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The map label for this gene is kdsC [H]

Identifier: 218710673

GI number: 218710673

Start: 2918615

End: 2919172

Strand: Direct

Name: kdsC [H]

Synonym: VS_2753

Alternate gene names: 218710673

Gene position: 2918615-2919172 (Clockwise)

Preceding gene: 218710672

Following gene: 218710674

Centisome position: 88.46

GC content: 43.19

Gene sequence:

>558_bases
ATGTCACAAACAGTCGAAACTCTATACGGCACGGTAGATTCAGAAGTGTTTGCCGTAGCAAAAGAGATCAAATTGCTTAT
TTGCGATGTCGATGGCGTGTTCTCAGATGGTCGCATCTACATGGGTAACAATGGTGAAGAGCTAAAAACTTTCCATACGC
GCGACGGTTACGGCATTAAATCGTTGATGAACGCAGGCGTTGAAATCGCGATCATCACTGGCCGTAAATCTAAAATTGTT
GAAAATCGAATGACCGCTCTCGGTATTAAGCTAATTTATCAAGGTCAGGATGATAAAGTTAAAGCCTACCAAGATATTTG
CGATAAGCTTTCGATCAATCCTGAAAACACAGGTTATATCGGAGACGATTTAATCGATTGGCCTGTAATGGCAAAGGTTG
GCTTGAAGGTATGTGTGGCAGACGGCCACCCATTGCTTGCACAAAGAGCCAACTATGTAACCACCATTAATGGTGGTTAC
GGTGCTGTTCGTGAAGTCTGCGACCTTATTTTACAAGCAAGAAGCGAACTCGACGTGCACAAAGGTTTAAGCATATGA

Upstream 100 bases:

>100_bases
TGATGCAAGCTAAGAGCATCAATGGCTTGATGTTGTGTGATAGTGGCAAATTAGTAGGCGCTTTAAATATGCATGACTTA
CTGAAAGCAGGAGTAATGTA

Downstream 100 bases:

>100_bases
GCTTTAATCGTATTATCTACTTAATACTCATCTTTATTGCCTCTTGGTCGGCCTATTACTTGTACGACAAAGAGCAAACT
TCGACGATACAAGTAGATCC

Product: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MSQTVETLYGTVDSEVFAVAKEIKLLICDVDGVFSDGRIYMGNNGEELKTFHTRDGYGIKSLMNAGVEIAIITGRKSKIV
ENRMTALGIKLIYQGQDDKVKAYQDICDKLSINPENTGYIGDDLIDWPVMAKVGLKVCVADGHPLLAQRANYVTTINGGY
GAVREVCDLILQARSELDVHKGLSI

Sequences:

>Translated_185_residues
MSQTVETLYGTVDSEVFAVAKEIKLLICDVDGVFSDGRIYMGNNGEELKTFHTRDGYGIKSLMNAGVEIAIITGRKSKIV
ENRMTALGIKLIYQGQDDKVKAYQDICDKLSINPENTGYIGDDLIDWPVMAKVGLKVCVADGHPLLAQRANYVTTINGGY
GAVREVCDLILQARSELDVHKGLSI
>Mature_184_residues
SQTVETLYGTVDSEVFAVAKEIKLLICDVDGVFSDGRIYMGNNGEELKTFHTRDGYGIKSLMNAGVEIAIITGRKSKIVE
NRMTALGIKLIYQGQDDKVKAYQDICDKLSINPENTGYIGDDLIDWPVMAKVGLKVCVADGHPLLAQRANYVTTINGGYG
AVREVCDLILQARSELDVHKGLSI

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=153, Percent_Identity=28.1045751633987, Blast_Score=75, Evalue=4e-14,
Organism=Escherichia coli, GI2367202, Length=182, Percent_Identity=62.0879120879121, Blast_Score=234, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 20246; Mature: 20114

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQTVETLYGTVDSEVFAVAKEIKLLICDVDGVFSDGRIYMGNNGEELKTFHTRDGYGIK
CCCHHHHHHCCCCHHHHHHHHHHEEEEECCCCCCCCCEEEECCCCCCEEEEECCCCCCHH
SLMNAGVEIAIITGRKSKIVENRMTALGIKLIYQGQDDKVKAYQDICDKLSINPENTGYI
HHHHCCEEEEEEECCCHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCC
GDDLIDWPVMAKVGLKVCVADGHPLLAQRANYVTTINGGYGAVREVCDLILQARSELDVH
CCCHHCCHHHHHCCEEEEEECCCHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHH
KGLSI
CCCCC
>Mature Secondary Structure 
SQTVETLYGTVDSEVFAVAKEIKLLICDVDGVFSDGRIYMGNNGEELKTFHTRDGYGIK
CCHHHHHHCCCCHHHHHHHHHHEEEEECCCCCCCCCEEEECCCCCCEEEEECCCCCCHH
SLMNAGVEIAIITGRKSKIVENRMTALGIKLIYQGQDDKVKAYQDICDKLSINPENTGYI
HHHHCCEEEEEEECCCHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCC
GDDLIDWPVMAKVGLKVCVADGHPLLAQRANYVTTINGGYGAVREVCDLILQARSELDVH
CCCHHCCHHHHHCCEEEEEECCCHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHH
KGLSI
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]