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The map label for this gene is trxB [H]

Identifier: 218884573

GI number: 218884573

Start: 1181170

End: 1182186

Strand: Reverse

Name: trxB [H]

Synonym: DKAM_1262

Alternate gene names: 218884573

Gene position: 1182186-1181170 (Counterclockwise)

Preceding gene: 218884575

Following gene: 218884572

Centisome position: 86.59

GC content: 44.54

Gene sequence:

>1017_bases
ATGGTGGTGTTTATGAGCTCCAGGTTCAGGATAACCGGGTTAACTACTACAATATATAAGAGCGGGGAAAAATACGATGT
CATAGTTATTGGGGGAGGGCCTGCAGGCTTAACAGCTGCACTATATAGTGCTAGATACGGGTTTAAGACGATAATTGTCA
CTAAGTTAGTGGGCGGCGCTGTATCAGAGGCCCCACTCGTAGACGACTACCCTGGAATACCTGATATACCCGGAAACGAC
CTAGTTGATAGATTTGTTAAACACGTAAAGAAGTATAATGTTCCCATAGTCATAGATGAAGTAATCAATCTAGTAAAGAA
ACCAGAGGAGAAAACATGGTGTGTAGAGCTACGAAGCGGTGGATCAATATGTGGCTACGCCATTATAATAGCTGTGGGAA
GCGAGAAAAGAAAGCTTAATGTCCCAGGGGAGAAGGAGTTAACCGGTAAGGGGGTATCATACTGTGCAACATGCGACGGC
CCCTTATTCAAGGATAAAATAGTTGCTGTAGTAGGCGGTGGGAATGCTGCTTTCACGTCAGCACTATATCTAGCCAAGAT
AGCTTCACACGTATACCTTATACATAGGAGAAGCGAGTTCCGCGCATTCAACGTATATGTTGAGACAGCTAGATCTAATC
CAAAGATAACTATCCTAACAAACACCATTATAAAAGAAATCATCGGCAAGAACCACTTGGAGGCGGTTAGAATACTGAAC
ACGGAATCAAACAAGGAGGAGATACTGAAAATTGATGGGCTCTTCATAGAAATAGGGTTGGAGCCCCCAGTCGAGTTCTT
CAGGAGAATAGGGTTGGAAACCGATGAGACGGGGAGAGCGAGAGTTAACATAGATAGGAGTACTAATCTGCCAGGCATAT
TCGTAGCAGGTGATGCTGCAGGCGGACCATATAAGTATAGATTTGAACAAATAATAACAGCGGCCGCTGATGGAGCGATC
GCTGCTGACGCCGCATGTAAATATATTTGCGCATTAAAGGGGCCATCGAGTACGTGA

Upstream 100 bases:

>100_bases
CATCTGTCCAACCTAGCGTAGTATACTCCATTTCAATCACTACATTGATATTAGGTTTCCCTAAAATATAAAAACAATAT
TTTACATCAATTAGTGATCC

Downstream 100 bases:

>100_bases
TAAATTATTTAAATCCCATCTAACTTCAATAAAAATACTGAAAAGAGGGCCCGTAGCTCAGCCTGGTAGAGCGCCCGGCT
CATAACCGGGTGGTCCGGGG

Product: Thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MVVFMSSRFRITGLTTTIYKSGEKYDVIVIGGGPAGLTAALYSARYGFKTIIVTKLVGGAVSEAPLVDDYPGIPDIPGND
LVDRFVKHVKKYNVPIVIDEVINLVKKPEEKTWCVELRSGGSICGYAIIIAVGSEKRKLNVPGEKELTGKGVSYCATCDG
PLFKDKIVAVVGGGNAAFTSALYLAKIASHVYLIHRRSEFRAFNVYVETARSNPKITILTNTIIKEIIGKNHLEAVRILN
TESNKEEILKIDGLFIEIGLEPPVEFFRRIGLETDETGRARVNIDRSTNLPGIFVAGDAAGGPYKYRFEQIITAAADGAI
AADAACKYICALKGPSST

Sequences:

>Translated_338_residues
MVVFMSSRFRITGLTTTIYKSGEKYDVIVIGGGPAGLTAALYSARYGFKTIIVTKLVGGAVSEAPLVDDYPGIPDIPGND
LVDRFVKHVKKYNVPIVIDEVINLVKKPEEKTWCVELRSGGSICGYAIIIAVGSEKRKLNVPGEKELTGKGVSYCATCDG
PLFKDKIVAVVGGGNAAFTSALYLAKIASHVYLIHRRSEFRAFNVYVETARSNPKITILTNTIIKEIIGKNHLEAVRILN
TESNKEEILKIDGLFIEIGLEPPVEFFRRIGLETDETGRARVNIDRSTNLPGIFVAGDAAGGPYKYRFEQIITAAADGAI
AADAACKYICALKGPSST
>Mature_338_residues
MVVFMSSRFRITGLTTTIYKSGEKYDVIVIGGGPAGLTAALYSARYGFKTIIVTKLVGGAVSEAPLVDDYPGIPDIPGND
LVDRFVKHVKKYNVPIVIDEVINLVKKPEEKTWCVELRSGGSICGYAIIIAVGSEKRKLNVPGEKELTGKGVSYCATCDG
PLFKDKIVAVVGGGNAAFTSALYLAKIASHVYLIHRRSEFRAFNVYVETARSNPKITILTNTIIKEIIGKNHLEAVRILN
TESNKEEILKIDGLFIEIGLEPPVEFFRRIGLETDETGRARVNIDRSTNLPGIFVAGDAAGGPYKYRFEQIITAAADGAI
AADAACKYICALKGPSST

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=320, Percent_Identity=35.625, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI87081763, Length=344, Percent_Identity=32.2674418604651, Blast_Score=153, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6320560, Length=320, Percent_Identity=35.625, Blast_Score=178, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6321898, Length=346, Percent_Identity=32.9479768786127, Blast_Score=176, Evalue=5e-45,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 36568; Mature: 36568

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVFMSSRFRITGLTTTIYKSGEKYDVIVIGGGPAGLTAALYSARYGFKTIIVTKLVGGA
CEEEEECCEEEEEEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCC
VSEAPLVDDYPGIPDIPGNDLVDRFVKHVKKYNVPIVIDEVINLVKKPEEKTWCVELRSG
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCCEEEEEECCC
GSICGYAIIIAVGSEKRKLNVPGEKELTGKGVSYCATCDGPLFKDKIVAVVGGGNAAFTS
CCEEEEEEEEEECCCCEEECCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEECCCHHHHH
ALYLAKIASHVYLIHRRSEFRAFNVYVETARSNPKITILTNTIIKEIIGKNHLEAVRILN
HHHHHHHHHHEEEEEECCCCEEEEEEEEECCCCCCEEEEEHHHHHHHHCCCCCEEEEEEC
TESNKEEILKIDGLFIEIGLEPPVEFFRRIGLETDETGRARVNIDRSTNLPGIFVAGDAA
CCCCCCCEEEEEEEEEEECCCCHHHHHHHCCCCCCCCCCEEEEECCCCCCCEEEEECCCC
GGPYKYRFEQIITAAADGAIAADAACKYICALKGPSST
CCCHHHHHHHHHHHHCCCCEEHHHHEEEEEEECCCCCC
>Mature Secondary Structure
MVVFMSSRFRITGLTTTIYKSGEKYDVIVIGGGPAGLTAALYSARYGFKTIIVTKLVGGA
CEEEEECCEEEEEEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCC
VSEAPLVDDYPGIPDIPGNDLVDRFVKHVKKYNVPIVIDEVINLVKKPEEKTWCVELRSG
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCCEEEEEECCC
GSICGYAIIIAVGSEKRKLNVPGEKELTGKGVSYCATCDGPLFKDKIVAVVGGGNAAFTS
CCEEEEEEEEEECCCCEEECCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEECCCHHHHH
ALYLAKIASHVYLIHRRSEFRAFNVYVETARSNPKITILTNTIIKEIIGKNHLEAVRILN
HHHHHHHHHHEEEEEECCCCEEEEEEEEECCCCCCEEEEEHHHHHHHHCCCCCEEEEEEC
TESNKEEILKIDGLFIEIGLEPPVEFFRRIGLETDETGRARVNIDRSTNLPGIFVAGDAA
CCCCCCCEEEEEEEEEEECCCCHHHHHHHCCCCCCCCCCEEEEECCCCCCCEEEEECCCC
GGPYKYRFEQIITAAADGAIAADAACKYICALKGPSST
CCCHHHHHHHHHHHHCCCCEEHHHHEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]