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The map label for this gene is yxdK [H]

Identifier: 218903731

GI number: 218903731

Start: 2484328

End: 2485311

Strand: Direct

Name: yxdK [H]

Synonym: BCAH820_2615

Alternate gene names: 218903731

Gene position: 2484328-2485311 (Clockwise)

Preceding gene: 218903730

Following gene: 218903733

Centisome position: 46.85

GC content: 32.45

Gene sequence:

>984_bases
ATGATAAGGCTGTTTATACGTGATCATATACCACTTATTTGTTTTACAGCAATTCAACTACTATCCATATTTCTCGTATA
TTGGTTTGATGGGTATAACCATACTGCAACGGCATTATACGCAATGTTTTTAGGTGCCTTTTTTATGGTAGGTTATTTAA
TATTTCGTTACTTTACACATCGTTCTTTTTATGAGCGTTTAGCAAACCCGATGCAATCTTTAGATGAATCTGTTCAAAAT
TCTGATTTTGCAGCTATATCTGCTGCTCTTCAACACTTGCTTGAGGTACAATATCGCCATTATCAAAATCAGCTTCAAAT
ACAAGAGAGAAAAAATAATGATCATTTAACTTTTATGAATCAGTGGATTCATCAAATGRAAACACCTTTATCTGTCATAG
AATTAATTACACAAGATGAAGTTGATCCACGCTTCGAAAGTATAAATGAGGAAACAGATAGACTGAAAAAGGGGTTAGAG
ATGGCATTGTATGTTGCACGTTTAGAAGCATTTACACAAGATTTTTATGTAGAAAAAGTACAGCTATATAAAATAGTGAA
TGATTCTGTGCATGAACATAAACGTTTCTTTATCCGGAATTTTGTATATCCAGAGCTTAAAGTTGAGAAAGATATTACTG
TAGAAAGTGATGCGAAATGGTTACAATTTTTAATTGGACAAATACTATCGAATGCGATTAAATATTCATCTGGTAGTAGA
GAGAAGATTAAAGTGAAAGCTTGTAAGGAAGGTAATACAGTCATACTTGAAATTGCTGATAACGGTGTAGGCATACCGAA
GCAAGATTTACCAAGAGTATTTAAACCTTTCTTTACAGGAGAAAATGGCAGAGATTTTAAAGAATCAACTGGAATGGGGC
TATATCTTGTATATGAAATTACGAAACAATTAGGACATAGTGTAGAAATCCATTCAGAAGTTGGTAAAGGTACCGTTGTA
CGTATTAAATTTTTTAATGTGTAA

Upstream 100 bases:

>100_bases
TGCGAAAGAAGTTAAAAACGTTACAGATTGAGGATGCGATTGAAACAATTCGTAGTGTTGGATATAGATTGCATATTACT
TGGGATACGGGTATGGAAAA

Downstream 100 bases:

>100_bases
AAATATGTAATCTAGGCTAAAGAACTTTGGAGATAAGTTTTTTAGCCTTTTTGTATAGCGGTTATATGAAATGGCAAAAC
GTTATATTAGTATGTATAAT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MIRLFIRDHIPLICFTAIQLLSIFLVYWFDGYNHTATALYAMFLGAFFMVGYLIFRYFTHRSFYERLANPMQSLDESVQN
SDFAAISAALQHLLEVQYRHYQNQLQIQERKNNDHLTFMNQWIHQMXTPLSVIELITQDEVDPRFESINEETDRLKKGLE
MALYVARLEAFTQDFYVEKVQLYKIVNDSVHEHKRFFIRNFVYPELKVEKDITVESDAKWLQFLIGQILSNAIKYSSGSR
EKIKVKACKEGNTVILEIADNGVGIPKQDLPRVFKPFFTGENGRDFKESTGMGLYLVYEITKQLGHSVEIHSEVGKGTVV
RIKFFNV

Sequences:

>Translated_327_residues
MIRLFIRDHIPLICFTAIQLLSIFLVYWFDGYNHTATALYAMFLGAFFMVGYLIFRYFTHRSFYERLANPMQSLDESVQN
SDFAAISAALQHLLEVQYRHYQNQLQIQERKNNDHLTFMNQWIHQMXTPLSVIELITQDEVDPRFESINEETDRLKKGLE
MALYVARLEAFTQDFYVEKVQLYKIVNDSVHEHKRFFIRNFVYPELKVEKDITVESDAKWLQFLIGQILSNAIKYSSGSR
EKIKVKACKEGNTVILEIADNGVGIPKQDLPRVFKPFFTGENGRDFKESTGMGLYLVYEITKQLGHSVEIHSEVGKGTVV
RIKFFNV
>Mature_327_residues
MIRLFIRDHIPLICFTAIQLLSIFLVYWFDGYNHTATALYAMFLGAFFMVGYLIFRYFTHRSFYERLANPMQSLDESVQN
SDFAAISAALQHLLEVQYRHYQNQLQIQERKNNDHLTFMNQWIHQMXTPLSVIELITQDEVDPRFESINEETDRLKKGLE
MALYVARLEAFTQDFYVEKVQLYKIVNDSVHEHKRFFIRNFVYPELKVEKDITVESDAKWLQFLIGQILSNAIKYSSGSR
EKIKVKACKEGNTVILEIADNGVGIPKQDLPRVFKPFFTGENGRDFKESTGMGLYLVYEITKQLGHSVEIHSEVGKGTVV
RIKFFNV

Specific function: Probable member of the two-component regulatory system yxdK/yxdJ. May activate yxdJ in response to the antibacterial protein LL-37 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=240, Percent_Identity=25, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790436, Length=246, Percent_Identity=25.609756097561, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI48994928, Length=242, Percent_Identity=22.7272727272727, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467 [H]

Pfam domain/function: PF02518 HATPase_c [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 38155; Mature: 38155

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRLFIRDHIPLICFTAIQLLSIFLVYWFDGYNHTATALYAMFLGAFFMVGYLIFRYFTH
CEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSFYERLANPMQSLDESVQNSDFAAISAALQHLLEVQYRHYQNQLQIQERKNNDHLTFMN
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
QWIHQMXTPLSVIELITQDEVDPRFESINEETDRLKKGLEMALYVARLEAFTQDFYVEKV
HHHHHHHCHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLYKIVNDSVHEHKRFFIRNFVYPELKVEKDITVESDAKWLQFLIGQILSNAIKYSSGSR
HHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
EKIKVKACKEGNTVILEIADNGVGIPKQDLPRVFKPFFTGENGRDFKESTGMGLYLVYEI
CEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHH
TKQLGHSVEIHSEVGKGTVVRIKFFNV
HHHHCCCEEEHHHCCCCEEEEEEEECC
>Mature Secondary Structure
MIRLFIRDHIPLICFTAIQLLSIFLVYWFDGYNHTATALYAMFLGAFFMVGYLIFRYFTH
CEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSFYERLANPMQSLDESVQNSDFAAISAALQHLLEVQYRHYQNQLQIQERKNNDHLTFMN
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
QWIHQMXTPLSVIELITQDEVDPRFESINEETDRLKKGLEMALYVARLEAFTQDFYVEKV
HHHHHHHCHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLYKIVNDSVHEHKRFFIRNFVYPELKVEKDITVESDAKWLQFLIGQILSNAIKYSSGSR
HHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
EKIKVKACKEGNTVILEIADNGVGIPKQDLPRVFKPFFTGENGRDFKESTGMGLYLVYEI
CEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHH
TKQLGHSVEIHSEVGKGTVVRIKFFNV
HHHHCCCEEEHHHCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7952181; 9384377; 8867804 [H]