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The map label for this gene is yhfN [H]

Identifier: 218902321

GI number: 218902321

Start: 1150879

End: 1152144

Strand: Direct

Name: yhfN [H]

Synonym: BCAH820_1203

Alternate gene names: 218902321

Gene position: 1150879-1152144 (Clockwise)

Preceding gene: 218902320

Following gene: 218902322

Centisome position: 21.7

GC content: 36.81

Gene sequence:

>1266_bases
GTGAGGAAGGTTATCGGGTGGTCGCTTTTTTTGTACGTTGGGTTTGCATTATTTATATATTGGTATTTATTTGGATGGAA
TCATGAACTAATTCCTGACATGTACAAAGGAACGAGTGCAGATCCAGAAACGTTTATGAATGCAAGAGAGCTTACGCTAA
GCCAAGATTATTCGCGCGTGAAAAATTTACTGTATTTTTTAGCGACGCCTCTTGAATGGATTATTTTATTATTTGTACTT
GTGCTCGGTATTTCAAAAAAGTTTGAGAAATGGTCGAAGGAAACGACGAAAATAAGTGTTCTGCAAGTTGCGATTTATTT
CTTTTATTTATCACTACTCACAACAGTTCTTGCCTTGCCGATGCAATGGATTAGCCGAAAAGTGTCCGTTGATTACGGCA
TTTCAACGCAAAGTACACAAAGCTGGATAAAAGATCACGTTATCGGTTTTTGGGAAAGTTATGCGACGATGTTAATTGTA
GTTGCCGTTCTGTTATGGCTTATCCGTAAATTCCCGAAGAGATGGTGGCTAGCAGGGTGGGCGCTCTCTGTACCATTTAC
AATCTTTTTAACATTTATACAGCCTGTCGTTATTGATCCACTTTATAACGACTTTTCGACGCTGAAAAATAAGGAATTAG
AAACGAAAATTTTAGCGATAGCGGACAAAGCGGACATTCCTGCTAAACACGTGTATGAAGTAAATATGTCAGAGAAAACG
AATGCGTTAAATGCATATGTAACAGGAATTGGCCCTAACGCTCGTATTGTAATGTGGGATACAACGCTTAAGCAATTAAA
AGATAAAGAGATTTTATTTATAATGGCCCATGAAATGGGGCATTATGTTATGAAACATATATATTGGGGCGTTGCGAGTT
ATATGTTGCTATCGTTTATAGGGATGTATCTTATTAGTCGTATTATCAATATGTGTATTCGAAAATGGGGGAATACGCTG
CAAATTTCAAAAGCAGCATGTTTCTCAATTTTACCTTTATTTTTCTTAATTTCTTCTGTACTCTCTTTTGCATCACAGCC
AGCAACAAACTATGTTTCTCGTATAGAAGAACGAGCGGCAGACCAATATGCTTTAGACATGACGAAGGACGGAAAATCTG
GTGTAAAGACGTTTCAATATTTATCAAAAACGAGCTTAAGCCAAGTAAATCCGCCTGCGTTAGTAAAGTTTTTCTTATAT
ACACACCCACCAATTTTTGAAAGAATTTATGCGTTTGAACAATATGAAAAAGAAAAGAAGCAGTAG

Upstream 100 bases:

>100_bases
AATAGAGGGTTCTTGAGCAATTTGCATAATAAGCTTGTTCTAATTTAGCATGTACGAACTTACAATAATAATAGACAGGC
AGCATAGAGGAGGGAATAGC

Downstream 100 bases:

>100_bases
TGTACTGCTTCTTTTCTTTTGGGTTATTCGAATTTTGGAAAATTATAGTGTATAATATATGAAATATTCAGTGAAATGTT
TAGGAGGTTAATATTTTGTT

Product: peptidase, M48 family

Products: NA

Alternate protein names: PSP23 [H]

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MRKVIGWSLFLYVGFALFIYWYLFGWNHELIPDMYKGTSADPETFMNARELTLSQDYSRVKNLLYFLATPLEWIILLFVL
VLGISKKFEKWSKETTKISVLQVAIYFFYLSLLTTVLALPMQWISRKVSVDYGISTQSTQSWIKDHVIGFWESYATMLIV
VAVLLWLIRKFPKRWWLAGWALSVPFTIFLTFIQPVVIDPLYNDFSTLKNKELETKILAIADKADIPAKHVYEVNMSEKT
NALNAYVTGIGPNARIVMWDTTLKQLKDKEILFIMAHEMGHYVMKHIYWGVASYMLLSFIGMYLISRIINMCIRKWGNTL
QISKAACFSILPLFFLISSVLSFASQPATNYVSRIEERAADQYALDMTKDGKSGVKTFQYLSKTSLSQVNPPALVKFFLY
THPPIFERIYAFEQYEKEKKQ

Sequences:

>Translated_421_residues
MRKVIGWSLFLYVGFALFIYWYLFGWNHELIPDMYKGTSADPETFMNARELTLSQDYSRVKNLLYFLATPLEWIILLFVL
VLGISKKFEKWSKETTKISVLQVAIYFFYLSLLTTVLALPMQWISRKVSVDYGISTQSTQSWIKDHVIGFWESYATMLIV
VAVLLWLIRKFPKRWWLAGWALSVPFTIFLTFIQPVVIDPLYNDFSTLKNKELETKILAIADKADIPAKHVYEVNMSEKT
NALNAYVTGIGPNARIVMWDTTLKQLKDKEILFIMAHEMGHYVMKHIYWGVASYMLLSFIGMYLISRIINMCIRKWGNTL
QISKAACFSILPLFFLISSVLSFASQPATNYVSRIEERAADQYALDMTKDGKSGVKTFQYLSKTSLSQVNPPALVKFFLY
THPPIFERIYAFEQYEKEKKQ
>Mature_421_residues
MRKVIGWSLFLYVGFALFIYWYLFGWNHELIPDMYKGTSADPETFMNARELTLSQDYSRVKNLLYFLATPLEWIILLFVL
VLGISKKFEKWSKETTKISVLQVAIYFFYLSLLTTVLALPMQWISRKVSVDYGISTQSTQSWIKDHVIGFWESYATMLIV
VAVLLWLIRKFPKRWWLAGWALSVPFTIFLTFIQPVVIDPLYNDFSTLKNKELETKILAIADKADIPAKHVYEVNMSEKT
NALNAYVTGIGPNARIVMWDTTLKQLKDKEILFIMAHEMGHYVMKHIYWGVASYMLLSFIGMYLISRIINMCIRKWGNTL
QISKAACFSILPLFFLISSVLSFASQPATNYVSRIEERAADQYALDMTKDGKSGVKTFQYLSKTSLSQVNPPALVKFFLY
THPPIFERIYAFEQYEKEKKQ

Specific function: Unknown

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Homo sapiens, GI18379366, Length=429, Percent_Identity=22.6107226107226, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17505484, Length=438, Percent_Identity=21.4611872146119, Blast_Score=88, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6322577, Length=306, Percent_Identity=27.1241830065359, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI19922414, Length=270, Percent_Identity=21.1111111111111, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: NA

Molecular weight: Translated: 48937; Mature: 48937

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS00142 ZINC_PROTEASE ; PS00678 WD_REPEATS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKVIGWSLFLYVGFALFIYWYLFGWNHELIPDMYKGTSADPETFMNARELTLSQDYSRV
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHH
KNLLYFLATPLEWIILLFVLVLGISKKFEKWSKETTKISVLQVAIYFFYLSLLTTVLALP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MQWISRKVSVDYGISTQSTQSWIKDHVIGFWESYATMLIVVAVLLWLIRKFPKRWWLAGW
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALSVPFTIFLTFIQPVVIDPLYNDFSTLKNKELETKILAIADKADIPAKHVYEVNMSEKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHEEECCCCCCHHHEEEECCCCCC
NALNAYVTGIGPNARIVMWDTTLKQLKDKEILFIMAHEMGHYVMKHIYWGVASYMLLSFI
CCHHEEEEEECCCCEEEEECCHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
GMYLISRIINMCIRKWGNTLQISKAACFSILPLFFLISSVLSFASQPATNYVSRIEERAA
HHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
DQYALDMTKDGKSGVKTFQYLSKTSLSQVNPPALVKFFLYTHPPIFERIYAFEQYEKEKK
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
Q
C
>Mature Secondary Structure
MRKVIGWSLFLYVGFALFIYWYLFGWNHELIPDMYKGTSADPETFMNARELTLSQDYSRV
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHH
KNLLYFLATPLEWIILLFVLVLGISKKFEKWSKETTKISVLQVAIYFFYLSLLTTVLALP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MQWISRKVSVDYGISTQSTQSWIKDHVIGFWESYATMLIVVAVLLWLIRKFPKRWWLAGW
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALSVPFTIFLTFIQPVVIDPLYNDFSTLKNKELETKILAIADKADIPAKHVYEVNMSEKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHEEECCCCCCHHHEEEECCCCCC
NALNAYVTGIGPNARIVMWDTTLKQLKDKEILFIMAHEMGHYVMKHIYWGVASYMLLSFI
CCHHEEEEEECCCCEEEEECCHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
GMYLISRIINMCIRKWGNTLQISKAACFSILPLFFLISSVLSFASQPATNYVSRIEERAA
HHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
DQYALDMTKDGKSGVKTFQYLSKTSLSQVNPPALVKFFLYTHPPIFERIYAFEQYEKEKK
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
Q
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 3145906 [H]