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The map label for this gene is cisA [H]

Identifier: 218903338

GI number: 218903338

Start: 2116496

End: 2117281

Strand: Direct

Name: cisA [H]

Synonym: BCAH820_2222

Alternate gene names: 218903338

Gene position: 2116496-2117281 (Clockwise)

Preceding gene: 218903337

Following gene: 218903339

Centisome position: 39.91

GC content: 38.42

Gene sequence:

>786_bases
ATGGAAAAGAAAGTAGTGGGTTATGTACGAGTTTCAACAGAAGGACAAGTACGTGACGGATACAGCTTAGCGTATCAAGT
AGAAGAAATCGAACGTTACTGTATGGAAAACAACTTACAATTGCTTCATGTATATGAAGATAGAGGACTAAGTGGCGCAA
CTGTTGATGAAAATGGATTAACAGTTGAACGTGAAGGCTTACAAGAACTATTGTCAGATATGGCATATCAACAAGTGAAG
CACGTGATTGTACTCAATACATCTCGGTTATCGCGCTCTGATATGGCAAAAGTGTTAATACAACGAGAGCTAAAGAAATA
CAAGGTAGATGTGAAAGCAATTGAACAACCGAATTACAGTATATATACACATGACCCCAATGACTTTTTAGTAAATGGCA
TGTTAGAGCTATTAGACCAATACCAACGTCTTGAAATTGCATTAAAACTAAGTAGAGGGAGAAAGAAGAAAGCGGAACAA
GGTGGATATGCGGGGGGCGGTGTGATGTTTGGTTACAGAGCAAATAAAGGACAAAAAGTGTTAGAAGTGGATACTAATAA
AGCAATCGTTGTACGTAGACTATTTGAGCTACGACACTTTTTTAAGCATTGGTCGCTAACTCAATTGGCAGAACGACTGA
ATAGGGAAGGCTATTGTACAGAGAAAGGGAAGCGGTTTACGAAAGTACAAGTGAAACGCATGTTAGACCGAGAGAACTTT
TATCGAGGGGTATATACATACGGGCAAATACAAACAAATGGGAAACATCCAGCAATTATTTTATAA

Upstream 100 bases:

>100_bases
TAAAGTACGTTTTAACGGATGGACGTTATGCACACGTTATCCGCAAAAAACGGGTAAACGTTACAGGAACTTTAATTGCT
GTAACGGGAGAGGACTCAAT

Downstream 100 bases:

>100_bases
ACTCACTTAAAAAATTAGCTCATTTTACTATACATACTACTAGAGTTATGAAAAATGGATAGGCTTGCGTACCTATGCGC
ATCGGAAGATGAACGCTCGA

Product: putative site-specific recombinase, resolvase family

Products: NA

Alternate protein names: Stage IV sporulation protein CA [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MEKKVVGYVRVSTEGQVRDGYSLAYQVEEIERYCMENNLQLLHVYEDRGLSGATVDENGLTVEREGLQELLSDMAYQQVK
HVIVLNTSRLSRSDMAKVLIQRELKKYKVDVKAIEQPNYSIYTHDPNDFLVNGMLELLDQYQRLEIALKLSRGRKKKAEQ
GGYAGGGVMFGYRANKGQKVLEVDTNKAIVVRRLFELRHFFKHWSLTQLAERLNREGYCTEKGKRFTKVQVKRMLDRENF
YRGVYTYGQIQTNGKHPAIIL

Sequences:

>Translated_261_residues
MEKKVVGYVRVSTEGQVRDGYSLAYQVEEIERYCMENNLQLLHVYEDRGLSGATVDENGLTVEREGLQELLSDMAYQQVK
HVIVLNTSRLSRSDMAKVLIQRELKKYKVDVKAIEQPNYSIYTHDPNDFLVNGMLELLDQYQRLEIALKLSRGRKKKAEQ
GGYAGGGVMFGYRANKGQKVLEVDTNKAIVVRRLFELRHFFKHWSLTQLAERLNREGYCTEKGKRFTKVQVKRMLDRENF
YRGVYTYGQIQTNGKHPAIIL
>Mature_261_residues
MEKKVVGYVRVSTEGQVRDGYSLAYQVEEIERYCMENNLQLLHVYEDRGLSGATVDENGLTVEREGLQELLSDMAYQQVK
HVIVLNTSRLSRSDMAKVLIQRELKKYKVDVKAIEQPNYSIYTHDPNDFLVNGMLELLDQYQRLEIALKLSRGRKKKAEQ
GGYAGGGVMFGYRANKGQKVLEVDTNKAIVVRRLFELRHFFKHWSLTQLAERLNREGYCTEKGKRFTKVQVKRMLDRENF
YRGVYTYGQIQTNGKHPAIIL

Specific function: Putative site-specific recombinase having a very important role in sporulation. It probably plays a role in the recombination of spoIIIC and spoIVCB to form sigma K factor [H]

COG id: COG1961

COG function: function code L; Site-specific recombinases, DNA invertase Pin homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 recombinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011109
- InterPro:   IPR006118
- InterPro:   IPR006119 [H]

Pfam domain/function: PF07508 Recombinase; PF00239 Resolvase [H]

EC number: NA

Molecular weight: Translated: 30295; Mature: 30295

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS00397 RECOMBINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKKVVGYVRVSTEGQVRDGYSLAYQVEEIERYCMENNLQLLHVYEDRGLSGATVDENGL
CCCCEEEEEEECCCCCCCCCHHHEEEHHHHHHHHHHCCCEEEEEEECCCCCCCEECCCCC
TVEREGLQELLSDMAYQQVKHVIVLNTSRLSRSDMAKVLIQRELKKYKVDVKAIEQPNYS
EEEHHHHHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCE
IYTHDPNDFLVNGMLELLDQYQRLEIALKLSRGRKKKAEQGGYAGGGVMFGYRANKGQKV
EEEECCCHHHHHHHHHHHHHHHHHHHHEEHHCCCCHHHHCCCCCCCCEEEEEECCCCCEE
LEVDTNKAIVVRRLFELRHFFKHWSLTQLAERLNREGYCTEKGKRFTKVQVKRMLDRENF
EEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
YRGVYTYGQIQTNGKHPAIIL
HHHEEEEEEEEECCCCCEEEC
>Mature Secondary Structure
MEKKVVGYVRVSTEGQVRDGYSLAYQVEEIERYCMENNLQLLHVYEDRGLSGATVDENGL
CCCCEEEEEEECCCCCCCCCHHHEEEHHHHHHHHHHCCCEEEEEEECCCCCCCEECCCCC
TVEREGLQELLSDMAYQQVKHVIVLNTSRLSRSDMAKVLIQRELKKYKVDVKAIEQPNYS
EEEHHHHHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCE
IYTHDPNDFLVNGMLELLDQYQRLEIALKLSRGRKKKAEQGGYAGGGVMFGYRANKGQKV
EEEECCCHHHHHHHHHHHHHHHHHHHHEEHHCCCCHHHHCCCCCCCCEEEEEECCCCCEE
LEVDTNKAIVVRRLFELRHFFKHWSLTQLAERLNREGYCTEKGKRFTKVQVKRMLDRENF
EEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
YRGVYTYGQIQTNGKHPAIIL
HHHEEEEEEEEECCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2105293; 7704261; 8969508; 9384377 [H]