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The map label for this gene is benK [H]

Identifier: 218904168

GI number: 218904168

Start: 2893182

End: 2894540

Strand: Reverse

Name: benK [H]

Synonym: BCAH820_3052

Alternate gene names: 218904168

Gene position: 2894540-2893182 (Counterclockwise)

Preceding gene: 218904170

Following gene: 218904167

Centisome position: 54.59

GC content: 37.09

Gene sequence:

>1359_bases
ATGAAATCGATTAACCCAATGAATGTAATAGATGAGAGTCGTATTCATTCCATGCACCTTTGGTTAATATTTTGGCTATT
TATCGTAATTGCATTTGATGGATATGATGTTGTTATTTATGGAGCAGCTGTACCGTCGCTCATTAAAGAGTGGGGGATAT
CAGATGTTACAGCAGGGGCAATTGGTAGTTATACAGTTATAGGAACGGCAATTGGTGCTATTTTCTTCGGTCTAGTAGCT
GATAAAATTGGTCGTAAAAATATTATACTGTTAACTACAATCTTATTTAGCTTATTTACATTTCTATCTGGTTTTGCGAA
TGATCCTGTTACATTTACAATCTTTCGTGTCATCGCTGGTATTGGGCTTGGTGGAGTGATGCCGAATGTAATTGCAATAG
CTACTGAATTTTCTCCGAAACGAGTTCGAACTGCTATTGTATCTTTTATTTTTTGTGGATATTCAGTTGGGGCAATGGCA
GCAGCACTTACAAGTCGATCACTTCTCATGACAGCAGGATGGAAACCAGTCTTTTGGTTAGCGGGACTTCCGTTATTGTT
TCTTCCATTTTTAATAAAAAGTATTCCAGAGTCTGTTAGTTTTCTTTTAGGGAAAGGAAAAATAGAAGAAGCTAAAAAAG
TGATAGCGAAAGTAAATCCGAAATTAGGTGAATATGCGACAATTGAATTTACAAAACCACCAACGAAAGAAGCTGGTTCT
CCAGTTGTTAAGTTATTTGAGGAAAAACGCGCTATAAGTACGATTATGTTTTGGATTTCATGTTTTAGTGCTTTCGTGCT
CATTTACTCTATGAATACATGGCTGCCGCGACTTATGATGCAGTCAGGATACGATTTGAAATCAAGTCTTTCATTTACAG
CTGTCATGCAGATTGGTGCTATCGTTGGAACGCTCATCTTCGGTCCAATCGTGGATAAAGTTGGATTTAAAAAGGTACTT
GTTCCATTATTTTTCTGTGGAGCAATTGCGTTATCACTCATCGGATTTGCAAATAGTATGTTTGTTGGATTTTTGTTAAT
TGCTATAATTGGTGCTTCTTCAGTTGGACTACAAAATATGTCAAATGCATTTGTTTCTCAATACTATCCTAGTAATATGC
GTTCAACAGCGGTAGGAAGTACAATGGCATTTGGGCGTCTTGGAGGTGTGGTCGCGCCGACCTTTGTAGGTGTATTACTT
TCTATGCATTTCTTACCTCAATATAACTTTTCAGCTATTGCGAGCGCTGCTGTAATTGGTGGTATAGCAATGCTGTTTGT
GAAAGAGGAACATGGAATTTATTATAAAGAGAAAAAAGAGATAGTAAGCGGAGATAGTAACGTAACTACAGCAAAATAA

Upstream 100 bases:

>100_bases
ATTCAGAAAGGTTTTTAGAAAAGTAGAAAGGGATAGTTGAAAGCGTTTACTATTTTGGAGGCTGAGAAAAGGAAAATCCC
CATATAAGGAGGTTATTAAG

Downstream 100 bases:

>100_bases
TAAACAATTAATCCCGGGGATATATTTCTTCGGGATTTCAAATTGCTTGCTTAATAATTTAAATATTTAGTTTTATTTTA
TGTAACGCTTCTTATACAAT

Product: benzoate MFS transporter

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MKSINPMNVIDESRIHSMHLWLIFWLFIVIAFDGYDVVIYGAAVPSLIKEWGISDVTAGAIGSYTVIGTAIGAIFFGLVA
DKIGRKNIILLTTILFSLFTFLSGFANDPVTFTIFRVIAGIGLGGVMPNVIAIATEFSPKRVRTAIVSFIFCGYSVGAMA
AALTSRSLLMTAGWKPVFWLAGLPLLFLPFLIKSIPESVSFLLGKGKIEEAKKVIAKVNPKLGEYATIEFTKPPTKEAGS
PVVKLFEEKRAISTIMFWISCFSAFVLIYSMNTWLPRLMMQSGYDLKSSLSFTAVMQIGAIVGTLIFGPIVDKVGFKKVL
VPLFFCGAIALSLIGFANSMFVGFLLIAIIGASSVGLQNMSNAFVSQYYPSNMRSTAVGSTMAFGRLGGVVAPTFVGVLL
SMHFLPQYNFSAIASAAVIGGIAMLFVKEEHGIYYKEKKEIVSGDSNVTTAK

Sequences:

>Translated_452_residues
MKSINPMNVIDESRIHSMHLWLIFWLFIVIAFDGYDVVIYGAAVPSLIKEWGISDVTAGAIGSYTVIGTAIGAIFFGLVA
DKIGRKNIILLTTILFSLFTFLSGFANDPVTFTIFRVIAGIGLGGVMPNVIAIATEFSPKRVRTAIVSFIFCGYSVGAMA
AALTSRSLLMTAGWKPVFWLAGLPLLFLPFLIKSIPESVSFLLGKGKIEEAKKVIAKVNPKLGEYATIEFTKPPTKEAGS
PVVKLFEEKRAISTIMFWISCFSAFVLIYSMNTWLPRLMMQSGYDLKSSLSFTAVMQIGAIVGTLIFGPIVDKVGFKKVL
VPLFFCGAIALSLIGFANSMFVGFLLIAIIGASSVGLQNMSNAFVSQYYPSNMRSTAVGSTMAFGRLGGVVAPTFVGVLL
SMHFLPQYNFSAIASAAVIGGIAMLFVKEEHGIYYKEKKEIVSGDSNVTTAK
>Mature_452_residues
MKSINPMNVIDESRIHSMHLWLIFWLFIVIAFDGYDVVIYGAAVPSLIKEWGISDVTAGAIGSYTVIGTAIGAIFFGLVA
DKIGRKNIILLTTILFSLFTFLSGFANDPVTFTIFRVIAGIGLGGVMPNVIAIATEFSPKRVRTAIVSFIFCGYSVGAMA
AALTSRSLLMTAGWKPVFWLAGLPLLFLPFLIKSIPESVSFLLGKGKIEEAKKVIAKVNPKLGEYATIEFTKPPTKEAGS
PVVKLFEEKRAISTIMFWISCFSAFVLIYSMNTWLPRLMMQSGYDLKSSLSFTAVMQIGAIVGTLIFGPIVDKVGFKKVL
VPLFFCGAIALSLIGFANSMFVGFLLIAIIGASSVGLQNMSNAFVSQYYPSNMRSTAVGSTMAFGRLGGVVAPTFVGVLL
SMHFLPQYNFSAIASAAVIGGIAMLFVKEEHGIYYKEKKEIVSGDSNVTTAK

Specific function: Probable uptake of benzoate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI7662270, Length=226, Percent_Identity=27.8761061946903, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI216548223, Length=219, Percent_Identity=29.2237442922374, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI213021148, Length=412, Percent_Identity=24.2718446601942, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI24308167, Length=394, Percent_Identity=21.3197969543147, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI31542327, Length=386, Percent_Identity=25.3886010362694, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI24497490, Length=388, Percent_Identity=25, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI73695465, Length=210, Percent_Identity=28.0952380952381, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI166064021, Length=393, Percent_Identity=22.1374045801527, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI262399383, Length=167, Percent_Identity=28.7425149700599, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI4507005, Length=405, Percent_Identity=22.2222222222222, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87081723, Length=379, Percent_Identity=29.287598944591, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI87082404, Length=398, Percent_Identity=27.3869346733668, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1786229, Length=444, Percent_Identity=23.4234234234234, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI87082231, Length=407, Percent_Identity=24.8157248157248, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI87082159, Length=368, Percent_Identity=26.3586956521739, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1788074, Length=428, Percent_Identity=25.9345794392523, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1788068, Length=368, Percent_Identity=25, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1790463, Length=335, Percent_Identity=25.0746268656716, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1790550, Length=395, Percent_Identity=21.7721518987342, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789207, Length=313, Percent_Identity=23.0031948881789, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1789312, Length=313, Percent_Identity=21.7252396166134, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32564663, Length=386, Percent_Identity=24.0932642487047, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17565978, Length=367, Percent_Identity=26.7029972752044, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71980582, Length=386, Percent_Identity=24.8704663212435, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71980584, Length=386, Percent_Identity=24.8704663212435, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17565976, Length=322, Percent_Identity=23.9130434782609, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323653, Length=340, Percent_Identity=25.8823529411765, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24640198, Length=204, Percent_Identity=27.9411764705882, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24640196, Length=204, Percent_Identity=27.9411764705882, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24640200, Length=204, Percent_Identity=27.9411764705882, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19922874, Length=411, Percent_Identity=19.2214111922141, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24648211, Length=231, Percent_Identity=25.1082251082251, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356505, Length=213, Percent_Identity=29.1079812206573, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221457686, Length=177, Percent_Identity=30.5084745762712, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24668440, Length=404, Percent_Identity=24.009900990099, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI62484254, Length=397, Percent_Identity=23.1738035264484, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48834; Mature: 48834

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSINPMNVIDESRIHSMHLWLIFWLFIVIAFDGYDVVIYGAAVPSLIKEWGISDVTAGA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHCCCCCCCCCC
IGSYTVIGTAIGAIFFGLVADKIGRKNIILLTTILFSLFTFLSGFANDPVTFTIFRVIAG
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
IGLGGVMPNVIAIATEFSPKRVRTAIVSFIFCGYSVGAMAAALTSRSLLMTAGWKPVFWL
CCCCHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEECCCCHHHHH
AGLPLLFLPFLIKSIPESVSFLLGKGKIEEAKKVIAKVNPKLGEYATIEFTKPPTKEAGS
HCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCC
PVVKLFEEKRAISTIMFWISCFSAFVLIYSMNTWLPRLMMQSGYDLKSSLSFTAVMQIGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
IVGTLIFGPIVDKVGFKKVLVPLFFCGAIALSLIGFANSMFVGFLLIAIIGASSVGLQNM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCHHHH
SNAFVSQYYPSNMRSTAVGSTMAFGRLGGVVAPTFVGVLLSMHFLPQYNFSAIASAAVIG
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
GIAMLFVKEEHGIYYKEKKEIVSGDSNVTTAK
HHHHEEEECCCCCEEHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKSINPMNVIDESRIHSMHLWLIFWLFIVIAFDGYDVVIYGAAVPSLIKEWGISDVTAGA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHCCCCCCCCCC
IGSYTVIGTAIGAIFFGLVADKIGRKNIILLTTILFSLFTFLSGFANDPVTFTIFRVIAG
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
IGLGGVMPNVIAIATEFSPKRVRTAIVSFIFCGYSVGAMAAALTSRSLLMTAGWKPVFWL
CCCCHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEECCCCHHHHH
AGLPLLFLPFLIKSIPESVSFLLGKGKIEEAKKVIAKVNPKLGEYATIEFTKPPTKEAGS
HCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCC
PVVKLFEEKRAISTIMFWISCFSAFVLIYSMNTWLPRLMMQSGYDLKSSLSFTAVMQIGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
IVGTLIFGPIVDKVGFKKVLVPLFFCGAIALSLIGFANSMFVGFLLIAIIGASSVGLQNM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCHHHH
SNAFVSQYYPSNMRSTAVGSTMAFGRLGGVVAPTFVGVLLSMHFLPQYNFSAIASAAVIG
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
GIAMLFVKEEHGIYYKEKKEIVSGDSNVTTAK
HHHHEEEECCCCCEEHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9294456 [H]