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The map label for this gene is bacC [H]

Identifier: 218903503

GI number: 218903503

Start: 2266689

End: 2267888

Strand: Direct

Name: bacC [H]

Synonym: BCAH820_2387

Alternate gene names: 218903503

Gene position: 2266689-2267888 (Clockwise)

Preceding gene: 218903502

Following gene: 218903504

Centisome position: 42.75

GC content: 38.42

Gene sequence:

>1200_bases
ATGAATGAATTTACGGCTGTAAAGGAACTGTCAGAAAAATTACTAGAAGATTATAAGACTGAATCTTCATTCTTTTTTGC
TTCACCAACCCGAACGATATTAGCAGAAGGAGAATTTACTACAGTAAAGCATCATGAAATTGAAAGCTTCCCAGAGCTTG
TGCAAGCAGTATTACGTAATGCAAAACAAGCCGGAAATCCGAATCCTATCGTTGTGGGGGCTTTGCCATTTGATCGTAGA
AAAGAAGTCCAACTTATCGTACCAGAATATAGCAGGATTTCTGAGCGTTTACAATTGGATACAACAAATCATCTTGAAAT
AAATAGGAACTTAACATTCGAAATGACGCCTGTGCCAGATCATGAAGTGTATATGAATGGTGTGAAGCAAGGGATCAAAA
AAATACAGGACGGGGATTTAAAGAAAATCGTTCTATCTAGATCGTTAGATGTTAAATCTTCTGAAAAGATTGATAAGAAA
AAACTTCTTCGAGAATTAGCAGAGCATAATAAGCACGGTTATACATTTGCGGTGAATTTACCGAAAGATGAAAACGAGAA
TAGTAAGACGTTAATTGGAGCTAGTCCTGAATTACTCGTTTCACGTCATGGTATGCAAGTGATTTCTAATCCGTTAGCTG
GTTCAAGACCACGTAGTGATGATCCAGTAGAAGATAAAAGAAGAGCGGAGGAATTACTTTCTTCTCCAAAAGATTTGCAT
GAACATGCGGTAGTAGTGGAAGCAGTTGCTGCTGCGCTTCGCCCATACTGTCATACATTACATGTTCCGGAAAAACCATC
TGTTATTCATAGTGAAGCGATGTGGCATTTGTCTACTGAAGTGAAAGGTGAACTAAAGAATCCAAATACTAGTTCTTTAG
AATTAGCAATTGCTCTTCATCCTACGCCAGCAGTTTGCGGAACGCCGATGGAAGAAGCGAGAGAAGCTATTCAACAAATT
GAGCCATTTGACCGTGAGTTCTTTACAGGAATGTTAGGGTGGAGCGATTTAAATGGAGACGGTGAATGGATTGTTACAAT
TCGTTGTGCTGAAGTACAAGAAAATACACTCCGTTTATATGCAGGTGCTGGAGTTGTTGCTGAGTCAAAACCAGAAGATG
AATTAGCAGAAACATCAGCTAAGTTTCAAACAATGTTGAAAGCTTTAGGGTTAAATGATAGTTCACTTAATGAAAAGTAG

Upstream 100 bases:

>100_bases
TAGCTTCAGATAAAGCGAGTCATATTACAATGCACAATTTATGTGTCGATGGCGGAGCTACATTAGGAGTTTAATAAAAA
ATTTAGGGGGCTACTATACT

Downstream 100 bases:

>100_bases
GGGGCAGAAAGAATGTTAACAGGTTATACAAAATGGCCAAAAGAATTTGCCGATCGCTATCGAGAGGAAGGGTGTTGGCT
TGGGGAAACATTTGGCGGAG

Product: isochorismate synthase DhbC

Products: NA

Alternate protein names: Isochorismate mutase [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MNEFTAVKELSEKLLEDYKTESSFFFASPTRTILAEGEFTTVKHHEIESFPELVQAVLRNAKQAGNPNPIVVGALPFDRR
KEVQLIVPEYSRISERLQLDTTNHLEINRNLTFEMTPVPDHEVYMNGVKQGIKKIQDGDLKKIVLSRSLDVKSSEKIDKK
KLLRELAEHNKHGYTFAVNLPKDENENSKTLIGASPELLVSRHGMQVISNPLAGSRPRSDDPVEDKRRAEELLSSPKDLH
EHAVVVEAVAAALRPYCHTLHVPEKPSVIHSEAMWHLSTEVKGELKNPNTSSLELAIALHPTPAVCGTPMEEAREAIQQI
EPFDREFFTGMLGWSDLNGDGEWIVTIRCAEVQENTLRLYAGAGVVAESKPEDELAETSAKFQTMLKALGLNDSSLNEK

Sequences:

>Translated_399_residues
MNEFTAVKELSEKLLEDYKTESSFFFASPTRTILAEGEFTTVKHHEIESFPELVQAVLRNAKQAGNPNPIVVGALPFDRR
KEVQLIVPEYSRISERLQLDTTNHLEINRNLTFEMTPVPDHEVYMNGVKQGIKKIQDGDLKKIVLSRSLDVKSSEKIDKK
KLLRELAEHNKHGYTFAVNLPKDENENSKTLIGASPELLVSRHGMQVISNPLAGSRPRSDDPVEDKRRAEELLSSPKDLH
EHAVVVEAVAAALRPYCHTLHVPEKPSVIHSEAMWHLSTEVKGELKNPNTSSLELAIALHPTPAVCGTPMEEAREAIQQI
EPFDREFFTGMLGWSDLNGDGEWIVTIRCAEVQENTLRLYAGAGVVAESKPEDELAETSAKFQTMLKALGLNDSSLNEK
>Mature_399_residues
MNEFTAVKELSEKLLEDYKTESSFFFASPTRTILAEGEFTTVKHHEIESFPELVQAVLRNAKQAGNPNPIVVGALPFDRR
KEVQLIVPEYSRISERLQLDTTNHLEINRNLTFEMTPVPDHEVYMNGVKQGIKKIQDGDLKKIVLSRSLDVKSSEKIDKK
KLLRELAEHNKHGYTFAVNLPKDENENSKTLIGASPELLVSRHGMQVISNPLAGSRPRSDDPVEDKRRAEELLSSPKDLH
EHAVVVEAVAAALRPYCHTLHVPEKPSVIHSEAMWHLSTEVKGELKNPNTSSLELAIALHPTPAVCGTPMEEAREAIQQI
EPFDREFFTGMLGWSDLNGDGEWIVTIRCAEVQENTLRLYAGAGVVAESKPEDELAETSAKFQTMLKALGLNDSSLNEK

Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]

COG id: COG1169

COG function: function code HQ; Isochorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isochorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786809, Length=377, Percent_Identity=37.9310344827586, Blast_Score=258, Evalue=5e-70,
Organism=Escherichia coli, GI87082077, Length=275, Percent_Identity=30.1818181818182, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787518, Length=268, Percent_Identity=28.3582089552239, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788114, Length=277, Percent_Identity=25.9927797833935, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320935, Length=280, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR015890
- InterPro:   IPR004561 [H]

Pfam domain/function: PF00425 Chorismate_bind [H]

EC number: =5.4.4.2 [H]

Molecular weight: Translated: 44628; Mature: 44628

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEFTAVKELSEKLLEDYKTESSFFFASPTRTILAEGEFTTVKHHEIESFPELVQAVLRN
CCCHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCEEEEEHHHHHHHHHHHHHHHHH
AKQAGNPNPIVVGALPFDRRKEVQLIVPEYSRISERLQLDTTNHLEINRNLTFEMTPVPD
HHHCCCCCCEEEECCCCCCCCCEEEECCCHHHHHHHHCCCCCCCEEECCCEEEEECCCCC
HEVYMNGVKQGIKKIQDGDLKKIVLSRSLDVKSSEKIDKKKLLRELAEHNKHGYTFAVNL
HHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEC
PKDENENSKTLIGASPELLVSRHGMQVISNPLAGSRPRSDDPVEDKRRAEELLSSPKDLH
CCCCCCCCCEEECCCHHHHHHHCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHH
EHAVVVEAVAAALRPYCHTLHVPEKPSVIHSEAMWHLSTEVKGELKNPNTSSLELAIALH
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHCCCCCCCCCCCEEEEEEEC
PTPAVCGTPMEEAREAIQQIEPFDREFFTGMLGWSDLNGDGEWIVTIRCAEVQENTLRLY
CCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEEEE
AGAGVVAESKPEDELAETSAKFQTMLKALGLNDSSLNEK
ECCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNEFTAVKELSEKLLEDYKTESSFFFASPTRTILAEGEFTTVKHHEIESFPELVQAVLRN
CCCHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCEEEEEHHHHHHHHHHHHHHHHH
AKQAGNPNPIVVGALPFDRRKEVQLIVPEYSRISERLQLDTTNHLEINRNLTFEMTPVPD
HHHCCCCCCEEEECCCCCCCCCEEEECCCHHHHHHHHCCCCCCCEEECCCEEEEECCCCC
HEVYMNGVKQGIKKIQDGDLKKIVLSRSLDVKSSEKIDKKKLLRELAEHNKHGYTFAVNL
HHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEC
PKDENENSKTLIGASPELLVSRHGMQVISNPLAGSRPRSDDPVEDKRRAEELLSSPKDLH
CCCCCCCCCEEECCCHHHHHHHCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHH
EHAVVVEAVAAALRPYCHTLHVPEKPSVIHSEAMWHLSTEVKGELKNPNTSSLELAIALH
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHCCCCCCCCCCCEEEEEEEC
PTPAVCGTPMEEAREAIQQIEPFDREFFTGMLGWSDLNGDGEWIVTIRCAEVQENTLRLY
CCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEEEE
AGAGVVAESKPEDELAETSAKFQTMLKALGLNDSSLNEK
ECCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550523; 9384377 [H]