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The map label for this gene is rocD [H]

Identifier: 218902349

GI number: 218902349

Start: 1175042

End: 1176232

Strand: Reverse

Name: rocD [H]

Synonym: BCAH820_1231

Alternate gene names: 218902349

Gene position: 1176232-1175042 (Counterclockwise)

Preceding gene: 218902351

Following gene: 218902348

Centisome position: 22.18

GC content: 40.89

Gene sequence:

>1191_bases
ATGATTCAAACTAAGGATATCATCGAACTTACAGACACATACGGGGCAAATAACTATCACCCACTTCCAATCGTTATTTC
TAAAGCAGAAGGCGTTTGGGTAGAAGATCCTGAAGGAAACCGCTATATGGACTTATTAAGTGCATATTCGGCAGTAAACC
AAGGTCATCGTCACCCAAAAATTATTAACGCTTTAATTGACCAAGCTAATCGTGTTACGTTAACTTCTCGTGCTTTCCAT
AGCGATCAATTAGGTCCTTGGTACGAAAAAGTTGCGAAACTAACTAATAAAGAAATGGTACTTCCAATGAATACAGGTGC
AGAAGCTGTTGAAACTGCAATTAAAACAGCTCGCCGCTGGGCTTATGATGTGAAGAAAGTAGAAGCAAATCGTGCTGAGA
TTATCGTTTGTGAAGATAACTTCCACGGACGTACGATGGGTGCTGTTTCTATGTCTTCAAACGAAGAGTACAAGCGTGGA
TTCGGTCCAATGCTTCCTGGCATTATCGTAATTCCTTACGGTGATTTAGAAGCGTTAAAAGCTGCTATTACACCAAACAC
AGCTGCATTCATTTTAGAGCCAATCCAAGGTGAAGCAGGAATTAACATCCCACCAGCTGGTTTCTTAAAAGAAGCTCTTG
AAGTATGTAAAAAAGAAAACGTTTTATTCGTAGCAGATGAAATCCAAACTGGCTTAGGCCGTACTGGTAAAGTATTTGCT
TGTGACTGGGACGGTGTAACTCCTGACATGTACATACTTGGTAAAGCACTTGGCGGCGGCGTATTCCCAATCTCTTGCGT
AGCAGCAAACCGCGACATTTTAGGCGTATTCGAGCCAGGTTCTCACGGTTCTACATTCGGTGGTAACCCACTTGCATGTG
CTGTTTCTATCGCAGCTCTTGAAGTGTTAGAAGAAGAAAAATTAACAGAGCGTTCTCTTCAATTAGGTGAAAAATTAGTT
GGGCAATTAAAAGAGATTGATAACCCAATGATCACTGAAGTTCGCGGTAAAGGTTTATTCATCGGTATCGAATTAAACGA
GCCAGCTCGTCCTTACTGTGAACAACTAAAAGCAGCTGGTCTATTATGTAAAGAAACACACGAAAATGTAATTCGTATCG
CACCACCACTAGTAATCTCTGAAGAAGATTTAGAGTGGGCGTTCCAAAAAATTAAAGCGGTATTATCGTAA

Upstream 100 bases:

>100_bases
GTTCATTTATTTTCAGGAAATGTTTCGCTTTTTTACATTTAAATGATATAATATTTAGAGTATTTACAAACTTCTTGTAA
TAACAAAAGGGGGAACAATC

Downstream 100 bases:

>100_bases
TAATAGAGAGTCTGTCCTACACGTTAGGACAGACTCTTTCTTTTTTTAGTAGTTTATCGTAAAATAAATTTTAATATTCT
GTCTTTTTTACGAAAGGGGT

Product: ornithine--oxo-acid transaminase

Products: NA

Alternate protein names: OAT; Ornithine--oxo-acid aminotransferase [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MIQTKDIIELTDTYGANNYHPLPIVISKAEGVWVEDPEGNRYMDLLSAYSAVNQGHRHPKIINALIDQANRVTLTSRAFH
SDQLGPWYEKVAKLTNKEMVLPMNTGAEAVETAIKTARRWAYDVKKVEANRAEIIVCEDNFHGRTMGAVSMSSNEEYKRG
FGPMLPGIIVIPYGDLEALKAAITPNTAAFILEPIQGEAGINIPPAGFLKEALEVCKKENVLFVADEIQTGLGRTGKVFA
CDWDGVTPDMYILGKALGGGVFPISCVAANRDILGVFEPGSHGSTFGGNPLACAVSIAALEVLEEEKLTERSLQLGEKLV
GQLKEIDNPMITEVRGKGLFIGIELNEPARPYCEQLKAAGLLCKETHENVIRIAPPLVISEEDLEWAFQKIKAVLS

Sequences:

>Translated_396_residues
MIQTKDIIELTDTYGANNYHPLPIVISKAEGVWVEDPEGNRYMDLLSAYSAVNQGHRHPKIINALIDQANRVTLTSRAFH
SDQLGPWYEKVAKLTNKEMVLPMNTGAEAVETAIKTARRWAYDVKKVEANRAEIIVCEDNFHGRTMGAVSMSSNEEYKRG
FGPMLPGIIVIPYGDLEALKAAITPNTAAFILEPIQGEAGINIPPAGFLKEALEVCKKENVLFVADEIQTGLGRTGKVFA
CDWDGVTPDMYILGKALGGGVFPISCVAANRDILGVFEPGSHGSTFGGNPLACAVSIAALEVLEEEKLTERSLQLGEKLV
GQLKEIDNPMITEVRGKGLFIGIELNEPARPYCEQLKAAGLLCKETHENVIRIAPPLVISEEDLEWAFQKIKAVLS
>Mature_396_residues
MIQTKDIIELTDTYGANNYHPLPIVISKAEGVWVEDPEGNRYMDLLSAYSAVNQGHRHPKIINALIDQANRVTLTSRAFH
SDQLGPWYEKVAKLTNKEMVLPMNTGAEAVETAIKTARRWAYDVKKVEANRAEIIVCEDNFHGRTMGAVSMSSNEEYKRG
FGPMLPGIIVIPYGDLEALKAAITPNTAAFILEPIQGEAGINIPPAGFLKEALEVCKKENVLFVADEIQTGLGRTGKVFA
CDWDGVTPDMYILGKALGGGVFPISCVAANRDILGVFEPGSHGSTFGGNPLACAVSIAALEVLEEEKLTERSLQLGEKLV
GQLKEIDNPMITEVRGKGLFIGIELNEPARPYCEQLKAAGLLCKETHENVIRIAPPLVISEEDLEWAFQKIKAVLS

Specific function: Catalyzes the interconversion of ornithine to glutamate semialdehyde [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=399, Percent_Identity=50.6265664160401, Blast_Score=404, Evalue=1e-113,
Organism=Homo sapiens, GI284507298, Length=300, Percent_Identity=50, Blast_Score=290, Evalue=2e-78,
Organism=Homo sapiens, GI13994255, Length=435, Percent_Identity=29.1954022988506, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI24119277, Length=417, Percent_Identity=28.7769784172662, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI37574042, Length=419, Percent_Identity=27.6849642004773, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI226442705, Length=419, Percent_Identity=26.9689737470167, Blast_Score=142, Evalue=8e-34,
Organism=Homo sapiens, GI226442709, Length=387, Percent_Identity=27.6485788113695, Blast_Score=140, Evalue=2e-33,
Organism=Escherichia coli, GI1789759, Length=379, Percent_Identity=36.9393139841689, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI145693181, Length=378, Percent_Identity=34.1269841269841, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI1788044, Length=381, Percent_Identity=34.3832020997375, Blast_Score=222, Evalue=3e-59,
Organism=Escherichia coli, GI1787560, Length=407, Percent_Identity=32.1867321867322, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1789016, Length=406, Percent_Identity=30.5418719211823, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1786991, Length=362, Percent_Identity=31.767955801105, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1786349, Length=356, Percent_Identity=28.9325842696629, Blast_Score=117, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI25144271, Length=389, Percent_Identity=49.8714652956298, Blast_Score=400, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI25144274, Length=266, Percent_Identity=48.1203007518797, Blast_Score=258, Evalue=3e-69,
Organism=Caenorhabditis elegans, GI32564660, Length=431, Percent_Identity=32.7146171693735, Blast_Score=194, Evalue=6e-50,
Organism=Caenorhabditis elegans, GI71981843, Length=176, Percent_Identity=48.2954545454545, Blast_Score=187, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI71992977, Length=430, Percent_Identity=28.1395348837209, Blast_Score=155, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17541228, Length=426, Percent_Identity=24.1784037558685, Blast_Score=96, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6323470, Length=412, Percent_Identity=50.7281553398058, Blast_Score=395, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6324432, Length=382, Percent_Identity=31.9371727748691, Blast_Score=187, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6324386, Length=468, Percent_Identity=25.4273504273504, Blast_Score=104, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6321456, Length=405, Percent_Identity=23.7037037037037, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357415, Length=389, Percent_Identity=52.1850899742931, Blast_Score=405, Evalue=1e-113,
Organism=Drosophila melanogaster, GI161085790, Length=427, Percent_Identity=29.7423887587822, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI28574759, Length=422, Percent_Identity=30.0947867298578, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI21356575, Length=418, Percent_Identity=26.7942583732057, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI281366494, Length=427, Percent_Identity=24.824355971897, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24667139, Length=427, Percent_Identity=24.824355971897, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24667143, Length=427, Percent_Identity=24.824355971897, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR010164
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.13 [H]

Molecular weight: Translated: 43243; Mature: 43243

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQTKDIIELTDTYGANNYHPLPIVISKAEGVWVEDPEGNRYMDLLSAYSAVNQGHRHPK
CCCCCCHHHHHHCCCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHH
IINALIDQANRVTLTSRAFHSDQLGPWYEKVAKLTNKEMVLPMNTGAEAVETAIKTARRW
HHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHH
AYDVKKVEANRAEIIVCEDNFHGRTMGAVSMSSNEEYKRGFGPMLPGIIVIPYGDLEALK
HHHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCCHHHHCCCCCCCCEEEEECCCHHHHH
AAITPNTAAFILEPIQGEAGINIPPAGFLKEALEVCKKENVLFVADEIQTGLGRTGKVFA
HHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEHHHHHCCCCCCCEEE
CDWDGVTPDMYILGKALGGGVFPISCVAANRDILGVFEPGSHGSTFGGNPLACAVSIAAL
EECCCCCCCHHHHHHHHCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHH
EVLEEEKLTERSLQLGEKLVGQLKEIDNPMITEVRGKGLFIGIELNEPARPYCEQLKAAG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEEEEECCCCCHHHHHHHHCC
LLCKETHENVIRIAPPLVISEEDLEWAFQKIKAVLS
CHHHHHHCCEEEECCCEEECCCHHHHHHHHHHHHHC
>Mature Secondary Structure
MIQTKDIIELTDTYGANNYHPLPIVISKAEGVWVEDPEGNRYMDLLSAYSAVNQGHRHPK
CCCCCCHHHHHHCCCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHH
IINALIDQANRVTLTSRAFHSDQLGPWYEKVAKLTNKEMVLPMNTGAEAVETAIKTARRW
HHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHH
AYDVKKVEANRAEIIVCEDNFHGRTMGAVSMSSNEEYKRGFGPMLPGIIVIPYGDLEALK
HHHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCCHHHHCCCCCCCCEEEEECCCHHHHH
AAITPNTAAFILEPIQGEAGINIPPAGFLKEALEVCKKENVLFVADEIQTGLGRTGKVFA
HHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEHHHHHCCCCCCCEEE
CDWDGVTPDMYILGKALGGGVFPISCVAANRDILGVFEPGSHGSTFGGNPLACAVSIAAL
EECCCCCCCHHHHHHHHCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHH
EVLEEEKLTERSLQLGEKLVGQLKEIDNPMITEVRGKGLFIGIELNEPARPYCEQLKAAG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEEEEECCCCCHHHHHHHHCC
LLCKETHENVIRIAPPLVISEEDLEWAFQKIKAVLS
CHHHHHHCCEEEECCCEEECCCHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA