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The map label for this gene is kstR2 [H]

Identifier: 218904039

GI number: 218904039

Start: 2761237

End: 2761827

Strand: Reverse

Name: kstR2 [H]

Synonym: BCAH820_2923

Alternate gene names: 218904039

Gene position: 2761827-2761237 (Counterclockwise)

Preceding gene: 218904040

Following gene: 218904038

Centisome position: 52.08

GC content: 30.63

Gene sequence:

>591_bases
ATGAAAAGAATATCAAAAGAACCAGATGTTAGAAGGCAAGAGTTGATGGATATTGGTTTTGAACTATATATGAAAAATGG
TATGAAAGGATTTGGTATAAAAGATGTTGTGAATCATGCAGGTGTAGCAACGGGCTTATTTTATTATTACTTCAAGTCTA
AAGAGAATTTTGTTGATGAAGTATTAAATGATTTTATTGTGAAAAATATGGAGTTAATTGAAGAAATACTTATTTCTAAT
GAACGGTCTGTCATGCAAAAGCTGAAAGATTCTCTAAATATATTTTGGACATTTATCGAAAAATTAGCACCCTATAAAAA
TGTGAGTTCGTTTCAGACGGAACAACATTTTCAACTGGAACAGAAATTATTTACGCGAATGCAGCCATTAATTCGACAAG
TAATCGAAGAAGGGGTGAAAACTGGGATTTTTAATAATGATAACTCATTATTAACATCAGGATTTATTTTATACGGTCTT
AGCAGTATTGCTCATTCAGAGGTGAATTTGAATCTAGACACGAAGCAAGAAATGATTAATTTAGTATTAAATACACTACG
ATACGATCAAAGTGAAGGAGAATGTATATGA

Upstream 100 bases:

>100_bases
TTACTCTTTTTTTGTGGAAACTAATATTGACTGAATATAGTTCAGTCGTTTATGATTGAATCAGATTCAGTCGAGGGTAA
AACATAGTAGGAGATGACCT

Downstream 100 bases:

>100_bases
AAATTATGATTGATGGAAACAATATTTCGAATGAACAACTTACAAAGTGGAAAAGAGAACGTATAAAAAAAGTTTTCAAT
ACATTAGGAAATAAAGAGCC

Product: transcriptional regulator, TetR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MKRISKEPDVRRQELMDIGFELYMKNGMKGFGIKDVVNHAGVATGLFYYYFKSKENFVDEVLNDFIVKNMELIEEILISN
ERSVMQKLKDSLNIFWTFIEKLAPYKNVSSFQTEQHFQLEQKLFTRMQPLIRQVIEEGVKTGIFNNDNSLLTSGFILYGL
SSIAHSEVNLNLDTKQEMINLVLNTLRYDQSEGECI

Sequences:

>Translated_196_residues
MKRISKEPDVRRQELMDIGFELYMKNGMKGFGIKDVVNHAGVATGLFYYYFKSKENFVDEVLNDFIVKNMELIEEILISN
ERSVMQKLKDSLNIFWTFIEKLAPYKNVSSFQTEQHFQLEQKLFTRMQPLIRQVIEEGVKTGIFNNDNSLLTSGFILYGL
SSIAHSEVNLNLDTKQEMINLVLNTLRYDQSEGECI
>Mature_196_residues
MKRISKEPDVRRQELMDIGFELYMKNGMKGFGIKDVVNHAGVATGLFYYYFKSKENFVDEVLNDFIVKNMELIEEILISN
ERSVMQKLKDSLNIFWTFIEKLAPYKNVSSFQTEQHFQLEQKLFTRMQPLIRQVIEEGVKTGIFNNDNSLLTSGFILYGL
SSIAHSEVNLNLDTKQEMINLVLNTLRYDQSEGECI

Specific function: Controls the expression of a small regulon that may play a role in the utilization of cholesterol [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22813; Mature: 22813

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRISKEPDVRRQELMDIGFELYMKNGMKGFGIKDVVNHAGVATGLFYYYFKSKENFVDE
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHH
VLNDFIVKNMELIEEILISNERSVMQKLKDSLNIFWTFIEKLAPYKNVSSFQTEQHFQLE
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
QKLFTRMQPLIRQVIEEGVKTGIFNNDNSLLTSGFILYGLSSIAHSEVNLNLDTKQEMIN
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LVLNTLRYDQSEGECI
HHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKRISKEPDVRRQELMDIGFELYMKNGMKGFGIKDVVNHAGVATGLFYYYFKSKENFVDE
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHH
VLNDFIVKNMELIEEILISNERSVMQKLKDSLNIFWTFIEKLAPYKNVSSFQTEQHFQLE
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
QKLFTRMQPLIRQVIEEGVKTGIFNNDNSLLTSGFILYGLSSIAHSEVNLNLDTKQEMIN
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LVLNTLRYDQSEGECI
HHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA