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The map label for this gene is yogA [H]

Identifier: 218903780

GI number: 218903780

Start: 2531717

End: 2532706

Strand: Direct

Name: yogA [H]

Synonym: BCAH820_2664

Alternate gene names: 218903780

Gene position: 2531717-2532706 (Clockwise)

Preceding gene: 218903779

Following gene: 218903781

Centisome position: 47.74

GC content: 36.46

Gene sequence:

>990_bases
ATGAAAGCAATTGTACATCAATATAAAAAAGGGGTAGAGGGATTAGAAAATAAATTCTTATCTGAAACACATCCTAATGC
CGGGGAAGTAAAAGTAAAGTTAAAAGCAGCAGGATTAAATCATAGGGATTTATTTATTATAAACAATAGAAAAGAAATGG
ATCTACCGTTAGTAATAGGATCAGATGGTGCAGGTATTGTTACAGAAATAGGAGAAGGTGTTTCAGCTGATTTATTACAA
GCCGAGGTTATTATTAATCCTAGTATTGGATGGGAGAATATCGCCGAAGTACCAGAGTTACCAGAGGTATTAGGGGGACC
AAAAGATGGAACGTTTGCTGAATATGTAATAGTGCCCGCTGAAAATGTAGTGGGAAAACCGTCATATCTTACTTGGGAAG
AGTCTGGCGTTTTGGCTTTATCGGCACTGACTGCATATAGAGCGCTTTTTACAAAGGGTAGATTGAAGTGTGGAGAACAT
GTTTTAATTCCGGGGATAGGCGGCGGTGTAGCGACATTTGCCATGTTATTTGCAAAAGCAATTGGCGCAAAAGTAAGTGT
TACGTCAAGGGTAGAAAACAAAAGAAAGTTTGCCGAAACATATGGCGCAGACTTTTCTTTTAATAGTTCTGGAAATTGGG
AAGAGAGTTTATGCGGAGGAAAAGTAGATTTAATAATTGATAGTATAGGTCCAGCAACATTCATAAAATACTTTGATGTA
TTAAACCCAAATGGGAGAATTGTTAATTTTGGTGCAAGTTCAGGAGATAAAATAGAATTACCTTTAAGAGCGTTATTTTA
TAACCAAATTGATATTATGGGAACATCTATGGGTAGCCGTGAGGAATTTGATGAAATGATTAGGTTTATAGAGAAATATA
AGATTAAACCAATTATAGATAAAGTTTATTCGTTGGAAGAAGCAATTCAAGCGTTGAGCCGTATGGAGCAGGGAGAACAG
TTCGGTAATATCGCTCTACGTATGGAATAA

Upstream 100 bases:

>100_bases
TTGTTATAACGATATACATTATTTCTAATTATTAGAGACAGATTAGTTTATTTATTTCGATATTTCTAGTACATTGAAAA
TATTAAGGGGGAATGAAGCA

Downstream 100 bases:

>100_bases
AAATATGATTTAATAACCTATGTTTTTATATGTATATGTTATGTAATATATACACTTTTAGTTAGTGGATTATATGATTT
TAAAGGTTTTTCCATCATAT

Product: oxidoreductase, zinc-binding dehydrogenase family

Products: aldehyde; ketone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MKAIVHQYKKGVEGLENKFLSETHPNAGEVKVKLKAAGLNHRDLFIINNRKEMDLPLVIGSDGAGIVTEIGEGVSADLLQ
AEVIINPSIGWENIAEVPELPEVLGGPKDGTFAEYVIVPAENVVGKPSYLTWEESGVLALSALTAYRALFTKGRLKCGEH
VLIPGIGGGVATFAMLFAKAIGAKVSVTSRVENKRKFAETYGADFSFNSSGNWEESLCGGKVDLIIDSIGPATFIKYFDV
LNPNGRIVNFGASSGDKIELPLRALFYNQIDIMGTSMGSREEFDEMIRFIEKYKIKPIIDKVYSLEEAIQALSRMEQGEQ
FGNIALRME

Sequences:

>Translated_329_residues
MKAIVHQYKKGVEGLENKFLSETHPNAGEVKVKLKAAGLNHRDLFIINNRKEMDLPLVIGSDGAGIVTEIGEGVSADLLQ
AEVIINPSIGWENIAEVPELPEVLGGPKDGTFAEYVIVPAENVVGKPSYLTWEESGVLALSALTAYRALFTKGRLKCGEH
VLIPGIGGGVATFAMLFAKAIGAKVSVTSRVENKRKFAETYGADFSFNSSGNWEESLCGGKVDLIIDSIGPATFIKYFDV
LNPNGRIVNFGASSGDKIELPLRALFYNQIDIMGTSMGSREEFDEMIRFIEKYKIKPIIDKVYSLEEAIQALSRMEQGEQ
FGNIALRME
>Mature_329_residues
MKAIVHQYKKGVEGLENKFLSETHPNAGEVKVKLKAAGLNHRDLFIINNRKEMDLPLVIGSDGAGIVTEIGEGVSADLLQ
AEVIINPSIGWENIAEVPELPEVLGGPKDGTFAEYVIVPAENVVGKPSYLTWEESGVLALSALTAYRALFTKGRLKCGEH
VLIPGIGGGVATFAMLFAKAIGAKVSVTSRVENKRKFAETYGADFSFNSSGNWEESLCGGKVDLIIDSIGPATFIKYFDV
LNPNGRIVNFGASSGDKIELPLRALFYNQIDIMGTSMGSREEFDEMIRFIEKYKIKPIIDKVYSLEEAIQALSRMEQGEQ
FGNIALRME

Specific function: Not Known; Probable Catabolic Enzyme. [C]

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=351, Percent_Identity=27.0655270655271, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI22538444, Length=351, Percent_Identity=27.0655270655271, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI18379349, Length=330, Percent_Identity=25.4545454545455, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI194239674, Length=308, Percent_Identity=26.9480519480519, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI13236495, Length=308, Percent_Identity=26.9480519480519, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI47519420, Length=349, Percent_Identity=26.647564469914, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI194239676, Length=303, Percent_Identity=24.7524752475248, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI28557745, Length=243, Percent_Identity=28.8065843621399, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1787863, Length=316, Percent_Identity=26.8987341772152, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI87081918, Length=346, Percent_Identity=23.6994219653179, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71988145, Length=318, Percent_Identity=23.8993710691824, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17507255, Length=293, Percent_Identity=27.3037542662116, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17562878, Length=330, Percent_Identity=23.6363636363636, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319621, Length=338, Percent_Identity=25.7396449704142, Blast_Score=83, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6324486, Length=325, Percent_Identity=25.5384615384615, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323961, Length=325, Percent_Identity=24.3076923076923, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6323729, Length=343, Percent_Identity=25.0728862973761, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.1

Molecular weight: Translated: 35925; Mature: 35925

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIVHQYKKGVEGLENKFLSETHPNAGEVKVKLKAAGLNHRDLFIINNRKEMDLPLVIG
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCEEEEECCCCCCCCEEEEC
SDGAGIVTEIGEGVSADLLQAEVIINPSIGWENIAEVPELPEVLGGPKDGTFAEYVIVPA
CCCCCHHHHHCCCCCHHHEEEEEEECCCCCHHHHHHCCCCHHHHCCCCCCCEEEEEEEEC
ENVVGKPSYLTWEESGVLALSALTAYRALFTKGRLKCGEHVLIPGIGGGVATFAMLFAKA
HHHCCCCCEEEECCCCEEEHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHH
IGAKVSVTSRVENKRKFAETYGADFSFNSSGNWEESLCGGKVDLIIDSIGPATFIKYFDV
HCCCEEEHHHHHHHHHHHHHHCCCEEECCCCCHHHHHCCCEEEEEEECCCHHHHHHHHHC
LNPNGRIVNFGASSGDKIELPLRALFYNQIDIMGTSMGSREEFDEMIRFIEKYKIKPIID
CCCCCCEEEECCCCCCEEECCHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHCCCCHHHH
KVYSLEEAIQALSRMEQGEQFGNIALRME
HHHHHHHHHHHHHHHHCCHHHCCEEEEEC
>Mature Secondary Structure
MKAIVHQYKKGVEGLENKFLSETHPNAGEVKVKLKAAGLNHRDLFIINNRKEMDLPLVIG
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCEEEEECCCCCCCCEEEEC
SDGAGIVTEIGEGVSADLLQAEVIINPSIGWENIAEVPELPEVLGGPKDGTFAEYVIVPA
CCCCCHHHHHCCCCCHHHEEEEEEECCCCCHHHHHHCCCCHHHHCCCCCCCEEEEEEEEC
ENVVGKPSYLTWEESGVLALSALTAYRALFTKGRLKCGEHVLIPGIGGGVATFAMLFAKA
HHHCCCCCEEEECCCCEEEHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHH
IGAKVSVTSRVENKRKFAETYGADFSFNSSGNWEESLCGGKVDLIIDSIGPATFIKYFDV
HCCCEEEHHHHHHHHHHHHHHCCCEEECCCCCHHHHHCCCEEEEEEECCCHHHHHHHHHC
LNPNGRIVNFGASSGDKIELPLRALFYNQIDIMGTSMGSREEFDEMIRFIEKYKIKPIID
CCCCCCEEEECCCCCCEEECCHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHCCCCHHHH
KVYSLEEAIQALSRMEQGEQFGNIALRME
HHHHHHHHHHHHHHHHCCHHHCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alcohol; NAD+

Specific reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]