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The map label for this gene is fhuC [C]

Identifier: 218884559

GI number: 218884559

Start: 1169166

End: 1170974

Strand: Reverse

Name: fhuC [C]

Synonym: DKAM_1248

Alternate gene names: 218884559

Gene position: 1170974-1169166 (Counterclockwise)

Preceding gene: 218884560

Following gene: 218884558

Centisome position: 85.77

GC content: 45.0

Gene sequence:

>1809_bases
ATGGTTAGGACAGCTGTAGTGGATAGAAACTATTGTAAACCAGATAAATGTAGTCTTGAATGTATTAGGTTCTGCCCGGT
CAACAGGGGGAAGAGGAAGAAGGCCATAGAGTTAAGCAGCGACGGCAAGTATGTTATAATATACGAGGAGACATGTATAG
GATGCGGTATATGTGTTAAGAAATGCCCGTTTAACGCGATATCAATAGTTAATCTACCCGACGAGCTTGAGAAAATACTT
GTCCACAGGTATGGGGAAAACATGTTCAAACTATATAATCTACCAGCACCAAGGACAGGCGGCATCTTAGGCGTGATAGG
TAGAAATGGTGCCGGGAAGTCTACCAGTATAAAAATACTGGCTGGCCAGATAAAGCCGAATCTAGGCAACTATAGTAATC
CACCTGAATGGGATGCGATAATAAGGTACTTCAGAGGCAGCGAGCTACAATCATACTTCACGAAGCTCGCTAACAACGAG
ATCAAGGCGGTTGTGAAACCACAGTATATAGAGGCAGCTAGGAGAGTCTTAAAGGGAAGTGTTAGAGAGCTTATTATGAA
AGCTGATGAGAGAGGCTTATGGCGCGACATAATCGATGAACTTAACCTCTCTCATCTCCTTGATAGAAAGATAGGTGAGC
TAAGTGGTGGAGAGCTACAGAAATTCCTGGTCGCCGCTGTACTGGTTAAAAACGGTAATGCTTACTTCTTTGATGAACCC
TGCAGCTACCTAGATATAAGAGAGAGGATAAGGGTTGCTAGCGCTATAAGAGAGTTCAGCAACTATGAAAAAAACTACGT
TGTAATAGTGGAGCATGACTTAATGGTGCTGGACTATATGAGTGATAATATAGTAGTCGTCTATGGTGAACCCGGCGTAT
ACGGTATAGTATCGAAGCCCTATGGAACTAGGACAGGGATAAACCATTACCTCAAAGGGTATCTACCAGCTGAAAACATG
AGAATTAGGGATGAGGAGCTTAGATTCAGGATACATATGCAGGAGAGAAGGGATGTTGCCACCACATACCCTGTGCTTAA
ATGGGATGCTATAGAATACCGATATGAGTCATCAGGGTTTAAACTACGTGTAGAACCCGGGGAGGCATATGCAGGGGAAG
TACTTGGAATAGTGGGCCCTAATGGTGTTGGGAAAACCACCTTCCTGAAACTACTTAATGGGGAAATAGAGTCCCCTGAG
AAAGCCATATTAATATCTGCTGAGAAAGTGAGCGTGAAACCACAGGAGTTATCCCCTAAAGTATTCAGTGAGGAGACAGT
GATGGCTAACCTTAAATCGGCCTCGCCGGCAGCCCTCGATCCATCGTCATGGCTATACAACGAACTGGTGAGGAAACTTG
GATTAAATAAGATGCTTGATAGAAGGGTTGACGAGCTGAGCGGTGGAGAATTACAGAAACTAGCCGTAGCCGTTGCCCTT
GCAAGGGATGCCGATCTCTACTTCCTAGATGAGCCCTCAGCATACCTCGACGTCGAGGAAAGGATCACTACTGCGAAAAC
CATACGTAGAATGGTGGAGGAGAAAGGTAAGACTGCTCTTGTAGTGGAACACGACCTACTTATGCAGAACTATATCTCCG
ATAAAATAATAGTGTTCCTGGGTAAGCCCGGTATAGAGGGTTATGCCTCCGGCCCAGTGGATATTAGGACAGGCTTTAAT
AGGCTCCTCAAGGAACTAGATATAACTGTGAGGAGGGATAGTGAGAGCGGGCGTCCAAGGATAAATAAGCCGGGCTCTGT
GATGGATAGGGAGCAGAGGACTCGTGGGGAATATTATCTACCTGATTAA

Upstream 100 bases:

>100_bases
GCCGCTCTACCGAGATAAAAATACGTAACTATAATTTTTATATCTCATAGAGCGGGCAACCAGCCAAGTAATATATTAAT
ACTGCTAGAGGGGGGTGTAA

Downstream 100 bases:

>100_bases
ATCTTTTAAACAAATAATGAAATAAATAAAACTACTCTTATAGAAATATTTATTAGTTTTTCATATAAATACTTAAACAT
GGTGTAAGCATGGGTATGAA

Product: putative ATPase RIL

Products: ADP; phosphate; iron (III) hydroxamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 602; Mature: 602

Protein sequence:

>602_residues
MVRTAVVDRNYCKPDKCSLECIRFCPVNRGKRKKAIELSSDGKYVIIYEETCIGCGICVKKCPFNAISIVNLPDELEKIL
VHRYGENMFKLYNLPAPRTGGILGVIGRNGAGKSTSIKILAGQIKPNLGNYSNPPEWDAIIRYFRGSELQSYFTKLANNE
IKAVVKPQYIEAARRVLKGSVRELIMKADERGLWRDIIDELNLSHLLDRKIGELSGGELQKFLVAAVLVKNGNAYFFDEP
CSYLDIRERIRVASAIREFSNYEKNYVVIVEHDLMVLDYMSDNIVVVYGEPGVYGIVSKPYGTRTGINHYLKGYLPAENM
RIRDEELRFRIHMQERRDVATTYPVLKWDAIEYRYESSGFKLRVEPGEAYAGEVLGIVGPNGVGKTTFLKLLNGEIESPE
KAILISAEKVSVKPQELSPKVFSEETVMANLKSASPAALDPSSWLYNELVRKLGLNKMLDRRVDELSGGELQKLAVAVAL
ARDADLYFLDEPSAYLDVEERITTAKTIRRMVEEKGKTALVVEHDLLMQNYISDKIIVFLGKPGIEGYASGPVDIRTGFN
RLLKELDITVRRDSESGRPRINKPGSVMDREQRTRGEYYLPD

Sequences:

>Translated_602_residues
MVRTAVVDRNYCKPDKCSLECIRFCPVNRGKRKKAIELSSDGKYVIIYEETCIGCGICVKKCPFNAISIVNLPDELEKIL
VHRYGENMFKLYNLPAPRTGGILGVIGRNGAGKSTSIKILAGQIKPNLGNYSNPPEWDAIIRYFRGSELQSYFTKLANNE
IKAVVKPQYIEAARRVLKGSVRELIMKADERGLWRDIIDELNLSHLLDRKIGELSGGELQKFLVAAVLVKNGNAYFFDEP
CSYLDIRERIRVASAIREFSNYEKNYVVIVEHDLMVLDYMSDNIVVVYGEPGVYGIVSKPYGTRTGINHYLKGYLPAENM
RIRDEELRFRIHMQERRDVATTYPVLKWDAIEYRYESSGFKLRVEPGEAYAGEVLGIVGPNGVGKTTFLKLLNGEIESPE
KAILISAEKVSVKPQELSPKVFSEETVMANLKSASPAALDPSSWLYNELVRKLGLNKMLDRRVDELSGGELQKLAVAVAL
ARDADLYFLDEPSAYLDVEERITTAKTIRRMVEEKGKTALVVEHDLLMQNYISDKIIVFLGKPGIEGYASGPVDIRTGFN
RLLKELDITVRRDSESGRPRINKPGSVMDREQRTRGEYYLPD
>Mature_602_residues
MVRTAVVDRNYCKPDKCSLECIRFCPVNRGKRKKAIELSSDGKYVIIYEETCIGCGICVKKCPFNAISIVNLPDELEKIL
VHRYGENMFKLYNLPAPRTGGILGVIGRNGAGKSTSIKILAGQIKPNLGNYSNPPEWDAIIRYFRGSELQSYFTKLANNE
IKAVVKPQYIEAARRVLKGSVRELIMKADERGLWRDIIDELNLSHLLDRKIGELSGGELQKFLVAAVLVKNGNAYFFDEP
CSYLDIRERIRVASAIREFSNYEKNYVVIVEHDLMVLDYMSDNIVVVYGEPGVYGIVSKPYGTRTGINHYLKGYLPAENM
RIRDEELRFRIHMQERRDVATTYPVLKWDAIEYRYESSGFKLRVEPGEAYAGEVLGIVGPNGVGKTTFLKLLNGEIESPE
KAILISAEKVSVKPQELSPKVFSEETVMANLKSASPAALDPSSWLYNELVRKLGLNKMLDRRVDELSGGELQKLAVAVAL
ARDADLYFLDEPSAYLDVEERITTAKTIRRMVEEKGKTALVVEHDLLMQNYISDKIIVFLGKPGIEGYASGPVDIRTGFN
RLLKELDITVRRDSESGRPRINKPGSVMDREQRTRGEYYLPD

Specific function: Part Of The Binding-Protein-Dependent Transport System For Iron(III)-Ferrichrome. Probably Responsible For Energy Coupling To The Transport System. [C]

COG id: COG1245

COG function: function code R; Predicted ATPase, RNase L inhibitor (RLI) homolog

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI108773784, Length=602, Percent_Identity=43.3554817275748, Blast_Score=534, Evalue=1e-152,
Organism=Homo sapiens, GI108773782, Length=602, Percent_Identity=43.3554817275748, Blast_Score=534, Evalue=1e-152,
Organism=Escherichia coli, GI1786345, Length=196, Percent_Identity=29.5918367346939, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI87081782, Length=524, Percent_Identity=23.8549618320611, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1787112, Length=211, Percent_Identity=35.5450236966825, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1787758, Length=217, Percent_Identity=27.6497695852535, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1786563, Length=183, Percent_Identity=26.775956284153, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787500, Length=219, Percent_Identity=26.027397260274, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790467, Length=194, Percent_Identity=29.8969072164948, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87081834, Length=216, Percent_Identity=27.7777777777778, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87082267, Length=196, Percent_Identity=28.0612244897959, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786253, Length=185, Percent_Identity=27.5675675675676, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787029, Length=182, Percent_Identity=30.2197802197802, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787182, Length=513, Percent_Identity=24.5614035087719, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1790739, Length=236, Percent_Identity=23.3050847457627, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788225, Length=203, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87081791, Length=167, Percent_Identity=29.3413173652695, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI87081709, Length=179, Percent_Identity=29.0502793296089, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1789864, Length=215, Percent_Identity=26.5116279069767, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787370, Length=182, Percent_Identity=29.6703296703297, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1788761, Length=185, Percent_Identity=28.6486486486486, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1789751, Length=189, Percent_Identity=27.5132275132275, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1787712, Length=179, Percent_Identity=27.3743016759777, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1786703, Length=172, Percent_Identity=29.6511627906977, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17555800, Length=604, Percent_Identity=44.8675496688742, Blast_Score=547, Evalue=1e-156,
Organism=Caenorhabditis elegans, GI115533608, Length=186, Percent_Identity=29.0322580645161, Blast_Score=68, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320296, Length=611, Percent_Identity=46.3175122749591, Blast_Score=541, Evalue=1e-155,
Organism=Drosophila melanogaster, GI24661270, Length=604, Percent_Identity=44.7019867549669, Blast_Score=546, Evalue=1e-155,
Organism=Drosophila melanogaster, GI21355589, Length=604, Percent_Identity=44.7019867549669, Blast_Score=546, Evalue=1e-155,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR013283
- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR007209 [H]

Pfam domain/function: PF00005 ABC_tran; PF04068 RLI [H]

EC number: NA

Molecular weight: Translated: 67978; Mature: 67978

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: PS00198 4FE4S_FERREDOXIN ; PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRTAVVDRNYCKPDKCSLECIRFCPVNRGKRKKAIELSSDGKYVIIYEETCIGCGICVK
CCEEEEECCCCCCCCCCCHHEEEECCCCCCCCCCEEEECCCCCEEEEECCCCCCCCHHHH
KCPFNAISIVNLPDELEKILVHRYGENMFKLYNLPAPRTGGILGVIGRNGAGKSTSIKIL
HCCCCEEEEECCHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEECCCCCCCCEEEEE
AGQIKPNLGNYSNPPEWDAIIRYFRGSELQSYFTKLANNEIKAVVKPQYIEAARRVLKGS
EEEECCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHH
VRELIMKADERGLWRDIIDELNLSHLLDRKIGELSGGELQKFLVAAVLVKNGNAYFFDEP
HHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHEECCCEEEECCC
CSYLDIRERIRVASAIREFSNYEKNYVVIVEHDLMVLDYMSDNIVVVYGEPGVYGIVSKP
CCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEEECCCCEEEEECCCCEEEEECCC
YGTRTGINHYLKGYLPAENMRIRDEELRFRIHMQERRDVATTYPVLKWDAIEYRYESSGF
CCCCCCHHHHHHCCCCCCCCEECCCCEEEEEEEHHCCCHHHHCCEEEEEEEEEEECCCCC
KLRVEPGEAYAGEVLGIVGPNGVGKTTFLKLLNGEIESPEKAILISAEKVSVKPQELSPK
EEEECCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCEEEEEEHHEECCHHHCCCC
VFSEETVMANLKSASPAALDPSSWLYNELVRKLGLNKMLDRRVDELSGGELQKLAVAVAL
HHCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHH
ARDADLYFLDEPSAYLDVEERITTAKTIRRMVEEKGKTALVVEHDLLMQNYISDKIIVFL
CCCCCEEEECCCCCEEEHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHCCCEEEEEE
GKPGIEGYASGPVDIRTGFNRLLKELDITVRRDSESGRPRINKPGSVMDREQRTRGEYYL
ECCCCCCCCCCCEEHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCHHHHCCCCCCC
PD
CC
>Mature Secondary Structure
MVRTAVVDRNYCKPDKCSLECIRFCPVNRGKRKKAIELSSDGKYVIIYEETCIGCGICVK
CCEEEEECCCCCCCCCCCHHEEEECCCCCCCCCCEEEECCCCCEEEEECCCCCCCCHHHH
KCPFNAISIVNLPDELEKILVHRYGENMFKLYNLPAPRTGGILGVIGRNGAGKSTSIKIL
HCCCCEEEEECCHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEECCCCCCCCEEEEE
AGQIKPNLGNYSNPPEWDAIIRYFRGSELQSYFTKLANNEIKAVVKPQYIEAARRVLKGS
EEEECCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHH
VRELIMKADERGLWRDIIDELNLSHLLDRKIGELSGGELQKFLVAAVLVKNGNAYFFDEP
HHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHEECCCEEEECCC
CSYLDIRERIRVASAIREFSNYEKNYVVIVEHDLMVLDYMSDNIVVVYGEPGVYGIVSKP
CCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEEECCCCEEEEECCCCEEEEECCC
YGTRTGINHYLKGYLPAENMRIRDEELRFRIHMQERRDVATTYPVLKWDAIEYRYESSGF
CCCCCCHHHHHHCCCCCCCCEECCCCEEEEEEEHHCCCHHHHCCEEEEEEEEEEECCCCC
KLRVEPGEAYAGEVLGIVGPNGVGKTTFLKLLNGEIESPEKAILISAEKVSVKPQELSPK
EEEECCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCEEEEEEHHEECCHHHCCCC
VFSEETVMANLKSASPAALDPSSWLYNELVRKLGLNKMLDRRVDELSGGELQKLAVAVAL
HHCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHH
ARDADLYFLDEPSAYLDVEERITTAKTIRRMVEEKGKTALVVEHDLLMQNYISDKIIVFL
CCCCCEEEECCCCCEEEHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHCCCEEEEEE
GKPGIEGYASGPVDIRTGFNRLLKELDITVRRDSESGRPRINKPGSVMDREQRTRGEYYL
ECCCCCCCCCCCEEHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCHHHHCCCCCCC
PD
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron (III) hydroxamate [Periplasm]; H2O [C]

Specific reaction: ATP + iron (III) hydroxamate [Periplasm] + H2O = ADP + phosphate + iron (III) hydroxamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]