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The map label for this gene is glmM [H]

Identifier: 218883326

GI number: 218883326

Start: 9687

End: 11063

Strand: Reverse

Name: glmM [H]

Synonym: DKAM_0012

Alternate gene names: 218883326

Gene position: 11063-9687 (Counterclockwise)

Preceding gene: 218883327

Following gene: 218883325

Centisome position: 0.81

GC content: 43.43

Gene sequence:

>1377_bases
ATGAGCGATCCCCGGAGACTTTTCGGAACCGATGGAGTCAGAGGGGTTGTAAACGAAGACTTAAACCCGGAATTTATACT
GAGACTCGGGCTAGCAATAGGCTCCTATTTTGATAAAGGCTCCAGGGTACTTATTGGGATGGATTCAAGGGCTGGGGGCG
AGATAATTAAGGGCATTGTTTCAGCAGCACTAATGTCAACAGGTGTAAAGGTATATGATGCTGGATTCACCCCCACACCA
GCCCTTCAATACGTTGTCAAATCTAATGGCTTTGATGGAGGAGTTATGATTACAGCCAGCCATAACCCTCCCGAATATAA
CGGGATAAAGGTGATCGGCCCCTACGGAATCGAGATCAATAGGGATGAAGAAAGAAAGATAGAAGAGATATATTGGGAAA
GCAATTTCAGGAGGGTTAACTGGAGTAGTCTACCGTATAGTGTAGAGAAACATAAGATGGTTAACGAGGAATACGTGAAA
GCTGTGTTAAGCCATATAGATAAGGACCTTATTAGAGCCAAGAACTATAGGGTACTCATAGATCCAGCTAATAGTGTTGG
CGCATTAACAACGCCGCTAATAGTTAAGGAACTAGGTGCAAAACCAATTGTAATTAATGGAACACTAGATCCCTTATTCC
CTGGGAGAAACCCTGAGCCAACAGTTGAAAACCTGGCTGAAACAGCGAAGGTAACAAGGGAGTTAGGAGTCGCATTAGGT
ATCGCACATGACGCTGATGCCGATAGAGCTATAATAATAGATGAAAAAGGCGTTGTCAACTGGGGAGATCGAACAGCAAC
GCTTCTAGCTAAATATCTGAAAGAGGAGAAGGGATTAAGTGGGAAGGTCTATACTGCTGTATCATCCAGCATAATGGTGG
AGGAGGTTTTGAAACCCCTCAACATAGAGGTTGCCTGGCTTAAAGTGGGTAGTGTCGATATAGCTCACACCATGAGAAGG
AATGGTGATGCCTTATGTGGATTCGAGGAGAACGGTGGATTCATGTATCCACCCCACCAATATGTACGTGATGGAGGAAT
GACCACTGCATTATTTCTCGAGATGATGGCCAGGTACAATGCATCAGCATCACAATTATTCGATAAGCTACCAAAGTATT
ATACCTTGAAAAAGAAGTATAAGATGGATCGTGAGAAGGCTTTAAGAGTGGTTGAACTAGTTAAAGAAGCGTTTAAGGAT
AAACGGTTAATAACGATCGATGGTGTAAAAGTCATCTCATCCAATTACTGGTTTCTAGTGCGGCCAAGCGGTACGGAACC
CTTGCTCCGAGTAATGATCGAGGCTAAGGATGTTGAACGATTGAATGAGATATCATCATCGATTGATTCGATAATAAGGG
AGGTGGTAGGTAAGTGA

Upstream 100 bases:

>100_bases
AATGGGCTGAGTCGAGAAATCTCATAACTATCTTTGAGTTAAGAGAGGGTAGTGCCGAGTTATTATCTCTCGTAGAGGAA
TATATGGAGGGGTTAAATGA

Downstream 100 bases:

>100_bases
TGAGATATTGGGGGCTAGATGTCCTAGTATGCGTGCACTGTAAACATCACCCATTAGAGATTACAGTAATAGAATCCGAA
ACCCAAGAGATAAACACAGA

Product: phosphomannomutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MSDPRRLFGTDGVRGVVNEDLNPEFILRLGLAIGSYFDKGSRVLIGMDSRAGGEIIKGIVSAALMSTGVKVYDAGFTPTP
ALQYVVKSNGFDGGVMITASHNPPEYNGIKVIGPYGIEINRDEERKIEEIYWESNFRRVNWSSLPYSVEKHKMVNEEYVK
AVLSHIDKDLIRAKNYRVLIDPANSVGALTTPLIVKELGAKPIVINGTLDPLFPGRNPEPTVENLAETAKVTRELGVALG
IAHDADADRAIIIDEKGVVNWGDRTATLLAKYLKEEKGLSGKVYTAVSSSIMVEEVLKPLNIEVAWLKVGSVDIAHTMRR
NGDALCGFEENGGFMYPPHQYVRDGGMTTALFLEMMARYNASASQLFDKLPKYYTLKKKYKMDREKALRVVELVKEAFKD
KRLITIDGVKVISSNYWFLVRPSGTEPLLRVMIEAKDVERLNEISSSIDSIIREVVGK

Sequences:

>Translated_458_residues
MSDPRRLFGTDGVRGVVNEDLNPEFILRLGLAIGSYFDKGSRVLIGMDSRAGGEIIKGIVSAALMSTGVKVYDAGFTPTP
ALQYVVKSNGFDGGVMITASHNPPEYNGIKVIGPYGIEINRDEERKIEEIYWESNFRRVNWSSLPYSVEKHKMVNEEYVK
AVLSHIDKDLIRAKNYRVLIDPANSVGALTTPLIVKELGAKPIVINGTLDPLFPGRNPEPTVENLAETAKVTRELGVALG
IAHDADADRAIIIDEKGVVNWGDRTATLLAKYLKEEKGLSGKVYTAVSSSIMVEEVLKPLNIEVAWLKVGSVDIAHTMRR
NGDALCGFEENGGFMYPPHQYVRDGGMTTALFLEMMARYNASASQLFDKLPKYYTLKKKYKMDREKALRVVELVKEAFKD
KRLITIDGVKVISSNYWFLVRPSGTEPLLRVMIEAKDVERLNEISSSIDSIIREVVGK
>Mature_457_residues
SDPRRLFGTDGVRGVVNEDLNPEFILRLGLAIGSYFDKGSRVLIGMDSRAGGEIIKGIVSAALMSTGVKVYDAGFTPTPA
LQYVVKSNGFDGGVMITASHNPPEYNGIKVIGPYGIEINRDEERKIEEIYWESNFRRVNWSSLPYSVEKHKMVNEEYVKA
VLSHIDKDLIRAKNYRVLIDPANSVGALTTPLIVKELGAKPIVINGTLDPLFPGRNPEPTVENLAETAKVTRELGVALGI
AHDADADRAIIIDEKGVVNWGDRTATLLAKYLKEEKGLSGKVYTAVSSSIMVEEVLKPLNIEVAWLKVGSVDIAHTMRRN
GDALCGFEENGGFMYPPHQYVRDGGMTTALFLEMMARYNASASQLFDKLPKYYTLKKKYKMDREKALRVVELVKEAFKDK
RLITIDGVKVISSNYWFLVRPSGTEPLLRVMIEAKDVERLNEISSSIDSIIREVVGK

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1789566, Length=468, Percent_Identity=28.4188034188034, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1788361, Length=457, Percent_Identity=25.164113785558, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1786904, Length=507, Percent_Identity=24.4575936883629, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71993870, Length=476, Percent_Identity=24.1596638655462, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.10 [H]

Molecular weight: Translated: 50877; Mature: 50746

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDPRRLFGTDGVRGVVNEDLNPEFILRLGLAIGSYFDKGSRVLIGMDSRAGGEIIKGIV
CCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHH
SAALMSTGVKVYDAGFTPTPALQYVVKSNGFDGGVMITASHNPPEYNGIKVIGPYGIEIN
HHHHHHCCCEEEECCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEECCCCEEC
RDEERKIEEIYWESNFRRVNWSSLPYSVEKHKMVNEEYVKAVLSHIDKDLIRAKNYRVLI
CCHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
DPANSVGALTTPLIVKELGAKPIVINGTLDPLFPGRNPEPTVENLAETAKVTRELGVALG
ECCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEE
IAHDADADRAIIIDEKGVVNWGDRTATLLAKYLKEEKGLSGKVYTAVSSSIMVEEVLKPL
ECCCCCCCCEEEEECCCCEECCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCC
NIEVAWLKVGSVDIAHTMRRNGDALCGFEENGGFMYPPHQYVRDGGMTTALFLEMMARYN
CEEEEEEEECCCHHHHHHHCCCCEEEEEECCCCEECCCHHHHHCCCCHHHHHHHHHHHCC
ASASQLFDKLPKYYTLKKKYKMDREKALRVVELVKEAFKDKRLITIDGVKVISSNYWFLV
CCHHHHHHHCCHHEEHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEECCEEEEECCEEEEE
RPSGTEPLLRVMIEAKDVERLNEISSSIDSIIREVVGK
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDPRRLFGTDGVRGVVNEDLNPEFILRLGLAIGSYFDKGSRVLIGMDSRAGGEIIKGIV
CCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHH
SAALMSTGVKVYDAGFTPTPALQYVVKSNGFDGGVMITASHNPPEYNGIKVIGPYGIEIN
HHHHHHCCCEEEECCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEECCCCEEC
RDEERKIEEIYWESNFRRVNWSSLPYSVEKHKMVNEEYVKAVLSHIDKDLIRAKNYRVLI
CCHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
DPANSVGALTTPLIVKELGAKPIVINGTLDPLFPGRNPEPTVENLAETAKVTRELGVALG
ECCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEE
IAHDADADRAIIIDEKGVVNWGDRTATLLAKYLKEEKGLSGKVYTAVSSSIMVEEVLKPL
ECCCCCCCCEEEEECCCCEECCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCC
NIEVAWLKVGSVDIAHTMRRNGDALCGFEENGGFMYPPHQYVRDGGMTTALFLEMMARYN
CEEEEEEEECCCHHHHHHHCCCCEEEEEECCCCEECCCHHHHHCCCCHHHHHHHHHHHCC
ASASQLFDKLPKYYTLKKKYKMDREKALRVVELVKEAFKDKRLITIDGVKVISSNYWFLV
CCHHHHHHHCCHHEEHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEECCEEEEECCEEEEE
RPSGTEPLLRVMIEAKDVERLNEISSSIDSIIREVVGK
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA