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The map label for this gene is gmhB [H]

Identifier: 218903370

GI number: 218903370

Start: 2143675

End: 2144202

Strand: Reverse

Name: gmhB [H]

Synonym: BCAH820_2254

Alternate gene names: 218903370

Gene position: 2144202-2143675 (Counterclockwise)

Preceding gene: 218903371

Following gene: 218903363

Centisome position: 40.44

GC content: 38.26

Gene sequence:

>528_bases
ATGGCAAACATTCAAGCAATTTTCATTGATCGTGACGGTACAATTGGCGGCGACACTACAATACATTATCCAGGATCATT
TACATTATTTCCTTTTACAAAAGCATCACTGCAAAAATTAAAAGCTAATCATATAAAAATTTTCTCTTTCACAAATCAAC
CAGGTATCGCGGATGAGATAGCGACTATAGCCGATTTTTCACAAGAATTAAAAAGCTTCGGTTTTGATGATATTTACGTA
TGTCCTCACAAACACAGTGATGGTTGTGAATGCCGGAAACCAAGTACAGGTATGCTTCTACAAGCAGCGGAAAAACATGG
GCTTGATTTAACACAATGTGCTGTAATTGGTGATCGCTGGACTGATATTGTTGCGGGAGCAAAAGTGAATGCGACAACAA
TTTTAGTACGAACAGGCGCTGGATACGACGCTTTACATACGTACCGAGACAAGTGGGCACATATTGAACCAAACTACATT
GCAGAAAACTTTGAAGATGCGACAAATTGGGTTTTAAATCAACTATAA

Upstream 100 bases:

>100_bases
TAGAAGCTCATCCTTTTTACAAAAAATTAGGATATGAAGTAAATGGCTATCGATTTGTAAAACATTTTTAAACTACTTTT
TAATGGAAAGGACTATAACT

Downstream 100 bases:

>100_bases
TGCTAATTAAAAGAGACGCCTTCAAAATGAAAGCGCCTCTTTTAATCTATTATTATTTAAAACGTTAATTCATAATGGAA
ATAACGATTATCTCTCAAAT

Product: hypothetical protein

Products: L-histidinol; phosphate

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MANIQAIFIDRDGTIGGDTTIHYPGSFTLFPFTKASLQKLKANHIKIFSFTNQPGIADEIATIADFSQELKSFGFDDIYV
CPHKHSDGCECRKPSTGMLLQAAEKHGLDLTQCAVIGDRWTDIVAGAKVNATTILVRTGAGYDALHTYRDKWAHIEPNYI
AENFEDATNWVLNQL

Sequences:

>Translated_175_residues
MANIQAIFIDRDGTIGGDTTIHYPGSFTLFPFTKASLQKLKANHIKIFSFTNQPGIADEIATIADFSQELKSFGFDDIYV
CPHKHSDGCECRKPSTGMLLQAAEKHGLDLTQCAVIGDRWTDIVAGAKVNATTILVRTGAGYDALHTYRDKWAHIEPNYI
AENFEDATNWVLNQL
>Mature_174_residues
ANIQAIFIDRDGTIGGDTTIHYPGSFTLFPFTKASLQKLKANHIKIFSFTNQPGIADEIATIADFSQELKSFGFDDIYVC
PHKHSDGCECRKPSTGMLLQAAEKHGLDLTQCAVIGDRWTDIVAGAKVNATTILVRTGAGYDALHTYRDKWAHIEPNYIA
ENFEDATNWVLNQL

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=192, Percent_Identity=31.25, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI87082027, Length=192, Percent_Identity=29.6875, Blast_Score=71, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: 3.1.3.15

Molecular weight: Translated: 19380; Mature: 19249

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANIQAIFIDRDGTIGGDTTIHYPGSFTLFPFTKASLQKLKANHIKIFSFTNQPGIADEI
CCCEEEEEEECCCCCCCCCEEEECCCEEEECCCHHHHHHHCCCEEEEEEECCCCCCHHHH
ATIADFSQELKSFGFDDIYVCPHKHSDGCECRKPSTGMLLQAAEKHGLDLTQCAVIGDRW
HHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCEEEEHHHCCCCHHHHEEECCCH
TDIVAGAKVNATTILVRTGAGYDALHTYRDKWAHIEPNYIAENFEDATNWVLNQL
HHHHCCCEECEEEEEEEECCCCHHHHHHHHCCCCCCCCHHHHCHHHHHHHHHHCC
>Mature Secondary Structure 
ANIQAIFIDRDGTIGGDTTIHYPGSFTLFPFTKASLQKLKANHIKIFSFTNQPGIADEI
CCEEEEEEECCCCCCCCCEEEECCCEEEECCCHHHHHHHCCCEEEEEEECCCCCCHHHH
ATIADFSQELKSFGFDDIYVCPHKHSDGCECRKPSTGMLLQAAEKHGLDLTQCAVIGDRW
HHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCEEEEHHHCCCCHHHHEEECCCH
TDIVAGAKVNATTILVRTGAGYDALHTYRDKWAHIEPNYIAENFEDATNWVLNQL
HHHHCCCEECEEEEEEEECCCCHHHHHHHHCCCCCCCCHHHHCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-histidinol phosphate; H2O

Specific reaction: L-histidinol phosphate + H2O = L-histidinol + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 12101286 [H]