| Definition | Vibrio splendidus LGP32 chromosome 1, complete genome. |
|---|---|
| Accession | NC_011753 |
| Length | 3,299,303 |
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The map label for this gene is mrcA [H]
Identifier: 218710795
GI number: 218710795
Start: 3025531
End: 3028089
Strand: Direct
Name: mrcA [H]
Synonym: VS_2878
Alternate gene names: 218710795
Gene position: 3025531-3028089 (Clockwise)
Preceding gene: 218710782
Following gene: 218710797
Centisome position: 91.7
GC content: 47.13
Gene sequence:
>2559_bases GTGAAGTTCATAAAGCGATTATTCATATTTACATTGATTTGCATGATTCTTGGAGTCAGTACAATTTTCGGGTTTTACTA TTACGTAAAACCAGAGTTGCCTGATGTTGCCACTTTGCGTGACGTAGAACTCCAAACGCCAATGCAAGTCTTCAGTCAAG ACGGTAAATTGATCTCTCAATTTGGTGAAAAGCGTCGTAATCCAGTGACTTATGACGAGATTCCTCGCCACCTAGTTGAA GCTTTGATTGCTACCGAAGATAGCCGCTTTTACGAGCACCCTGGTATTGATCCAATTGGTATCACTCGAGCAGCACTCGT GGTTGCTATGTCCGGTTCAGCCAAACAAGGGGCAAGTACCATTACTCAGCAGCTTGCGCGTAACTTCTTCTTATCTAATG AGAAAAAGATCATGCGTAAAATCAAAGAGATCTTCATTGCGATCCACATTGAGCAACTTCTTAGTAAAGAAGAGATCATG GAGCTGTACGTAAACAAGATCTTCCTTGGTCACCGTTCATACGGTTTCGGCGCAGCAGCGCGTGTTTATTTTGGAAAGGA TCTTCCTGAACTCACCTTAAGTGAATTGGCTACGCTTGCGGGCATGCCAAAAGCACCTTCAACTATGAACCCTATTTATT CTGTTGAGCGTGCGACCAACCGTCGCAACGTGGTATTACGTCGTATGCTAGACGAAAAATACATCACTCAATCAGAGTAC GATGAAGCTCGCAGTGAAGAACTTATCTCGAAATATCACGGTGCCGAGATTGAACTGAGCGCGCCATATGTAGCAGAAGT AGCACGAGCTTGGATGGTTGAACGCTATGGTGAAGCCGCTTACACATCCGGCATGAAGGTTTACACGACCGTTGATTCAA AACTGCAAAAAGCAGCGAACCAAGCCGCGATTAAGAACCTACTTGGCTACGATGAACGTCACGGTTACCGTGGTGCTGAA AAAGTATTGTGGCAAACGGCGCAGTCGGCTTGGGATCAAAAACAAATCGTTAAGCACCTTAAGTCTCAACCAACCTATGG TGACTTAGTACCAGCAGTTGTAACCGCTGTTGATTCGAAAAGCGCTCAAGTTTGGGTTAAGAACCAAGGCGAAGGCACTA TCGAGTGGCAAGGCATGAACTGGGCGCGTAAATTCCTAACGGACAACCGCCAAGGTCCAGCGCCTTCTCAAGCTAAAGAG ATTTTGGCTGTTGGTGAGCAAGTTTGGGTTCGCCATGAAGCAGTAACCGGCGATGAAGTATCTGAAGAGCCTACCGAAGA AACAACAACTGAACCTGAAACACCGGTTGTATGGCGACTAAGCCAAGTGCCAAATGCAAACACCGCGTTTGTTGCCATGA ACCCTAACAACGGCGCAGTATTGTCGATGGTGGGTGGCTTTAACTTTGTACACAACAAATTCAACCGTGCGACCCAATCT ATTCGTCAGGTGGGTTCTGGTATCAAACCATTTATCTACTCAGCAGCGATTGAAAAAGGCTTAACGCTAGCCTCACTGAT CAACGATGCGCCTATCAATCAATGGGATAAGAGCCAAGGTACGGCATGGCGACCAAAGAACTCACCACCGACCTATGTGG GTCCAACTCGTTTACGTATTGGCTTAGCTCAATCTAAAAACGTAATGGCGGTACGTGTACTGCGCGAAGTGGGCTTGGAT GATACTCGTAACTACCTAACTCGATTTGGTTTTGATATTGACGAAGTACCGCGTTCTGAAACCATTGCTCTGGGTGCGGG TAGCTTAACGCCAATGAAGGTAGCACAAGGTTACTCAGTATTTGCGAATGGCGGCTACTACGTTGAACCTTTCTACATCA GCCGTATTGAGACACCATTTGGTGAGACTGAATTCCAAGCGACACCGAAAGTTGTGTGTAAAGACGATTGCCAACAGCCA ATGACCTCAGATTCAATGGCTAATGAGTTTGCAGAGCAAGATGTGGATGCCCAAGTACAGTACGCACCTCAAGTGATCAC TGAGCAGAACGCGTTCCTTGTTCGTGAAATGATGTACAGCAACATCTGGGGCGGCGGTGACTGGAGTGCAGGCACTGGCT GGAATGGTACAGGTTGGCGTGCTCAACCGCTGAAGCGTCGCGATATTGGCGGAAAAACCGGTACCACCAACGATTCGAAA GATACTTGGTACAGCGGTTACGGCCCTGGCATGGTTGCAACGGTATGGGTTGGCTTTGACAACCACAACCGTAACCTAGG TCGAACCAAAGCGAACTCTAACCTTGGTAAGAATCAAATTACAGGTGCAGAAGCGGGCGCTAAAACAGCAGAGCCGGCAT GGGTTGATTTCATGGGCACAGCGTTAGCGGGTGTTCCTGCACAGCGTAAAGAGCTTCCAGAAAATATCGTTCGCGTTCGT ATCGACCGTGAAACTGGCTTACTGACCAACAAGTTCGATAGCTCATCAATGTTCGAGTATTTCGAGAAAGGCACTGAGCC AACCGAGTACATTACTGAACGTTTCAATGATGACATCTACTCAACGTCATCAGGCGAAGCAGTAGAAGAGCTGTTCTAA
Upstream 100 bases:
>100_bases GATTATTAGTTAAATAAGCGTTAATAAACGAAAGCTAAGTTTTTAACCTAGAGTACAAGGGTTTGCTGCTTATCAGCCTT AACTAATCAGGGATTATCCG
Downstream 100 bases:
>100_bases TTAGGGTTTGTTGAACCAAGTAACATGAACCAACAAAAAGGGTTGATATGAATTCATATCAACCCTTTTTTTATGTCTCT AACCTGATCTATCTACGATT
Product: penicillin-binding protein 1A
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 852; Mature: 852
Protein sequence:
>852_residues MKFIKRLFIFTLICMILGVSTIFGFYYYVKPELPDVATLRDVELQTPMQVFSQDGKLISQFGEKRRNPVTYDEIPRHLVE ALIATEDSRFYEHPGIDPIGITRAALVVAMSGSAKQGASTITQQLARNFFLSNEKKIMRKIKEIFIAIHIEQLLSKEEIM ELYVNKIFLGHRSYGFGAAARVYFGKDLPELTLSELATLAGMPKAPSTMNPIYSVERATNRRNVVLRRMLDEKYITQSEY DEARSEELISKYHGAEIELSAPYVAEVARAWMVERYGEAAYTSGMKVYTTVDSKLQKAANQAAIKNLLGYDERHGYRGAE KVLWQTAQSAWDQKQIVKHLKSQPTYGDLVPAVVTAVDSKSAQVWVKNQGEGTIEWQGMNWARKFLTDNRQGPAPSQAKE ILAVGEQVWVRHEAVTGDEVSEEPTEETTTEPETPVVWRLSQVPNANTAFVAMNPNNGAVLSMVGGFNFVHNKFNRATQS IRQVGSGIKPFIYSAAIEKGLTLASLINDAPINQWDKSQGTAWRPKNSPPTYVGPTRLRIGLAQSKNVMAVRVLREVGLD DTRNYLTRFGFDIDEVPRSETIALGAGSLTPMKVAQGYSVFANGGYYVEPFYISRIETPFGETEFQATPKVVCKDDCQQP MTSDSMANEFAEQDVDAQVQYAPQVITEQNAFLVREMMYSNIWGGGDWSAGTGWNGTGWRAQPLKRRDIGGKTGTTNDSK DTWYSGYGPGMVATVWVGFDNHNRNLGRTKANSNLGKNQITGAEAGAKTAEPAWVDFMGTALAGVPAQRKELPENIVRVR IDRETGLLTNKFDSSSMFEYFEKGTEPTEYITERFNDDIYSTSSGEAVEELF
Sequences:
>Translated_852_residues MKFIKRLFIFTLICMILGVSTIFGFYYYVKPELPDVATLRDVELQTPMQVFSQDGKLISQFGEKRRNPVTYDEIPRHLVE ALIATEDSRFYEHPGIDPIGITRAALVVAMSGSAKQGASTITQQLARNFFLSNEKKIMRKIKEIFIAIHIEQLLSKEEIM ELYVNKIFLGHRSYGFGAAARVYFGKDLPELTLSELATLAGMPKAPSTMNPIYSVERATNRRNVVLRRMLDEKYITQSEY DEARSEELISKYHGAEIELSAPYVAEVARAWMVERYGEAAYTSGMKVYTTVDSKLQKAANQAAIKNLLGYDERHGYRGAE KVLWQTAQSAWDQKQIVKHLKSQPTYGDLVPAVVTAVDSKSAQVWVKNQGEGTIEWQGMNWARKFLTDNRQGPAPSQAKE ILAVGEQVWVRHEAVTGDEVSEEPTEETTTEPETPVVWRLSQVPNANTAFVAMNPNNGAVLSMVGGFNFVHNKFNRATQS IRQVGSGIKPFIYSAAIEKGLTLASLINDAPINQWDKSQGTAWRPKNSPPTYVGPTRLRIGLAQSKNVMAVRVLREVGLD DTRNYLTRFGFDIDEVPRSETIALGAGSLTPMKVAQGYSVFANGGYYVEPFYISRIETPFGETEFQATPKVVCKDDCQQP MTSDSMANEFAEQDVDAQVQYAPQVITEQNAFLVREMMYSNIWGGGDWSAGTGWNGTGWRAQPLKRRDIGGKTGTTNDSK DTWYSGYGPGMVATVWVGFDNHNRNLGRTKANSNLGKNQITGAEAGAKTAEPAWVDFMGTALAGVPAQRKELPENIVRVR IDRETGLLTNKFDSSSMFEYFEKGTEPTEYITERFNDDIYSTSSGEAVEELF >Mature_852_residues MKFIKRLFIFTLICMILGVSTIFGFYYYVKPELPDVATLRDVELQTPMQVFSQDGKLISQFGEKRRNPVTYDEIPRHLVE ALIATEDSRFYEHPGIDPIGITRAALVVAMSGSAKQGASTITQQLARNFFLSNEKKIMRKIKEIFIAIHIEQLLSKEEIM ELYVNKIFLGHRSYGFGAAARVYFGKDLPELTLSELATLAGMPKAPSTMNPIYSVERATNRRNVVLRRMLDEKYITQSEY DEARSEELISKYHGAEIELSAPYVAEVARAWMVERYGEAAYTSGMKVYTTVDSKLQKAANQAAIKNLLGYDERHGYRGAE KVLWQTAQSAWDQKQIVKHLKSQPTYGDLVPAVVTAVDSKSAQVWVKNQGEGTIEWQGMNWARKFLTDNRQGPAPSQAKE ILAVGEQVWVRHEAVTGDEVSEEPTEETTTEPETPVVWRLSQVPNANTAFVAMNPNNGAVLSMVGGFNFVHNKFNRATQS IRQVGSGIKPFIYSAAIEKGLTLASLINDAPINQWDKSQGTAWRPKNSPPTYVGPTRLRIGLAQSKNVMAVRVLREVGLD DTRNYLTRFGFDIDEVPRSETIALGAGSLTPMKVAQGYSVFANGGYYVEPFYISRIETPFGETEFQATPKVVCKDDCQQP MTSDSMANEFAEQDVDAQVQYAPQVITEQNAFLVREMMYSNIWGGGDWSAGTGWNGTGWRAQPLKRRDIGGKTGTTNDSK DTWYSGYGPGMVATVWVGFDNHNRNLGRTKANSNLGKNQITGAEAGAKTAEPAWVDFMGTALAGVPAQRKELPENIVRVR IDRETGLLTNKFDSSSMFEYFEKGTEPTEYITERFNDDIYSTSSGEAVEELF
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG5009
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=884, Percent_Identity=51.5837104072398, Blast_Score=920, Evalue=0.0, Organism=Escherichia coli, GI1786343, Length=281, Percent_Identity=36.6548042704626, Blast_Score=145, Evalue=1e-35, Organism=Escherichia coli, GI1788867, Length=257, Percent_Identity=33.852140077821, Blast_Score=129, Evalue=1e-30, Organism=Escherichia coli, GI1789601, Length=176, Percent_Identity=33.5227272727273, Blast_Score=83, Evalue=8e-17,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.-
Molecular weight: Translated: 95159; Mature: 95159
Theoretical pI: Translated: 5.95; Mature: 5.95
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKFIKRLFIFTLICMILGVSTIFGFYYYVKPELPDVATLRDVELQTPMQVFSQDGKLISQ CHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHCCCCHHCHHHHHHCCCHHHHH FGEKRRNPVTYDEIPRHLVEALIATEDSRFYEHPGIDPIGITRAALVVAMSGSAKQGAST HHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHEEECCCCCCHHHH ITQQLARNFFLSNEKKIMRKIKEIFIAIHIEQLLSKEEIMELYVNKIFLGHRSYGFGAAA HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCHHE RVYFGKDLPELTLSELATLAGMPKAPSTMNPIYSVERATNRRNVVLRRMLDEKYITQSEY EEEECCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCHHHH DEARSEELISKYHGAEIELSAPYVAEVARAWMVERYGEAAYTSGMKVYTTVDSKLQKAAN HHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCCHHHHCCCEEEEEHHHHHHHHHH QAAIKNLLGYDERHGYRGAEKVLWQTAQSAWDQKQIVKHLKSQPTYGDLVPAVVTAVDSK HHHHHHHHCCCHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHCCC SAQVWVKNQGEGTIEWQGMNWARKFLTDNRQGPAPSQAKEILAVGEQVWVRHEAVTGDEV CCEEEEEECCCEEEEECCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC SEEPTEETTTEPETPVVWRLSQVPNANTAFVAMNPNNGAVLSMVGGFNFVHNKFNRATQS CCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHH IRQVGSGIKPFIYSAAIEKGLTLASLINDAPINQWDKSQGTAWRPKNSPPTYVGPTRLRI HHHHCCCCCHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEE GLAQSKNVMAVRVLREVGLDDTRNYLTRFGFDIDEVPRSETIALGAGSLTPMKVAQGYSV EECCCCCHHHHHHHHHHCCCHHHHHHHHHCCCHHHCCCCCEEEEECCCCCHHHHHCCCEE FANGGYYVEPFYISRIETPFGETEFQATPKVVCKDDCQQPMTSDSMANEFAEQDVDAQVQ EECCCEEECEEEEEEECCCCCCCCCCCCCCEEEHHHHCCCCCCHHHHHHHHHHCCCCHHH YAPQVITEQNAFLVREMMYSNIWGGGDWSAGTGWNGTGWRAQPLKRRDIGGKTGTTNDSK HCCHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCC DTWYSGYGPGMVATVWVGFDNHNRNLGRTKANSNLGKNQITGAEAGAKTAEPAWVDFMGT CCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH ALAGVPAQRKELPENIVRVRIDRETGLLTNKFDSSSMFEYFEKGTEPTEYITERFNDDIY HHHCCCHHHHHHHHHHEEEEECCCCCCEECCCCCHHHHHHHHCCCCHHHHHHHHHCCCCC STSSGEAVEELF CCCCCHHHHHHC >Mature Secondary Structure MKFIKRLFIFTLICMILGVSTIFGFYYYVKPELPDVATLRDVELQTPMQVFSQDGKLISQ CHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHCCCCHHCHHHHHHCCCHHHHH FGEKRRNPVTYDEIPRHLVEALIATEDSRFYEHPGIDPIGITRAALVVAMSGSAKQGAST HHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHEEECCCCCCHHHH ITQQLARNFFLSNEKKIMRKIKEIFIAIHIEQLLSKEEIMELYVNKIFLGHRSYGFGAAA HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCHHE RVYFGKDLPELTLSELATLAGMPKAPSTMNPIYSVERATNRRNVVLRRMLDEKYITQSEY EEEECCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCHHHH DEARSEELISKYHGAEIELSAPYVAEVARAWMVERYGEAAYTSGMKVYTTVDSKLQKAAN HHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCCHHHHCCCEEEEEHHHHHHHHHH QAAIKNLLGYDERHGYRGAEKVLWQTAQSAWDQKQIVKHLKSQPTYGDLVPAVVTAVDSK HHHHHHHHCCCHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHCCC SAQVWVKNQGEGTIEWQGMNWARKFLTDNRQGPAPSQAKEILAVGEQVWVRHEAVTGDEV CCEEEEEECCCEEEEECCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC SEEPTEETTTEPETPVVWRLSQVPNANTAFVAMNPNNGAVLSMVGGFNFVHNKFNRATQS CCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHH IRQVGSGIKPFIYSAAIEKGLTLASLINDAPINQWDKSQGTAWRPKNSPPTYVGPTRLRI HHHHCCCCCHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEE GLAQSKNVMAVRVLREVGLDDTRNYLTRFGFDIDEVPRSETIALGAGSLTPMKVAQGYSV EECCCCCHHHHHHHHHHCCCHHHHHHHHHCCCHHHCCCCCEEEEECCCCCHHHHHCCCEE FANGGYYVEPFYISRIETPFGETEFQATPKVVCKDDCQQPMTSDSMANEFAEQDVDAQVQ EECCCEEECEEEEEEECCCCCCCCCCCCCCEEEHHHHCCCCCCHHHHHHHHHHCCCCHHH YAPQVITEQNAFLVREMMYSNIWGGGDWSAGTGWNGTGWRAQPLKRRDIGGKTGTTNDSK HCCHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCC DTWYSGYGPGMVATVWVGFDNHNRNLGRTKANSNLGKNQITGAEAGAKTAEPAWVDFMGT CCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH ALAGVPAQRKELPENIVRVRIDRETGLLTNKFDSSSMFEYFEKGTEPTEYITERFNDDIY HHHCCCHHHHHHHHHHEEEEECCCCCCEECCCCCHHHHHHHHCCCCHHHHHHHHHCCCCC STSSGEAVEELF CCCCCHHHHHHC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 10952301 [H]