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The map label for this gene is pcnB1 [H]

Identifier: 218884495

GI number: 218884495

Start: 1104974

End: 1105738

Strand: Reverse

Name: pcnB1 [H]

Synonym: DKAM_1184

Alternate gene names: 218884495

Gene position: 1105738-1104974 (Counterclockwise)

Preceding gene: 218884500

Following gene: 218884493

Centisome position: 80.99

GC content: 45.36

Gene sequence:

>765_bases
GTGGGTCAATTGTTTAAAGCCGTCTACCCTAACGCATCGAAGATGAAATATATCACACAGGCTATCGCGAAAATCACTGA
TGAGGCACCAATCTACGTGACACAGGAAGGATTAGAGGTCAGGGTATTAAGTCCTGATAAATCGATGCTTAGCATAGTTA
GAATACCTGCCATGAGCTTCGAGGAATATAGTGTTGAAGGGGAGGAGTCCTTCATTGTCGCATCAACGGATTTAAACAAG
ATAATGAGGCGTGGGACAAGAAACGATGTATTAGTTATGGAGCTTGACAGGGCTGGCAATGTGTTGAATATGGTGTTTAG
GGATAGGAAAACAGGGCTTGAAAGGGTTTTCCAGCTAGAGCTACTGCCGAGAACACCGGAGCCGGTTCCAGAATTAAACA
TTGAGCTGGGGGTAGTCGTTAAAATGATGGCTGAAGACTATATGAATATAATCGGGGACTTGAAAACCATCGGTGAGGAA
GCAATATTCGCTTATGAGGAAAACGAGCTAAAGATATCCTCCTCGGAGCAACAGAAGGAGTATGTAGGCGTATTCACAGA
GGGATCGCCACTCCTATACGTGTATTCATCGGTTGAGAAAGCAAGGGCGGTCTACAGTATTGACCTGCTAGCTGTAACAG
TCAAACCGGCTTCGGCATCTAAGCAGGTGACTATATCCTTTGACACGGATAAACCAGTGAAAGTAGAGTATGAGCTAGCT
GGGGGAGGCCAACTAATATACTGGGTTGTCCCAAGAGTAGGCTAG

Upstream 100 bases:

>100_bases
ATATTTTGGGCTAATAAATTCGACGGTTATGACTACCTCCCTACATTGATCCCTTATGGATGAATATATTTTAATCCACG
TATAAAATTAGTTATCAGGG

Downstream 100 bases:

>100_bases
CTGGTTAGAGGGGGTTATCTAGGCTGAGGGCGTCCTGCTCTCACTGCTTAATTTACCAAGTAGCTCCATTAACAGCCTCC
TACGCTCCTCGGGGCTGGCA

Product: DNA polymerase sliding clamp B1

Products: NA

Alternate protein names: Proliferating cell nuclear antigen homolog B1; PCNA B1 [H]

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MGQLFKAVYPNASKMKYITQAIAKITDEAPIYVTQEGLEVRVLSPDKSMLSIVRIPAMSFEEYSVEGEESFIVASTDLNK
IMRRGTRNDVLVMELDRAGNVLNMVFRDRKTGLERVFQLELLPRTPEPVPELNIELGVVVKMMAEDYMNIIGDLKTIGEE
AIFAYEENELKISSSEQQKEYVGVFTEGSPLLYVYSSVEKARAVYSIDLLAVTVKPASASKQVTISFDTDKPVKVEYELA
GGGQLIYWVVPRVG

Sequences:

>Translated_254_residues
MGQLFKAVYPNASKMKYITQAIAKITDEAPIYVTQEGLEVRVLSPDKSMLSIVRIPAMSFEEYSVEGEESFIVASTDLNK
IMRRGTRNDVLVMELDRAGNVLNMVFRDRKTGLERVFQLELLPRTPEPVPELNIELGVVVKMMAEDYMNIIGDLKTIGEE
AIFAYEENELKISSSEQQKEYVGVFTEGSPLLYVYSSVEKARAVYSIDLLAVTVKPASASKQVTISFDTDKPVKVEYELA
GGGQLIYWVVPRVG
>Mature_253_residues
GQLFKAVYPNASKMKYITQAIAKITDEAPIYVTQEGLEVRVLSPDKSMLSIVRIPAMSFEEYSVEGEESFIVASTDLNKI
MRRGTRNDVLVMELDRAGNVLNMVFRDRKTGLERVFQLELLPRTPEPVPELNIELGVVVKMMAEDYMNIIGDLKTIGEEA
IFAYEENELKISSSEQQKEYVGVFTEGSPLLYVYSSVEKARAVYSIDLLAVTVKPASASKQVTISFDTDKPVKVEYELAG
GGQLIYWVVPRVG

Specific function: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication [H]

COG id: COG0592

COG function: function code L; DNA polymerase sliding clamp subunit (PCNA homolog)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PCNA family [H]

Homologues:

Organism=Homo sapiens, GI33239451, Length=266, Percent_Identity=24.4360902255639, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI4505641, Length=266, Percent_Identity=24.4360902255639, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000730
- InterPro:   IPR022659
- InterPro:   IPR022648 [H]

Pfam domain/function: PF00705 PCNA_N [H]

EC number: NA

Molecular weight: Translated: 28436; Mature: 28305

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQLFKAVYPNASKMKYITQAIAKITDEAPIYVTQEGLEVRVLSPDKSMLSIVRIPAMSF
CCCCHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEECCCHHHHHHHCCCCCCC
EEYSVEGEESFIVASTDLNKIMRRGTRNDVLVMELDRAGNVLNMVFRDRKTGLERVFQLE
HHCCCCCCCEEEEEECCHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHEEEEE
LLPRTPEPVPELNIELGVVVKMMAEDYMNIIGDLKTIGEEAIFAYEENELKISSSEQQKE
ECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEECCCCCCCE
YVGVFTEGSPLLYVYSSVEKARAVYSIDLLAVTVKPASASKQVTISFDTDKPVKVEYELA
EEEEEECCCCEEEEEECHHHHHHEEEEEEEEEEEECCCCCCEEEEEECCCCCEEEEEEEC
GGGQLIYWVVPRVG
CCCEEEEEEECCCC
>Mature Secondary Structure 
GQLFKAVYPNASKMKYITQAIAKITDEAPIYVTQEGLEVRVLSPDKSMLSIVRIPAMSF
CCCHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEECCCHHHHHHHCCCCCCC
EEYSVEGEESFIVASTDLNKIMRRGTRNDVLVMELDRAGNVLNMVFRDRKTGLERVFQLE
HHCCCCCCCEEEEEECCHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHEEEEE
LLPRTPEPVPELNIELGVVVKMMAEDYMNIIGDLKTIGEEAIFAYEENELKISSSEQQKE
ECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEECCCCCCCE
YVGVFTEGSPLLYVYSSVEKARAVYSIDLLAVTVKPASASKQVTISFDTDKPVKVEYELA
EEEEEECCCCEEEEEECHHHHHHEEEEEEEEEEEECCCCCCEEEEEECCCCCEEEEEEEC
GGGQLIYWVVPRVG
CCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10382966 [H]