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The map label for this gene is appC [H]

Identifier: 218901424

GI number: 218901424

Start: 222074

End: 222997

Strand: Direct

Name: appC [H]

Synonym: BCAH820_0243

Alternate gene names: 218901424

Gene position: 222074-222997 (Clockwise)

Preceding gene: 218901423

Following gene: 218901425

Centisome position: 4.19

GC content: 37.99

Gene sequence:

>924_bases
ATGGAGACTATTACACCAATAATAGAGAAAAAGAAAGAACGGAAAAAAAGAAACGAATCATCACCATGGCGCCAAGCGTA
TAAAAAAATTAAGAAAAATAAGATGGCGTTATATGGGTTATACGTTTTAATATTTATGTTTTTATTTAGTTTTATCGGTC
CAATCTTTTCACCATATGCTGATGGAAAAGTACAAGTAACACAAATTAATAAACCACCCAACCTATCACATTGGCTTGGA
ACAGACCAATTGGGACGAGATATTTTAACTAGACTTATGCAAGCGGGACGTATTTCATTAACGATTGGTTTAGCGTCGAT
GCTACTATCCGTTATACTAGGTGCTTTATTAGGAGCAATTGCTGGTTTTTATCGAGGTATTGTAGACCATTTAATTATGC
GTGTTGCAGATGTGTTAATGTCCATTCCGGGATTACCGTTACTTATTATAATGGGAGCAATCTTATCAGAATGGAAATTG
CCATCGGAATACCGTTTATATGTTGTAATGATTATTTTAAGTTTAGTAGGATGGCCAGGACTTGCCCGTCTTGTGAGAGG
ACAAATTTTAACGTTGCGGGAGCAAGCCTTTATGCAAGCAGCAGAAGTATTAGGATTAAAGGATTCTCGGAAAATTATTC
ATCATTTAGTTCCTAACGTCTTACCGTTGCTTATTGTTGTAGCAACTTTGGGTGTGGCTGGATCTATTCTAAGTGAATCC
GCACTAAGTTATTTAGGTCTCGGCGTTGTCCCACCTACACCATCATGGGGGAATATGATTAGTGCAGCGAACTCATTACT
TGATTTCCAAAAGCGCCCGTGGTTATGGATTCCGCCTGGTTTTGCAATCTTTATAACAGTTGTATCCATTAATTTACTTG
GTGATGCACTTCGTGATGCGTTAGATCCAAAGATGAGACGGTAG

Upstream 100 bases:

>100_bases
GATGTTTCTTTCATGTTTAACAATTATGGCAAATTTCTTAGCGGATATTGTATATGCGTTTGTTGATCCAAGAATTCGCT
TGAAGTAAGGGGGGAAAGAT

Downstream 100 bases:

>100_bases
GTGAGGGAATATGAGTAAAGCGGTAGTAGAGCTGAAAGATTTACAAACACACTTTCAGACAGAAGAAGGAACAGTAAAAG
CTGTGAATCATGTTAGTTTT

Product: oligopeptide ABC transporter, permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
METITPIIEKKKERKKRNESSPWRQAYKKIKKNKMALYGLYVLIFMFLFSFIGPIFSPYADGKVQVTQINKPPNLSHWLG
TDQLGRDILTRLMQAGRISLTIGLASMLLSVILGALLGAIAGFYRGIVDHLIMRVADVLMSIPGLPLLIIMGAILSEWKL
PSEYRLYVVMIILSLVGWPGLARLVRGQILTLREQAFMQAAEVLGLKDSRKIIHHLVPNVLPLLIVVATLGVAGSILSES
ALSYLGLGVVPPTPSWGNMISAANSLLDFQKRPWLWIPPGFAIFITVVSINLLGDALRDALDPKMRR

Sequences:

>Translated_307_residues
METITPIIEKKKERKKRNESSPWRQAYKKIKKNKMALYGLYVLIFMFLFSFIGPIFSPYADGKVQVTQINKPPNLSHWLG
TDQLGRDILTRLMQAGRISLTIGLASMLLSVILGALLGAIAGFYRGIVDHLIMRVADVLMSIPGLPLLIIMGAILSEWKL
PSEYRLYVVMIILSLVGWPGLARLVRGQILTLREQAFMQAAEVLGLKDSRKIIHHLVPNVLPLLIVVATLGVAGSILSES
ALSYLGLGVVPPTPSWGNMISAANSLLDFQKRPWLWIPPGFAIFITVVSINLLGDALRDALDPKMRR
>Mature_307_residues
METITPIIEKKKERKKRNESSPWRQAYKKIKKNKMALYGLYVLIFMFLFSFIGPIFSPYADGKVQVTQINKPPNLSHWLG
TDQLGRDILTRLMQAGRISLTIGLASMLLSVILGALLGAIAGFYRGIVDHLIMRVADVLMSIPGLPLLIIMGAILSEWKL
PSEYRLYVVMIILSLVGWPGLARLVRGQILTLREQAFMQAAEVLGLKDSRKIIHHLVPNVLPLLIVVATLGVAGSILSES
ALSYLGLGVVPPTPSWGNMISAANSLLDFQKRPWLWIPPGFAIFITVVSINLLGDALRDALDPKMRR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=293, Percent_Identity=36.1774744027304, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1787498, Length=305, Percent_Identity=35.7377049180328, Blast_Score=168, Evalue=3e-43,
Organism=Escherichia coli, GI1787760, Length=301, Percent_Identity=32.2259136212625, Blast_Score=161, Evalue=5e-41,
Organism=Escherichia coli, GI1789889, Length=248, Percent_Identity=39.9193548387097, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1789964, Length=295, Percent_Identity=36.6101694915254, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1788505, Length=235, Percent_Identity=31.4893617021277, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1787549, Length=285, Percent_Identity=30.1754385964912, Blast_Score=109, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34075; Mature: 34075

Theoretical pI: Translated: 10.69; Mature: 10.69

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCC
>Mature Secondary Structure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CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]