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The map label for this gene is gpmA [H]

Identifier: 218903625

GI number: 218903625

Start: 2381985

End: 2382722

Strand: Direct

Name: gpmA [H]

Synonym: BCAH820_2509

Alternate gene names: 218903625

Gene position: 2381985-2382722 (Clockwise)

Preceding gene: 218903624

Following gene: 218903627

Centisome position: 44.92

GC content: 35.37

Gene sequence:

>738_bases
ATGATAAAACTTGTACTTATTCGTCACGGACAAAGTTTATGGAATCTTGAAAATCGTTTTACTGGTTGGACTGATGTAGA
TTTATCAGAGAATGGATTAAGTGAAGCGAGAGAAGCAGGAGCGATATTAAAGAAAAATGGATATACTTTTGATGTAGCTT
ATACATCTGTATTAAAACGAGCAATTCGGACGTTATGGATTGTACTTCATGAGATGGACCTTGCATGGGTGCCAGTACAT
AAATGTTGGAAGTTAAATGAAAGACATTACGGTGCATTGCAAGGGTTGAATAAAGATGAAACTGCGAAAAAATATGGTGA
GGAGCAAGTTCATATTTGGAGAAGAAGTATTGATGTAAGACCACCTGCTCTTACTGAGGATGATCCTAGGTATGAAATGA
ATGATCTAAGATATAAAGCACTGAAAAAAGGTGAGTTTCCATTGACAGAATGTTTAGTGGATACGGAGAAAAGAGTACTT
GATTATTGGCATTCAGAAATTGCGCCGAAATTAAAGAATGGTAACAAAGTAATCATTTCATCACATGGTAACACAATTCG
CTCGCTAGTAAAATATTTAGATAATCTTTCAAGCGATGGTGTTGTTTCACTAAATATTCCAACGAGTATTCCGCTCGTGT
ATGAATTAGACGAAAATTTACGTCCGATTCGCCATTATTACTTAAGTATGGATGGAGAAGTACCTGAAGGAGAAATTCCG
AAACATATTACTTTTTAA

Upstream 100 bases:

>100_bases
AGCTATCATAGAGTGAATGGATAAAAAGATACATTACTAGATACTTTATACGTGTACGCAATGGAACAATAAAATTCACA
TTTCCGAGAGGGGAATTATT

Downstream 100 bases:

>100_bases
CATGAAAATTTGAAACGCATGCTTGTCTACATATACAATGTAGATTCAGGATAAAAGACGTGGCACCTTCTAATGTATAT
GCAATGTAGCTAAATTTAGA

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM 1; PGAM 1; Phosphoglyceromutase 1; dPGM 1 [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MIKLVLIRHGQSLWNLENRFTGWTDVDLSENGLSEAREAGAILKKNGYTFDVAYTSVLKRAIRTLWIVLHEMDLAWVPVH
KCWKLNERHYGALQGLNKDETAKKYGEEQVHIWRRSIDVRPPALTEDDPRYEMNDLRYKALKKGEFPLTECLVDTEKRVL
DYWHSEIAPKLKNGNKVIISSHGNTIRSLVKYLDNLSSDGVVSLNIPTSIPLVYELDENLRPIRHYYLSMDGEVPEGEIP
KHITF

Sequences:

>Translated_245_residues
MIKLVLIRHGQSLWNLENRFTGWTDVDLSENGLSEAREAGAILKKNGYTFDVAYTSVLKRAIRTLWIVLHEMDLAWVPVH
KCWKLNERHYGALQGLNKDETAKKYGEEQVHIWRRSIDVRPPALTEDDPRYEMNDLRYKALKKGEFPLTECLVDTEKRVL
DYWHSEIAPKLKNGNKVIISSHGNTIRSLVKYLDNLSSDGVVSLNIPTSIPLVYELDENLRPIRHYYLSMDGEVPEGEIP
KHITF
>Mature_245_residues
MIKLVLIRHGQSLWNLENRFTGWTDVDLSENGLSEAREAGAILKKNGYTFDVAYTSVLKRAIRTLWIVLHEMDLAWVPVH
KCWKLNERHYGALQGLNKDETAKKYGEEQVHIWRRSIDVRPPALTEDDPRYEMNDLRYKALKKGEFPLTECLVDTEKRVL
DYWHSEIAPKLKNGNKVIISSHGNTIRSLVKYLDNLSSDGVVSLNIPTSIPLVYELDENLRPIRHYYLSMDGEVPEGEIP
KHITF

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=234, Percent_Identity=50.4273504273504, Blast_Score=256, Evalue=1e-68,
Organism=Homo sapiens, GI4505753, Length=234, Percent_Identity=53.8461538461538, Blast_Score=252, Evalue=2e-67,
Organism=Homo sapiens, GI71274132, Length=234, Percent_Identity=51.2820512820513, Blast_Score=237, Evalue=6e-63,
Organism=Homo sapiens, GI4502445, Length=243, Percent_Identity=44.0329218106996, Blast_Score=228, Evalue=4e-60,
Organism=Homo sapiens, GI40353764, Length=243, Percent_Identity=44.0329218106996, Blast_Score=228, Evalue=4e-60,
Organism=Homo sapiens, GI310129614, Length=160, Percent_Identity=57.5, Blast_Score=172, Evalue=3e-43,
Organism=Escherichia coli, GI1786970, Length=234, Percent_Identity=62.3931623931624, Blast_Score=312, Evalue=2e-86,
Organism=Saccharomyces cerevisiae, GI6322697, Length=229, Percent_Identity=51.0917030567686, Blast_Score=229, Evalue=4e-61,
Organism=Saccharomyces cerevisiae, GI6324516, Length=279, Percent_Identity=31.5412186379928, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6320183, Length=285, Percent_Identity=30.1754385964912, Blast_Score=112, Evalue=7e-26,
Organism=Drosophila melanogaster, GI85725270, Length=224, Percent_Identity=51.7857142857143, Blast_Score=228, Evalue=2e-60,
Organism=Drosophila melanogaster, GI85725272, Length=224, Percent_Identity=51.7857142857143, Blast_Score=228, Evalue=2e-60,
Organism=Drosophila melanogaster, GI24650981, Length=224, Percent_Identity=51.7857142857143, Blast_Score=228, Evalue=2e-60,
Organism=Drosophila melanogaster, GI24646216, Length=224, Percent_Identity=50.8928571428571, Blast_Score=227, Evalue=6e-60,
Organism=Drosophila melanogaster, GI28571815, Length=218, Percent_Identity=38.9908256880734, Blast_Score=166, Evalue=9e-42,
Organism=Drosophila melanogaster, GI28571817, Length=218, Percent_Identity=38.9908256880734, Blast_Score=166, Evalue=9e-42,
Organism=Drosophila melanogaster, GI24648979, Length=218, Percent_Identity=38.9908256880734, Blast_Score=166, Evalue=1e-41,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 28356; Mature: 28356

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKLVLIRHGQSLWNLENRFTGWTDVDLSENGLSEAREAGAILKKNGYTFDVAYTSVLKR
CEEEEEEECCCHHHHHHHHCCCCEECCCCCCCHHHHHHCCCEEECCCCEEEHHHHHHHHH
AIRTLWIVLHEMDLAWVPVHKCWKLNERHYGALQGLNKDETAKKYGEEQVHIWRRSIDVR
HHHHHHHHHHHCCCEEECHHHHHHCCCCHHHHHCCCCCCHHHHHHCCHHHHHHHHHCCCC
PPALTEDDPRYEMNDLRYKALKKGEFPLTECLVDTEKRVLDYWHSEIAPKLKNGNKVIIS
CCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCHHHCCCCEEEEE
SHGNTIRSLVKYLDNLSSDGVVSLNIPTSIPLVYELDENLRPIRHYYLSMDGEVPEGEIP
CCCHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCCCCHHHHHEEECCCCCCCCCCC
KHITF
CCCCC
>Mature Secondary Structure
MIKLVLIRHGQSLWNLENRFTGWTDVDLSENGLSEAREAGAILKKNGYTFDVAYTSVLKR
CEEEEEEECCCHHHHHHHHCCCCEECCCCCCCHHHHHHCCCEEECCCCEEEHHHHHHHHH
AIRTLWIVLHEMDLAWVPVHKCWKLNERHYGALQGLNKDETAKKYGEEQVHIWRRSIDVR
HHHHHHHHHHHCCCEEECHHHHHHCCCCHHHHHCCCCCCHHHHHHCCHHHHHHHHHCCCC
PPALTEDDPRYEMNDLRYKALKKGEFPLTECLVDTEKRVLDYWHSEIAPKLKNGNKVIIS
CCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCHHHCCCCEEEEE
SHGNTIRSLVKYLDNLSSDGVVSLNIPTSIPLVYELDENLRPIRHYYLSMDGEVPEGEIP
CCCHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCCCCHHHHHEEECCCCCCCCCCC
KHITF
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA