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The map label for this gene is yqhT [H]

Identifier: 218710978

GI number: 218710978

Start: 3236327

End: 3238117

Strand: Direct

Name: yqhT [H]

Synonym: VS_3092

Alternate gene names: 218710978

Gene position: 3236327-3238117 (Clockwise)

Preceding gene: 218710977

Following gene: 218710987

Centisome position: 98.09

GC content: 48.19

Gene sequence:

>1791_bases
ATGCACAATATCACTGCTGAACGCGTTGCTGCGGTTCGAGCTTGGCTTGAAACAAGCAACCTAGATGCCGTTATCATTCC
ACACGAAGACGAATATCTAGGTGAATACGTTCCCGCTCATAACGAGCGACTTCACTGGTTAACAGGTTTCACTGGCTCTG
CAGGTGCCGCTGTTATCACTCGTGAAACTGCTGCTATTTTTGTAGATGGTCGCTACACCGTTCAGGTTCGTAAGCAGGTA
CCAGCAGAGTTATTTGAGTATCGCCACCTTATTGAAGAACCGGCTTTAGATTGGATCATCAATTCATTGCCGCAAGGCAG
TAAGGTTGCATTCGACCCACGCATGCACACCGCTGCTTGGTTGAAAGGCGCACAAGCAAAACTAGCGGAGAAAGTTGAAC
TAACGACACTCTCTTCTAATCCAATTGATGAGCTTTGGTCTGACCGTCCTGAGCCTGTTGTATCTGATGTTCGCCTAATG
GCAACAGATGCCGTTGGTCAATCAAGTGAAAGCAAACGTGCGGAGATTGCTGGCTTACTAAAAGCAAAAGGTGCGGACGC
CGCTATCCTTACCGAGCTAGACTCAATCTGTTGGTTGCTTAACATTCGTGGCTTGGACGTATCTCGCCTACCTGTTGTGT
TATCCAACGCGATCATTCACGCCGATGAAAGCGTCGATTTCTTCCTAGACCCAGCACGCATCCCGGCTGGCTTTGAAGCG
CACGTTGGTAATGGTATTCGCGTTTCTCACCCATCAGAGCTTGAAGCGCGCCTTCAATCTTTAGAAAGCAAAAACGTATC
TGTCGATTCAGGCACAAGTAATGCTTGGTATACGCTTGTTCTTCAAAACGCTGGCGCTCATCTCATTGAAGCAGCAGACC
CATGTCTAATGCCAAAAGCCGCTAAAAACGATACTGAAATTGCCGGCATGAAGGCGTGTCACATTCGTGATGGTGTTGCG
ATGGCGAAATTCCTATCTTGGATTGATGCAGAAGTCGCGCAAGGTAACCTACACAACGAAGCGGTATTGGCTGACAAAGT
ACAATCATTCCGCGAGCAAGACCCGACGCTGATGGATCTAAGTTTTGACACCATTTCTGCGGCTGGCGGCAACGCAGCAA
TGTGTCACTACAACCATGAGAACCAACCTGAACCTGGTCAGCTAGAACTGAATACTCTGTACCTAGTCGATTCAGGCGGT
CAGTACTTAGATGGTACAACCGACATCACTCGTACTATCGCGATTGGCCAACCAAGCGACGAAATGATTCAGCAGTTCAC
ATTAGCGCTTAAAGGTCACATCGGCATTGCACGTGCGCGTTTCCCACAGGGTACTCGTGGTTTCCAACTGGATATCCTAG
CGCGTCAGCACTTATGGGCAGAAGGCTTCGATTACGATCATGGTACTGGTCACGGTGTTGGTCACTTCCTAAGTGTTCAT
GAAGGCCCACAAAGCATCTCTAAGAAGCTTATCGACGTACCTCTTGTTGAAGGCATGGTGTTATCAAACGAGCCGGGTTA
CTACCGTGCTGATGAGTTTGGTATCCGTATCGAGAACCTAGAATTGGTAGTTGAGCTTCCAACTCAAGGTGATTTCTCAG
TACTAACGTTTGAGTCGCTAACTCGTTGCCCTATCGATAAGCGCAACATCAATGTTGATTTGCTAACACGACCTGAACTG
GCGTGGCTGAACGACTACCATCAGAAGGTATGGAACGACGTTAGCCCATTAGTTGAAGGTGATACATTGGAATGGTTACG
CCAATCGACAACTCCATTGGCTCACGCTTAA

Upstream 100 bases:

>100_bases
CAAACGAACAAAAGCGCTAGCTTATTGACCTAATAAGTCCCCTCGCATGTATATCGACTGTGAGTGTTAACAAGGACCCT
AACAATAAGGATAAACACAG

Downstream 100 bases:

>100_bases
TGCTTCGCTAAGCGCTTAACTGAACCAACAAACTTGCTCGGTTAATAAGTTAAATAGCAAATAGCAAAACGGCTACCCAA
GGGTAGCCGTTTTTATTTGC

Product: aminopeptidase P

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 596; Mature: 596

Protein sequence:

>596_residues
MHNITAERVAAVRAWLETSNLDAVIIPHEDEYLGEYVPAHNERLHWLTGFTGSAGAAVITRETAAIFVDGRYTVQVRKQV
PAELFEYRHLIEEPALDWIINSLPQGSKVAFDPRMHTAAWLKGAQAKLAEKVELTTLSSNPIDELWSDRPEPVVSDVRLM
ATDAVGQSSESKRAEIAGLLKAKGADAAILTELDSICWLLNIRGLDVSRLPVVLSNAIIHADESVDFFLDPARIPAGFEA
HVGNGIRVSHPSELEARLQSLESKNVSVDSGTSNAWYTLVLQNAGAHLIEAADPCLMPKAAKNDTEIAGMKACHIRDGVA
MAKFLSWIDAEVAQGNLHNEAVLADKVQSFREQDPTLMDLSFDTISAAGGNAAMCHYNHENQPEPGQLELNTLYLVDSGG
QYLDGTTDITRTIAIGQPSDEMIQQFTLALKGHIGIARARFPQGTRGFQLDILARQHLWAEGFDYDHGTGHGVGHFLSVH
EGPQSISKKLIDVPLVEGMVLSNEPGYYRADEFGIRIENLELVVELPTQGDFSVLTFESLTRCPIDKRNINVDLLTRPEL
AWLNDYHQKVWNDVSPLVEGDTLEWLRQSTTPLAHA

Sequences:

>Translated_596_residues
MHNITAERVAAVRAWLETSNLDAVIIPHEDEYLGEYVPAHNERLHWLTGFTGSAGAAVITRETAAIFVDGRYTVQVRKQV
PAELFEYRHLIEEPALDWIINSLPQGSKVAFDPRMHTAAWLKGAQAKLAEKVELTTLSSNPIDELWSDRPEPVVSDVRLM
ATDAVGQSSESKRAEIAGLLKAKGADAAILTELDSICWLLNIRGLDVSRLPVVLSNAIIHADESVDFFLDPARIPAGFEA
HVGNGIRVSHPSELEARLQSLESKNVSVDSGTSNAWYTLVLQNAGAHLIEAADPCLMPKAAKNDTEIAGMKACHIRDGVA
MAKFLSWIDAEVAQGNLHNEAVLADKVQSFREQDPTLMDLSFDTISAAGGNAAMCHYNHENQPEPGQLELNTLYLVDSGG
QYLDGTTDITRTIAIGQPSDEMIQQFTLALKGHIGIARARFPQGTRGFQLDILARQHLWAEGFDYDHGTGHGVGHFLSVH
EGPQSISKKLIDVPLVEGMVLSNEPGYYRADEFGIRIENLELVVELPTQGDFSVLTFESLTRCPIDKRNINVDLLTRPEL
AWLNDYHQKVWNDVSPLVEGDTLEWLRQSTTPLAHA
>Mature_596_residues
MHNITAERVAAVRAWLETSNLDAVIIPHEDEYLGEYVPAHNERLHWLTGFTGSAGAAVITRETAAIFVDGRYTVQVRKQV
PAELFEYRHLIEEPALDWIINSLPQGSKVAFDPRMHTAAWLKGAQAKLAEKVELTTLSSNPIDELWSDRPEPVVSDVRLM
ATDAVGQSSESKRAEIAGLLKAKGADAAILTELDSICWLLNIRGLDVSRLPVVLSNAIIHADESVDFFLDPARIPAGFEA
HVGNGIRVSHPSELEARLQSLESKNVSVDSGTSNAWYTLVLQNAGAHLIEAADPCLMPKAAKNDTEIAGMKACHIRDGVA
MAKFLSWIDAEVAQGNLHNEAVLADKVQSFREQDPTLMDLSFDTISAAGGNAAMCHYNHENQPEPGQLELNTLYLVDSGG
QYLDGTTDITRTIAIGQPSDEMIQQFTLALKGHIGIARARFPQGTRGFQLDILARQHLWAEGFDYDHGTGHGVGHFLSVH
EGPQSISKKLIDVPLVEGMVLSNEPGYYRADEFGIRIENLELVVELPTQGDFSVLTFESLTRCPIDKRNINVDLLTRPEL
AWLNDYHQKVWNDVSPLVEGDTLEWLRQSTTPLAHA

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI264681563, Length=624, Percent_Identity=37.8205128205128, Blast_Score=379, Evalue=1e-105,
Organism=Homo sapiens, GI93141226, Length=605, Percent_Identity=34.3801652892562, Blast_Score=355, Evalue=6e-98,
Organism=Homo sapiens, GI264681565, Length=623, Percent_Identity=36.115569823435, Blast_Score=352, Evalue=7e-97,
Organism=Escherichia coli, GI1788728, Length=358, Percent_Identity=24.0223463687151, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17509539, Length=611, Percent_Identity=34.5335515548282, Blast_Score=343, Evalue=1e-94,
Organism=Caenorhabditis elegans, GI25149105, Length=612, Percent_Identity=30.5555555555556, Blast_Score=271, Evalue=9e-73,
Organism=Saccharomyces cerevisiae, GI6322999, Length=654, Percent_Identity=31.9571865443425, Blast_Score=319, Evalue=7e-88,
Organism=Drosophila melanogaster, GI17137632, Length=611, Percent_Identity=37.6432078559738, Blast_Score=362, Evalue=1e-100,
Organism=Drosophila melanogaster, GI161078230, Length=597, Percent_Identity=30.1507537688442, Blast_Score=261, Evalue=8e-70,
Organism=Drosophila melanogaster, GI21357287, Length=597, Percent_Identity=30.1507537688442, Blast_Score=261, Evalue=8e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 65628; Mature: 65628

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHNITAERVAAVRAWLETSNLDAVIIPHEDEYLGEYVPAHNERLHWLTGFTGSAGAAVIT
CCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHCCCCCCCCEEEEEECCCCCCCCEEEE
RETAAIFVDGRYTVQVRKQVPAELFEYRHLIEEPALDWIINSLPQGSKVAFDPRMHTAAW
ECEEEEEECCEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHH
LKGAQAKLAEKVELTTLSSNPIDELWSDRPEPVVSDVRLMATDAVGQSSESKRAEIAGLL
HCCHHHHHHHEEEEEEECCCCHHHHHCCCCCCHHHHHHEEEECCCCCCCCHHHHHHHHHH
KAKGADAAILTELDSICWLLNIRGLDVSRLPVVLSNAIIHADESVDFFLDPARIPAGFEA
HCCCCCHHHHHHHHHHEEEEEECCCCHHHHHHHHHCEEEECCCCCEEEECCCCCCCCCEE
HVGNGIRVSHPSELEARLQSLESKNVSVDSGTSNAWYTLVLQNAGAHLIEAADPCLMPKA
ECCCCEEECCCHHHHHHHHHHHCCCCEECCCCCCCEEEEEEECCCCCEEECCCCCCCCCC
AKNDTEIAGMKACHIRDGVAMAKFLSWIDAEVAQGNLHNEAVLADKVQSFREQDPTLMDL
CCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEE
SFDTISAAGGNAAMCHYNHENQPEPGQLELNTLYLVDSGGQYLDGTTDITRTIAIGQPSD
ECHHEECCCCCEEEEEECCCCCCCCCEEEEEEEEEEECCCCCCCCCCCEEEEEEECCCHH
EMIQQFTLALKGHIGIARARFPQGTRGFQLDILARQHLWAEGFDYDHGTGHGVGHFLSVH
HHHHHHHHHHHCCCEEEECCCCCCCCCEEEEEEEHHHHHHCCCCCCCCCCCCCHHEEEEC
EGPQSISKKLIDVPLVEGMVLSNEPGYYRADEFGIRIENLELVVELPTQGDFSVLTFESL
CCHHHHHHHHHCCHHHCCEEEECCCCCEECHHHCEEEECEEEEEECCCCCCEEEEEHHHH
TRCPIDKRNINVDLLTRPELAWLNDYHQKVWNDVSPLVEGDTLEWLRQSTTPLAHA
HCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCC
>Mature Secondary Structure
MHNITAERVAAVRAWLETSNLDAVIIPHEDEYLGEYVPAHNERLHWLTGFTGSAGAAVIT
CCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHCCCCCCCCEEEEEECCCCCCCCEEEE
RETAAIFVDGRYTVQVRKQVPAELFEYRHLIEEPALDWIINSLPQGSKVAFDPRMHTAAW
ECEEEEEECCEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHH
LKGAQAKLAEKVELTTLSSNPIDELWSDRPEPVVSDVRLMATDAVGQSSESKRAEIAGLL
HCCHHHHHHHEEEEEEECCCCHHHHHCCCCCCHHHHHHEEEECCCCCCCCHHHHHHHHHH
KAKGADAAILTELDSICWLLNIRGLDVSRLPVVLSNAIIHADESVDFFLDPARIPAGFEA
HCCCCCHHHHHHHHHHEEEEEECCCCHHHHHHHHHCEEEECCCCCEEEECCCCCCCCCEE
HVGNGIRVSHPSELEARLQSLESKNVSVDSGTSNAWYTLVLQNAGAHLIEAADPCLMPKA
ECCCCEEECCCHHHHHHHHHHHCCCCEECCCCCCCEEEEEEECCCCCEEECCCCCCCCCC
AKNDTEIAGMKACHIRDGVAMAKFLSWIDAEVAQGNLHNEAVLADKVQSFREQDPTLMDL
CCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEE
SFDTISAAGGNAAMCHYNHENQPEPGQLELNTLYLVDSGGQYLDGTTDITRTIAIGQPSD
ECHHEECCCCCEEEEEECCCCCCCCCEEEEEEEEEEECCCCCCCCCCCEEEEEEECCCHH
EMIQQFTLALKGHIGIARARFPQGTRGFQLDILARQHLWAEGFDYDHGTGHGVGHFLSVH
HHHHHHHHHHHCCCEEEECCCCCCCCCEEEEEEEHHHHHHCCCCCCCCCCCCCHHEEEEC
EGPQSISKKLIDVPLVEGMVLSNEPGYYRADEFGIRIENLELVVELPTQGDFSVLTFESL
CCHHHHHHHHHCCHHHCCEEEECCCCCEECHHHCEEEECEEEEEECCCCCCEEEEEHHHH
TRCPIDKRNINVDLLTRPELAWLNDYHQKVWNDVSPLVEGDTLEWLRQSTTPLAHA
HCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]