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The map label for this gene is rpiA [H]

Identifier: 218883775

GI number: 218883775

Start: 432859

End: 433590

Strand: Reverse

Name: rpiA [H]

Synonym: DKAM_0464

Alternate gene names: 218883775

Gene position: 433590-432859 (Counterclockwise)

Preceding gene: 218883777

Following gene: 218883774

Centisome position: 31.76

GC content: 48.36

Gene sequence:

>732_bases
ATGGATGCTTCAAGCATTATTGAGCAGGCGAAGTTAAATGCCTGTGACTATGCCTGTAGGCATCTATATGAGAAATATGG
TGATGCCTTGGTAGTAGGGGTTGGCACGGGTTCGACTGTGAAACTGTTGATCACTAAGTGCAGGGATTTCTTCACCGAGA
GAATACTGGTCCCCTCATCCCACGACACACTCCTCCACCTGGTATCCCTCGGACTTAACACGGCTGTCGATCCAGCTGGA
GTCGATGATATCGATCTATACATTGATGGAGCCGATGAGGTTTCGGGAAAACTAGACCTCGTCAAGGGGAGGGGTGGGGC
CTTCCTAAGGGAGAAATCCCTTGCTGTACGTAGTAGGGTTAGGATGTATGTGGTTGACTACACTAAGTATACTGGGCTTA
ACCACATATACGTTAAACCTATTCCGATAGAGGTTGTACCTGTCTCGGTGAAATATGTTATCAGGAAGCTACAGGAGCTA
GGGTATGGCGAGCCATTGCTGAGAATGGGTACTGGGAAGGATGGCCCAGTGGTCTCTGACAATGGGAACTTTATCGTTGA
CTACAGGCTTTTAAAGCCTGTTGAAGACCCTTTATCTCTCCACAACACGCTTAAACTAGTACATGGAGTGATTGAAACAG
GTATATTCCCTTCAAACCTGGTTGACATCGTTGTGGTCGGGGAACCAGCCGGGGTCAGGGTGCTTGGAAAAAACACTGGT
GGGAGGGAGTAG

Upstream 100 bases:

>100_bases
CTTGTCATGCTTTATTACTCGATAAATAATTAATCTTACTCTATCATTTATATTCAACGTATGTCGGCTTTCAACTAACC
GGGAGCACCTGGTGCTTGAT

Downstream 100 bases:

>100_bases
GGGTAGTGAAGGGGGTTACACACCTGCTTCTCGGTGCTGCAGTAGGCTTATACATAGGTTATGATGCATTATCCTCCATC
GCGGCCTCCATGATATCCGG

Product: ribose 5-phosphate isomerase

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MDASSIIEQAKLNACDYACRHLYEKYGDALVVGVGTGSTVKLLITKCRDFFTERILVPSSHDTLLHLVSLGLNTAVDPAG
VDDIDLYIDGADEVSGKLDLVKGRGGAFLREKSLAVRSRVRMYVVDYTKYTGLNHIYVKPIPIEVVPVSVKYVIRKLQEL
GYGEPLLRMGTGKDGPVVSDNGNFIVDYRLLKPVEDPLSLHNTLKLVHGVIETGIFPSNLVDIVVVGEPAGVRVLGKNTG
GRE

Sequences:

>Translated_243_residues
MDASSIIEQAKLNACDYACRHLYEKYGDALVVGVGTGSTVKLLITKCRDFFTERILVPSSHDTLLHLVSLGLNTAVDPAG
VDDIDLYIDGADEVSGKLDLVKGRGGAFLREKSLAVRSRVRMYVVDYTKYTGLNHIYVKPIPIEVVPVSVKYVIRKLQEL
GYGEPLLRMGTGKDGPVVSDNGNFIVDYRLLKPVEDPLSLHNTLKLVHGVIETGIFPSNLVDIVVVGEPAGVRVLGKNTG
GRE
>Mature_243_residues
MDASSIIEQAKLNACDYACRHLYEKYGDALVVGVGTGSTVKLLITKCRDFFTERILVPSSHDTLLHLVSLGLNTAVDPAG
VDDIDLYIDGADEVSGKLDLVKGRGGAFLREKSLAVRSRVRMYVVDYTKYTGLNHIYVKPIPIEVVPVSVKYVIRKLQEL
GYGEPLLRMGTGKDGPVVSDNGNFIVDYRLLKPVEDPLSLHNTLKLVHGVIETGIFPSNLVDIVVVGEPAGVRVLGKNTG
GRE

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=191, Percent_Identity=34.5549738219895, Blast_Score=102, Evalue=3e-22,
Organism=Escherichia coli, GI1789280, Length=208, Percent_Identity=34.1346153846154, Blast_Score=109, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17551758, Length=217, Percent_Identity=35.4838709677419, Blast_Score=114, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6324669, Length=211, Percent_Identity=31.2796208530806, Blast_Score=94, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281364072, Length=197, Percent_Identity=35.5329949238579, Blast_Score=108, Evalue=2e-24,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF00455 DeoR; PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 26478; Mature: 26478

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDASSIIEQAKLNACDYACRHLYEKYGDALVVGVGTGSTVKLLITKCRDFFTERILVPSS
CCHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHEEECCCC
HDTLLHLVSLGLNTAVDPAGVDDIDLYIDGADEVSGKLDLVKGRGGAFLREKSLAVRSRV
CHHHHHHHHHCCCCCCCCCCCCEEEEEEECCHHCCCCEEEEECCCCCEEHHHHHHHHHHE
RMYVVDYTKYTGLNHIYVKPIPIEVVPVSVKYVIRKLQELGYGEPLLRMGTGKDGPVVSD
EEEEEEEHHHCCCCEEEEECCCEEEEEHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEC
NGNFIVDYRLLKPVEDPLSLHNTLKLVHGVIETGIFPSNLVDIVVVGEPAGVRVLGKNTG
CCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEECCCC
GRE
CCC
>Mature Secondary Structure
MDASSIIEQAKLNACDYACRHLYEKYGDALVVGVGTGSTVKLLITKCRDFFTERILVPSS
CCHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHEEECCCC
HDTLLHLVSLGLNTAVDPAGVDDIDLYIDGADEVSGKLDLVKGRGGAFLREKSLAVRSRV
CHHHHHHHHHCCCCCCCCCCCCEEEEEEECCHHCCCCEEEEECCCCCEEHHHHHHHHHHE
RMYVVDYTKYTGLNHIYVKPIPIEVVPVSVKYVIRKLQELGYGEPLLRMGTGKDGPVVSD
EEEEEEEHHHCCCCEEEEECCCEEEEEHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEC
NGNFIVDYRLLKPVEDPLSLHNTLKLVHGVIETGIFPSNLVDIVVVGEPAGVRVLGKNTG
CCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEECCCC
GRE
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]