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The map label for this gene is gpt [H]

Identifier: 218884356

GI number: 218884356

Start: 992096

End: 992788

Strand: Direct

Name: gpt [H]

Synonym: DKAM_1045

Alternate gene names: 218884356

Gene position: 992096-992788 (Clockwise)

Preceding gene: 218884355

Following gene: 218884357

Centisome position: 72.67

GC content: 44.59

Gene sequence:

>693_bases
GTGATAGAAATGCCTAGGGTTAGAACTCATTTAGTTACATGGGATGAGATAGTAGAGTGGTCAATGAACTTGGCCAGGAT
TATAAGGGAAAACGGGTACAAACCCGAGCTCGTTGTAGCTGTTTCAAGAGGGGGATTCGTCCCCGCGAGGCTCATATGCG
ATTTCCTGGGCGTGGAAAACCTGGCCAGTATTCAAAGCCAGCACTGGACTGAGGCAGCTAAAGCCGAGGAAAGAGCCATA
CTCAAATATCCCTTCAAGCTCGACGCATCAGGGATGAAGGTACTGGTTGTGGATGACATCGTGGATACAGGCGAGACATT
AAGGTTGGCTAGGGATTATATAAGGGATAGCTGGAGCCCACTCGAGGTTAAAACAGCAGCACTGCAATGGATAAGCCCTG
TAGCTAAGTATAAGCCAGACTACTACTACTTAGAGGTAAAGGAGTGGATATGGTTCCAATACCCCTGGACCAGGCTGGAG
GATACTTATCAATTCATTAAAAGAATGATGAGCGAAACATATAAGGAAACTGGTAAAAAAGAATGGAGCTATAAGGAGAT
AATAGATGGCTTCAAGGAATGGTATGGGATAGATGTTGGAGATATGTATTATAGAGAGGCGCTAAGGATTCTACTAGAGA
AAGACATCGTAAAGTATGATCCAGGCAGAGACAAGTACTTATTGAAGGTGTGA

Upstream 100 bases:

>100_bases
TAATTGTTCACTCTTCCAACCAGGTTATTAAGGTATACTGTCCTTGATTCTCTGGGCCGGGTTCTAATCTTTTTAAGTAT
ACATATGTTATTATATTTAC

Downstream 100 bases:

>100_bases
GAAATGCTGGTCGAGCCCTCTGTGAAAGCCAGCATAGCTATTATAGGGGGAAGCGGGGTATACGATCTCCCAGGTCTAAG
TAATATAAGAGAGTACAAGG

Product: putative phosphoribosyltransferase

Products: NA

Alternate protein names: Xanthine-guanine phosphoribosyltransferase; XGPRT [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MIEMPRVRTHLVTWDEIVEWSMNLARIIRENGYKPELVVAVSRGGFVPARLICDFLGVENLASIQSQHWTEAAKAEERAI
LKYPFKLDASGMKVLVVDDIVDTGETLRLARDYIRDSWSPLEVKTAALQWISPVAKYKPDYYYLEVKEWIWFQYPWTRLE
DTYQFIKRMMSETYKETGKKEWSYKEIIDGFKEWYGIDVGDMYYREALRILLEKDIVKYDPGRDKYLLKV

Sequences:

>Translated_230_residues
MIEMPRVRTHLVTWDEIVEWSMNLARIIRENGYKPELVVAVSRGGFVPARLICDFLGVENLASIQSQHWTEAAKAEERAI
LKYPFKLDASGMKVLVVDDIVDTGETLRLARDYIRDSWSPLEVKTAALQWISPVAKYKPDYYYLEVKEWIWFQYPWTRLE
DTYQFIKRMMSETYKETGKKEWSYKEIIDGFKEWYGIDVGDMYYREALRILLEKDIVKYDPGRDKYLLKV
>Mature_230_residues
MIEMPRVRTHLVTWDEIVEWSMNLARIIRENGYKPELVVAVSRGGFVPARLICDFLGVENLASIQSQHWTEAAKAEERAI
LKYPFKLDASGMKVLVVDDIVDTGETLRLARDYIRDSWSPLEVKTAALQWISPVAKYKPDYYYLEVKEWIWFQYPWTRLE
DTYQFIKRMMSETYKETGKKEWSYKEIIDGFKEWYGIDVGDMYYREALRILLEKDIVKYDPGRDKYLLKV

Specific function: Acts on guanine, xanthine and to a lesser extent hypoxanthine [H]

COG id: COG2236

COG function: function code R; Predicted phosphoribosyltransferases

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.22 [H]

Molecular weight: Translated: 27334; Mature: 27334

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEMPRVRTHLVTWDEIVEWSMNLARIIRENGYKPELVVAVSRGGFVPARLICDFLGVEN
CCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCHHH
LASIQSQHWTEAAKAEERAILKYPFKLDASGMKVLVVDDIVDTGETLRLARDYIRDSWSP
HHHHHHHHHHHHHHHHHHHHEECCCEECCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCC
LEVKTAALQWISPVAKYKPDYYYLEVKEWIWFQYPWTRLEDTYQFIKRMMSETYKETGKK
HHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCC
EWSYKEIIDGFKEWYGIDVGDMYYREALRILLEKDIVKYDPGRDKYLLKV
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEC
>Mature Secondary Structure
MIEMPRVRTHLVTWDEIVEWSMNLARIIRENGYKPELVVAVSRGGFVPARLICDFLGVEN
CCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCHHH
LASIQSQHWTEAAKAEERAILKYPFKLDASGMKVLVVDDIVDTGETLRLARDYIRDSWSP
HHHHHHHHHHHHHHHHHHHHEECCCEECCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCC
LEVKTAALQWISPVAKYKPDYYYLEVKEWIWFQYPWTRLEDTYQFIKRMMSETYKETGKK
HHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCC
EWSYKEIIDGFKEWYGIDVGDMYYREALRILLEKDIVKYDPGRDKYLLKV
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]