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The map label for this gene is maP1 [H]

Identifier: 218901337

GI number: 218901337

Start: 132202

End: 132912

Strand: Direct

Name: maP1 [H]

Synonym: BCAH820_0145

Alternate gene names: 218901337

Gene position: 132202-132912 (Clockwise)

Preceding gene: 218901336

Following gene: 218901338

Centisome position: 2.49

GC content: 43.04

Gene sequence:

>711_bases
ATGCGAGAAGCTGGCAGGATCGTTGCTTTAACTCATCAAGAGTTAAAACAACACATTACTCCAGGAATTACAACGAAAGA
GCTCGATCAAATAGCGGAAAAGACGATTCAAAAATATGGTGCTACGCCATCTTTTAAAGGATACAACGGATTTCCGGGGA
GCATATGTGCTTCTGTAAATGAAGAGCTTGTACACGGAATTCCAGGGAAGCGCAAGCTCAAAGAGGGCGATATCATCAGT
ATCGATATTGGTGCGAAATACAATGGGTACCATGGAGATTCTGCATGGACGTATCCAGTTGGAAACATTTCTGAATCTGT
TCAAAAGCTACTTGATGTCACAGAAAAATCGTTGTATCTTGGTCTAGAACAAGTAAAACCAGGCGAGAGATTATCAAATA
TCTCACATGCGGTTCAAACCCATGCTGAAGAGAATGGATTCTCGATCGTTAGGGAGTATGTTGGTCACGGAATCGGGCAA
GACTTACATGAGGACCCTCAAATCCCGCACTATGGTCCACCAAATAGAGGCCCTAGATTAAAGCCGGGAATGGTCATCTG
TGTTGAGCCGATGGTGAATCAAGGAAGACGATATGTAAAAACACTATCTGATGACTGGACAGTGGTAACGGTAGATGGTA
AATGGTGTGCCCATTTTGAGCACACGATTGCTCTTACAGAAGCAGGATACGAAATCCTTACCACTTTATAA

Upstream 100 bases:

>100_bases
ATGGTGAGCAAGATATCAATAAAGTATTTGCTGATATCGATGTTCTCATCGGAGGCTTAGCGTAATGATAATCTGCAAAA
CTCCTCGCGAGATAGAAATC

Downstream 100 bases:

>100_bases
GTAGCTGGCTCTCCGGGATTTCAGAGCAGTGTAAAATGTTACTGATTTGATGAAGGGAGAACTATTGAATGGCTAAAGAT
GATGTAATTGAAGTCGAAGG

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP 1; Peptidase M [H]

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MREAGRIVALTHQELKQHITPGITTKELDQIAEKTIQKYGATPSFKGYNGFPGSICASVNEELVHGIPGKRKLKEGDIIS
IDIGAKYNGYHGDSAWTYPVGNISESVQKLLDVTEKSLYLGLEQVKPGERLSNISHAVQTHAEENGFSIVREYVGHGIGQ
DLHEDPQIPHYGPPNRGPRLKPGMVICVEPMVNQGRRYVKTLSDDWTVVTVDGKWCAHFEHTIALTEAGYEILTTL

Sequences:

>Translated_236_residues
MREAGRIVALTHQELKQHITPGITTKELDQIAEKTIQKYGATPSFKGYNGFPGSICASVNEELVHGIPGKRKLKEGDIIS
IDIGAKYNGYHGDSAWTYPVGNISESVQKLLDVTEKSLYLGLEQVKPGERLSNISHAVQTHAEENGFSIVREYVGHGIGQ
DLHEDPQIPHYGPPNRGPRLKPGMVICVEPMVNQGRRYVKTLSDDWTVVTVDGKWCAHFEHTIALTEAGYEILTTL
>Mature_236_residues
MREAGRIVALTHQELKQHITPGITTKELDQIAEKTIQKYGATPSFKGYNGFPGSICASVNEELVHGIPGKRKLKEGDIIS
IDIGAKYNGYHGDSAWTYPVGNISESVQKLLDVTEKSLYLGLEQVKPGERLSNISHAVQTHAEENGFSIVREYVGHGIGQ
DLHEDPQIPHYGPPNRGPRLKPGMVICVEPMVNQGRRYVKTLSDDWTVVTVDGKWCAHFEHTIALTEAGYEILTTL

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=234, Percent_Identity=41.4529914529915, Blast_Score=188, Evalue=3e-48,
Organism=Homo sapiens, GI40385867, Length=214, Percent_Identity=40.6542056074766, Blast_Score=177, Evalue=1e-44,
Organism=Escherichia coli, GI1786364, Length=236, Percent_Identity=44.0677966101695, Blast_Score=211, Evalue=2e-56,
Organism=Escherichia coli, GI1789275, Length=210, Percent_Identity=25.7142857142857, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788728, Length=184, Percent_Identity=25, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71996291, Length=223, Percent_Identity=40.8071748878924, Blast_Score=181, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6323273, Length=219, Percent_Identity=47.4885844748858, Blast_Score=201, Evalue=1e-52,
Organism=Drosophila melanogaster, GI21355531, Length=234, Percent_Identity=41.025641025641, Blast_Score=191, Evalue=3e-49,
Organism=Drosophila melanogaster, GI24583427, Length=235, Percent_Identity=39.1489361702128, Blast_Score=175, Evalue=2e-44,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 26099; Mature: 26099

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREAGRIVALTHQELKQHITPGITTKELDQIAEKTIQKYGATPSFKGYNGFPGSICASVN
CCCCCCEEEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
EELVHGIPGKRKLKEGDIISIDIGAKYNGYHGDSAWTYPVGNISESVQKLLDVTEKSLYL
HHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHH
GLEQVKPGERLSNISHAVQTHAEENGFSIVREYVGHGIGQDLHEDPQIPHYGPPNRGPRL
HHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCC
KPGMVICVEPMVNQGRRYVKTLSDDWTVVTVDGKWCAHFEHTIALTEAGYEILTTL
CCCEEEEECHHHHCCHHHHHHCCCCEEEEEECCCEEEHHHHEEEEHHCCHHHHHCC
>Mature Secondary Structure
MREAGRIVALTHQELKQHITPGITTKELDQIAEKTIQKYGATPSFKGYNGFPGSICASVN
CCCCCCEEEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
EELVHGIPGKRKLKEGDIISIDIGAKYNGYHGDSAWTYPVGNISESVQKLLDVTEKSLYL
HHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHH
GLEQVKPGERLSNISHAVQTHAEENGFSIVREYVGHGIGQDLHEDPQIPHYGPPNRGPRL
HHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCC
KPGMVICVEPMVNQGRRYVKTLSDDWTVVTVDGKWCAHFEHTIALTEAGYEILTTL
CCCEEEEECHHHHCCHHHHHHCCCCEEEEEECCCEEEHHHHEEEEHHCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2113521; 8635744; 9384377 [H]