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The map label for this gene is qacR [H]

Identifier: 218901591

GI number: 218901591

Start: 424717

End: 425298

Strand: Direct

Name: qacR [H]

Synonym: BCAH820_0433

Alternate gene names: 218901591

Gene position: 424717-425298 (Clockwise)

Preceding gene: 218901590

Following gene: 218901592

Centisome position: 8.01

GC content: 31.62

Gene sequence:

>582_bases
ATGAGAAGAAGTGCAGAAGAGATAAAGAAAGAAATTGCATATAAAGCAGAAATTTTATTTTCACAGAAGGGCTATGCAGC
CACATCTATGGAAGAGATTTGTGAAATTACAGAGAGAAGTAAAGGAAGCATTTATTATCACTTTAAAAGTAAAGAAGAAT
TATTTTTATTTGTAGTAAAGCAACATACGTATGATTGGCTTGAAAAATGGAATGAAAAAGAGAAGTTGTATAGTACTAGC
ACTGAGAAATTGTATGCCTTAGCAGAATATCATGTAGAGGATATACAACAACCTATTTCTAATGCAATAGAAGAATTTTC
TATGAGCCAAGTTGTAAGCAAAGAAATTTTGGATGAAATGTTAGCTTTAACTAGAGAATCGTATGTTATGTTTGAGACAT
TAATTGAAGCAGGCATACAGTCTGGAGAGTTTCGTGAAGATAATACGCGCGATCTTATGTATATTGTAAATGGATTATTA
TCAGGGCTGGGAGTACTTTATTACGAGTTAGATTATAAAGAATTGAAACGTATTTATAAAAAGGCGATAGATGTATTGTT
AAAAGGAATGGCAGCTGAATAA

Upstream 100 bases:

>100_bases
TTGAAAGTACATTTTCTTAAATAAGAAATATAGCCTCTTGTAATAGAGGTTTTTAATTTGTTATTATTAGACTGAACGGT
CGGTTTAAAGAGGTGTGAAT

Downstream 100 bases:

>100_bases
TAGGTCAGTTGCTTTTCTTACAAAATAAATTAGACCGAACGGTCGGTTTATGGAAGGAGAATAAAAATGAAAGCTTTATT
TAAAAATCGAGCATTTATGC

Product: transcriptional regulator, TetR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MRRSAEEIKKEIAYKAEILFSQKGYAATSMEEICEITERSKGSIYYHFKSKEELFLFVVKQHTYDWLEKWNEKEKLYSTS
TEKLYALAEYHVEDIQQPISNAIEEFSMSQVVSKEILDEMLALTRESYVMFETLIEAGIQSGEFREDNTRDLMYIVNGLL
SGLGVLYYELDYKELKRIYKKAIDVLLKGMAAE

Sequences:

>Translated_193_residues
MRRSAEEIKKEIAYKAEILFSQKGYAATSMEEICEITERSKGSIYYHFKSKEELFLFVVKQHTYDWLEKWNEKEKLYSTS
TEKLYALAEYHVEDIQQPISNAIEEFSMSQVVSKEILDEMLALTRESYVMFETLIEAGIQSGEFREDNTRDLMYIVNGLL
SGLGVLYYELDYKELKRIYKKAIDVLLKGMAAE
>Mature_193_residues
MRRSAEEIKKEIAYKAEILFSQKGYAATSMEEICEITERSKGSIYYHFKSKEELFLFVVKQHTYDWLEKWNEKEKLYSTS
TEKLYALAEYHVEDIQQPISNAIEEFSMSQVVSKEILDEMLALTRESYVMFETLIEAGIQSGEFREDNTRDLMYIVNGLL
SGLGVLYYELDYKELKRIYKKAIDVLLKGMAAE

Specific function: Transcriptional repressor of qacA. Binds to IR1, an unusually long 28 bp operator, which is located downstream from the qacA promoter and overlaps its transcription start site. QacR is induced from its IR1 site by binding to one of many structurally dissi

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR013571
- InterPro:   IPR001647 [H]

Pfam domain/function: PF08360 TetR_C_5; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22630; Mature: 22630

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRSAEEIKKEIAYKAEILFSQKGYAATSMEEICEITERSKGSIYYHFKSKEELFLFVVK
CCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEHHHHH
QHTYDWLEKWNEKEKLYSTSTEKLYALAEYHVEDIQQPISNAIEEFSMSQVVSKEILDEM
HHHHHHHHHHCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALTRESYVMFETLIEAGIQSGEFREDNTRDLMYIVNGLLSGLGVLYYELDYKELKRIYK
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KAIDVLLKGMAAE
HHHHHHHHHHCCC
>Mature Secondary Structure
MRRSAEEIKKEIAYKAEILFSQKGYAATSMEEICEITERSKGSIYYHFKSKEELFLFVVK
CCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEHHHHH
QHTYDWLEKWNEKEKLYSTSTEKLYALAEYHVEDIQQPISNAIEEFSMSQVVSKEILDEM
HHHHHHHHHHCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALTRESYVMFETLIEAGIQSGEFREDNTRDLMYIVNGLLSGLGVLYYELDYKELKRIYK
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KAIDVLLKGMAAE
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]