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The map label for this gene is bglC [H]

Identifier: 218904160

GI number: 218904160

Start: 2883976

End: 2885361

Strand: Reverse

Name: bglC [H]

Synonym: BCAH820_3044

Alternate gene names: 218904160

Gene position: 2885361-2883976 (Counterclockwise)

Preceding gene: 218904161

Following gene: 218904159

Centisome position: 54.41

GC content: 34.78

Gene sequence:

>1386_bases
ATGCTCAACACTACATTTAAAAACGACTTTTTATGGGGCGCTTCCACAAGCGCCTATCAAGTAGAAGGTGCTTATAATGA
GGATGGAAAAGGCCTTTCTGTTCAAGATGTGAAGGATATTCCTGAAGGTACGTCAGATTTCAAAGTTTGTAGTGATCATT
ACCATCATTTTAAAGAAGATATAAAGTTATTTTCTGAATTAGGACTGAAAGTATATCGTTTTTCTATCGCTTGGACTCGA
ATTCTTCCGAATGGAACTGGAGAAGTGAATGAAAAAGGCATTGCGTTTTATAGTGATCTTATTGATGAATTGCTGAAGCA
TAATATTGTTCCGCTAGTAACGATGTATCATTTTGATTTACCGTATGAATTAGAGAAAAAGGGTGGCTGGAGTAACCGCG
CTACTATCGATGCTTTTGTTACATATTGTGAAATTCTATTTGATCGATATGGAGATAGGGTAAAGAATTGGTTAACGATT
AATGAGCAGAATATGATGATTTTACACGGTGGGGCTATTGGTACATCTGTATTGTCTCAAAAAGAGTTATATCAACAAAA
TCATCATATGTTGTTAGCTGAGGCTAAGGTGACAAACTTATGCCATAAGATGATACATGATGCAAAAATTGGTCCAGCTC
CAAATATTAGTTATGTGTATCCGAAAACGTGCAATCCGAATGATATAATTGCAGCGCAAAATTGTAACGCAATTCGTAAC
TGGTTATATCTTGATATGGCTGTATATGGACGATATAACAATATCGCTTGGAATTTCATGAAAAGTAAAAACATCGAACC
AGAAATTTTAGATGGAGATATGGAGATTTTATCTAGTTCTAAACCAGACTATATTGCTTTTAACTATTATTCTTCTATTA
CTGTTAGTGAGTATGATGAGAACTTTGTAATTGACGAAGCTGGTGATCAACAAATTGAAGTAGGTGAAGAAGGATTCTTC
ATGGGGGATGATAATGAATTTCTAGAGTTAACTGATTTCGGTTGGGAGATTGATCCGATTGGCTTCCGAGCTACATTAAG
AGAAGTAAATGATCGATATAACTTGCCAATTATCGTTACTGAGAATGGGATAGGCGCTTACGACAAAGTAGATGAAGATG
GAATTGTGCAAGATCATTACCGAATCGATTATTTGAAAAAGCATATTGAACAGATGGAATTGGCAATTGCAGACGGAGTG
AATCTAATGGGTTACTGTCCTTGGGCGGCAATTGATTTAATTTCTACGCATCAAGGTTTCAGAAAAAGATATGGCTTTAT
TTATATAAATCGTGATGAAGACGATTTAAAAGATTTAAAAAGAATAAAGAAACAGAGCTTCTATTGGTATAAAGAAGTTA
TTTCATCAAATGGAAAAGAACGATAA

Upstream 100 bases:

>100_bases
TTGCAGAAGAGCTTATAAGTGTTTATGAAACATTTTTAGTGAAACAAAATTAAAAGAAAGAAACTATCACAATACTATTT
TTGAAAGGGAAAGGTAAAAT

Downstream 100 bases:

>100_bases
CATGTAGTTTCGAAGTTCACATCATAGAGTGCGCACCTCAAGAAAAAATTATTTACTTTGAGGTGCGCACTTTTTATATG
TAAAATAACTATATTTTTCG

Product: beta-glucosidase

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MLNTTFKNDFLWGASTSAYQVEGAYNEDGKGLSVQDVKDIPEGTSDFKVCSDHYHHFKEDIKLFSELGLKVYRFSIAWTR
ILPNGTGEVNEKGIAFYSDLIDELLKHNIVPLVTMYHFDLPYELEKKGGWSNRATIDAFVTYCEILFDRYGDRVKNWLTI
NEQNMMILHGGAIGTSVLSQKELYQQNHHMLLAEAKVTNLCHKMIHDAKIGPAPNISYVYPKTCNPNDIIAAQNCNAIRN
WLYLDMAVYGRYNNIAWNFMKSKNIEPEILDGDMEILSSSKPDYIAFNYYSSITVSEYDENFVIDEAGDQQIEVGEEGFF
MGDDNEFLELTDFGWEIDPIGFRATLREVNDRYNLPIIVTENGIGAYDKVDEDGIVQDHYRIDYLKKHIEQMELAIADGV
NLMGYCPWAAIDLISTHQGFRKRYGFIYINRDEDDLKDLKRIKKQSFYWYKEVISSNGKER

Sequences:

>Translated_461_residues
MLNTTFKNDFLWGASTSAYQVEGAYNEDGKGLSVQDVKDIPEGTSDFKVCSDHYHHFKEDIKLFSELGLKVYRFSIAWTR
ILPNGTGEVNEKGIAFYSDLIDELLKHNIVPLVTMYHFDLPYELEKKGGWSNRATIDAFVTYCEILFDRYGDRVKNWLTI
NEQNMMILHGGAIGTSVLSQKELYQQNHHMLLAEAKVTNLCHKMIHDAKIGPAPNISYVYPKTCNPNDIIAAQNCNAIRN
WLYLDMAVYGRYNNIAWNFMKSKNIEPEILDGDMEILSSSKPDYIAFNYYSSITVSEYDENFVIDEAGDQQIEVGEEGFF
MGDDNEFLELTDFGWEIDPIGFRATLREVNDRYNLPIIVTENGIGAYDKVDEDGIVQDHYRIDYLKKHIEQMELAIADGV
NLMGYCPWAAIDLISTHQGFRKRYGFIYINRDEDDLKDLKRIKKQSFYWYKEVISSNGKER
>Mature_461_residues
MLNTTFKNDFLWGASTSAYQVEGAYNEDGKGLSVQDVKDIPEGTSDFKVCSDHYHHFKEDIKLFSELGLKVYRFSIAWTR
ILPNGTGEVNEKGIAFYSDLIDELLKHNIVPLVTMYHFDLPYELEKKGGWSNRATIDAFVTYCEILFDRYGDRVKNWLTI
NEQNMMILHGGAIGTSVLSQKELYQQNHHMLLAEAKVTNLCHKMIHDAKIGPAPNISYVYPKTCNPNDIIAAQNCNAIRN
WLYLDMAVYGRYNNIAWNFMKSKNIEPEILDGDMEILSSSKPDYIAFNYYSSITVSEYDENFVIDEAGDQQIEVGEEGFF
MGDDNEFLELTDFGWEIDPIGFRATLREVNDRYNLPIIVTENGIGAYDKVDEDGIVQDHYRIDYLKKHIEQMELAIADGV
NLMGYCPWAAIDLISTHQGFRKRYGFIYINRDEDDLKDLKRIKKQSFYWYKEVISSNGKER

Specific function: Is able to catalyze the hydrolysis of aryl-phospho-beta- D-glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Is not essential for growth on arbutin and salicin as the sole carbon source [H]

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=478, Percent_Identity=32.0083682008368, Blast_Score=224, Evalue=2e-58,
Organism=Homo sapiens, GI110681710, Length=486, Percent_Identity=31.8930041152263, Blast_Score=222, Evalue=5e-58,
Organism=Homo sapiens, GI13273313, Length=488, Percent_Identity=30.9426229508197, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI24497614, Length=490, Percent_Identity=26.9387755102041, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI28376633, Length=472, Percent_Identity=27.5423728813559, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI190360571, Length=96, Percent_Identity=43.75, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI2367174, Length=484, Percent_Identity=40.2892561983471, Blast_Score=360, Evalue=1e-101,
Organism=Escherichia coli, GI2367270, Length=472, Percent_Identity=42.1610169491525, Blast_Score=353, Evalue=1e-98,
Organism=Escherichia coli, GI1789070, Length=487, Percent_Identity=36.5503080082135, Blast_Score=308, Evalue=4e-85,
Organism=Caenorhabditis elegans, GI17552856, Length=483, Percent_Identity=31.2629399585921, Blast_Score=204, Evalue=8e-53,
Organism=Caenorhabditis elegans, GI17539390, Length=486, Percent_Identity=29.4238683127572, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI21356577, Length=474, Percent_Identity=29.3248945147679, Blast_Score=200, Evalue=1e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 53209; Mature: 53209

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNTTFKNDFLWGASTSAYQVEGAYNEDGKGLSVQDVKDIPEGTSDFKVCSDHYHHFKED
CCCCCCCCCEEECCCCCCEEEECCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHH
IKLFSELGLKVYRFSIAWTRILPNGTGEVNEKGIAFYSDLIDELLKHNIVPLVTMYHFDL
HHHHHHCCCEEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCC
PYELEKKGGWSNRATIDAFVTYCEILFDRYGDRVKNWLTINEQNMMILHGGAIGTSVLSQ
CEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEECCCHHHHHHHH
KELYQQNHHMLLAEAKVTNLCHKMIHDAKIGPAPNISYVYPKTCNPNDIIAAQNCNAIRN
HHHHHCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCEEEECCCHHHHH
WLYLDMAVYGRYNNIAWNFMKSKNIEPEILDGDMEILSSSKPDYIAFNYYSSITVSEYDE
HHEEEHHEECCCCCEEEEEHHCCCCCCEEECCCHHHHCCCCCCEEEEEEECEEEEECCCC
NFVIDEAGDQQIEVGEEGFFMGDDNEFLELTDFGWEIDPIGFRATLREVNDRYNLPIIVT
CEEEECCCCCEEEECCCCCEECCCCCEEEEECCCCEECCCCHHHHHHHHHCCCCCCEEEE
ENGIGAYDKVDEDGIVQDHYRIDYLKKHIEQMELAIADGVNLMGYCPWAAIDLISTHQGF
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHH
RKRYGFIYINRDEDDLKDLKRIKKQSFYWYKEVISSNGKER
HHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLNTTFKNDFLWGASTSAYQVEGAYNEDGKGLSVQDVKDIPEGTSDFKVCSDHYHHFKED
CCCCCCCCCEEECCCCCCEEEECCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHH
IKLFSELGLKVYRFSIAWTRILPNGTGEVNEKGIAFYSDLIDELLKHNIVPLVTMYHFDL
HHHHHHCCCEEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCC
PYELEKKGGWSNRATIDAFVTYCEILFDRYGDRVKNWLTINEQNMMILHGGAIGTSVLSQ
CEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEECCCHHHHHHHH
KELYQQNHHMLLAEAKVTNLCHKMIHDAKIGPAPNISYVYPKTCNPNDIIAAQNCNAIRN
HHHHHCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCEEEECCCHHHHH
WLYLDMAVYGRYNNIAWNFMKSKNIEPEILDGDMEILSSSKPDYIAFNYYSSITVSEYDE
HHEEEHHEECCCCCEEEEEHHCCCCCCEEECCCHHHHCCCCCCEEEEEEECEEEEECCCC
NFVIDEAGDQQIEVGEEGFFMGDDNEFLELTDFGWEIDPIGFRATLREVNDRYNLPIIVT
CEEEECCCCCEEEECCCCCEECCCCCEEEEECCCCEECCCCHHHHHHHHHCCCCCCEEEE
ENGIGAYDKVDEDGIVQDHYRIDYLKKHIEQMELAIADGVNLMGYCPWAAIDLISTHQGF
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHH
RKRYGFIYINRDEDDLKDLKRIKKQSFYWYKEVISSNGKER
HHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7704255; 8969502; 9384377; 2841296 [H]