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The map label for this gene is dapL [H]

Identifier: 218904017

GI number: 218904017

Start: 2745407

End: 2746606

Strand: Direct

Name: dapL [H]

Synonym: BCAH820_2901

Alternate gene names: 218904017

Gene position: 2745407-2746606 (Clockwise)

Preceding gene: 218904015

Following gene: 218904018

Centisome position: 51.77

GC content: 36.42

Gene sequence:

>1200_bases
ATGACTTACACGTTAGCAACTAGAATGAAAGCATTCCAATCTTCTATATTTAGTGAATTAGGGGCCTATAAAAAAGAAAA
AATTGCAGCAGGTCACAAAATGATTGATTTAAGTATCGGGAATCCTGATATGCCACCTGCGGATTTCGTAAGAGAAGAAA
TGGTACATACAGCAAATCAAAAAGAAAGCTATGGATACACATTAAGTGGCATTCAAGAATTTCACGAAGCTGTAACTGAA
TATTACAACAACACTCATAATGTTATATTAAATGCCGATAAAGAAGTTTTATTATTAATGGGTTCACAAGATGGACTCGT
TCATTTACCTATGGTTTATGCGAATCCGGGAGATATTATATTAGTTCCTGATCCAGGATATACAGCTTATGAAACAGGAA
TTCAAATGGCTGGTGCAACATCTTACTACATGCCTTTAAAAAAAGAAAATGATTTCTTACCTAACTTAGAGCTAATTCCT
GAAGAAATTGCAGATAAAGCGAAGATGATGATTTTAAACTTCCCAGGGAATCCGGTTCCAGCAATGGCTCATGAATATTT
CTTTAAAGAAGTAATCGCATTTGCGAAAAAGCATAACATTATTGTTGTCCATGATTTTGCTTATGCTGAATTTTATTTTG
ATGGTAATAAACCAATTAGCTTCCTCTCTGTGCCTGGTGCTAAAGAAGTTGGCGTAGAAATTAACTCTTTGTCAAAAAGT
TATAGTTTAGCAGGTAGCCGTATTGGTTATATGATTGGTAATGAAGAAATTGTCGGGGCACTTACACAATTTAAATCTAA
TACAGATTACGGAGTATTTTTACCAATTCAAAAAGCGGCATGTGCTGCACTAAGAAATGGTGCTGCTTTTTGTGAGAAAA
ACCGTGGTATTTATCAAGAACGTAGAGATACTTTAGTCGATGGGTTCCGAACATTTGGCTGGCATGTTGAAAAACCAGCT
GGCAGTATGTTCGTCTGGGCCGAAATTCCGAAAGGCTGGACTTCTATAGACTTCGCTTATGCATTAATGGATCGTGCGAA
TGTCGTTGTCACACCAGGTCATGCATTCGGACCTCACGGAGAAGGGTTTGTACGCATTGCACTCGTTCAAGATAAAGTAG
TGTTACAACAAGTTGTTGAAAACATTAGAAATAGTGGTATTTTCGCCCTTGAAAAAGTAGATGAATTAGTTAAAAATTAG

Upstream 100 bases:

>100_bases
AATCGTTTTAATTTTCATAAAAAAATGATAAAATGTACTCATGTGTTTTCAGAATAATTAAAAACGCAGAAAGAAAACAC
TGTTTTTAGGAGGGGTTTTG

Downstream 100 bases:

>100_bases
TTCCCACTCCCCTGCTTAACTTTAGCAGGGGTATTATTCATTGGAGGTACTTTCATATGCATATTAAAGACACGCTTCCC
CATCGTTATCCATTTTTAAT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MTYTLATRMKAFQSSIFSELGAYKKEKIAAGHKMIDLSIGNPDMPPADFVREEMVHTANQKESYGYTLSGIQEFHEAVTE
YYNNTHNVILNADKEVLLLMGSQDGLVHLPMVYANPGDIILVPDPGYTAYETGIQMAGATSYYMPLKKENDFLPNLELIP
EEIADKAKMMILNFPGNPVPAMAHEYFFKEVIAFAKKHNIIVVHDFAYAEFYFDGNKPISFLSVPGAKEVGVEINSLSKS
YSLAGSRIGYMIGNEEIVGALTQFKSNTDYGVFLPIQKAACAALRNGAAFCEKNRGIYQERRDTLVDGFRTFGWHVEKPA
GSMFVWAEIPKGWTSIDFAYALMDRANVVVTPGHAFGPHGEGFVRIALVQDKVVLQQVVENIRNSGIFALEKVDELVKN

Sequences:

>Translated_399_residues
MTYTLATRMKAFQSSIFSELGAYKKEKIAAGHKMIDLSIGNPDMPPADFVREEMVHTANQKESYGYTLSGIQEFHEAVTE
YYNNTHNVILNADKEVLLLMGSQDGLVHLPMVYANPGDIILVPDPGYTAYETGIQMAGATSYYMPLKKENDFLPNLELIP
EEIADKAKMMILNFPGNPVPAMAHEYFFKEVIAFAKKHNIIVVHDFAYAEFYFDGNKPISFLSVPGAKEVGVEINSLSKS
YSLAGSRIGYMIGNEEIVGALTQFKSNTDYGVFLPIQKAACAALRNGAAFCEKNRGIYQERRDTLVDGFRTFGWHVEKPA
GSMFVWAEIPKGWTSIDFAYALMDRANVVVTPGHAFGPHGEGFVRIALVQDKVVLQQVVENIRNSGIFALEKVDELVKN
>Mature_398_residues
TYTLATRMKAFQSSIFSELGAYKKEKIAAGHKMIDLSIGNPDMPPADFVREEMVHTANQKESYGYTLSGIQEFHEAVTEY
YNNTHNVILNADKEVLLLMGSQDGLVHLPMVYANPGDIILVPDPGYTAYETGIQMAGATSYYMPLKKENDFLPNLELIPE
EIADKAKMMILNFPGNPVPAMAHEYFFKEVIAFAKKHNIIVVHDFAYAEFYFDGNKPISFLSVPGAKEVGVEINSLSKSY
SLAGSRIGYMIGNEEIVGALTQFKSNTDYGVFLPIQKAACAALRNGAAFCEKNRGIYQERRDTLVDGFRTFGWHVEKPAG
SMFVWAEIPKGWTSIDFAYALMDRANVVVTPGHAFGPHGEGFVRIALVQDKVVLQQVVENIRNSGIFALEKVDELVKN

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=346, Percent_Identity=24.5664739884393, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI56713254, Length=346, Percent_Identity=24.5664739884393, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI95147551, Length=398, Percent_Identity=24.1206030150754, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI169881279, Length=398, Percent_Identity=24.1206030150754, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI169881281, Length=395, Percent_Identity=23.0379746835443, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI4507369, Length=382, Percent_Identity=23.5602094240838, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1788722, Length=385, Percent_Identity=38.4415584415584, Blast_Score=285, Evalue=3e-78,
Organism=Escherichia coli, GI1786816, Length=382, Percent_Identity=21.4659685863874, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1788627, Length=229, Percent_Identity=25.764192139738, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71994476, Length=290, Percent_Identity=25.8620689655172, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI71994472, Length=290, Percent_Identity=25.8620689655172, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17567369, Length=348, Percent_Identity=26.1494252873563, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17567663, Length=371, Percent_Identity=26.1455525606469, Blast_Score=92, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6322401, Length=389, Percent_Identity=23.6503856041131, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28573069, Length=413, Percent_Identity=21.5496368038741, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24646114, Length=413, Percent_Identity=21.5496368038741, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28573067, Length=413, Percent_Identity=21.5496368038741, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28573065, Length=413, Percent_Identity=21.5496368038741, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI18859735, Length=225, Percent_Identity=26.2222222222222, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 44384; Mature: 44253

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYTLATRMKAFQSSIFSELGAYKKEKIAAGHKMIDLSIGNPDMPPADFVREEMVHTANQ
CEEEHHHHHHHHHHHHHHHHCCHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHCCC
KESYGYTLSGIQEFHEAVTEYYNNTHNVILNADKEVLLLMGSQDGLVHLPMVYANPGDII
CCCCCEEHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCEEEEEEEEECCCCEE
LVPDPGYTAYETGIQMAGATSYYMPLKKENDFLPNLELIPEEIADKAKMMILNFPGNPVP
EECCCCCCHHHHCEEECCCCEEEEECCCCCCCCCCHHCCCHHHCCCEEEEEEECCCCCCC
AMAHEYFFKEVIAFAKKHNIIVVHDFAYAEFYFDGNKPISFLSVPGAKEVGVEINSLSKS
HHHHHHHHHHHHHHHHHCCEEEEEECEEEEEEECCCCCEEEEECCCCHHHCEEHHHCCHH
YSLAGSRIGYMIGNEEIVGALTQFKSNTDYGVFLPIQKAACAALRNGAAFCEKNRGIYQE
HHCCCCEEEEEECCHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHCCHHHHHCCCCHHHH
RRDTLVDGFRTFGWHVEKPAGSMFVWAEIPKGWTSIDFAYALMDRANVVVTPGHAFGPHG
HHHHHHHHHHHCCEEEECCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEECCCCCCCCC
EGFVRIALVQDKVVLQQVVENIRNSGIFALEKVDELVKN
CCEEEEEEEHHHHHHHHHHHHHHCCCEEEHHHHHHHHCC
>Mature Secondary Structure 
TYTLATRMKAFQSSIFSELGAYKKEKIAAGHKMIDLSIGNPDMPPADFVREEMVHTANQ
EEEHHHHHHHHHHHHHHHHCCHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHCCC
KESYGYTLSGIQEFHEAVTEYYNNTHNVILNADKEVLLLMGSQDGLVHLPMVYANPGDII
CCCCCEEHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCEEEEEEEEECCCCEE
LVPDPGYTAYETGIQMAGATSYYMPLKKENDFLPNLELIPEEIADKAKMMILNFPGNPVP
EECCCCCCHHHHCEEECCCCEEEEECCCCCCCCCCHHCCCHHHCCCEEEEEEECCCCCCC
AMAHEYFFKEVIAFAKKHNIIVVHDFAYAEFYFDGNKPISFLSVPGAKEVGVEINSLSKS
HHHHHHHHHHHHHHHHHCCEEEEEECEEEEEEECCCCCEEEEECCCCHHHCEEHHHCCHH
YSLAGSRIGYMIGNEEIVGALTQFKSNTDYGVFLPIQKAACAALRNGAAFCEKNRGIYQE
HHCCCCEEEEEECCHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHCCHHHHHCCCCHHHH
RRDTLVDGFRTFGWHVEKPAGSMFVWAEIPKGWTSIDFAYALMDRANVVVTPGHAFGPHG
HHHHHHHHHHHCCEEEECCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEECCCCCCCCC
EGFVRIALVQDKVVLQQVVENIRNSGIFALEKVDELVKN
CCEEEEEEEHHHHHHHHHHHHHHCCCEEEHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA