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The map label for this gene is trpE [H]

Identifier: 218902434

GI number: 218902434

Start: 1254449

End: 1255867

Strand: Direct

Name: trpE [H]

Synonym: BCAH820_1316

Alternate gene names: 218902434

Gene position: 1254449-1255867 (Clockwise)

Preceding gene: 218902433

Following gene: 218902435

Centisome position: 23.66

GC content: 39.04

Gene sequence:

>1419_bases
ATGATGACAAAAGAGGAATTTATAAAACAGAAAGAACAAAGAAAAACATTTTTGGTAATCGCTGAAGAAGAAGGAGATAG
CATTACGCCAATTTCTTTATATAGACGTATGAAAGGTAAAAAGAAATTTTTATTAGAAAGCTCACAGCTTCATCAAGATA
AAGGGCGTTATTCTTACTTAGGTTGTAATCCATATGGTGAAGTGAAAAGCGTTGGTACGGAAGTGGAACGAACGATTTAC
GGCAGGGCAGAAAAGTTGCAAAGTAACGTACTACAAGTGTTAGAAGAAATAATCGCGTCCGCTCAAGTAGACAGTCCTTT
TCCATTTTGCGGAGGAGCAGTTGGTTATATTGGCTATGACGTCATTCGGCAATATGAAAACATTGGAGCAGATTTACACG
ACCCATTAAATATTCCAGAAGTACACCTTTTACTGTACCGTGAGTTTATCGTGTATGACCACTTATGCCAAAAGTTGTCG
TTTGTATATGTATGCAGGGAAGATGATTCAGCAGATTATGAAGAAGTATACGAAAGGCTGCGAGTATACAAACAGGAAGT
GCTACAGGGAGAAGAAGCGGAAGTAGCTGAAATAAGATCAACATTATCATTCACTTCTTATATAACGGAAAGAGAATTTT
GCGTGATGGTAGAAACGGCGAAAGAACACATCGGGGCCGGGGACATATTTCAAGTTGTATTATCTCAGCGTTTGCAAAGC
GAATGTATTGGAGATCCATTCGCGTTATATCGAAAACTTCGAATTGCCAATCCATCACCATATATGTTTTATATCGATTT
TCAAGATTATGTTGTACTCGGTTCTTCGCCAGAAAGTTTGTTATCAGTAAGGGAGGATAAAGTGATGACGAATCCAATTG
CTGGTACGAGGCCGAGAGGGAAAACGAAGGAGGAAGATACGGAGATTGAAAAAGAACTGTTAGAAAATGAGAAAGAGCGA
GCGGAGCATATGATGCTTGTAGATCTTGGGCGAAATGATATTGGTAGAGTGAGTGAAATCGGCTCAGTTACGATAGATAA
ATATATGAAAGTAGAAAAATATTCTCACGTTATGCACATTGTATCTGAAGTTTACGGAACATTGCGAAAACAAATGAGCG
GATTTGATGCATTAGCGTACTGTTTACCAGCGGGGACGGTATCAGGTGCTCCGAAAATTAGAGCGATGGAAATTATAAAT
GAGCTAGAGAATGAAAAAAGAAATGTGTACGCCGGTGCAGTTGGATACGTTAGTTTTTCAGGGAATCTTGATATGGCGCT
CGCCATTCGAACAATGGTTGTAAAGGATGAAAAAGCATACATTCAGGCAGGAGCGGGTATTGTTTACGATTCAGATCCAG
TAGCTGAATATGAAGAAACATTAAATAAAGCGAGAGCGCTATTGGAGGTAATGAAATGA

Upstream 100 bases:

>100_bases
TTTGCGTCCAACATGAGGTGGTACCACGGTAAATTTATCGTCCTCTACATATTTTCGATATGTAGAGGACTTTTTTATTT
TTCAGGATGAGGTGAAAGGC

Downstream 100 bases:

>100_bases
TTGTACTGATCGATAATTATGATTCATTCACATATAACTTGTATCAACTATTAGGCGAATACGAAGAAGAAATTGTTGTC
GTAAGAAATGATCAAATAAC

Product: anthranilate synthase component I

Products: NA

Alternate protein names: Anthranilate synthase component I [H]

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MMTKEEFIKQKEQRKTFLVIAEEEGDSITPISLYRRMKGKKKFLLESSQLHQDKGRYSYLGCNPYGEVKSVGTEVERTIY
GRAEKLQSNVLQVLEEIIASAQVDSPFPFCGGAVGYIGYDVIRQYENIGADLHDPLNIPEVHLLLYREFIVYDHLCQKLS
FVYVCREDDSADYEEVYERLRVYKQEVLQGEEAEVAEIRSTLSFTSYITEREFCVMVETAKEHIGAGDIFQVVLSQRLQS
ECIGDPFALYRKLRIANPSPYMFYIDFQDYVVLGSSPESLLSVREDKVMTNPIAGTRPRGKTKEEDTEIEKELLENEKER
AEHMMLVDLGRNDIGRVSEIGSVTIDKYMKVEKYSHVMHIVSEVYGTLRKQMSGFDALAYCLPAGTVSGAPKIRAMEIIN
ELENEKRNVYAGAVGYVSFSGNLDMALAIRTMVVKDEKAYIQAGAGIVYDSDPVAEYEETLNKARALLEVMK

Sequences:

>Translated_472_residues
MMTKEEFIKQKEQRKTFLVIAEEEGDSITPISLYRRMKGKKKFLLESSQLHQDKGRYSYLGCNPYGEVKSVGTEVERTIY
GRAEKLQSNVLQVLEEIIASAQVDSPFPFCGGAVGYIGYDVIRQYENIGADLHDPLNIPEVHLLLYREFIVYDHLCQKLS
FVYVCREDDSADYEEVYERLRVYKQEVLQGEEAEVAEIRSTLSFTSYITEREFCVMVETAKEHIGAGDIFQVVLSQRLQS
ECIGDPFALYRKLRIANPSPYMFYIDFQDYVVLGSSPESLLSVREDKVMTNPIAGTRPRGKTKEEDTEIEKELLENEKER
AEHMMLVDLGRNDIGRVSEIGSVTIDKYMKVEKYSHVMHIVSEVYGTLRKQMSGFDALAYCLPAGTVSGAPKIRAMEIIN
ELENEKRNVYAGAVGYVSFSGNLDMALAIRTMVVKDEKAYIQAGAGIVYDSDPVAEYEETLNKARALLEVMK
>Mature_472_residues
MMTKEEFIKQKEQRKTFLVIAEEEGDSITPISLYRRMKGKKKFLLESSQLHQDKGRYSYLGCNPYGEVKSVGTEVERTIY
GRAEKLQSNVLQVLEEIIASAQVDSPFPFCGGAVGYIGYDVIRQYENIGADLHDPLNIPEVHLLLYREFIVYDHLCQKLS
FVYVCREDDSADYEEVYERLRVYKQEVLQGEEAEVAEIRSTLSFTSYITEREFCVMVETAKEHIGAGDIFQVVLSQRLQS
ECIGDPFALYRKLRIANPSPYMFYIDFQDYVVLGSSPESLLSVREDKVMTNPIAGTRPRGKTKEEDTEIEKELLENEKER
AEHMMLVDLGRNDIGRVSEIGSVTIDKYMKVEKYSHVMHIVSEVYGTLRKQMSGFDALAYCLPAGTVSGAPKIRAMEIIN
ELENEKRNVYAGAVGYVSFSGNLDMALAIRTMVVKDEKAYIQAGAGIVYDSDPVAEYEETLNKARALLEVMK

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=436, Percent_Identity=30.9633027522936, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI1787518, Length=365, Percent_Identity=36.7123287671233, Blast_Score=235, Evalue=5e-63,
Organism=Escherichia coli, GI1786809, Length=292, Percent_Identity=27.3972602739726, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI87082077, Length=313, Percent_Identity=26.1980830670927, Blast_Score=89, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6320935, Length=442, Percent_Identity=41.1764705882353, Blast_Score=325, Evalue=7e-90,
Organism=Saccharomyces cerevisiae, GI6324361, Length=407, Percent_Identity=25.5528255528256, Blast_Score=122, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR005256
- InterPro:   IPR015890 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 53687; Mature: 53687

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTKEEFIKQKEQRKTFLVIAEEEGDSITPISLYRRMKGKKKFLLESSQLHQDKGRYSYL
CCCHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEE
GCNPYGEVKSVGTEVERTIYGRAEKLQSNVLQVLEEIIASAQVDSPFPFCGGAVGYIGYD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
VIRQYENIGADLHDPLNIPEVHLLLYREFIVYDHLCQKLSFVYVCREDDSADYEEVYERL
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHH
RVYKQEVLQGEEAEVAEIRSTLSFTSYITEREFCVMVETAKEHIGAGDIFQVVLSQRLQS
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHCCCHHHHHHHHHHHHHH
ECIGDPFALYRKLRIANPSPYMFYIDFQDYVVLGSSPESLLSVREDKVMTNPIAGTRPRG
HHCCCHHHHHHHHHCCCCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCC
KTKEEDTEIEKELLENEKERAEHMMLVDLGRNDIGRVSEIGSVTIDKYMKVEKYSHVMHI
CCCCHHHHHHHHHHHCHHHHHHHEEEEECCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHH
VSEVYGTLRKQMSGFDALAYCLPAGTVSGAPKIRAMEIINELENEKRNVYAGAVGYVSFS
HHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEEEEEEEC
GNLDMALAIRTMVVKDEKAYIQAGAGIVYDSDPVAEYEETLNKARALLEVMK
CCCCHHHHHHHHHHCCCHHHHEECCCEEECCCCHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MMTKEEFIKQKEQRKTFLVIAEEEGDSITPISLYRRMKGKKKFLLESSQLHQDKGRYSYL
CCCHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEE
GCNPYGEVKSVGTEVERTIYGRAEKLQSNVLQVLEEIIASAQVDSPFPFCGGAVGYIGYD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
VIRQYENIGADLHDPLNIPEVHLLLYREFIVYDHLCQKLSFVYVCREDDSADYEEVYERL
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHH
RVYKQEVLQGEEAEVAEIRSTLSFTSYITEREFCVMVETAKEHIGAGDIFQVVLSQRLQS
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHCCCHHHHHHHHHHHHHH
ECIGDPFALYRKLRIANPSPYMFYIDFQDYVVLGSSPESLLSVREDKVMTNPIAGTRPRG
HHCCCHHHHHHHHHCCCCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCC
KTKEEDTEIEKELLENEKERAEHMMLVDLGRNDIGRVSEIGSVTIDKYMKVEKYSHVMHI
CCCCHHHHHHHHHHHCHHHHHHHEEEEECCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHH
VSEVYGTLRKQMSGFDALAYCLPAGTVSGAPKIRAMEIINELENEKRNVYAGAVGYVSFS
HHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEEEEEEEC
GNLDMALAIRTMVVKDEKAYIQAGAGIVYDSDPVAEYEETLNKARALLEVMK
CCCCHHHHHHHHHHCCCHHHHEECCCEEECCCCHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2732211 [H]