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The map label for this gene is dppE [H]

Identifier: 218902385

GI number: 218902385

Start: 1212645

End: 1214291

Strand: Direct

Name: dppE [H]

Synonym: BCAH820_1267

Alternate gene names: 218902385

Gene position: 1212645-1214291 (Clockwise)

Preceding gene: 218902383

Following gene: 218902387

Centisome position: 22.87

GC content: 34.67

Gene sequence:

>1647_bases
ATGAAAAAAAAGATTCCAGTTTTTGTAGTATCAACAGTAGCAATGAGCATGATGTTAGGGGCATGTAGCTACCAAAAAGA
TGAGCCGCAAGCGAACGCAAAAGGGGATAGCGGGAAAAGCGGTGCGAAGCAAGTTATTAATCTAACGGAAGTGTCTGAAA
TTCCGACGATGGATACGACACTTGCCTCGGATGCTGCTTCTTCAAAAGTTATGAATAATACAATGGAAGGGCTATATCGA
CTTGGGAAAGGCGATAAGTTAGTTCCAGGTGTAGCGAAATCTCATACGAAATCTGAAGATGGTAAAAAATATACATTTAA
ATTGCGTGAAGACGCTAAATGGTCGAATGGTGATCCTGTAACAGCAAAAGATTTTGTATATGCATGGCAAAGAGCTGTTA
ACCCTGATACGGCAGCGAAATCAGGATATATTATGCTTGATGTGAAAAATGCAGAGAAAATTAATAAAAGGGAGCTATCA
CCGGATCAATTAGGTGTAAAAGCGATAGATGATTATACATTTGAAGTTGAATTGGATAATCCAGTTCCATATTTTCTTGA
TTTAACGGTGTACCCACTATTTTTCCCATTAAATGAGAAGTATATGAAAGAACAGGGAGAAAAATTTGGTTTAGAAGCAA
ATACAACTTTGTATAACGGTCCATTTGTATTAAATGAATGGAAACATGAACAAAGTTTCCAATTAAAGAAAAACCCAAGC
TATTGGGATCAAAAAGAAGTAAAATTAGAAGAAGTTAATTTTAATGTTGTAAAAGATACAGGAGCAGCTGTTAATTTGTA
TAATACGAGTGCGATTGACAGAGTCGGTTTATCAGCTGAGTTAGTTGATAAGTATAAAGGACAACAAGACTTTAAAACAA
TTAATGATCCAACTGTATTCTTCTTACGTTTTAATCAAAAAAATCCAGCTTTAGCTAACAAAAATATTCGTAAGGCTATT
TCTAGTGCATACGATCGAGATGGTATTGGTGAGGTTATTTTAAACAACGGTTCTAAGGGAGCTTACGGTTTAGTACCATC
TGATTTTGTTAAGGGACCAGATAAGCAAGATTTCAGAAAAGAAAATGGGAAACTTTCAAAAGTTGATGTGAAGGAAGCTA
AAAAATTCTGGGAAGCTGGAAAGAAAGAATTAGGTAAAGATAAAATAGAACTAGAATTTTTAAACTTTGATAATGAAGAA
TCTAAGAAAATTGGTGAGTATGTAAAGGGAGAATTAGAAAAGAATTTACCAGGTCTAACAGTAACAATTAAGATGCAACC
ATTTGCCCAAAAATTAAAACTTGAAGATAGTGGACAGTTTGATATTTCATTTACTGGATGGGGACCTGATTTCCCTGATG
CAATCACATTCCTTGATATGTTTATAACAGATGGTTCACAAAATAAAATGGGTTATTCTAATGCTGAGTATGATAGCCTT
ATTAAAAAGGCAAAGCAAGAAGGTTCAGATGTAAAAGGACGTTGGAATGACCTGTTAAAAGCGGAAAAAATCTTATTTGA
GGATGCAGCAATTGCACCAGTATTCCAACGCGGCAGATCTATATTAGAAAGAGAAACAATTAAAGATGTATATATCCACA
AATATGGCGGCGAATTAAGCTTTAAGTGGGCATCTGTAGAAAAATAA

Upstream 100 bases:

>100_bases
AAAAAATATATTTGTGTGTATAATATGAATTGTTAGAACATATATATATTTCTTTTTGTTTGAAAATGAAAGGGCTAACA
TTTTTGTGGAGGGTGGAAGT

Downstream 100 bases:

>100_bases
AAAAGCAGGCTAACCGCCTGCTTTTTTTAATACGTACGTTTCTTATAAATACCTTTCCCGCCGACCTCGTTCCAGCCGGA
TTGCACATCCAAACTTTTAT

Product: oligopeptide ABC transporter, oligopeptide-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 548; Mature: 548

Protein sequence:

>548_residues
MKKKIPVFVVSTVAMSMMLGACSYQKDEPQANAKGDSGKSGAKQVINLTEVSEIPTMDTTLASDAASSKVMNNTMEGLYR
LGKGDKLVPGVAKSHTKSEDGKKYTFKLREDAKWSNGDPVTAKDFVYAWQRAVNPDTAAKSGYIMLDVKNAEKINKRELS
PDQLGVKAIDDYTFEVELDNPVPYFLDLTVYPLFFPLNEKYMKEQGEKFGLEANTTLYNGPFVLNEWKHEQSFQLKKNPS
YWDQKEVKLEEVNFNVVKDTGAAVNLYNTSAIDRVGLSAELVDKYKGQQDFKTINDPTVFFLRFNQKNPALANKNIRKAI
SSAYDRDGIGEVILNNGSKGAYGLVPSDFVKGPDKQDFRKENGKLSKVDVKEAKKFWEAGKKELGKDKIELEFLNFDNEE
SKKIGEYVKGELEKNLPGLTVTIKMQPFAQKLKLEDSGQFDISFTGWGPDFPDAITFLDMFITDGSQNKMGYSNAEYDSL
IKKAKQEGSDVKGRWNDLLKAEKILFEDAAIAPVFQRGRSILERETIKDVYIHKYGGELSFKWASVEK

Sequences:

>Translated_548_residues
MKKKIPVFVVSTVAMSMMLGACSYQKDEPQANAKGDSGKSGAKQVINLTEVSEIPTMDTTLASDAASSKVMNNTMEGLYR
LGKGDKLVPGVAKSHTKSEDGKKYTFKLREDAKWSNGDPVTAKDFVYAWQRAVNPDTAAKSGYIMLDVKNAEKINKRELS
PDQLGVKAIDDYTFEVELDNPVPYFLDLTVYPLFFPLNEKYMKEQGEKFGLEANTTLYNGPFVLNEWKHEQSFQLKKNPS
YWDQKEVKLEEVNFNVVKDTGAAVNLYNTSAIDRVGLSAELVDKYKGQQDFKTINDPTVFFLRFNQKNPALANKNIRKAI
SSAYDRDGIGEVILNNGSKGAYGLVPSDFVKGPDKQDFRKENGKLSKVDVKEAKKFWEAGKKELGKDKIELEFLNFDNEE
SKKIGEYVKGELEKNLPGLTVTIKMQPFAQKLKLEDSGQFDISFTGWGPDFPDAITFLDMFITDGSQNKMGYSNAEYDSL
IKKAKQEGSDVKGRWNDLLKAEKILFEDAAIAPVFQRGRSILERETIKDVYIHKYGGELSFKWASVEK
>Mature_548_residues
MKKKIPVFVVSTVAMSMMLGACSYQKDEPQANAKGDSGKSGAKQVINLTEVSEIPTMDTTLASDAASSKVMNNTMEGLYR
LGKGDKLVPGVAKSHTKSEDGKKYTFKLREDAKWSNGDPVTAKDFVYAWQRAVNPDTAAKSGYIMLDVKNAEKINKRELS
PDQLGVKAIDDYTFEVELDNPVPYFLDLTVYPLFFPLNEKYMKEQGEKFGLEANTTLYNGPFVLNEWKHEQSFQLKKNPS
YWDQKEVKLEEVNFNVVKDTGAAVNLYNTSAIDRVGLSAELVDKYKGQQDFKTINDPTVFFLRFNQKNPALANKNIRKAI
SSAYDRDGIGEVILNNGSKGAYGLVPSDFVKGPDKQDFRKENGKLSKVDVKEAKKFWEAGKKELGKDKIELEFLNFDNEE
SKKIGEYVKGELEKNLPGLTVTIKMQPFAQKLKLEDSGQFDISFTGWGPDFPDAITFLDMFITDGSQNKMGYSNAEYDSL
IKKAKQEGSDVKGRWNDLLKAEKILFEDAAIAPVFQRGRSILERETIKDVYIHKYGGELSFKWASVEK

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI87081878, Length=532, Percent_Identity=29.8872180451128, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI1787495, Length=517, Percent_Identity=29.2069632495164, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI1789397, Length=505, Percent_Identity=27.5247524752475, Blast_Score=188, Evalue=7e-49,
Organism=Escherichia coli, GI1787762, Length=458, Percent_Identity=24.6724890829694, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI1787052, Length=322, Percent_Identity=24.8447204968944, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789966, Length=506, Percent_Identity=23.7154150197628, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1789887, Length=358, Percent_Identity=24.0223463687151, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 61642; Mature: 61642

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKIPVFVVSTVAMSMMLGACSYQKDEPQANAKGDSGKSGAKQVINLTEVSEIPTMDTT
CCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHH
LASDAASSKVMNNTMEGLYRLGKGDKLVPGVAKSHTKSEDGKKYTFKLREDAKWSNGDPV
HHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHCCCCCCCCCEEEEEEECCCCCCCCCCC
TAKDFVYAWQRAVNPDTAAKSGYIMLDVKNAEKINKRELSPDQLGVKAIDDYTFEVELDN
CHHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHCCCHHHCCCEEECCEEEEEEECC
PVPYFLDLTVYPLFFPLNEKYMKEQGEKFGLEANTTLYNGPFVLNEWKHEQSFQLKKNPS
CCCEEEEEEEEEEEECCCHHHHHHCCHHCCCCCCCEEECCCEEEECCCCCCCEEECCCCC
YWDQKEVKLEEVNFNVVKDTGAAVNLYNTSAIDRVGLSAELVDKYKGQQDFKTINDPTVF
CCCCCCCEEEECCEEEEECCCCEEEEECCCHHHHCCCCHHHHHHHCCCHHHCCCCCCEEE
FLRFNQKNPALANKNIRKAISSAYDRDGIGEVILNNGSKGAYGLVPSDFVKGPDKQDFRK
EEEECCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHCCCCHHHHHH
ENGKLSKVDVKEAKKFWEAGKKELGKDKIELEFLNFDNEESKKIGEYVKGELEKNLPGLT
HCCCEEEECHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEE
VTIKMQPFAQKLKLEDSGQFDISFTGWGPDFPDAITFLDMFITDGSQNKMGYSNAEYDSL
EEEEECHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
IKKAKQEGSDVKGRWNDLLKAEKILFEDAAIAPVFQRGRSILERETIKDVYIHKYGGELS
HHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCEE
FKWASVEK
EEECCCCC
>Mature Secondary Structure
MKKKIPVFVVSTVAMSMMLGACSYQKDEPQANAKGDSGKSGAKQVINLTEVSEIPTMDTT
CCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHH
LASDAASSKVMNNTMEGLYRLGKGDKLVPGVAKSHTKSEDGKKYTFKLREDAKWSNGDPV
HHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHCCCCCCCCCEEEEEEECCCCCCCCCCC
TAKDFVYAWQRAVNPDTAAKSGYIMLDVKNAEKINKRELSPDQLGVKAIDDYTFEVELDN
CHHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHCCCHHHCCCEEECCEEEEEEECC
PVPYFLDLTVYPLFFPLNEKYMKEQGEKFGLEANTTLYNGPFVLNEWKHEQSFQLKKNPS
CCCEEEEEEEEEEEECCCHHHHHHCCHHCCCCCCCEEECCCEEEECCCCCCCEEECCCCC
YWDQKEVKLEEVNFNVVKDTGAAVNLYNTSAIDRVGLSAELVDKYKGQQDFKTINDPTVF
CCCCCCCEEEECCEEEEECCCCEEEEECCCHHHHCCCCHHHHHHHCCCHHHCCCCCCEEE
FLRFNQKNPALANKNIRKAISSAYDRDGIGEVILNNGSKGAYGLVPSDFVKGPDKQDFRK
EEEECCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHCCCCHHHHHH
ENGKLSKVDVKEAKKFWEAGKKELGKDKIELEFLNFDNEESKKIGEYVKGELEKNLPGLT
HCCCEEEECHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEE
VTIKMQPFAQKLKLEDSGQFDISFTGWGPDFPDAITFLDMFITDGSQNKMGYSNAEYDSL
EEEEECHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
IKKAKQEGSDVKGRWNDLLKAEKILFEDAAIAPVFQRGRSILERETIKDVYIHKYGGELS
HHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCEE
FKWASVEK
EEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]