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The map label for this gene is ycbM [H]

Identifier: 218901476

GI number: 218901476

Start: 295632

End: 296645

Strand: Reverse

Name: ycbM [H]

Synonym: BCAH820_0316

Alternate gene names: 218901476

Gene position: 296645-295632 (Counterclockwise)

Preceding gene: 218901477

Following gene: 218901475

Centisome position: 5.59

GC content: 33.43

Gene sequence:

>1014_bases
TTGAAGATTGATAAAATCCTCTTCCTTATTTCATTACAACTTATCATTTACGGGCTTTTACATATACAAATGGATCCAAA
AGTAAAAATTTCTTTATTTATTACCCTTATCTTAATTACAATGTATCTCTTCTTTTCAAGAATACAATTTATTCAAAATC
ACAAATCAATAGACACTAAATTAAGTCGTGCACTAAAGGGGAATTTACAAACGAGATTATTCACAAGTAATGATCAATCG
TTACATAATATCGTTTTTTCAATAAACGAACTAATAGCTGAATTAGAAAAGGTTCGGATTAAAGCAAAAAGGTCTGAGGA
ATCTAGAAAACAACTTTTATCTAGTATCTCACACGATATCCGAACACCACTCACCTCCATTATTGGATATATCGACGCTT
TAAAAGATGGGGTTGCTGCTTCTGAAATAGAAAAGCAAGAATATCTTAAAATACTTTATATGAAATCAAATAACTTAAAG
CACCTAGTTGATGAAATATTCAATATGGCAAAGCTAGACGCTAATGAATTTCCACTAAAAGAAGAAAAACTCGACTTTTC
TGAAGTTACTAGAGAAGTTTTGATCGATTTTTTACCTGAAATCTCAAAACATAATATTAAACTGCAAGTTCTTATGCCAG
AGTCTACTTGTCCTATCATTGCAGATCACCTAAGCCTTATGCGGATTATAGGTAATTTAATGAAAAATGCCATTTATTAC
GGAAAGGATGGGAAAACAATAGGAGTCGAACTACTAGAAACGGATGCAGCATATGAACTTCTTATTTGGGACAAAGGCCC
TGGTATTCCAAAACATGATTTACAAAACGTATTTGAGCGAATGTACCGAAGCGAACAATCAAGAAACTCGTCTTTTGGTG
GTAGCGGGCTCGGCCTTTCTATTTCTAAAGCGCTCGTTGAGAAGAATGGTGGGCATATATGGGTTGAAAGTATTCCATGG
GAACGAACCACTTTTGGCTTTTCCATTCCAAAACACAATACTTTTAAGAAATAG

Upstream 100 bases:

>100_bases
CATATTCGAAAACTTAGAAAGAAAATAGAAATCGATCCTTCCAATCCAAAATTCATTCAAACTGTATGGGGAATTGGCTA
TAAGTTTGTAGGTGAAAAGC

Downstream 100 bases:

>100_bases
TTAAGAAATGATTAATATGCAGTTAAGCCTTCCTTTTTATCATGTAAGTAAGAACTTATAGAAAGTGGGTGTCTCCTATA
AACACAATTATAAAAACGAC

Product: putative sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MKIDKILFLISLQLIIYGLLHIQMDPKVKISLFITLILITMYLFFSRIQFIQNHKSIDTKLSRALKGNLQTRLFTSNDQS
LHNIVFSINELIAELEKVRIKAKRSEESRKQLLSSISHDIRTPLTSIIGYIDALKDGVAASEIEKQEYLKILYMKSNNLK
HLVDEIFNMAKLDANEFPLKEEKLDFSEVTREVLIDFLPEISKHNIKLQVLMPESTCPIIADHLSLMRIIGNLMKNAIYY
GKDGKTIGVELLETDAAYELLIWDKGPGIPKHDLQNVFERMYRSEQSRNSSFGGSGLGLSISKALVEKNGGHIWVESIPW
ERTTFGFSIPKHNTFKK

Sequences:

>Translated_337_residues
MKIDKILFLISLQLIIYGLLHIQMDPKVKISLFITLILITMYLFFSRIQFIQNHKSIDTKLSRALKGNLQTRLFTSNDQS
LHNIVFSINELIAELEKVRIKAKRSEESRKQLLSSISHDIRTPLTSIIGYIDALKDGVAASEIEKQEYLKILYMKSNNLK
HLVDEIFNMAKLDANEFPLKEEKLDFSEVTREVLIDFLPEISKHNIKLQVLMPESTCPIIADHLSLMRIIGNLMKNAIYY
GKDGKTIGVELLETDAAYELLIWDKGPGIPKHDLQNVFERMYRSEQSRNSSFGGSGLGLSISKALVEKNGGHIWVESIPW
ERTTFGFSIPKHNTFKK
>Mature_337_residues
MKIDKILFLISLQLIIYGLLHIQMDPKVKISLFITLILITMYLFFSRIQFIQNHKSIDTKLSRALKGNLQTRLFTSNDQS
LHNIVFSINELIAELEKVRIKAKRSEESRKQLLSSISHDIRTPLTSIIGYIDALKDGVAASEIEKQEYLKILYMKSNNLK
HLVDEIFNMAKLDANEFPLKEEKLDFSEVTREVLIDFLPEISKHNIKLQVLMPESTCPIIADHLSLMRIIGNLMKNAIYY
GKDGKTIGVELLETDAAYELLIWDKGPGIPKHDLQNVFERMYRSEQSRNSSFGGSGLGLSISKALVEKNGGHIWVESIPW
ERTTFGFSIPKHNTFKK

Specific function: Member of the two-component regulatory system ycbM/ycbL. Probably activates ycbL by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=264, Percent_Identity=28.030303030303, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1786912, Length=244, Percent_Identity=29.5081967213115, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1789149, Length=266, Percent_Identity=30.8270676691729, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788713, Length=249, Percent_Identity=28.5140562248996, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI48994928, Length=244, Percent_Identity=28.2786885245902, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI145693157, Length=238, Percent_Identity=24.7899159663866, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1786600, Length=228, Percent_Identity=27.6315789473684, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1786783, Length=252, Percent_Identity=26.5873015873016, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787894, Length=290, Percent_Identity=25.5172413793103, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790346, Length=267, Percent_Identity=25.0936329588015, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87082128, Length=312, Percent_Identity=24.0384615384615, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87081816, Length=247, Percent_Identity=24.2914979757085, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788279, Length=235, Percent_Identity=28.0851063829787, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788549, Length=305, Percent_Identity=22.2950819672131, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1790436, Length=225, Percent_Identity=24.8888888888889, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789808, Length=292, Percent_Identity=23.2876712328767, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 38623; Mature: 38623

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIDKILFLISLQLIIYGLLHIQMDPKVKISLFITLILITMYLFFSRIQFIQNHKSIDTK
CCHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSRALKGNLQTRLFTSNDQSLHNIVFSINELIAELEKVRIKAKRSEESRKQLLSSISHDI
HHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
RTPLTSIIGYIDALKDGVAASEIEKQEYLKILYMKSNNLKHLVDEIFNMAKLDANEFPLK
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHCCCCCCCCC
EEKLDFSEVTREVLIDFLPEISKHNIKLQVLMPESTCPIIADHLSLMRIIGNLMKNAIYY
HHCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCEEE
GKDGKTIGVELLETDAAYELLIWDKGPGIPKHDLQNVFERMYRSEQSRNSSFGGSGLGLS
CCCCCEEEHEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
ISKALVEKNGGHIWVESIPWERTTFGFSIPKHNTFKK
HHHHHHHCCCCEEEEECCCCCCCEECCCCCCCCCCCC
>Mature Secondary Structure
MKIDKILFLISLQLIIYGLLHIQMDPKVKISLFITLILITMYLFFSRIQFIQNHKSIDTK
CCHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSRALKGNLQTRLFTSNDQSLHNIVFSINELIAELEKVRIKAKRSEESRKQLLSSISHDI
HHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
RTPLTSIIGYIDALKDGVAASEIEKQEYLKILYMKSNNLKHLVDEIFNMAKLDANEFPLK
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHCCCCCCCCC
EEKLDFSEVTREVLIDFLPEISKHNIKLQVLMPESTCPIIADHLSLMRIIGNLMKNAIYY
HHCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCEEE
GKDGKTIGVELLETDAAYELLIWDKGPGIPKHDLQNVFERMYRSEQSRNSSFGGSGLGLS
CCCCCEEEHEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
ISKALVEKNGGHIWVESIPWERTTFGFSIPKHNTFKK
HHHHHHHCCCCEEEEECCCCCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]