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The map label for this gene is ntdC [H]

Identifier: 218904387

GI number: 218904387

Start: 3114036

End: 3115085

Strand: Reverse

Name: ntdC [H]

Synonym: BCAH820_3271

Alternate gene names: 218904387

Gene position: 3115085-3114036 (Counterclockwise)

Preceding gene: 218904388

Following gene: 218904386

Centisome position: 58.75

GC content: 32.48

Gene sequence:

>1050_bases
ATGAATATTGGAATTATAGGTGCAGGAAGTATTGCAAGAGCTCATTCTAGAGCATTATCAACTATTGATAATTGTAAATT
AGTTGGAGTGTATGATGTTAATTCTGAGAATGCCGATAAATTGGTAGGGGATTTTGGTGGGAAGGTTTTTGATAGCTATG
AAGAGTTACTAGAAGTAGTTGATGGGGTAATAATATCTTCCCCGAATTTTTGTCATAAATCTCAAGCTGTTCAAGCATTA
TTAACAAACAAACATGTGTTATGTGAAAAGCCTATGGCGATCTCTTGTGAGGAAGCAAAGTACATGATGACAATAGCGAA
AAATACTAATTTAGTCGCTTCAATGGGGTTTAATTATCGCTACTTATCCTATGTTAAGGCTTTAAAGCAATTAATTCAAA
ATGAAGAATTAGGGGAAATAGTAGTAATAAGATTGCATTTTAAAAAAAATAGCGCTTTTAGGAGAACTTCGTTTACTTGG
CGAGATGATTTTCAAAGTAATAGAACTAGTGGAGCCTTGGGAGATTTGGGAATTCATCTAATAGATTTACTATGGTTTTT
ATTTGAGAGTGATTTTAGAGAGGATACCGTTCGAACTAAAATCAAAACAAATGTTAAGGAAAAAGAAAGCAAACCAGTTT
TTGTTGATGACTATGCTGAGGTTTATGGCCAATTGGAAAATAAGGTTTTTATTAATATTACAACATCTAAAAGTTCATTT
CCAGATGATTGTGGTTTTAGTATAGAGGTAATAGGTACGAAAAAAGAATATAAGTATTCTTCTAAAGAGCCAAATAAATA
TATACTCTTTGATGGATTGGAAAAACATGAAATCGCATTACCATTACCTTTACTAGTCGATCCAGAAAACGAGATTTTTG
AATGGTCTGATTCTTTTAGAAGTGAAATTTTAGAATGGGCAAAGGCTGCGGAAGATGGTCCTAAAAAGTCTGTAGCAACA
TTTGAAGATGGATTTCGTTCACAAGTTATTTTGGATATGTTTTTTGATAAAAGCAGTAGTAATAAAGAGCGATCTGTAGC
AACTATTTAG

Upstream 100 bases:

>100_bases
AGGCTAAAAAAATACACTCAATGTTAGCTCAAGGTGAATACTCGATTGGAATTTTAAATACTCTAAAGCACATTATTAAT
TAAAAGGAGATGTTCATATA

Downstream 100 bases:

>100_bases
TTTTATGGTAAAAACAGGGGTTTAGAACTTTTACTTAAATCCCTGTTTTTATTTTGGATTGGAGTTGAGAAAAGATGCGG
TTAATGTTTTATTATGGTTG

Product: oxidoreductase, Gfo/Idh/MocA family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MNIGIIGAGSIARAHSRALSTIDNCKLVGVYDVNSENADKLVGDFGGKVFDSYEELLEVVDGVIISSPNFCHKSQAVQAL
LTNKHVLCEKPMAISCEEAKYMMTIAKNTNLVASMGFNYRYLSYVKALKQLIQNEELGEIVVIRLHFKKNSAFRRTSFTW
RDDFQSNRTSGALGDLGIHLIDLLWFLFESDFREDTVRTKIKTNVKEKESKPVFVDDYAEVYGQLENKVFINITTSKSSF
PDDCGFSIEVIGTKKEYKYSSKEPNKYILFDGLEKHEIALPLPLLVDPENEIFEWSDSFRSEILEWAKAAEDGPKKSVAT
FEDGFRSQVILDMFFDKSSSNKERSVATI

Sequences:

>Translated_349_residues
MNIGIIGAGSIARAHSRALSTIDNCKLVGVYDVNSENADKLVGDFGGKVFDSYEELLEVVDGVIISSPNFCHKSQAVQAL
LTNKHVLCEKPMAISCEEAKYMMTIAKNTNLVASMGFNYRYLSYVKALKQLIQNEELGEIVVIRLHFKKNSAFRRTSFTW
RDDFQSNRTSGALGDLGIHLIDLLWFLFESDFREDTVRTKIKTNVKEKESKPVFVDDYAEVYGQLENKVFINITTSKSSF
PDDCGFSIEVIGTKKEYKYSSKEPNKYILFDGLEKHEIALPLPLLVDPENEIFEWSDSFRSEILEWAKAAEDGPKKSVAT
FEDGFRSQVILDMFFDKSSSNKERSVATI
>Mature_349_residues
MNIGIIGAGSIARAHSRALSTIDNCKLVGVYDVNSENADKLVGDFGGKVFDSYEELLEVVDGVIISSPNFCHKSQAVQAL
LTNKHVLCEKPMAISCEEAKYMMTIAKNTNLVASMGFNYRYLSYVKALKQLIQNEELGEIVVIRLHFKKNSAFRRTSFTW
RDDFQSNRTSGALGDLGIHLIDLLWFLFESDFREDTVRTKIKTNVKEKESKPVFVDDYAEVYGQLENKVFINITTSKSSF
PDDCGFSIEVIGTKKEYKYSSKEPNKYILFDGLEKHEIALPLPLLVDPENEIFEWSDSFRSEILEWAKAAEDGPKKSVAT
FEDGFRSQVILDMFFDKSSSNKERSVATI

Specific function: Part of the ntdABC operon that biosynthesizes the NTD (3,3'-neotrehalosadiamine) antibiotic [H]

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI1787574, Length=194, Percent_Identity=30.4123711340206, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI87082405, Length=191, Percent_Identity=27.7486910994764, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87081947, Length=130, Percent_Identity=33.0769230769231, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323975, Length=258, Percent_Identity=27.906976744186, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 39482; Mature: 39482

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIGIIGAGSIARAHSRALSTIDNCKLVGVYDVNSENADKLVGDFGGKVFDSYEELLEVV
CCEEEEECCHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHH
DGVIISSPNFCHKSQAVQALLTNKHVLCEKPMAISCEEAKYMMTIAKNTNLVASMGFNYR
CCEEECCCCCHHHHHHHHHHHHCCCEEECCCCEEECCCCEEEEEEECCCCEEEECCCCHH
YLSYVKALKQLIQNEELGEIVVIRLHFKKNSAFRRTSFTWRDDFQSNRTSGALGDLGIHL
HHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEECCCCCHHHHCCCCCCCCHHHHHHHH
IDLLWFLFESDFREDTVRTKIKTNVKEKESKPVFVDDYAEVYGQLENKVFINITTSKSSF
HHHHHHHHHCCCHHHHHHHHHHCCCHHHCCCCEEEECHHHHHHHCCCEEEEEEEECCCCC
PDDCGFSIEVIGTKKEYKYSSKEPNKYILFDGLEKHEIALPLPLLVDPENEIFEWSDSFR
CCCCCCEEEEEECCHHCCCCCCCCCEEEEECCCCCCCEEECCCEEECCCHHHHHHHHHHH
SEILEWAKAAEDGPKKSVATFEDGFRSQVILDMFFDKSSSNKERSVATI
HHHHHHHHHCCCCCCCCHHHHHHCCHHHEEEHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNIGIIGAGSIARAHSRALSTIDNCKLVGVYDVNSENADKLVGDFGGKVFDSYEELLEVV
CCEEEEECCHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHH
DGVIISSPNFCHKSQAVQALLTNKHVLCEKPMAISCEEAKYMMTIAKNTNLVASMGFNYR
CCEEECCCCCHHHHHHHHHHHHCCCEEECCCCEEECCCCEEEEEEECCCCEEEECCCCHH
YLSYVKALKQLIQNEELGEIVVIRLHFKKNSAFRRTSFTWRDDFQSNRTSGALGDLGIHL
HHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEECCCCCHHHHCCCCCCCCHHHHHHHH
IDLLWFLFESDFREDTVRTKIKTNVKEKESKPVFVDDYAEVYGQLENKVFINITTSKSSF
HHHHHHHHHCCCHHHHHHHHHHCCCHHHCCCCEEEECHHHHHHHCCCEEEEEEEECCCCC
PDDCGFSIEVIGTKKEYKYSSKEPNKYILFDGLEKHEIALPLPLLVDPENEIFEWSDSFR
CCCCCCEEEEEECCHHCCCCCCCCCEEEEECCCCCCCEEECCCEEECCCHHHHHHHHHHH
SEILEWAKAAEDGPKKSVATFEDGFRSQVILDMFFDKSSSNKERSVATI
HHHHHHHHHCCCCCCCCHHHHHHCCHHHEEEHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]