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The map label for this gene is purP [H]

Identifier: 218883840

GI number: 218883840

Start: 496620

End: 497729

Strand: Direct

Name: purP [H]

Synonym: DKAM_0529

Alternate gene names: 218883840

Gene position: 496620-497729 (Clockwise)

Preceding gene: 218883839

Following gene: 218883841

Centisome position: 36.38

GC content: 44.23

Gene sequence:

>1110_bases
TTGAGTACTAGGTTTAACCCTAGGGACCTAATTGCACATTATGAGCCGGGGAGAATAGCTATTGCAGCTGTTGCAAGCCA
TTCAGCACTGGATGTATTCGATGGAGCTAAAGATGAGGGTTTCAGAACCATAGCTGTCTGCCAGGTTGGAAGAGAGAAGA
CATATATGAGGTTAAATACGGTGATCGACGAGTATATAATATTAGATAGCTTTAAAGACGTTGTGAAACCCTCGGCAATG
GATTACCTGGCTGGCAAGAACGCTATTATAGTGCCTAACCGTAGTTTCTCAGTATATGTAGGGTATGATGCTATCGAAAG
CGAGTTGAGGATCCCGGTATTTGGCAACAAGTATCTCCTCAGATACGAGGAAAGGACCGGACCTAAGAACTACTATATGC
TTCTCCAGGAAGCTGGGATAAGACATCCAAGGATCTATAGGGATCCAGATGAGATAGATAGGCCTGTAATAGTTAAGATA
CCACATGCAAGGAAAAGGGTTGAACGTGGATTCTTTATAGCAGTGGATAGGGACGACTTTTACAAGAAGATGAAGAGGCT
GGTTAATAATAGTGTTATAAGAAAAGAAGATATCGTTTCAGCCTCGATAGAGGAGCTAGTGGTGGGTGCCCACTTCAACG
TCAACTACTTCCATAGTATAGCCAGGAAGAGGGTGGAGTTGCTGAGCATAGACCGCAGGATACAGAGCAACCTAGATGGC
TTCCTACATCTAACAGCTAGTATACAGTTGGAGCTTGAAGAATACTTGGATGTAGAGATGATTGAAGTGGGGCACGAGCC
CGCAACCATAAGGGAGTCACTACTTGAGAAGCTATTTGATTATGGCGATAGATTCGTGGATGCATGCAAGAGGATCGTGG
AGCCCGGTGTCATAGGGCCTTTCGCACTTCAATTAATTGTAACCAAGGATCTTGATATAGTAGTGTATGATGTAGCACCA
CGTATAGGCGGAGGCACAAATATCTATATGGGGATTGGTAGCCAGTACAGTAAGCTCTATTTCGGGAAACCAATCAGTAT
GGGGAGGAGGATCGCTATCGAGATACATGAATGCATTGAATCAGGTTGCTTACAGGAGATAGTCACGTGA

Upstream 100 bases:

>100_bases
AGCCGGCTCATTGAGGAACACGGTTTTCACCCATATGTAATCGGGGAGATTGTTGAGGGGAACGGATTGGTTCATGTGAT
AACTCCGTATGGTGATATAG

Downstream 100 bases:

>100_bases
GGTGTTCGCATGTCTGGAAGCATTTGCCCACTTGAATGGAGATATGGTTCAACCGAGATGAGAAGGGTGTTTTCCAGGAG
AAATATAGTGGATACATACA

Product: 5-formaminoimidazole-4-carboxamide-1-(beta)-D- ribofuranosyl 5'-monophosphate synthetase-like protein

Products: NA

Alternate protein names: 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate--formate ligase [H]

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MSTRFNPRDLIAHYEPGRIAIAAVASHSALDVFDGAKDEGFRTIAVCQVGREKTYMRLNTVIDEYIILDSFKDVVKPSAM
DYLAGKNAIIVPNRSFSVYVGYDAIESELRIPVFGNKYLLRYEERTGPKNYYMLLQEAGIRHPRIYRDPDEIDRPVIVKI
PHARKRVERGFFIAVDRDDFYKKMKRLVNNSVIRKEDIVSASIEELVVGAHFNVNYFHSIARKRVELLSIDRRIQSNLDG
FLHLTASIQLELEEYLDVEMIEVGHEPATIRESLLEKLFDYGDRFVDACKRIVEPGVIGPFALQLIVTKDLDIVVYDVAP
RIGGGTNIYMGIGSQYSKLYFGKPISMGRRIAIEIHECIESGCLQEIVT

Sequences:

>Translated_369_residues
MSTRFNPRDLIAHYEPGRIAIAAVASHSALDVFDGAKDEGFRTIAVCQVGREKTYMRLNTVIDEYIILDSFKDVVKPSAM
DYLAGKNAIIVPNRSFSVYVGYDAIESELRIPVFGNKYLLRYEERTGPKNYYMLLQEAGIRHPRIYRDPDEIDRPVIVKI
PHARKRVERGFFIAVDRDDFYKKMKRLVNNSVIRKEDIVSASIEELVVGAHFNVNYFHSIARKRVELLSIDRRIQSNLDG
FLHLTASIQLELEEYLDVEMIEVGHEPATIRESLLEKLFDYGDRFVDACKRIVEPGVIGPFALQLIVTKDLDIVVYDVAP
RIGGGTNIYMGIGSQYSKLYFGKPISMGRRIAIEIHECIESGCLQEIVT
>Mature_368_residues
STRFNPRDLIAHYEPGRIAIAAVASHSALDVFDGAKDEGFRTIAVCQVGREKTYMRLNTVIDEYIILDSFKDVVKPSAMD
YLAGKNAIIVPNRSFSVYVGYDAIESELRIPVFGNKYLLRYEERTGPKNYYMLLQEAGIRHPRIYRDPDEIDRPVIVKIP
HARKRVERGFFIAVDRDDFYKKMKRLVNNSVIRKEDIVSASIEELVVGAHFNVNYFHSIARKRVELLSIDRRIQSNLDGF
LHLTASIQLELEEYLDVEMIEVGHEPATIRESLLEKLFDYGDRFVDACKRIVEPGVIGPFALQLIVTKDLDIVVYDVAPR
IGGGTNIYMGIGSQYSKLYFGKPISMGRRIAIEIHECIESGCLQEIVT

Specific function: Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates [H]

COG id: COG1759

COG function: function code R; ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR009720
- InterPro:   IPR010672
- InterPro:   IPR013817 [H]

Pfam domain/function: PF06849 DUF1246; PF06973 DUF1297 [H]

EC number: NA

Molecular weight: Translated: 42088; Mature: 41957

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS50975 ATP_GRASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTRFNPRDLIAHYEPGRIAIAAVASHSALDVFDGAKDEGFRTIAVCQVGREKTYMRLNT
CCCCCCHHHHHEECCCCCEEEEEECCCCCHHHCCCCCCCCCEEEEEEECCCCHHHHHHHH
VIDEYIILDSFKDVVKPSAMDYLAGKNAIIVPNRSFSVYVGYDAIESELRIPVFGNKYLL
HHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEECCCEEEEEEHHHHCCCEEEEEECCCEEE
RYEERTGPKNYYMLLQEAGIRHPRIYRDPDEIDRPVIVKIPHARKRVERGFFIAVDRDDF
EEECCCCCCHHEEEEECCCCCCCCCCCCHHHCCCCEEEECCCHHHHHCCCEEEEECCHHH
YKKMKRLVNNSVIRKEDIVSASIEELVVGAHFNVNYFHSIARKRVELLSIDRRIQSNLDG
HHHHHHHHCCCCCCHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCE
FLHLTASIQLELEEYLDVEMIEVGHEPATIRESLLEKLFDYGDRFVDACKRIVEPGVIGP
EEEEEEEEEEEEHHHCCEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCH
FALQLIVTKDLDIVVYDVAPRIGGGTNIYMGIGSQYSKLYFGKPISMGRRIAIEIHECIE
HHEEEEEECCCCEEEEECCCCCCCCCEEEEECCCCCCCEECCCCCCCCCEEEEEHHHHHH
SGCLQEIVT
HHHHHHHCC
>Mature Secondary Structure 
STRFNPRDLIAHYEPGRIAIAAVASHSALDVFDGAKDEGFRTIAVCQVGREKTYMRLNT
CCCCCHHHHHEECCCCCEEEEEECCCCCHHHCCCCCCCCCEEEEEEECCCCHHHHHHHH
VIDEYIILDSFKDVVKPSAMDYLAGKNAIIVPNRSFSVYVGYDAIESELRIPVFGNKYLL
HHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEECCCEEEEEEHHHHCCCEEEEEECCCEEE
RYEERTGPKNYYMLLQEAGIRHPRIYRDPDEIDRPVIVKIPHARKRVERGFFIAVDRDDF
EEECCCCCCHHEEEEECCCCCCCCCCCCHHHCCCCEEEECCCHHHHHCCCEEEEECCHHH
YKKMKRLVNNSVIRKEDIVSASIEELVVGAHFNVNYFHSIARKRVELLSIDRRIQSNLDG
HHHHHHHHCCCCCCHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCE
FLHLTASIQLELEEYLDVEMIEVGHEPATIRESLLEKLFDYGDRFVDACKRIVEPGVIGP
EEEEEEEEEEEEHHHCCEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCH
FALQLIVTKDLDIVVYDVAPRIGGGTNIYMGIGSQYSKLYFGKPISMGRRIAIEIHECIE
HHEEEEEECCCCEEEEECCCCCCCCCEEEEECCCCCCCEECCCCCCCCCEEEEEHHHHHH
SGCLQEIVT
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA