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The map label for this gene is nuoN [H]

Identifier: 218884267

GI number: 218884267

Start: 903095

End: 904642

Strand: Reverse

Name: nuoN [H]

Synonym: DKAM_0956

Alternate gene names: 218884267

Gene position: 904642-903095 (Counterclockwise)

Preceding gene: 218884268

Following gene: 218884266

Centisome position: 66.26

GC content: 45.67

Gene sequence:

>1548_bases
ATGCCAGGCGGTTTACCCGTGGAGGCGCTACCAGCTTTAACTGTTTACTTATTGATAGGTGGCTCTTTCACGCTCATATT
ATTTAAGGCTTTAAAGGTGAGGGCATCTATTCTACGTGTTTACAGTGGTTTGTACCTTGTTTTCGCGGCTGCTTCAGCGT
TGCTAATATATCTCGAGGCAAGGAGAGGCGTTTTAATCTATGTCGTTGGAGGCTTTCCCTCATTGATAGGCATAGCTTAC
GAGGTTGACTTATTCTCTGCATCGATGGGATTAATCATAGCTGTACTCTCACTGGCTATGTACCCGCTTCTAGGCATCCT
TGACTTGAATCTCAACGAGTACACTATGTCTCTCTACCTGGGTCTGGTTGCAGGGCTCCTTGGTGTAACTTATACGGGCG
ACTTATTCAACTCATTCGTCATGCTGGAGGTCTTCACCATATCTATGCTTGGATTGATTGCGGCAAGCAATACTGTTAGA
GCCTACAAAGCAGCATTAAGGTATGGGTTGCTGGCATTTGTAACGGGCCTTATTTACTTCCTCGGGGCTACTTTAATGTA
TTTTGCTGTTGGAGCATTAAACATGGGTTATATAGCTACATGGAACACCCGACTCTTTATACTGGGTAAAGCCATATATG
CCTCTCTACCTCTTGAAAGCGTTATACTATTCATACTTATACTCATGACATGGAGCCTTATCGCTGAGGAAGCTCTAGTA
CCTCTACATTTCTGGCTTCCCGAAGCCTATAGCGTGGCTTCTCCAGCTATAGCCGGCCTACTAGCCGGGGTTGGTGAGGC
AGTTGGCTATTACTTGCTGCTGAGGCTTTACTATACATTGTACTCGGCGATCCCGGAGCCCGTGGCCTTAATGCTCAGGG
TTCTTGGAATGATCACAATAATTGTCGGTGGATTCGGCATCTTATACTCGGATAGATTGCTCAGTATAATATCGTATAGT
GTAATACTTGATTCCGGATATATAGCGATAGCAGCATCTCTGGGTCCATCGGGTGTTCCAGTAGTATTAGCATATGTTGT
AGCTCATGCTGTTGTGAAACCTCTTCTCTTCATTACTAGTGGATGGGCGGTCTCCAACAGAGGCGGTGATAAACTAGGTG
ATTTACAGGGAGTCTTCAGGGGAAGCAGAATAATGCAGCTTGGATTTGTGACGGGTGCTGTGGCAGTTATAGGTATACCT
CCAACGGTATTGTTCTCAGCAAAGCTGGAGCTCTACATCAACTTATTTAATGCAATGAGCACTGATCCATCACTCCTATT
ATTACTGATTGTGGCCCTATTGGGAAGCGGGCTAGCCTTAGCCGGCTTCATTAAGGCCGTGTCAGTGACTGTTCTCTCAT
ATAGCGATAACATAGGGAAGCCCAGAGGGGTGGTTGAAGCCTATGTTTTAGTCTTTACGATAATAGTGGTTGCTCTTGGA
GTCGCATATAGTATCATGGCCCAGGGATTCATTGAGCCCGCCTCCCAATCACTTATATACGAGAGGTTCAACTACGTTAT
GAAAGCCCTTTCAGCTATCGGGAGGTGA

Upstream 100 bases:

>100_bases
AGGGCTTGATAGATTTATGTATGCAATGGTGTATTGGAAACATTTATATATTCCCCATATTTTTAGTTAGACCTGACTAA
CGTTAGGTTTGGTGAATATA

Downstream 100 bases:

>100_bases
GTATGAAATGCTTGAGAGGATTGCTAGATGGGCTTACGCTAGAAGCCTCTGGATGATACACTACTGTTCAGCATGTGGAG
CAGTAGAGTTCCCGCCATTA

Product: Hydrogenase 4, component F or formate hydrogen lyase subunit 3

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 515; Mature: 514

Protein sequence:

>515_residues
MPGGLPVEALPALTVYLLIGGSFTLILFKALKVRASILRVYSGLYLVFAAASALLIYLEARRGVLIYVVGGFPSLIGIAY
EVDLFSASMGLIIAVLSLAMYPLLGILDLNLNEYTMSLYLGLVAGLLGVTYTGDLFNSFVMLEVFTISMLGLIAASNTVR
AYKAALRYGLLAFVTGLIYFLGATLMYFAVGALNMGYIATWNTRLFILGKAIYASLPLESVILFILILMTWSLIAEEALV
PLHFWLPEAYSVASPAIAGLLAGVGEAVGYYLLLRLYYTLYSAIPEPVALMLRVLGMITIIVGGFGILYSDRLLSIISYS
VILDSGYIAIAASLGPSGVPVVLAYVVAHAVVKPLLFITSGWAVSNRGGDKLGDLQGVFRGSRIMQLGFVTGAVAVIGIP
PTVLFSAKLELYINLFNAMSTDPSLLLLLIVALLGSGLALAGFIKAVSVTVLSYSDNIGKPRGVVEAYVLVFTIIVVALG
VAYSIMAQGFIEPASQSLIYERFNYVMKALSAIGR

Sequences:

>Translated_515_residues
MPGGLPVEALPALTVYLLIGGSFTLILFKALKVRASILRVYSGLYLVFAAASALLIYLEARRGVLIYVVGGFPSLIGIAY
EVDLFSASMGLIIAVLSLAMYPLLGILDLNLNEYTMSLYLGLVAGLLGVTYTGDLFNSFVMLEVFTISMLGLIAASNTVR
AYKAALRYGLLAFVTGLIYFLGATLMYFAVGALNMGYIATWNTRLFILGKAIYASLPLESVILFILILMTWSLIAEEALV
PLHFWLPEAYSVASPAIAGLLAGVGEAVGYYLLLRLYYTLYSAIPEPVALMLRVLGMITIIVGGFGILYSDRLLSIISYS
VILDSGYIAIAASLGPSGVPVVLAYVVAHAVVKPLLFITSGWAVSNRGGDKLGDLQGVFRGSRIMQLGFVTGAVAVIGIP
PTVLFSAKLELYINLFNAMSTDPSLLLLLIVALLGSGLALAGFIKAVSVTVLSYSDNIGKPRGVVEAYVLVFTIIVVALG
VAYSIMAQGFIEPASQSLIYERFNYVMKALSAIGR
>Mature_514_residues
PGGLPVEALPALTVYLLIGGSFTLILFKALKVRASILRVYSGLYLVFAAASALLIYLEARRGVLIYVVGGFPSLIGIAYE
VDLFSASMGLIIAVLSLAMYPLLGILDLNLNEYTMSLYLGLVAGLLGVTYTGDLFNSFVMLEVFTISMLGLIAASNTVRA
YKAALRYGLLAFVTGLIYFLGATLMYFAVGALNMGYIATWNTRLFILGKAIYASLPLESVILFILILMTWSLIAEEALVP
LHFWLPEAYSVASPAIAGLLAGVGEAVGYYLLLRLYYTLYSAIPEPVALMLRVLGMITIIVGGFGILYSDRLLSIISYSV
ILDSGYIAIAASLGPSGVPVVLAYVVAHAVVKPLLFITSGWAVSNRGGDKLGDLQGVFRGSRIMQLGFVTGAVAVIGIPP
TVLFSAKLELYINLFNAMSTDPSLLLLLIVALLGSGLALAGFIKAVSVTVLSYSDNIGKPRGVVEAYVLVFTIIVVALGV
AYSIMAQGFIEPASQSLIYERFNYVMKALSAIGR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0651

COG function: function code CP; Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788831, Length=173, Percent_Identity=30.0578034682081, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1788829, Length=325, Percent_Identity=24.9230769230769, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750
- InterPro:   IPR003918 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 54965; Mature: 54833

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGGLPVEALPALTVYLLIGGSFTLILFKALKVRASILRVYSGLYLVFAAASALLIYLEA
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RRGVLIYVVGGFPSLIGIAYEVDLFSASMGLIIAVLSLAMYPLLGILDLNLNEYTMSLYL
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GLVAGLLGVTYTGDLFNSFVMLEVFTISMLGLIAASNTVRAYKAALRYGLLAFVTGLIYF
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LGATLMYFAVGALNMGYIATWNTRLFILGKAIYASLPLESVILFILILMTWSLIAEEALV
HHHHHHHHHHHHCCCCEEEEECCEEEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
PLHFWLPEAYSVASPAIAGLLAGVGEAVGYYLLLRLYYTLYSAIPEPVALMLRVLGMITI
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
IVGGFGILYSDRLLSIISYSVILDSGYIAIAASLGPSGVPVVLAYVVAHAVVKPLLFITS
HHHHHHHHHHHHHHHHHHHHHHEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCC
GWAVSNRGGDKLGDLQGVFRGSRIMQLGFVTGAVAVIGIPPTVLFSAKLELYINLFNAMS
CCEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHCC
TDPSLLLLLIVALLGSGLALAGFIKAVSVTVLSYSDNIGKPRGVVEAYVLVFTIIVVALG
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
VAYSIMAQGFIEPASQSLIYERFNYVMKALSAIGR
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PGGLPVEALPALTVYLLIGGSFTLILFKALKVRASILRVYSGLYLVFAAASALLIYLEA
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RRGVLIYVVGGFPSLIGIAYEVDLFSASMGLIIAVLSLAMYPLLGILDLNLNEYTMSLYL
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GLVAGLLGVTYTGDLFNSFVMLEVFTISMLGLIAASNTVRAYKAALRYGLLAFVTGLIYF
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LGATLMYFAVGALNMGYIATWNTRLFILGKAIYASLPLESVILFILILMTWSLIAEEALV
HHHHHHHHHHHHCCCCEEEEECCEEEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
PLHFWLPEAYSVASPAIAGLLAGVGEAVGYYLLLRLYYTLYSAIPEPVALMLRVLGMITI
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
IVGGFGILYSDRLLSIISYSVILDSGYIAIAASLGPSGVPVVLAYVVAHAVVKPLLFITS
HHHHHHHHHHHHHHHHHHHHHHEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCC
GWAVSNRGGDKLGDLQGVFRGSRIMQLGFVTGAVAVIGIPPTVLFSAKLELYINLFNAMS
CCEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHCC
TDPSLLLLLIVALLGSGLALAGFIKAVSVTVLSYSDNIGKPRGVVEAYVLVFTIIVVALG
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
VAYSIMAQGFIEPASQSLIYERFNYVMKALSAIGR
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA