATTTGGTGTTTCTGTCCTTACCATAAAAAAAGCGCTGG
ATCTATTAGTTAGAGACGGTTACATCATTCGCCGGCGCGGAAGTGGAACAGTCGTTCAAGATTGGCGTCAGCAGGAAAAA
GCACGAATGATTCAAACTTTAACAGGTACAAAAGCTGTTTATGGCAGCGAGGTAGAAAGTAAAATTATTGAGTTTACGAT
TGTCGGTGCCGATGAAATTATTGCTGAAAAATTGGGCATTTCAGTAGGAGATTTTGTATATAAAATCATCCGCCTCCGCA
TCATTCACAGTATTCCAACGATTATGGAGCATACATGGATGCCTATTTCGGTCATACCGGGTGTTGAAGTTTCAGTTTTA
GAGGAGTCGATCTACTCGCACATTCAAAATAAACTTGGTCTTGAAGTGGGAACATCCGTTGTTAGGGTCAAAGGAGTTCG
TCCAGATGATAGGGAAAAGCAATTTATGAACTTAACAAATCAAGATTTCTTAATGAGAGTTGAACAAGTGGCCTACTTAA
CGGATGGACGAACTTTTGAATACTCTTATGCTGATCACCTGCCAGAAACCTTTGAATTTGAAACAGTTATTACTGCAAAA
AGTTATAAAGAGGCATAA

Upstream 100 bases:

>100_bases
TAGAAAACGGATTTGCTGCACCTTCACCTTCAGTTTATAAACTTGAGGCTTTAAACTTGAATGAATAGAAGAGGGAATAC
AGCATAAAGGAGGTATAGAA

Downstream 100 bases:

>100_bases
AAAATAGGTTGAGGCGCGTATTGCCTCAACCTATTTTTTGTCTTCAATATAGTAGAAACAGCTATTATTCATCGGCTGTA
ATAAGCATGGATGTGTTCCC

Product: transcriptional regulator, GntR family

Products: NA

Alternate protein names: Glucomannan utilization operon repressor; Glucomannan utilization protein R [H]

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MASGSTQVKYLGIYQKMKQQILDGEYKINEKIPSSPVLAEEFGVSVLTIKKALDLLVRDGYIIRRRGSGTVVQDWRQQEK
ARMIQTLTGTKAVYGSEVESKIIEFTIVGADEIIAEKLGISVGDFVYKIIRLRIIHSIPTIMEHTWMPISVIPGVEVSVL
EESIYSHIQNKLGLEVGTSVVRVKGVRPDDREKQFMNLTNQDFLMRVEQVAYLTDGRTFEYSYADHLPETFEFETVITAK
SYKEA

Sequences:

>Translated_245_residues
MASGSTQVKYLGIYQKMKQQILDGEYKINEKIPSSPVLAEEFGVSVLTIKKALDLLVRDGYIIRRRGSGTVVQDWRQQEK
ARMIQTLTGTKAVYGSEVESKIIEFTIVGADEIIAEKLGISVGDFVYKIIRLRIIHSIPTIMEHTWMPISVIPGVEVSVL
EESIYSHIQNKLGLEVGTSVVRVKGVRPDDREKQFMNLTNQDFLMRVEQVAYLTDGRTFEYSYADHLPETFEFETVITAK
SYKEA
>Mature_244_residues
ASGSTQVKYLGIYQKMKQQILDGEYKINEKIPSSPVLAEEFGVSVLTIKKALDLLVRDGYIIRRRGSGTVVQDWRQQEKA
RMIQTLTGTKAVYGSEVESKIIEFTIVGADEIIAEKLGISVGDFVYKIIRLRIIHSIPTIMEHTWMPISVIPGVEVSVLE
ESIYSHIQNKLGLEVGTSVVRVKGVRPDDREKQFMNLTNQDFLMRVEQVAYLTDGRTFEYSYADHLPETFEFETVITAKS
YKEA

Specific function: Transcriptional repressor of the gmuBACDREFG operon which is involved in the uptake and degradation of glucomannan [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=234, Percent_Identity=26.4957264957265, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790118, Length=218, Percent_Identity=29.8165137614679, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI87082252, Length=173, Percent_Identity=29.4797687861272, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1790540, Length=225, Percent_Identity=24.4444444444444, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27801; Mature: 27670

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASGSTQVKYLGIYQKMKQQILDGEYKINEKIPSSPVLAEEFGVSVLTIKKALDLLVRDG
CCCCCCEEHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCC
YIIRRRGSGTVVQDWRQQEKARMIQTLTGTKAVYGSEVESKIIEFTIVGADEIIAEKLGI
EEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHEEEEEEECHHHHHHHHHCC
SVGDFVYKIIRLRIIHSIPTIMEHTWMPISVIPGVEVSVLEESIYSHIQNKLGLEVGTSV
CHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHCHHHCCCE
VRVKGVRPDDREKQFMNLTNQDFLMRVEQVAYLTDGRTFEYSYADHLPETFEFETVITAK
EEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEHHHCCCCCEEHEEEEECC
SYKEA
CCCCC
>Mature Secondary Structure 
ASGSTQVKYLGIYQKMKQQILDGEYKINEKIPSSPVLAEEFGVSVLTIKKALDLLVRDG
CCCCCEEHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCC
YIIRRRGSGTVVQDWRQQEKARMIQTLTGTKAVYGSEVESKIIEFTIVGADEIIAEKLGI
EEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHEEEEEEECHHHHHHHHHCC
SVGDFVYKIIRLRIIHSIPTIMEHTWMPISVIPGVEVSVLEESIYSHIQNKLGLEVGTSV
CHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHCHHHCCCE
VRVKGVRPDDREKQFMNLTNQDFLMRVEQVAYLTDGRTFEYSYADHLPETFEFETVITAK
EEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEHHHCCCCCEEHEEEEECC
SYKEA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]