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The map label for this gene is nuoH [H]

Identifier: 218884256

GI number: 218884256

Start: 896590

End: 897567

Strand: Reverse

Name: nuoH [H]

Synonym: DKAM_0945

Alternate gene names: 218884256

Gene position: 897567-896590 (Counterclockwise)

Preceding gene: 218884257

Following gene: 218884254

Centisome position: 65.75

GC content: 42.64

Gene sequence:

>978_bases
ATGATGGATCCAATAATATTCCTTATACAAGCCCTCATATATCCAGGCCTATTATTCGCAATAGCATTCATAATATTTAC
ACAGTGGCTCAGTAGAAAAATCACCGCCAGGATACAGTATAGAAGAGGGCCGGTTTACGTTGGTCCAGCTGGACTACTTC
AACCATTAGCTGATTTATTGAAGCTTGTAATGAAGAAGGACCTGGTCAACAAATATAGTTTAAGAGCAAGCCCGCTTATC
GTGATATCCATTGTAATAGGTGCATTGATAACGGTGTTCTCGGTAACACCAATCGCGATAAAACCCTTATACGCCGATTT
CGATATAATTATACTGTTATACCTGTTACTATTAATACCGTTCGGACTAGCCTATCTAGCCGTAGCCCATCCAAACCCGT
ATACTGTAATAGGTGCTGGACGCTACATAGCATTATTATTCTCTAGTGAACCAGCCTACGCTATCTCGATGCTTGTGCCA
GTAATAATCGCATCGAGATACTTTAATGCAGGATATTCGCTCTACCCTACATCACTGGTATCTCCCCAGCTCTGGACTAT
TAACCCGTTAAAAACGCTCTCAATGGTACTGGCATCTATTGCGGGTTTCCTAGGGTTGATGAGTATATTAATGATTAAAC
CCTTCGATACCCCGGAGGCTGAGTCGGAGCTATACTGGGGTATATTCACTGAGTTAGGAGGCCCTAGGCTAGCTCTTGGA
TTCTTCGCTAAGTTTGCTGAGAAAATAGTCTACCCATTAATATACGTACTGCTCTTCCTTGGAGGAGCCTGGCCGTTCAA
CGATGACTGGATACTGGGAACGCTTGTAATACTGGTTAAGACGACAATAGTATTTGCTGTGTTAACAATAATCGATGCCT
CGCTGCCACGTTACAAGCCTGAGCAAGCAGTGAGATATCTATGGAAATACCTCTATCCATTATCAATAATATCCCTTATC
TTAGCGCTAGCCCCTTGA

Upstream 100 bases:

>100_bases
TGGAGAGGAGTATTGCATCGTATTTATCGGACTGGTACTTCATAGGGCTTCTACTACTAATCGCATTAGTTGTTGTGTTG
CTTATACTTGGGTGATCGAT

Downstream 100 bases:

>100_bases
AAATGACTAATAGTGAAACAAAGACTTCCGGGGACTTGAGTTTTTACTGGACCCGTGGTCATGGTGGATTATTGAAAAAC
CATGATAGGTCTGCTGGTCT

Product: respiratory-chain NADH dehydrogenase subunit 1

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MMDPIIFLIQALIYPGLLFAIAFIIFTQWLSRKITARIQYRRGPVYVGPAGLLQPLADLLKLVMKKDLVNKYSLRASPLI
VISIVIGALITVFSVTPIAIKPLYADFDIIILLYLLLLIPFGLAYLAVAHPNPYTVIGAGRYIALLFSSEPAYAISMLVP
VIIASRYFNAGYSLYPTSLVSPQLWTINPLKTLSMVLASIAGFLGLMSILMIKPFDTPEAESELYWGIFTELGGPRLALG
FFAKFAEKIVYPLIYVLLFLGGAWPFNDDWILGTLVILVKTTIVFAVLTIIDASLPRYKPEQAVRYLWKYLYPLSIISLI
LALAP

Sequences:

>Translated_325_residues
MMDPIIFLIQALIYPGLLFAIAFIIFTQWLSRKITARIQYRRGPVYVGPAGLLQPLADLLKLVMKKDLVNKYSLRASPLI
VISIVIGALITVFSVTPIAIKPLYADFDIIILLYLLLLIPFGLAYLAVAHPNPYTVIGAGRYIALLFSSEPAYAISMLVP
VIIASRYFNAGYSLYPTSLVSPQLWTINPLKTLSMVLASIAGFLGLMSILMIKPFDTPEAESELYWGIFTELGGPRLALG
FFAKFAEKIVYPLIYVLLFLGGAWPFNDDWILGTLVILVKTTIVFAVLTIIDASLPRYKPEQAVRYLWKYLYPLSIISLI
LALAP
>Mature_325_residues
MMDPIIFLIQALIYPGLLFAIAFIIFTQWLSRKITARIQYRRGPVYVGPAGLLQPLADLLKLVMKKDLVNKYSLRASPLI
VISIVIGALITVFSVTPIAIKPLYADFDIIILLYLLLLIPFGLAYLAVAHPNPYTVIGAGRYIALLFSSEPAYAISMLVP
VIIASRYFNAGYSLYPTSLVSPQLWTINPLKTLSMVLASIAGFLGLMSILMIKPFDTPEAESELYWGIFTELGGPRLALG
FFAKFAEKIVYPLIYVLLFLGGAWPFNDDWILGTLVILVKTTIVFAVLTIIDASLPRYKPEQAVRYLWKYLYPLSIISLI
LALAP

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=299, Percent_Identity=27.7591973244147, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1788618, Length=316, Percent_Identity=30.0632911392405, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI87082115, Length=236, Percent_Identity=30.0847457627119, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1789077, Length=311, Percent_Identity=26.3665594855305, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 36171; Mature: 36171

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDPIIFLIQALIYPGLLFAIAFIIFTQWLSRKITARIQYRRGPVYVGPAGLLQPLADLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEECCHHHHHHHHHHH
KLVMKKDLVNKYSLRASPLIVISIVIGALITVFSVTPIAIKPLYADFDIIILLYLLLLIP
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHEEHHHCCHHHHHHHHHHHHHH
FGLAYLAVAHPNPYTVIGAGRYIALLFSSEPAYAISMLVPVIIASRYFNAGYSLYPTSLV
HHHHHHHEECCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHC
SPQLWTINPLKTLSMVLASIAGFLGLMSILMIKPFDTPEAESELYWGIFTELGGPRLALG
CCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHH
FFAKFAEKIVYPLIYVLLFLGGAWPFNDDWILGTLVILVKTTIVFAVLTIIDASLPRYKP
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
EQAVRYLWKYLYPLSIISLILALAP
HHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMDPIIFLIQALIYPGLLFAIAFIIFTQWLSRKITARIQYRRGPVYVGPAGLLQPLADLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEECCHHHHHHHHHHH
KLVMKKDLVNKYSLRASPLIVISIVIGALITVFSVTPIAIKPLYADFDIIILLYLLLLIP
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHEEHHHCCHHHHHHHHHHHHHH
FGLAYLAVAHPNPYTVIGAGRYIALLFSSEPAYAISMLVPVIIASRYFNAGYSLYPTSLV
HHHHHHHEECCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHC
SPQLWTINPLKTLSMVLASIAGFLGLMSILMIKPFDTPEAESELYWGIFTELGGPRLALG
CCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHH
FFAKFAEKIVYPLIYVLLFLGGAWPFNDDWILGTLVILVKTTIVFAVLTIIDASLPRYKP
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
EQAVRYLWKYLYPLSIISLILALAP
HHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA