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The map label for this gene is bacB [H]

Identifier: 218903505

GI number: 218903505

Start: 2269542

End: 2270429

Strand: Direct

Name: bacB [H]

Synonym: BCAH820_2389

Alternate gene names: 218903505

Gene position: 2269542-2270429 (Clockwise)

Preceding gene: 218903504

Following gene: 218903506

Centisome position: 42.8

GC content: 35.47

Gene sequence:

>888_bases
ATGGCTATTCCATCTATTTCAGTATACAAAATGCCAATTGAATCAGAACTACCAAAAAATAAAGTGAATTGGACACCAGA
TCCGAAACGTGCAGTTCTTTTAATTCATGACATGCAAGAATATTTCCTTGATGCATATAGCGATAAAGAATCACCAAAAG
TAGAACTTATTTCAAATATTAAAATGATAAGAGAAAAATGTAATAATCTTGGTATACCAGTTGTTTATACAGCACAGCCA
GGTGGACAAACGTTAGAACAACGAGGGTTATTACAAGACTTCTGGGGTGACGGTATTCCTGCTGGACCAGATAAAAAGAA
GATTGTCGATGAACTTACTCCTAATGAGGATGATATATTCTTAACAAAATGGAGATATAGTGCATTTAAAAAGACAAATC
TATTAGAAATTTTAAATGAACAGGGAAGAGATCAACTCATTATTTGCGGTATTTATGCGCATATTGGCTGCCTTTTAACA
GCTTGTGAAGCATTTATGGATGGAATTCAGCCGTTCTTTGTAGCAGATGCAGTTGCTGATTTTTCACTAGAACATCATAA
ACAAGCGTTGGAGTATGCGTCAAATAGATGTGCAGTAACGACATCAACTAACAGTTTGTTAACAGAGTTACAAGGTTTAA
AAGATGATGATGAAATCACTTTACAAAAAGTACATGAACTAGTTGCACAATTACTTCGTGAACCAGTAGAGAGTGTTGGG
ACTGATGAAGATTTATTAAATAGAGGACTTGATTCGGTCAGAATTATGAGTTTAGTAGAGAAGTGGCGTCGCGAAGGGAA
AGAAATCACTTTTGCGGATTTAGCAGAGAACCCAACGGTTGTTGATTGGTATCGCTTATTATCTCTGCAAACAGAACATG
TACTTTAA

Upstream 100 bases:

>100_bases
AACAGGAGTCGGAAAAGTCAGTAAAAAAGAGCTACGTAAAGTCATTGCTGAAAAACTTATTACAGTAAAACAATAATAAA
AACCGGAAGGAAGTGATTAG

Downstream 100 bases:

>100_bases
TATAGACTACATAATAAAGGGGTAGTAAAGAATGCCTAATAGTCAAAAGGTTCGTCATTCGTTATCATCTGCGCAGTCTG
GTATGTGGTTTGCGCAACAA

Product: isochorismatase

Products: NA

Alternate protein names: 2,3 dihydro-2,3 dihydroxybenzoate synthase; Superoxide-inducible protein 1; SOI1 [H]

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MAIPSISVYKMPIESELPKNKVNWTPDPKRAVLLIHDMQEYFLDAYSDKESPKVELISNIKMIREKCNNLGIPVVYTAQP
GGQTLEQRGLLQDFWGDGIPAGPDKKKIVDELTPNEDDIFLTKWRYSAFKKTNLLEILNEQGRDQLIICGIYAHIGCLLT
ACEAFMDGIQPFFVADAVADFSLEHHKQALEYASNRCAVTTSTNSLLTELQGLKDDDEITLQKVHELVAQLLREPVESVG
TDEDLLNRGLDSVRIMSLVEKWRREGKEITFADLAENPTVVDWYRLLSLQTEHVL

Sequences:

>Translated_295_residues
MAIPSISVYKMPIESELPKNKVNWTPDPKRAVLLIHDMQEYFLDAYSDKESPKVELISNIKMIREKCNNLGIPVVYTAQP
GGQTLEQRGLLQDFWGDGIPAGPDKKKIVDELTPNEDDIFLTKWRYSAFKKTNLLEILNEQGRDQLIICGIYAHIGCLLT
ACEAFMDGIQPFFVADAVADFSLEHHKQALEYASNRCAVTTSTNSLLTELQGLKDDDEITLQKVHELVAQLLREPVESVG
TDEDLLNRGLDSVRIMSLVEKWRREGKEITFADLAENPTVVDWYRLLSLQTEHVL
>Mature_294_residues
AIPSISVYKMPIESELPKNKVNWTPDPKRAVLLIHDMQEYFLDAYSDKESPKVELISNIKMIREKCNNLGIPVVYTAQPG
GQTLEQRGLLQDFWGDGIPAGPDKKKIVDELTPNEDDIFLTKWRYSAFKKTNLLEILNEQGRDQLIICGIYAHIGCLLTA
CEAFMDGIQPFFVADAVADFSLEHHKQALEYASNRCAVTTSTNSLLTELQGLKDDDEITLQKVHELVAQLLREPVESVGT
DEDLLNRGLDSVRIMSLVEKWRREGKEITFADLAENPTVVDWYRLLSLQTEHVL

Specific function: Required For Production Of 2,3-Dhb. Also Serves As An Aryl Carrier Protein And Plays A Role In Enterobactin Assembly. [C]

COG id: COG1535

COG function: function code Q; Isochorismate hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Escherichia coli, GI1786811, Length=294, Percent_Identity=44.5578231292517, Blast_Score=263, Evalue=1e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009081
- InterPro:   IPR016291
- InterPro:   IPR000868
- InterPro:   IPR006163 [H]

Pfam domain/function: PF00857 Isochorismatase; PF00550 PP-binding [H]

EC number: =3.3.2.1 [H]

Molecular weight: Translated: 33449; Mature: 33317

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS50075 ACP_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIPSISVYKMPIESELPKNKVNWTPDPKRAVLLIHDMQEYFLDAYSDKESPKVELISNI
CCCCCCEEEECCCHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCHHHHHHHH
KMIREKCNNLGIPVVYTAQPGGQTLEQRGLLQDFWGDGIPAGPDKKKIVDELTPNEDDIF
HHHHHHHHCCCCCEEEECCCCCHHHHHCCCHHHHCCCCCCCCCCHHHHHHHCCCCCCCEE
LTKWRYSAFKKTNLLEILNEQGRDQLIICGIYAHIGCLLTACEAFMDGIQPFFVADAVAD
EEEHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
FSLEHHKQALEYASNRCAVTTSTNSLLTELQGLKDDDEITLQKVHELVAQLLREPVESVG
HHHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
TDEDLLNRGLDSVRIMSLVEKWRREGKEITFADLAENPTVVDWYRLLSLQTEHVL
CCHHHHHCCHHHHHHHHHHHHHHHCCCCEEEHHHCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AIPSISVYKMPIESELPKNKVNWTPDPKRAVLLIHDMQEYFLDAYSDKESPKVELISNI
CCCCCEEEECCCHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCHHHHHHHH
KMIREKCNNLGIPVVYTAQPGGQTLEQRGLLQDFWGDGIPAGPDKKKIVDELTPNEDDIF
HHHHHHHHCCCCCEEEECCCCCHHHHHCCCHHHHCCCCCCCCCCHHHHHHHCCCCCCCEE
LTKWRYSAFKKTNLLEILNEQGRDQLIICGIYAHIGCLLTACEAFMDGIQPFFVADAVAD
EEEHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
FSLEHHKQALEYASNRCAVTTSTNSLLTELQGLKDDDEITLQKVHELVAQLLREPVESVG
HHHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
TDEDLLNRGLDSVRIMSLVEKWRREGKEITFADLAENPTVVDWYRLLSLQTEHVL
CCHHHHHCCHHHHHHHHHHHHHHHCCCCEEEHHHCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550523; 9384377; 9298659 [H]