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The map label for this gene is galE [C]

Identifier: 218901470

GI number: 218901470

Start: 283615

End: 284559

Strand: Direct

Name: galE [C]

Synonym: BCAH820_0308

Alternate gene names: 218901470

Gene position: 283615-284559 (Clockwise)

Preceding gene: 218901465

Following gene: 218901478

Centisome position: 5.35

GC content: 29.21

Gene sequence:

>945_bases
ATGGGGAAGAATAATTATTTAATAGTAGGTGGAAATAGTTTCATCGGTATTAACCTCGCATTAGGTTTATTGAAACAAGG
TCAAAATGTAAAGGTATTTTCCAGGCATTTAAATAATTTCCCTCAAAATATTATAAGTGAGGTCGAATTTATTAAAGGTG
ATTTAGCTAATGTTGAAGATATATATATAGCTTTAGCGAATGTGGATATTATTATTTATTTAGCTGCAACGTCTAATGTA
GCAACTTCAATTGAAGATGTTTTCGGAGATATAAACAGTAGCTTTTTTTTTCTTAATTTCATGGAAAGCGTTAAAAATTT
TCCTATTAAAAAAATTGTATTAGCATCTTCTGGAGGCACGGTTTATGGTGAACCTGAATATTTACCTATTGATGAGGACC
ATCCATTAAAACCACTTTCTCCTTATGGAATAACAAAAGTGTCGCTTGAAAATTATTTGTACTTTTATAAGAAAAAATAT
GGAATTGAATATGTTGTATGTAGATATTCTAATCCGTATGGAAAATATCAAAATCCTTTAAAGAAAGTTGGGGCAATAAA
TTGTTTTTTGTATCAGCATCTCAGTAATGAAAAGATTAATATATATGGGAATCCACAAGAGATTATTCGAGATTATATTT
ATATTGATGATTTAGTGGAAATCACTATACAACTATCACAATTAAATCGCTTGAAATCTTGTGTGTATAACATAGGGAGC
GGCAAGGGTCTCTCTTTAAAACGAATTATAGTAGAACTGGAGAAATTAACGGAAAGAAAAGTGGACTTTATCTGCTATAA
ACAAAAGCAAGAAAATGTTCAAAAAATCATTTTAAATATAGATAGGGTAAGACGAGAATGTAATTGGGAACCGAAAGTGG
ATTTCAAAAGTGGAATTAGATTAAATAAGCTATGGATTGAAGAGTTCTTATATAGTAAAAAATAA

Upstream 100 bases:

>100_bases
GGCATACAATTATAAGAAAAGAAATAATAAAAGTGTCCAAGTTCATTTATTTGTATTTCTAGGTGTGATAAGCAAAAATC
TTATTACTAGAGAGGATATT

Downstream 100 bases:

>100_bases
TAAGCCATGCCCTACTTCTGTATAAGTAGAGCATGGTTTATTATTTTATTTCTTTTTGTATTACCCAAAGGTCTTGATGT
TCCCACCAAAAACCTTCAGT

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MGKNNYLIVGGNSFIGINLALGLLKQGQNVKVFSRHLNNFPQNIISEVEFIKGDLANVEDIYIALANVDIIIYLAATSNV
ATSIEDVFGDINSSFFFLNFMESVKNFPIKKIVLASSGGTVYGEPEYLPIDEDHPLKPLSPYGITKVSLENYLYFYKKKY
GIEYVVCRYSNPYGKYQNPLKKVGAINCFLYQHLSNEKINIYGNPQEIIRDYIYIDDLVEITIQLSQLNRLKSCVYNIGS
GKGLSLKRIIVELEKLTERKVDFICYKQKQENVQKIILNIDRVRRECNWEPKVDFKSGIRLNKLWIEEFLYSKK

Sequences:

>Translated_314_residues
MGKNNYLIVGGNSFIGINLALGLLKQGQNVKVFSRHLNNFPQNIISEVEFIKGDLANVEDIYIALANVDIIIYLAATSNV
ATSIEDVFGDINSSFFFLNFMESVKNFPIKKIVLASSGGTVYGEPEYLPIDEDHPLKPLSPYGITKVSLENYLYFYKKKY
GIEYVVCRYSNPYGKYQNPLKKVGAINCFLYQHLSNEKINIYGNPQEIIRDYIYIDDLVEITIQLSQLNRLKSCVYNIGS
GKGLSLKRIIVELEKLTERKVDFICYKQKQENVQKIILNIDRVRRECNWEPKVDFKSGIRLNKLWIEEFLYSKK
>Mature_313_residues
GKNNYLIVGGNSFIGINLALGLLKQGQNVKVFSRHLNNFPQNIISEVEFIKGDLANVEDIYIALANVDIIIYLAATSNVA
TSIEDVFGDINSSFFFLNFMESVKNFPIKKIVLASSGGTVYGEPEYLPIDEDHPLKPLSPYGITKVSLENYLYFYKKKYG
IEYVVCRYSNPYGKYQNPLKKVGAINCFLYQHLSNEKINIYGNPQEIIRDYIYIDDLVEITIQLSQLNRLKSCVYNIGSG
KGLSLKRIIVELEKLTERKVDFICYKQKQENVQKIILNIDRVRRECNWEPKVDFKSGIRLNKLWIEEFLYSKK

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=317, Percent_Identity=25.2365930599369, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI56118217, Length=317, Percent_Identity=25.2365930599369, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI189083684, Length=317, Percent_Identity=25.2365930599369, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI42516563, Length=304, Percent_Identity=25.3289473684211, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI7657641, Length=335, Percent_Identity=24.4776119402985, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI48994969, Length=334, Percent_Identity=24.5508982035928, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1788353, Length=341, Percent_Identity=23.7536656891496, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17539532, Length=300, Percent_Identity=23.3333333333333, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71982035, Length=329, Percent_Identity=24.9240121580547, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71982038, Length=331, Percent_Identity=24.773413897281, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319493, Length=343, Percent_Identity=24.198250728863, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI19923002, Length=325, Percent_Identity=25.2307692307692, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21356223, Length=312, Percent_Identity=26.6025641025641, Blast_Score=81, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36151; Mature: 36020

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKNNYLIVGGNSFIGINLALGLLKQGQNVKVFSRHLNNFPQNIISEVEFIKGDLANVED
CCCCCEEEEECCCEEEHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCE
IYIALANVDIIIYLAATSNVATSIEDVFGDINSSFFFLNFMESVKNFPIKKIVLASSGGT
EEEEEECCEEEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEEEECCCCE
VYGEPEYLPIDEDHPLKPLSPYGITKVSLENYLYFYKKKYGIEYVVCRYSNPYGKYQNPL
EECCCCEECCCCCCCCCCCCCCCCEEEEHHHHHEEHHHHCCCEEEEEEECCCCCHHHHHH
KKVGAINCFLYQHLSNEKINIYGNPQEIIRDYIYIDDLVEITIQLSQLNRLKSCVYNIGS
HHHHHHHHEEEHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GKGLSLKRIIVELEKLTERKVDFICYKQKQENVQKIILNIDRVRRECNWEPKVDFKSGIR
CCCCHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCE
LNKLWIEEFLYSKK
EHHHHHHHHHHCCC
>Mature Secondary Structure 
GKNNYLIVGGNSFIGINLALGLLKQGQNVKVFSRHLNNFPQNIISEVEFIKGDLANVED
CCCCEEEEECCCEEEHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCE
IYIALANVDIIIYLAATSNVATSIEDVFGDINSSFFFLNFMESVKNFPIKKIVLASSGGT
EEEEEECCEEEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEEEECCCCE
VYGEPEYLPIDEDHPLKPLSPYGITKVSLENYLYFYKKKYGIEYVVCRYSNPYGKYQNPL
EECCCCEECCCCCCCCCCCCCCCCEEEEHHHHHEEHHHHCCCEEEEEEECCCCCHHHHHH
KKVGAINCFLYQHLSNEKINIYGNPQEIIRDYIYIDDLVEITIQLSQLNRLKSCVYNIGS
HHHHHHHHEEEHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GKGLSLKRIIVELEKLTERKVDFICYKQKQENVQKIILNIDRVRRECNWEPKVDFKSGIR
CCCCHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCE
LNKLWIEEFLYSKK
EHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]