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The map label for this gene is licC [H]

Identifier: 218904162

GI number: 218904162

Start: 2885843

End: 2887144

Strand: Reverse

Name: licC [H]

Synonym: BCAH820_3046

Alternate gene names: 218904162

Gene position: 2887144-2885843 (Counterclockwise)

Preceding gene: 218904163

Following gene: 218904161

Centisome position: 54.45

GC content: 34.87

Gene sequence:

>1302_bases
ATGAAACTGTTAGAAGGGACAAAAAACGGACTAGAACGAATCATCACACCACTAACAAATTATCTCGGAAATAGTAAAGT
TGTAAATGCGATTACATCAGGGATGATGATGACAATACCTGTTACGATCGGAGTTACATTATTTGCTATTTTAGGTAATC
TACCATTTAAAGGGTGGAAAGAATTTTTAATTCAAATTGGTTTGTATACGCATATGCAAGACATGATTAGTGCGACATTA
AGTTTGTTAGCAGTTTATATGGTTGTCATTATCGCATATTCCTATGCGAAAGAAGAAGGCATGAATGGAATGACGGCTGC
TGTTATAGCACTAGGTAGTTTCTTATGCTTAATGCCAATGTCTATTAAAGTAGGAGAAGAACAAATTCCAGCTATTTTAA
ATCAATATTTAGGTAGTGATGGAATATTCGTCGCCATGTTTGTCGGTGTTTTCACTAGTAAACTGTATTGTTCATTAAAG
AGAAAAAATATTGGGGTGAAATTGCCAGAATCAGTACCACCTATGGTAGCAGACGCAATTAACCCTGTGTTTATTTCAAT
TATCATTTTCACGCTTATATTCTTTATTAGAGTAATATTTGGCTTTACTCCATATGAAAATATTTTTAACTTTGTGAGTC
AGGTAATTTCTTTACCTGTAAAAGTCATCGGATCGTCTGTATGGTCAGTTATAGCTATCTTTACATTCATGAATATATGT
TGGTTCTTCGGTTTACACCCAGCACCAATTATAAATGTATGGTATAGTGCGACAGCTCCGTTATTCACGGCAGCTATTAC
AGCTTTTGCTTCGGGAACACCTTTTTCAGAAATTCCTTACTTAGCATTTACGTTAATGCATTTTGCAGTTGCTATTGGTG
GAACTGGAAATACGTTAGGTTTAGCAATAAACATGCTATTTGCGAAATCAGAGCAATATAAATCGCTTGGGAGGATTGGT
ATCGTTCCAAATATCTTTAACATAAATGAGCCAATTGTCTTCGGTTTGCCGCTTGTTTTGAATCCAATATATTTTATTCC
ATTAGTAGGATCTTCAATAGTTGGCGGGTTAATTTGTGTCGTATTCCTTAAAATTACAGGGATTTTATCTAACTTTAACC
CACTTATTGAATTACCATGGGTAACACCAGCGCCATTCGCAGCTTATATTTCTGGTGGCTGGTTACTACTTATCATGACT
GTTTTAATCATTATCTCTCAAATTCTATTATATTATCCGTTCTTTAAAATGGGGGATAAGAAAGCATATGAAGCAGAACA
ACAAGCAGCAACAGAGCAATAA

Upstream 100 bases:

>100_bases
TAAAGACGGGAAATATAAAGTTCAATCTGTAAATGATATGAGCTATGTAGAAAAAGGTAAAAAGTAGATGTATTAAAATT
CAAAAATGTTGGAGGTAATT

Downstream 100 bases:

>100_bases
TCATGTATCCAGCAGAATCCCGCTCGGTGTGGATAGTAATCAGTGAGGATGAACAAAACTTTATTGACTGTATTTTCGAA
TTATAAAAATAAAAAAATGT

Product: PTS system, IIC component

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Lic; PTS system lichenan-specific EIIC component [H]

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MKLLEGTKNGLERIITPLTNYLGNSKVVNAITSGMMMTIPVTIGVTLFAILGNLPFKGWKEFLIQIGLYTHMQDMISATL
SLLAVYMVVIIAYSYAKEEGMNGMTAAVIALGSFLCLMPMSIKVGEEQIPAILNQYLGSDGIFVAMFVGVFTSKLYCSLK
RKNIGVKLPESVPPMVADAINPVFISIIIFTLIFFIRVIFGFTPYENIFNFVSQVISLPVKVIGSSVWSVIAIFTFMNIC
WFFGLHPAPIINVWYSATAPLFTAAITAFASGTPFSEIPYLAFTLMHFAVAIGGTGNTLGLAINMLFAKSEQYKSLGRIG
IVPNIFNINEPIVFGLPLVLNPIYFIPLVGSSIVGGLICVVFLKITGILSNFNPLIELPWVTPAPFAAYISGGWLLLIMT
VLIIISQILLYYPFFKMGDKKAYEAEQQAATEQ

Sequences:

>Translated_433_residues
MKLLEGTKNGLERIITPLTNYLGNSKVVNAITSGMMMTIPVTIGVTLFAILGNLPFKGWKEFLIQIGLYTHMQDMISATL
SLLAVYMVVIIAYSYAKEEGMNGMTAAVIALGSFLCLMPMSIKVGEEQIPAILNQYLGSDGIFVAMFVGVFTSKLYCSLK
RKNIGVKLPESVPPMVADAINPVFISIIIFTLIFFIRVIFGFTPYENIFNFVSQVISLPVKVIGSSVWSVIAIFTFMNIC
WFFGLHPAPIINVWYSATAPLFTAAITAFASGTPFSEIPYLAFTLMHFAVAIGGTGNTLGLAINMLFAKSEQYKSLGRIG
IVPNIFNINEPIVFGLPLVLNPIYFIPLVGSSIVGGLICVVFLKITGILSNFNPLIELPWVTPAPFAAYISGGWLLLIMT
VLIIISQILLYYPFFKMGDKKAYEAEQQAATEQ
>Mature_433_residues
MKLLEGTKNGLERIITPLTNYLGNSKVVNAITSGMMMTIPVTIGVTLFAILGNLPFKGWKEFLIQIGLYTHMQDMISATL
SLLAVYMVVIIAYSYAKEEGMNGMTAAVIALGSFLCLMPMSIKVGEEQIPAILNQYLGSDGIFVAMFVGVFTSKLYCSLK
RKNIGVKLPESVPPMVADAINPVFISIIIFTLIFFIRVIFGFTPYENIFNFVSQVISLPVKVIGSSVWSVIAIFTFMNIC
WFFGLHPAPIINVWYSATAPLFTAAITAFASGTPFSEIPYLAFTLMHFAVAIGGTGNTLGLAINMLFAKSEQYKSLGRIG
IVPNIFNINEPIVFGLPLVLNPIYFIPLVGSSIVGGLICVVFLKITGILSNFNPLIELPWVTPAPFAAYISGGWLLLIMT
VLIIISQILLYYPFFKMGDKKAYEAEQQAATEQ

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=454, Percent_Identity=24.4493392070485, Blast_Score=125, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 47413; Mature: 47413

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLEGTKNGLERIITPLTNYLGNSKVVNAITSGMMMTIPVTIGVTLFAILGNLPFKGWK
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEHHHHHHHHHHHHHCCCCCHHHH
EFLIQIGLYTHMQDMISATLSLLAVYMVVIIAYSYAKEEGMNGMTAAVIALGSFLCLMPM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
SIKVGEEQIPAILNQYLGSDGIFVAMFVGVFTSKLYCSLKRKNIGVKLPESVPPMVADAI
HHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
NPVFISIIIFTLIFFIRVIFGFTPYENIFNFVSQVISLPVKVIGSSVWSVIAIFTFMNIC
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WFFGLHPAPIINVWYSATAPLFTAAITAFASGTPFSEIPYLAFTLMHFAVAIGGTGNTLG
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHH
LAINMLFAKSEQYKSLGRIGIVPNIFNINEPIVFGLPLVLNPIYFIPLVGSSIVGGLICV
HHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCHHCCCHHHHCHHHHHHHHHHHHHHHHHHH
VFLKITGILSNFNPLIELPWVTPAPFAAYISGGWLLLIMTVLIIISQILLYYPFFKMGDK
HHHHHHHHHHCCCCCEECCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHCCCC
KAYEAEQQAATEQ
HHHHHHHHHCCCC
>Mature Secondary Structure
MKLLEGTKNGLERIITPLTNYLGNSKVVNAITSGMMMTIPVTIGVTLFAILGNLPFKGWK
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEHHHHHHHHHHHHHCCCCCHHHH
EFLIQIGLYTHMQDMISATLSLLAVYMVVIIAYSYAKEEGMNGMTAAVIALGSFLCLMPM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
SIKVGEEQIPAILNQYLGSDGIFVAMFVGVFTSKLYCSLKRKNIGVKLPESVPPMVADAI
HHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
NPVFISIIIFTLIFFIRVIFGFTPYENIFNFVSQVISLPVKVIGSSVWSVIAIFTFMNIC
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WFFGLHPAPIINVWYSATAPLFTAAITAFASGTPFSEIPYLAFTLMHFAVAIGGTGNTLG
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHH
LAINMLFAKSEQYKSLGRIGIVPNIFNINEPIVFGLPLVLNPIYFIPLVGSSIVGGLICV
HHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCHHCCCHHHHCHHHHHHHHHHHHHHHHHHH
VFLKITGILSNFNPLIELPWVTPAPFAAYISGGWLLLIMTVLIIISQILLYYPFFKMGDK
HHHHHHHHHHCCCCCEECCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHCCCC
KAYEAEQQAATEQ
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]