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The map label for this gene is fabH [H]

Identifier: 218903083

GI number: 218903083

Start: 1873660

End: 1874655

Strand: Direct

Name: fabH [H]

Synonym: BCAH820_1966

Alternate gene names: 218903083

Gene position: 1873660-1874655 (Clockwise)

Preceding gene: 218903082

Following gene: 218903084

Centisome position: 35.33

GC content: 37.65

Gene sequence:

>996_bases
ATGAATATTGGGATTGAAGCGACTGGTGTTTTCTTCCCAAAAGACGTAGAGACGGCTGTAGATCTATCTAAGAAAACAGG
TATCCCTGAGAATATTATTATAGAAAAGTTTGGCTTATATGAAAAACATGTCGCAGACGAAATGATGCATGCATCAGATT
TAGCTATTGCTGCTGCAAAGCCAATATTATTACAAGTAAATCCTCAGTCTATTGATGTAGTCATTTATTTTGGCAGTCCA
CATAAAGATTACCACGTATGGTCTAGTGCCCCAAAAATTCAGCATGAACTTGGATTGAAAAATGCTTATGCTTTTGAAAT
TATGAATGTTAGTTCTTGCTTTCCAATCGCTCTCAAAGTCGCAAAAGACATGCTTTACTCCGATAACTCAATTGAAAATA
TATTATTGGTAGGTGGATGTAAAGAATCTCAAATTGTAGATTATGATAATCCACGCTCGCGTTTTATGTTTAATTTCGCT
GATGGCGGAAGTGCAGCTTTAGTGACAAAAGACGCTAAAAACGGTGAAATATTAGGAAGTGCGATAATAACAGATGGTTC
ATTTCATGAAGATGTTCGTATCCCAGCTGGTGGATCAAAGCAGGTTGCGAGCTATGATACAGTTGAGAATCGACAACATT
ATATTGATGTAATAGATCCTAATAGTATGAAAGAACGTCTAGACCCGATTTCAATCCCTAATTTTGACAAGGTTATTCGG
GAGGCGTTAAGAAAAAGTGGATATACTCCTAAAGATATTAAAGTATTGTTACCACTGCATACAAAACGTTCTATGTTAAT
AGAATTGATACAGGGGCTAGGGCTAACGGAAGAACAAGTCGTATATTTAGATCATTATGGGCATATGTCAGCGCTTGATC
CGTGTATTGGTCTTCACTTTGCAAATGAACAAGGAAAATTACAGGCCGGAGATATTGCAGTAGTAGTTAGTGCAGGGACT
GGGTATACATGGGCAGCGACTGTGATTAGGTGGTGA

Upstream 100 bases:

>100_bases
GAGTTTTGAAATTGTTAACGGAGTGTCATAACCAAAAAGGAGATTTAGTATTAACAGGTATAGCGACCATGATGGTGCCA
AAAAAAGGAGGAGTAGTCTA

Downstream 100 bases:

>100_bases
AAAATTCTAAATGAACATATGAGAAATGGAGGTATTTGGAAAGGAGCGGCGAATGTAATGGTACTTCATTAAATTTTCTC
AACAGATTTGTTTGTATGAT

Product: hypothetical protein

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MNIGIEATGVFFPKDVETAVDLSKKTGIPENIIIEKFGLYEKHVADEMMHASDLAIAAAKPILLQVNPQSIDVVIYFGSP
HKDYHVWSSAPKIQHELGLKNAYAFEIMNVSSCFPIALKVAKDMLYSDNSIENILLVGGCKESQIVDYDNPRSRFMFNFA
DGGSAALVTKDAKNGEILGSAIITDGSFHEDVRIPAGGSKQVASYDTVENRQHYIDVIDPNSMKERLDPISIPNFDKVIR
EALRKSGYTPKDIKVLLPLHTKRSMLIELIQGLGLTEEQVVYLDHYGHMSALDPCIGLHFANEQGKLQAGDIAVVVSAGT
GYTWAATVIRW

Sequences:

>Translated_331_residues
MNIGIEATGVFFPKDVETAVDLSKKTGIPENIIIEKFGLYEKHVADEMMHASDLAIAAAKPILLQVNPQSIDVVIYFGSP
HKDYHVWSSAPKIQHELGLKNAYAFEIMNVSSCFPIALKVAKDMLYSDNSIENILLVGGCKESQIVDYDNPRSRFMFNFA
DGGSAALVTKDAKNGEILGSAIITDGSFHEDVRIPAGGSKQVASYDTVENRQHYIDVIDPNSMKERLDPISIPNFDKVIR
EALRKSGYTPKDIKVLLPLHTKRSMLIELIQGLGLTEEQVVYLDHYGHMSALDPCIGLHFANEQGKLQAGDIAVVVSAGT
GYTWAATVIRW
>Mature_331_residues
MNIGIEATGVFFPKDVETAVDLSKKTGIPENIIIEKFGLYEKHVADEMMHASDLAIAAAKPILLQVNPQSIDVVIYFGSP
HKDYHVWSSAPKIQHELGLKNAYAFEIMNVSSCFPIALKVAKDMLYSDNSIENILLVGGCKESQIVDYDNPRSRFMFNFA
DGGSAALVTKDAKNGEILGSAIITDGSFHEDVRIPAGGSKQVASYDTVENRQHYIDVIDPNSMKERLDPISIPNFDKVIR
EALRKSGYTPKDIKVLLPLHTKRSMLIELIQGLGLTEEQVVYLDHYGHMSALDPCIGLHFANEQGKLQAGDIAVVVSAGT
GYTWAATVIRW

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=337, Percent_Identity=24.0356083086053, Blast_Score=85, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 36465; Mature: 36465

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIGIEATGVFFPKDVETAVDLSKKTGIPENIIIEKFGLYEKHVADEMMHASDLAIAAAK
CCCCEEEEEEECCCCHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHEEEECC
PILLQVNPQSIDVVIYFGSPHKDYHVWSSAPKIQHELGLKNAYAFEIMNVSSCFPIALKV
CEEEEECCCEEEEEEEECCCCCCEEEECCCCCHHHHHCCCCEEEEEEEECCCCHHHHHHH
AKDMLYSDNSIENILLVGGCKESQIVDYDNPRSRFMFNFADGGSAALVTKDAKNGEILGS
HHHHHCCCCCCCEEEEEECCCCCCEECCCCCCCEEEEEECCCCCEEEEEECCCCCCEEEE
AIITDGSFHEDVRIPAGGSKQVASYDTVENRQHYIDVIDPNSMKERLDPISIPNFDKVIR
EEEECCCCCCCEECCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHCCCCCCCCHHHHHH
EALRKSGYTPKDIKVLLPLHTKRSMLIELIQGLGLTEEQVVYLDHYGHMSALDPCIGLHF
HHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCHHEEEEEECCCCCHHCCHHHEEEE
ANEQGKLQAGDIAVVVSAGTGYTWAATVIRW
ECCCCCEEECCEEEEEECCCCCEEEEEEEEC
>Mature Secondary Structure
MNIGIEATGVFFPKDVETAVDLSKKTGIPENIIIEKFGLYEKHVADEMMHASDLAIAAAK
CCCCEEEEEEECCCCHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHEEEECC
PILLQVNPQSIDVVIYFGSPHKDYHVWSSAPKIQHELGLKNAYAFEIMNVSSCFPIALKV
CEEEEECCCEEEEEEEECCCCCCEEEECCCCCHHHHHCCCCEEEEEEEECCCCHHHHHHH
AKDMLYSDNSIENILLVGGCKESQIVDYDNPRSRFMFNFADGGSAALVTKDAKNGEILGS
HHHHHCCCCCCCEEEEEECCCCCCEECCCCCCCEEEEEECCCCCEEEEEECCCCCCEEEE
AIITDGSFHEDVRIPAGGSKQVASYDTVENRQHYIDVIDPNSMKERLDPISIPNFDKVIR
EEEECCCCCCCEECCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHCCCCCCCCHHHHHH
EALRKSGYTPKDIKVLLPLHTKRSMLIELIQGLGLTEEQVVYLDHYGHMSALDPCIGLHF
HHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCHHEEEEEECCCCCHHCCHHHEEEE
ANEQGKLQAGDIAVVVSAGTGYTWAATVIRW
ECCCCCEEECCEEEEEECCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]