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The map label for this gene is sigM [H]

Identifier: 218902311

GI number: 218902311

Start: 1143788

End: 1144273

Strand: Reverse

Name: sigM [H]

Synonym: BCAH820_1193

Alternate gene names: 218902311

Gene position: 1144273-1143788 (Counterclockwise)

Preceding gene: 218902315

Following gene: 218902310

Centisome position: 21.58

GC content: 36.83

Gene sequence:

>486_bases
GTGAAACGTAAACAATCATTAGAAGACATTTATTCCGATCATATGCATGATTTATTTCGCTATCTTCTCTCCCTAACCGG
AGATTCTCATTTTGCTGAAGATCTCATGCAAGAAACATTTTACCGCATGCTCGTCCATATTGATTATTACAAAGGCGAAG
AAATTAGACCGTGGTTATTTACAATTGCCTACAACGCCTTTATCGATTGGTATCGAAAAGAGAAAAAATATAAAACAACA
GAGGTTGCAGAATTCCATTTACCAAACGTGCCAAGTACAGAACATGAATATTTCGTAAAATATGAGATTGCTAGTTGGTT
AGACCGTTTATCTTCTCTTCCGCTCGAGAGACGAAATGTTCTGTTACTACGAGATTACTACGGATTCTCGTATAAGGAAA
TAGCAGAAATGACTTGTCTCTCATTAGCAAAAGTGAAGATTGAATTACACCGGGGACGAAAAGAAACGAAAAGCATAAAG
GAGTGA

Upstream 100 bases:

>100_bases
GAATCTTATCCAATTCTTGACGTTTTTTACTATAATTCCATAAAAAATTGTAACTTTTTTATATGTATTTCGTTGTTATG
TATGAAGGGAGGGAAATGTA

Downstream 100 bases:

>100_bases
TACGGATGGGGTGTATAGAATTAAAAAAACTGTGGGAGAAATACGAAAATGGAACTCTCACGCATGATGAACAAGAACTG
TTAGAAAATCATATTGAGAC

Product: RNA polymerase sigma factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MKRKQSLEDIYSDHMHDLFRYLLSLTGDSHFAEDLMQETFYRMLVHIDYYKGEEIRPWLFTIAYNAFIDWYRKEKKYKTT
EVAEFHLPNVPSTEHEYFVKYEIASWLDRLSSLPLERRNVLLLRDYYGFSYKEIAEMTCLSLAKVKIELHRGRKETKSIK
E

Sequences:

>Translated_161_residues
MKRKQSLEDIYSDHMHDLFRYLLSLTGDSHFAEDLMQETFYRMLVHIDYYKGEEIRPWLFTIAYNAFIDWYRKEKKYKTT
EVAEFHLPNVPSTEHEYFVKYEIASWLDRLSSLPLERRNVLLLRDYYGFSYKEIAEMTCLSLAKVKIELHRGRKETKSIK
E
>Mature_161_residues
MKRKQSLEDIYSDHMHDLFRYLLSLTGDSHFAEDLMQETFYRMLVHIDYYKGEEIRPWLFTIAYNAFIDWYRKEKKYKTT
EVAEFHLPNVPSTEHEYFVKYEIASWLDRLSSLPLERRNVLLLRDYYGFSYKEIAEMTCLSLAKVKIELHRGRKETKSIK
E

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor may be involved in the maintenance of membrane and cell wall integrity in response to salt, acid and e

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014296
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 19581; Mature: 19581

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRKQSLEDIYSDHMHDLFRYLLSLTGDSHFAEDLMQETFYRMLVHIDYYKGEEIRPWLF
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
TIAYNAFIDWYRKEKKYKTTEVAEFHLPNVPSTEHEYFVKYEIASWLDRLSSLPLERRNV
HHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCHHEEEHHHHHHHHHHHCCCCCCCCE
LLLRDYYGFSYKEIAEMTCLSLAKVKIELHRGRKETKSIKE
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCC
>Mature Secondary Structure
MKRKQSLEDIYSDHMHDLFRYLLSLTGDSHFAEDLMQETFYRMLVHIDYYKGEEIRPWLF
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
TIAYNAFIDWYRKEKKYKTTEVAEFHLPNVPSTEHEYFVKYEIASWLDRLSSLPLERRNV
HHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCHHEEEHHHHHHHHHHHCCCCCCCCE
LLLRDYYGFSYKEIAEMTCLSLAKVKIELHRGRKETKSIKE
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 12775685; 10216858 [H]