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The map label for this gene is citT [C]

Identifier: 218903355

GI number: 218903355

Start: 2128722

End: 2130143

Strand: Direct

Name: citT [C]

Synonym: BCAH820_2239

Alternate gene names: 218903355

Gene position: 2128722-2130143 (Clockwise)

Preceding gene: 218903354

Following gene: 218903356

Centisome position: 40.14

GC content: 32.07

Gene sequence:

>1422_bases
ATGATTGAAAAAAATGTAGTGGAATTACATGTGGATAATAATGATACTCCGAAAGTTAAGTCATCCTGGGTTCTGCCCGT
AGCGCTTATATTAATTGTAGAAATAGTTCTTTTGCTTCCATCATCATTAACGATGGAAGCAAAATGGAGTTTGTTTGGAT
TTTGTTCTGCAATTATATTATGGACAACAACAACGATAAATTCGGCCTATATTGCACTCGGTTCTGTATTATTTCTAATT
ATTTCAGGAACAGCAAAGCAAGATCTTTTATTTGATTCGCTAGCTTCGGATGTCATTTGGCTTATGATCGGTTCGTTTAT
TTTAGGAAGAGCACTTCAAATTACCGGTCTAGCTGAAAAAATGACGTACTTTGTTGTGAATCGTGCTCGTAATATATCAG
GATTATGCTGGATTTTAACAATGATTATTCAAATACTTGCCTTTTTTATTCCATCTACATCGGGACGCGCAGCGGTTGTA
TTACCTGTTTTTCAAGCTATATGTAAAGAAATTGGAAGTAGAAGAATTACGAAAGCATTAGCAATTTTAATGCCTACTGT
GATTTTAGTTTCAACAAGTTCTACAATTATTGGGGCAGGCTCACATTTAATCGCTCTAGATATGTTAAAGGAATTTAATA
ATAAAAACATTACATTTGTAGAGTGGTTAATATGGGGATTACCATTTGGAAGTATAATGAGCTTTATAAGTTGTCGCGTA
ATATTAGTACTATTTTTAGACAAAGAGGAAGTAAAAACGAAACTGCAACAGAAAAAAGTTAAGTTTGAATTATCACGAAA
TGAAAAGTATACAATAAGCATTTTAATAGCGATGGTAGCATTTTGGCTAACGGAATGGTTACACGGTTTGGAAATTGCAA
CTGTAACTATAATAGGAGTATTTTTATTAACTTTACCAAAACTCGGTGTGATGCAGTGGAAAGAAAGTTTAAAAGGTGTC
TCTTGGAATTTAATTTTATTTGTTGGAGCGGCAATTGCATTAGGGAAATCATTAATGGAAAGCGGTGCAGCGCAATGGAT
TATGCAGAATTTATTTTTAGTAACAGAATTAATTAATAAGCAATCCATTTTCATCGTAATTGTTATCCTTTCAGTTACAT
CACATTTATATATTACATCTCACACTACGAGAGCAGTAATTTTTATTCCACCACTACTATACTTTGCAAGTAGTCTGCAA
TTAAATGAAGTAGCTGTCTTATTTTTAGGTATTGTTGGAATGAATTATTGTTTAACCTTTCCGGTCAGTTCTAAAGCACT
ACTATTATTTCAAGAAAGTGATAGAGAAACTTTTCAACCGCAAGATTTATTAAAATTAAGTAGTTATTTAAGTGTTATTT
ATATATTTGTAATGGTCATATTTTACTATGCATATTGGCAATGGGTTGGATTATCTCTTTAA

Upstream 100 bases:

>100_bases
ATGCGGAGAAATGGCTTCGTGATTGTACAGAGAGTACGATGCGTACAGTTTTAGTTGGCTATCAAATCGCTTCTCGTTTA
AATAAAAGTGGGTACGTATC

Downstream 100 bases:

>100_bases
AAATCAGGMATATATTTCATTCCTGATTTTTTTCATTAAGGATAAAACATATTGGGTATTTTTTCTTTTGAAGGAAAGTA
TTACTTGTTATACTAAAATG

Product: sodium/solute symporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MIEKNVVELHVDNNDTPKVKSSWVLPVALILIVEIVLLLPSSLTMEAKWSLFGFCSAIILWTTTTINSAYIALGSVLFLI
ISGTAKQDLLFDSLASDVIWLMIGSFILGRALQITGLAEKMTYFVVNRARNISGLCWILTMIIQILAFFIPSTSGRAAVV
LPVFQAICKEIGSRRITKALAILMPTVILVSTSSTIIGAGSHLIALDMLKEFNNKNITFVEWLIWGLPFGSIMSFISCRV
ILVLFLDKEEVKTKLQQKKVKFELSRNEKYTISILIAMVAFWLTEWLHGLEIATVTIIGVFLLTLPKLGVMQWKESLKGV
SWNLILFVGAAIALGKSLMESGAAQWIMQNLFLVTELINKQSIFIVIVILSVTSHLYITSHTTRAVIFIPPLLYFASSLQ
LNEVAVLFLGIVGMNYCLTFPVSSKALLLFQESDRETFQPQDLLKLSSYLSVIYIFVMVIFYYAYWQWVGLSL

Sequences:

>Translated_473_residues
MIEKNVVELHVDNNDTPKVKSSWVLPVALILIVEIVLLLPSSLTMEAKWSLFGFCSAIILWTTTTINSAYIALGSVLFLI
ISGTAKQDLLFDSLASDVIWLMIGSFILGRALQITGLAEKMTYFVVNRARNISGLCWILTMIIQILAFFIPSTSGRAAVV
LPVFQAICKEIGSRRITKALAILMPTVILVSTSSTIIGAGSHLIALDMLKEFNNKNITFVEWLIWGLPFGSIMSFISCRV
ILVLFLDKEEVKTKLQQKKVKFELSRNEKYTISILIAMVAFWLTEWLHGLEIATVTIIGVFLLTLPKLGVMQWKESLKGV
SWNLILFVGAAIALGKSLMESGAAQWIMQNLFLVTELINKQSIFIVIVILSVTSHLYITSHTTRAVIFIPPLLYFASSLQ
LNEVAVLFLGIVGMNYCLTFPVSSKALLLFQESDRETFQPQDLLKLSSYLSVIYIFVMVIFYYAYWQWVGLSL
>Mature_473_residues
MIEKNVVELHVDNNDTPKVKSSWVLPVALILIVEIVLLLPSSLTMEAKWSLFGFCSAIILWTTTTINSAYIALGSVLFLI
ISGTAKQDLLFDSLASDVIWLMIGSFILGRALQITGLAEKMTYFVVNRARNISGLCWILTMIIQILAFFIPSTSGRAAVV
LPVFQAICKEIGSRRITKALAILMPTVILVSTSSTIIGAGSHLIALDMLKEFNNKNITFVEWLIWGLPFGSIMSFISCRV
ILVLFLDKEEVKTKLQQKKVKFELSRNEKYTISILIAMVAFWLTEWLHGLEIATVTIIGVFLLTLPKLGVMQWKESLKGV
SWNLILFVGAAIALGKSLMESGAAQWIMQNLFLVTELINKQSIFIVIVILSVTSHLYITSHTTRAVIFIPPLLYFASSLQ
LNEVAVLFLGIVGMNYCLTFPVSSKALLLFQESDRETFQPQDLLKLSSYLSVIYIFVMVIFYYAYWQWVGLSL

Specific function: Responsible For The Uptake Of Citrate In Exchange To The Efflux Of Succinate. Has A Relatively Broad Specificity For C(4)- Dicarboxylates And Tricarboxylates. [C]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. SODIT1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI301069349, Length=301, Percent_Identity=23.5880398671096, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1786829, Length=385, Percent_Identity=23.6363636363636, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1786986, Length=349, Percent_Identity=24.6418338108883, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 52949; Mature: 52949

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEKNVVELHVDNNDTPKVKSSWVLPVALILIVEIVLLLPSSLTMEAKWSLFGFCSAIIL
CCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
WTTTTINSAYIALGSVLFLIISGTAKQDLLFDSLASDVIWLMIGSFILGRALQITGLAEK
HHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
MTYFVVNRARNISGLCWILTMIIQILAFFIPSTSGRAAVVLPVFQAICKEIGSRRITKAL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
AILMPTVILVSTSSTIIGAGSHLIALDMLKEFNNKNITFVEWLIWGLPFGSIMSFISCRV
HHHHHHHHEEECCCCEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHH
ILVLFLDKEEVKTKLQQKKVKFELSRNEKYTISILIAMVAFWLTEWLHGLEIATVTIIGV
HHHHHCCHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLLTLPKLGVMQWKESLKGVSWNLILFVGAAIALGKSLMESGAAQWIMQNLFLVTELINK
HHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QSIFIVIVILSVTSHLYITSHTTRAVIFIPPLLYFASSLQLNEVAVLFLGIVGMNYCLTF
CCHHHHHEEHHHHCCEEEEECCCEEEEEECHHHHHHCCCCHHHHHHHHHHHHHHHHEEEC
PVSSKALLLFQESDRETFQPQDLLKLSSYLSVIYIFVMVIFYYAYWQWVGLSL
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIEKNVVELHVDNNDTPKVKSSWVLPVALILIVEIVLLLPSSLTMEAKWSLFGFCSAIIL
CCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
WTTTTINSAYIALGSVLFLIISGTAKQDLLFDSLASDVIWLMIGSFILGRALQITGLAEK
HHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
MTYFVVNRARNISGLCWILTMIIQILAFFIPSTSGRAAVVLPVFQAICKEIGSRRITKAL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
AILMPTVILVSTSSTIIGAGSHLIALDMLKEFNNKNITFVEWLIWGLPFGSIMSFISCRV
HHHHHHHHEEECCCCEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHH
ILVLFLDKEEVKTKLQQKKVKFELSRNEKYTISILIAMVAFWLTEWLHGLEIATVTIIGV
HHHHHCCHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLLTLPKLGVMQWKESLKGVSWNLILFVGAAIALGKSLMESGAAQWIMQNLFLVTELINK
HHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QSIFIVIVILSVTSHLYITSHTTRAVIFIPPLLYFASSLQLNEVAVLFLGIVGMNYCLTF
CCHHHHHEEHHHHCCEEEEECCCEEEEEECHHHHHHCCCCHHHHHHHHHHHHHHHHEEEC
PVSSKALLLFQESDRETFQPQDLLKLSSYLSVIYIFVMVIFYYAYWQWVGLSL
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8405966 [H]