Click here to switch to the map view.

The map label for this gene is sigW [H]

Identifier: 218904082

GI number: 218904082

Start: 2804108

End: 2804686

Strand: Reverse

Name: sigW [H]

Synonym: BCAH820_2966

Alternate gene names: 218904082

Gene position: 2804686-2804108 (Counterclockwise)

Preceding gene: 218904085

Following gene: 218904081

Centisome position: 52.89

GC content: 34.37

Gene sequence:

>579_bases
TTGGATGAAGTACAATTAAAAGAATGGCTATATAAAATGGAGTCTGGGGACCAAGAAGCCTTTCAGATTATCTATGAATA
TACATGTAAAGATATTTATAGAACAGTAGTATTTTTAGTAGGAAGTCAAAACCAAGATGTAGACGATATAGTTAATGAGG
TGTACATCAAAATGTGGAAGTCCGTAACCAACTATGATATGAATCGTTCATTTCGTTTTTGGTTACATGGACTAGTTGTC
AAGCAAGTACAGGATTGGCGTCGTAAATCGTGGCGACGATTTCGAATCTTTGAAAAGAAGAAAATGTATGAACAAGATCG
GTCTTACATAATGGATGAAGCTATTTTACATAAAGAAACACGAAGTGAACTAGTAGAAGTTGTACAAAATTTATCTTATA
AACATCGTGAAGTAGTTATTATGCGTTACTTCCATGAATATAGCTTGGATGAAATTGCTGCACTTCTTCAAATCCCTATT
GGTACAGTGAAATCTCGACTACACACAGCACTAAAACGATTAAGAATGGAAATGGAACAAATGCCAAACGAAAGGGAGGA
AGAAGTAAATGGATTTTGA

Upstream 100 bases:

>100_bases
TTTATATTTTTATTGTAATAAATAAATTTTTATGTAAAATGAACCTTTTGTGAAAAACGAGCGAATATAGTGTGAAAGAT
CATGAGAGGGGAACGAAACT

Downstream 100 bases:

>100_bases
AAGGTATGTAACGAATGAACTAAAAAGAAAAGCAGAGAGTCTAGATCCGTCTCCAAGTTTAGATAATAAAGTGCAAAACT
CTTTTTATAAATACCAACAG

Product: RNA polymerase sigma factor

Products: NA

Alternate protein names: Sigma-W factor [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MDEVQLKEWLYKMESGDQEAFQIIYEYTCKDIYRTVVFLVGSQNQDVDDIVNEVYIKMWKSVTNYDMNRSFRFWLHGLVV
KQVQDWRRKSWRRFRIFEKKKMYEQDRSYIMDEAILHKETRSELVEVVQNLSYKHREVVIMRYFHEYSLDEIAALLQIPI
GTVKSRLHTALKRLRMEMEQMPNEREEEVNGF

Sequences:

>Translated_192_residues
MDEVQLKEWLYKMESGDQEAFQIIYEYTCKDIYRTVVFLVGSQNQDVDDIVNEVYIKMWKSVTNYDMNRSFRFWLHGLVV
KQVQDWRRKSWRRFRIFEKKKMYEQDRSYIMDEAILHKETRSELVEVVQNLSYKHREVVIMRYFHEYSLDEIAALLQIPI
GTVKSRLHTALKRLRMEMEQMPNEREEEVNGF
>Mature_192_residues
MDEVQLKEWLYKMESGDQEAFQIIYEYTCKDIYRTVVFLVGSQNQDVDDIVNEVYIKMWKSVTNYDMNRSFRFWLHGLVV
KQVQDWRRKSWRRFRIFEKKKMYEQDRSYIMDEAILHKETRSELVEVVQNLSYKHREVVIMRYFHEYSLDEIAALLQIPI
GTVKSRLHTALKRLRMEMEQMPNEREEEVNGF

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in transport processes and detoxification [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014294
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 23540; Mature: 23540

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEVQLKEWLYKMESGDQEAFQIIYEYTCKDIYRTVVFLVGSQNQDVDDIVNEVYIKMWK
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
SVTNYDMNRSFRFWLHGLVVKQVQDWRRKSWRRFRIFEKKKMYEQDRSYIMDEAILHKET
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSELVEVVQNLSYKHREVVIMRYFHEYSLDEIAALLQIPIGTVKSRLHTALKRLRMEMEQ
HHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
MPNEREEEVNGF
CCCHHHHHCCCC
>Mature Secondary Structure
MDEVQLKEWLYKMESGDQEAFQIIYEYTCKDIYRTVVFLVGSQNQDVDDIVNEVYIKMWK
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
SVTNYDMNRSFRFWLHGLVVKQVQDWRRKSWRRFRIFEKKKMYEQDRSYIMDEAILHKET
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSELVEVVQNLSYKHREVVIMRYFHEYSLDEIAALLQIPIGTVKSRLHTALKRLRMEMEQ
HHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
MPNEREEEVNGF
CCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 12207695 [H]